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The map label for this gene is metH [H]

Identifier: 113476111

GI number: 113476111

Start: 3837647

End: 3841321

Strand: Reverse

Name: metH [H]

Synonym: Tery_2492

Alternate gene names: 113476111

Gene position: 3841321-3837647 (Counterclockwise)

Preceding gene: 113476112

Following gene: 113476110

Centisome position: 49.56

GC content: 44.87

Gene sequence:

>3675_bases
ATGCTAAGTGTTGAAATTCCAAAACCTCAGTTAAAGACTTCATTTCTCCAACGGCTCCAGAGTCCAGATCGCCCAGTACT
GATCTTTGATGGTGCGATGGGAACTAACATCCAATCTCAAAACTTGACCGCCGAGGATTTTGGTGGAGCGGAATATGAAG
GTTGTAATGAATATTTAGTCGTCACGAAGCCAGAAGCAGTGGCGAAAGTCCATCGTGATTTTCTGGCAGCAGGGGCAGAT
GTTGTCGAGACTGATAGCTTTGGATCTAGCCCCTTAGTCCTCGCCGAGTACAATCTAGCCGATCGCGCCTACGAGCTAAG
TAGAAAGGCAGCAGAATTGGCGCGTAGTTGTGCGGATGAGTTTACGAGTCCCGAAAAACCTAGATTCGTCGCAGGTTCCA
TCGGTCCAGGAACCAAGCTACCCACCCTCGGTCATATTACCTATGATGAATTAAAAGCGAGCTTCATGGTGCAAGCAGAA
GGTCTTTATGACGGGGGAGCCGATCTTTTCATAGTGGAAACCTGTCAAGATGTTCTGCAAATTAAGGCAGCATTGAGTGC
CTTTGAGGCGGTATTTGCCAAAAAAGGATCCAGACTCCCCTTAATGGTATCCGTGACCATGGAAATTCAGGGAACTATGT
TGGTGGGAACAGATATCTCTGGGGTGTTAGCAATTCTGGAGCCTTTCCCCATTGATATTTTGGGTCTAAATTGTGCGACA
GGTCCAAATTTGATGACCTCTCATATCAAATATCTATCAGAAAATTCACCATTCCCCATTTCTTGTATTCCCAATGCGGG
GCTACCAGAAAATATTGGCGGTCAGGCTCATTATAAAATGACCCCGCTAGAATTTAAAACGTCCATGTCTGAGTTCATTG
GTCAGTATGGAGTTCAAATTGTCGGTGGCTGCTGCGGTACCCGTCCAGCACATATTCAAGCATTAGCCGATGCTGTGGAA
GAAACCCCACTAAAAGAGCGATCGGTACGAAAAAATGCTGTGGGTAAGGTTAGAACGCCTCTCTCCTATACCCCAGCAGC
AGCTTCCATTTATTCTGCCCAAACCTATGAGCAGGATAATTCTTTTTTAATCGTTGGCGAGCGATTAAATGCCAGTGGTT
CTAAGAAAGTCCGCAAGCTTTTGAATGAAGATGATTGGGATGGGTTATTGGCGATCGCTAAATCCCAGGTCAAAGAAGGC
GCCCATATGCTAGATGTAAACGTGGATTACGTCGGGCGTGATGGAGAACGGGATATGCGAGAACTGGTATCGCGACTGGT
GACTAATACGACCCTCCCACTGATGCTTGACTCCACCGAATGGACCAAAATGGAAGCAGGCCTTAAGGTCGCTGGGGGTA
AATGTTTGCTCAATTCCACCAACTATGAAGATGGAGAAGAGCGATTTTTTAAAGTGTTGGAATTGGCCAAAGAATATGGT
GCAGGAGTTGTCATCGGCTGTATCGATGAAGAGGGAATGGCTAGAACTGCCAAGAAAAAATTTGAGATTGCCCAACGGGC
TTATAAGGATGCCCTCAAGTTTGGAATTCCACCCCATGAAATTTTCTATGATACCTTAGCTCTACCAATTTCAACTGGAA
TTGAGGAGGATCGGGAAAATGCTAAAGCAACGATCGAATCAATTCGACTGATTCGGGAAAATCTGCCCGGTGTCCATTTT
ATGTTAGGGGTCTCTAACATTTCTTTTGGCTTGAGTCCAGCCACTCGCATCACCTTAAATTCGATCTTCCTCAATGAAGC
GATGAAAGCAGGGATGGATGGGGCAATTGTCTCGGCTGCCAAGATTTTACCGTTATCAAAGATTGATGAAGAACATCAAC
AGATCTGTTGCGATTTGATTTATGATAATCGCAAATTTGAAGGGGATATTTGCACCTACGATCCGTTGACGAAGCTAACG
GAAATTTTTGCGGGAGTGAGTGCAAAAGATGCTAGATCTGGCCCTTCCTTAGCAGATTTGCCCATCGACCAACGCTTGAA
GCAACATATTATTGATGGCGAGCGCATTGGATTGGAAGATGCGTTAAAGGTAGCTTTAGATGCCGGTCATAAAGCCCTGG
AGATTATCAATACTTTCTTGCTGGATGGGATGAAGGTTGTAGGGGAACTGTTTGGCTCTGGTCAAATGCAATTACCCTTC
GTGTTGCAGTCAGCCGAAACAATGAAATCTGCGGTAGCTTTCCTTGAACCCTACATGGAAAAAATAGAAGGAGAGGACGA
AGATCGCGGTAAAGGTAAATTCCTGATTGCTACGGTTAAAGGCGATGTCCATGATATCGGGAAAAATCTGGTGGATATCA
TATTGACCAATAATGGCTATAAGGTCATCAATCTGGGCATTAAACAAGCAATTGAGGCAATTGTCGAAGCTTATGAGCAG
CATAAACCTGATTGTATTGCTATGAGTGGCTTGCTGGTGAAATCTACAGCATTCATGAAAGAAAATCTTGCAGCATTTAA
TGCTAAAGGTATTACAGTACCAGTGATTTTAGGTGGTGCTGCACTCACACCAAAATTTGTTTATGGTGATTGTCAAGATA
CTTACCAAGGGCAGGTCATTTACGGTAAAGATGCTTTTGCAGATTTGACCTTTATGGATCGGCTGATGCCCGCCAAAGAT
AAGGATTGCTGGGTCGATACCGAAGGCTTTACAGGGGAGTTTGCTCAGTTTAACCAAAGGGGACGCAAAGCAATCAAAGA
TTTAGAACGAGAACTCAACGGTGATGGGGAGAAATCCGATGGAGAAGTCAATGGTAATGGAAAGAAACCCAATAAACCCA
CTGTAATTGATACTAAACGTTCGACAGACGTAGCGATTGATATCGAACGTCCTGCACCACCTTTCTGGGGCACGAAAATT
CTTCAGAGTGGTGATCTAAAGCTAGAAGAACTGTTCTGGTACATGGATTTACAGGCACTGTTCGCTGGTCAATGGCAATT
CCGTAAACCGAAAGGCCAACCTCGTGAGGAATATGATTGGTTCCTGGCATCAAAGGTTTATCCGATCTTGGAAGAATGGA
AGCAAAAAGTTCGCACTGAACAATGGTTGGAGCCGACTCTAGTTTATGGTTATTTCCCTTGTGCAGCCATCGGCAATTCC
GTTCATGTTTACGATCCGAGTGTTATTGAGCAGGGCTTAACACCTACAACAGCAACCCCGTTTGTCACTTGGACATTCCC
CCGTCAGAAATCCATGCGTCGCCTGTGTATTGCTGATTTCATCCGCCCCCTTGAGCATGATCAATTTGATGTTTTGCCTA
TGCAGGCAGTAACTATGGGAGAAATTGCTACTCAGAAAGCACAGGAACTTTATCAAGGGAACGAGTACACCAATTATCTC
TATTTCCACGGTATGGCGGTGCAGTTGGCGGAAGCCTTAGCAGAATGGAGTCACGCCAGGATTCGGCGGGAGTTAGGTTA
TGGGGATTTAGAGCCAGATAACATTCGCGATATATTAGCTCAAAGGTATCAGGGTTCTCGGTATAGTTTTGGCTATCCAG
CTTGTCCGGTAGTTATCGATCAAGTGCCACAGTTGCAATTATTGGGAGCTGATCGCATTGGGGTATCAATTGATGAGAGC
GAACAGCTTTATCCAGAGCAAACAACTACTGCTTTTGTTATCTATCATCCTGTTGCTAGATATTTTAGTGCTTAG

Upstream 100 bases:

>100_bases
TAATCTGCGAGAATGCAATCTGCAATTCTTTGACTTGCTTTGGGGTAAAAAATAAAAAGGTTGCAGGAGAAGTCTGAGAC
CAACTATAACCATTACGCCT

Downstream 100 bases:

>100_bases
TTAGATCAATTGGGAATGGGGTCGCCCTATCTAGGCGGCCTCTAATTTTTCTTGATAATTGCTAGGCATCAGCATAGCTA
TTGTAGCCTAAGCTTCAACT

Product: methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1224; Mature: 1224

Protein sequence:

>1224_residues
MLSVEIPKPQLKTSFLQRLQSPDRPVLIFDGAMGTNIQSQNLTAEDFGGAEYEGCNEYLVVTKPEAVAKVHRDFLAAGAD
VVETDSFGSSPLVLAEYNLADRAYELSRKAAELARSCADEFTSPEKPRFVAGSIGPGTKLPTLGHITYDELKASFMVQAE
GLYDGGADLFIVETCQDVLQIKAALSAFEAVFAKKGSRLPLMVSVTMEIQGTMLVGTDISGVLAILEPFPIDILGLNCAT
GPNLMTSHIKYLSENSPFPISCIPNAGLPENIGGQAHYKMTPLEFKTSMSEFIGQYGVQIVGGCCGTRPAHIQALADAVE
ETPLKERSVRKNAVGKVRTPLSYTPAAASIYSAQTYEQDNSFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEG
AHMLDVNVDYVGRDGERDMRELVSRLVTNTTLPLMLDSTEWTKMEAGLKVAGGKCLLNSTNYEDGEERFFKVLELAKEYG
AGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEDRENAKATIESIRLIRENLPGVHF
MLGVSNISFGLSPATRITLNSIFLNEAMKAGMDGAIVSAAKILPLSKIDEEHQQICCDLIYDNRKFEGDICTYDPLTKLT
EIFAGVSAKDARSGPSLADLPIDQRLKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPF
VLQSAETMKSAVAFLEPYMEKIEGEDEDRGKGKFLIATVKGDVHDIGKNLVDIILTNNGYKVINLGIKQAIEAIVEAYEQ
HKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGAALTPKFVYGDCQDTYQGQVIYGKDAFADLTFMDRLMPAKD
KDCWVDTEGFTGEFAQFNQRGRKAIKDLERELNGDGEKSDGEVNGNGKKPNKPTVIDTKRSTDVAIDIERPAPPFWGTKI
LQSGDLKLEELFWYMDLQALFAGQWQFRKPKGQPREEYDWFLASKVYPILEEWKQKVRTEQWLEPTLVYGYFPCAAIGNS
VHVYDPSVIEQGLTPTTATPFVTWTFPRQKSMRRLCIADFIRPLEHDQFDVLPMQAVTMGEIATQKAQELYQGNEYTNYL
YFHGMAVQLAEALAEWSHARIRRELGYGDLEPDNIRDILAQRYQGSRYSFGYPACPVVIDQVPQLQLLGADRIGVSIDES
EQLYPEQTTTAFVIYHPVARYFSA

Sequences:

>Translated_1224_residues
MLSVEIPKPQLKTSFLQRLQSPDRPVLIFDGAMGTNIQSQNLTAEDFGGAEYEGCNEYLVVTKPEAVAKVHRDFLAAGAD
VVETDSFGSSPLVLAEYNLADRAYELSRKAAELARSCADEFTSPEKPRFVAGSIGPGTKLPTLGHITYDELKASFMVQAE
GLYDGGADLFIVETCQDVLQIKAALSAFEAVFAKKGSRLPLMVSVTMEIQGTMLVGTDISGVLAILEPFPIDILGLNCAT
GPNLMTSHIKYLSENSPFPISCIPNAGLPENIGGQAHYKMTPLEFKTSMSEFIGQYGVQIVGGCCGTRPAHIQALADAVE
ETPLKERSVRKNAVGKVRTPLSYTPAAASIYSAQTYEQDNSFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEG
AHMLDVNVDYVGRDGERDMRELVSRLVTNTTLPLMLDSTEWTKMEAGLKVAGGKCLLNSTNYEDGEERFFKVLELAKEYG
AGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEDRENAKATIESIRLIRENLPGVHF
MLGVSNISFGLSPATRITLNSIFLNEAMKAGMDGAIVSAAKILPLSKIDEEHQQICCDLIYDNRKFEGDICTYDPLTKLT
EIFAGVSAKDARSGPSLADLPIDQRLKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPF
VLQSAETMKSAVAFLEPYMEKIEGEDEDRGKGKFLIATVKGDVHDIGKNLVDIILTNNGYKVINLGIKQAIEAIVEAYEQ
HKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGAALTPKFVYGDCQDTYQGQVIYGKDAFADLTFMDRLMPAKD
KDCWVDTEGFTGEFAQFNQRGRKAIKDLERELNGDGEKSDGEVNGNGKKPNKPTVIDTKRSTDVAIDIERPAPPFWGTKI
LQSGDLKLEELFWYMDLQALFAGQWQFRKPKGQPREEYDWFLASKVYPILEEWKQKVRTEQWLEPTLVYGYFPCAAIGNS
VHVYDPSVIEQGLTPTTATPFVTWTFPRQKSMRRLCIADFIRPLEHDQFDVLPMQAVTMGEIATQKAQELYQGNEYTNYL
YFHGMAVQLAEALAEWSHARIRRELGYGDLEPDNIRDILAQRYQGSRYSFGYPACPVVIDQVPQLQLLGADRIGVSIDES
EQLYPEQTTTAFVIYHPVARYFSA
>Mature_1224_residues
MLSVEIPKPQLKTSFLQRLQSPDRPVLIFDGAMGTNIQSQNLTAEDFGGAEYEGCNEYLVVTKPEAVAKVHRDFLAAGAD
VVETDSFGSSPLVLAEYNLADRAYELSRKAAELARSCADEFTSPEKPRFVAGSIGPGTKLPTLGHITYDELKASFMVQAE
GLYDGGADLFIVETCQDVLQIKAALSAFEAVFAKKGSRLPLMVSVTMEIQGTMLVGTDISGVLAILEPFPIDILGLNCAT
GPNLMTSHIKYLSENSPFPISCIPNAGLPENIGGQAHYKMTPLEFKTSMSEFIGQYGVQIVGGCCGTRPAHIQALADAVE
ETPLKERSVRKNAVGKVRTPLSYTPAAASIYSAQTYEQDNSFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEG
AHMLDVNVDYVGRDGERDMRELVSRLVTNTTLPLMLDSTEWTKMEAGLKVAGGKCLLNSTNYEDGEERFFKVLELAKEYG
AGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEDRENAKATIESIRLIRENLPGVHF
MLGVSNISFGLSPATRITLNSIFLNEAMKAGMDGAIVSAAKILPLSKIDEEHQQICCDLIYDNRKFEGDICTYDPLTKLT
EIFAGVSAKDARSGPSLADLPIDQRLKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPF
VLQSAETMKSAVAFLEPYMEKIEGEDEDRGKGKFLIATVKGDVHDIGKNLVDIILTNNGYKVINLGIKQAIEAIVEAYEQ
HKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGAALTPKFVYGDCQDTYQGQVIYGKDAFADLTFMDRLMPAKD
KDCWVDTEGFTGEFAQFNQRGRKAIKDLERELNGDGEKSDGEVNGNGKKPNKPTVIDTKRSTDVAIDIERPAPPFWGTKI
LQSGDLKLEELFWYMDLQALFAGQWQFRKPKGQPREEYDWFLASKVYPILEEWKQKVRTEQWLEPTLVYGYFPCAAIGNS
VHVYDPSVIEQGLTPTTATPFVTWTFPRQKSMRRLCIADFIRPLEHDQFDVLPMQAVTMGEIATQKAQELYQGNEYTNYL
YFHGMAVQLAEALAEWSHARIRRELGYGDLEPDNIRDILAQRYQGSRYSFGYPACPVVIDQVPQLQLLGADRIGVSIDES
EQLYPEQTTTAFVIYHPVARYFSA

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1255, Percent_Identity=31.1553784860558, Blast_Score=533, Evalue=1e-151,
Organism=Escherichia coli, GI1790450, Length=1248, Percent_Identity=31.1698717948718, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1786456, Length=313, Percent_Identity=27.4760383386581, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17535405, Length=1260, Percent_Identity=32.1428571428571, Blast_Score=538, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6322966, Length=319, Percent_Identity=24.4514106583072, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 135277; Mature: 135277

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVEIPKPQLKTSFLQRLQSPDRPVLIFDGAMGTNIQSQNLTAEDFGGAEYEGCNEYLV
CCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEE
VTKPEAVAKVHRDFLAAGADVVETDSFGSSPLVLAEYNLADRAYELSRKAAELARSCADE
EECCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
FTSPEKPRFVAGSIGPGTKLPTLGHITYDELKASFMVQAEGLYDGGADLFIVETCQDVLQ
CCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCEEEHHHHHHHHH
IKAALSAFEAVFAKKGSRLPLMVSVTMEIQGTMLVGTDISGVLAILEPFPIDILGLNCAT
HHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCC
GPNLMTSHIKYLSENSPFPISCIPNAGLPENIGGQAHYKMTPLEFKTSMSEFIGQYGVQI
CCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCHHE
VGGCCGTRPAHIQALADAVEETPLKERSVRKNAVGKVRTPLSYTPAAASIYSAQTYEQDN
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
SFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEGAHMLDVNVDYVGRDGERDMR
CEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHH
ELVSRLVTNTTLPLMLDSTEWTKMEAGLKVAGGKCLLNSTNYEDGEERFFKVLELAKEYG
HHHHHHHHCCCCEEEECCCCHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHC
AGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEDREN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
AKATIESIRLIRENLPGVHFMLGVSNISFGLSPATRITLNSIFLNEAMKAGMDGAIVSAA
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCCCCCHHHHHH
KILPLSKIDEEHQQICCDLIYDNRKFEGDICTYDPLTKLTEIFAGVSAKDARSGPSLADL
HHCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PIDQRLKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPF
CHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VLQSAETMKSAVAFLEPYMEKIEGEDEDRGKGKFLIATVKGDVHDIGKNLVDIILTNNGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCEEEEEEECCCE
KVINLGIKQAIEAIVEAYEQHKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGA
EEEECCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
ALTPKFVYGDCQDTYQGQVIYGKDAFADLTFMDRLMPAKDKDCWVDTEGFTGEFAQFNQR
CCCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHH
GRKAIKDLERELNGDGEKSDGEVNGNGKKPNKPTVIDTKRSTDVAIDIERPAPPFWGTKI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCHHH
LQSGDLKLEELFWYMDLQALFAGQWQFRKPKGQPREEYDWFLASKVYPILEEWKQKVRTE
HCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QWLEPTLVYGYFPCAAIGNSVHVYDPSVIEQGLTPTTATPFVTWTFPRQKSMRRLCIADF
HCCCCEEEEECCHHHHCCCEEEEECHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
IRPLEHDQFDVLPMQAVTMGEIATQKAQELYQGNEYTNYLYFHGMAVQLAEALAEWSHAR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
IRRELGYGDLEPDNIRDILAQRYQGSRYSFGYPACPVVIDQVPQLQLLGADRIGVSIDES
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCEECCC
EQLYPEQTTTAFVIYHPVARYFSA
CCCCCCCCCEEEEEEHHHHHHHCC
>Mature Secondary Structure
MLSVEIPKPQLKTSFLQRLQSPDRPVLIFDGAMGTNIQSQNLTAEDFGGAEYEGCNEYLV
CCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEE
VTKPEAVAKVHRDFLAAGADVVETDSFGSSPLVLAEYNLADRAYELSRKAAELARSCADE
EECCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
FTSPEKPRFVAGSIGPGTKLPTLGHITYDELKASFMVQAEGLYDGGADLFIVETCQDVLQ
CCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCEEEHHHHHHHHH
IKAALSAFEAVFAKKGSRLPLMVSVTMEIQGTMLVGTDISGVLAILEPFPIDILGLNCAT
HHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCC
GPNLMTSHIKYLSENSPFPISCIPNAGLPENIGGQAHYKMTPLEFKTSMSEFIGQYGVQI
CCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCHHE
VGGCCGTRPAHIQALADAVEETPLKERSVRKNAVGKVRTPLSYTPAAASIYSAQTYEQDN
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
SFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEGAHMLDVNVDYVGRDGERDMR
CEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHH
ELVSRLVTNTTLPLMLDSTEWTKMEAGLKVAGGKCLLNSTNYEDGEERFFKVLELAKEYG
HHHHHHHHCCCCEEEECCCCHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHC
AGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEDREN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
AKATIESIRLIRENLPGVHFMLGVSNISFGLSPATRITLNSIFLNEAMKAGMDGAIVSAA
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCCCCCHHHHHH
KILPLSKIDEEHQQICCDLIYDNRKFEGDICTYDPLTKLTEIFAGVSAKDARSGPSLADL
HHCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PIDQRLKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPF
CHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VLQSAETMKSAVAFLEPYMEKIEGEDEDRGKGKFLIATVKGDVHDIGKNLVDIILTNNGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCEEEEEEECCCE
KVINLGIKQAIEAIVEAYEQHKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGA
EEEECCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
ALTPKFVYGDCQDTYQGQVIYGKDAFADLTFMDRLMPAKDKDCWVDTEGFTGEFAQFNQR
CCCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHH
GRKAIKDLERELNGDGEKSDGEVNGNGKKPNKPTVIDTKRSTDVAIDIERPAPPFWGTKI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCHHH
LQSGDLKLEELFWYMDLQALFAGQWQFRKPKGQPREEYDWFLASKVYPILEEWKQKVRTE
HCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QWLEPTLVYGYFPCAAIGNSVHVYDPSVIEQGLTPTTATPFVTWTFPRQKSMRRLCIADF
HCCCCEEEEECCHHHHCCCEEEEECHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
IRPLEHDQFDVLPMQAVTMGEIATQKAQELYQGNEYTNYLYFHGMAVQLAEALAEWSHAR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
IRRELGYGDLEPDNIRDILAQRYQGSRYSFGYPACPVVIDQVPQLQLLGADRIGVSIDES
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCEECCC
EQLYPEQTTTAFVIYHPVARYFSA
CCCCCCCCCEEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]