Click here to switch to the map view.

The map label for this gene is lysA [H]

Identifier: 113476062

GI number: 113476062

Start: 3751594

End: 3753021

Strand: Reverse

Name: lysA [H]

Synonym: Tery_2435

Alternate gene names: 113476062

Gene position: 3753021-3751594 (Counterclockwise)

Preceding gene: 113476065

Following gene: 113476061

Centisome position: 48.43

GC content: 36.27

Gene sequence:

>1428_bases
ATGGTATCAATCCAATCTGTAGAAGTAAACTCTGGACTTCAGTATTTGCCAAAATCAACAGACTCTGTTGGACAAAGTTC
GCCCAATCAAGAACTTTTACCACTTACTGCTAAAGTCAACAACTTAGACCATTTAGAAATTGGAGGTTGGGATATCCCAG
CATTAGTAGAAAAATTTGGCTCACCTCTATATATTATAGACGAATATACTCTCCGAACAGCTTGTCGCCAATATAGAGAT
GGACTTCAAAAGTACTATCCTGGAGAATCTTTAGTACTTTATGCTTCCAAAGCTTGGAGTAGTCTAGCAGTATGTGCCTT
ATGTGCCTCTGAAGGCTTAGGTATAGATGTTGTATCTGGAGGAGAACTATATACAGCTATAGAAGCAGGTGTTAATCCTG
ACAAAATATATTTTCATGGCAATAATAAATCTCTGGCAGAATTAACTTTTGCCATTGAAACAGATTGTATAATTGTTGTA
GATAACTGGCTAGAATTAGAAACATTAGCAGGTTTAAAGAAGCAACAAAAAGATCAGGTACAAAATCCGACAAAAATAAT
GGTAAGATTTACACCTGGTATTGAATGCCATACCCACGAATATATTCGTACAGGTCATCTAGATAGCAAGTTTGGATTTG
ATCCAGGTCAACTAAATGATGTTTTTGCCTTCATAAGTAAAGAAGAATTACTACTACTTATTGGTGTTCATGCTCATATA
GGTTCTCAGATTTTTGAAGTTCAACCTCATCAAGATTTAGTGACTGTTATGGTAGATACAATGACAACTGCCATGTCACA
TAACTTGCCAATCAAAGAAATTAATATTGGTGGTGGTTTAGGAATCCGTTATACTGAAACAGATGACCCCCCTAGTATTG
AAACTTGGGTTCATAAGGTAAGCACAGCAATGGTAGATGTTTGTAAAGCTAGACAGTTACCACTTCCTAAACTATTATGT
GAACCGGGACGCTCAATAATTGGGCCTGCCTGTATAACAGCTTATACTATAGGGTCTCAAAAAGAAATTCCTGAAATTAG
AACTTATATATCTGTAGATGGGGGAATGTCAGATAATCCTCGACCAATTACTTATCAATCAGTTTATCGAGCAATTGTAG
CTAATAGATTATCTAAGCCAAGCACAGAAGTAGTTACTATTGCTGGTAAACATTGTGAGTCTGGTGATATTTTGATCAAG
AATGCTACCTTACCAGTAACTCAACCAGGAGATTGTTTTGTAGTTATGGCTACAGGTGCTTACAATTATAGTATGGCTTC
TAACTATAATCGTTTGCCACGCCCAGCAGCAGTTTTGGTTGCTGAAAAGGAGGTTAATATAATTTTACAGAGGGAAACTT
ATCAAGATTTACTTAGTAAAGATACTTTACCAGAACGAATAGCAACACTTCCAAAGTTAACAACATGA

Upstream 100 bases:

>100_bases
ATAGTCTTAATTTTAGATAAAAAATTAATCAAGAATTGACAAAGTATAATAAATTGTATTTATTATATAGGCCACTAAAG
TATAAATTTTTATAGCACTT

Downstream 100 bases:

>100_bases
CAATTAAAAATTACCTCTTCTTTTAAAGAATAGTATTAACTAAAATAAAATTTGTCTTAATTTTAGCCTTTAGGATAGTT
TTTCTTAATAAAAAAGCTAG

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MVSIQSVEVNSGLQYLPKSTDSVGQSSPNQELLPLTAKVNNLDHLEIGGWDIPALVEKFGSPLYIIDEYTLRTACRQYRD
GLQKYYPGESLVLYASKAWSSLAVCALCASEGLGIDVVSGGELYTAIEAGVNPDKIYFHGNNKSLAELTFAIETDCIIVV
DNWLELETLAGLKKQQKDQVQNPTKIMVRFTPGIECHTHEYIRTGHLDSKFGFDPGQLNDVFAFISKEELLLLIGVHAHI
GSQIFEVQPHQDLVTVMVDTMTTAMSHNLPIKEINIGGGLGIRYTETDDPPSIETWVHKVSTAMVDVCKARQLPLPKLLC
EPGRSIIGPACITAYTIGSQKEIPEIRTYISVDGGMSDNPRPITYQSVYRAIVANRLSKPSTEVVTIAGKHCESGDILIK
NATLPVTQPGDCFVVMATGAYNYSMASNYNRLPRPAAVLVAEKEVNIILQRETYQDLLSKDTLPERIATLPKLTT

Sequences:

>Translated_475_residues
MVSIQSVEVNSGLQYLPKSTDSVGQSSPNQELLPLTAKVNNLDHLEIGGWDIPALVEKFGSPLYIIDEYTLRTACRQYRD
GLQKYYPGESLVLYASKAWSSLAVCALCASEGLGIDVVSGGELYTAIEAGVNPDKIYFHGNNKSLAELTFAIETDCIIVV
DNWLELETLAGLKKQQKDQVQNPTKIMVRFTPGIECHTHEYIRTGHLDSKFGFDPGQLNDVFAFISKEELLLLIGVHAHI
GSQIFEVQPHQDLVTVMVDTMTTAMSHNLPIKEINIGGGLGIRYTETDDPPSIETWVHKVSTAMVDVCKARQLPLPKLLC
EPGRSIIGPACITAYTIGSQKEIPEIRTYISVDGGMSDNPRPITYQSVYRAIVANRLSKPSTEVVTIAGKHCESGDILIK
NATLPVTQPGDCFVVMATGAYNYSMASNYNRLPRPAAVLVAEKEVNIILQRETYQDLLSKDTLPERIATLPKLTT
>Mature_475_residues
MVSIQSVEVNSGLQYLPKSTDSVGQSSPNQELLPLTAKVNNLDHLEIGGWDIPALVEKFGSPLYIIDEYTLRTACRQYRD
GLQKYYPGESLVLYASKAWSSLAVCALCASEGLGIDVVSGGELYTAIEAGVNPDKIYFHGNNKSLAELTFAIETDCIIVV
DNWLELETLAGLKKQQKDQVQNPTKIMVRFTPGIECHTHEYIRTGHLDSKFGFDPGQLNDVFAFISKEELLLLIGVHAHI
GSQIFEVQPHQDLVTVMVDTMTTAMSHNLPIKEINIGGGLGIRYTETDDPPSIETWVHKVSTAMVDVCKARQLPLPKLLC
EPGRSIIGPACITAYTIGSQKEIPEIRTYISVDGGMSDNPRPITYQSVYRAIVANRLSKPSTEVVTIAGKHCESGDILIK
NATLPVTQPGDCFVVMATGAYNYSMASNYNRLPRPAAVLVAEKEVNIILQRETYQDLLSKDTLPERIATLPKLTT

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=422, Percent_Identity=27.4881516587678, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 52214; Mature: 52214

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIQSVEVNSGLQYLPKSTDSVGQSSPNQELLPLTAKVNNLDHLEIGGWDIPALVEKFG
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHHHHHCC
SPLYIIDEYTLRTACRQYRDGLQKYYPGESLVLYASKAWSSLAVCALCASEGLGIDVVSG
CCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECC
GELYTAIEAGVNPDKIYFHGNNKSLAELTFAIETDCIIVVDNWLELETLAGLKKQQKDQV
CCEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHH
QNPTKIMVRFTPGIECHTHEYIRTGHLDSKFGFDPGQLNDVFAFISKEELLLLIGVHAHI
CCCEEEEEEECCCCEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEHHHH
GSQIFEVQPHQDLVTVMVDTMTTAMSHNLPIKEINIGGGLGIRYTETDDPPSIETWVHKV
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHH
STAMVDVCKARQLPLPKLLCEPGRSIIGPACITAYTIGSQKEIPEIRTYISVDGGMSDNP
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCCCCC
RPITYQSVYRAIVANRLSKPSTEVVTIAGKHCESGDILIKNATLPVTQPGDCFVVMATGA
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCEECCCCCCCEEEEEEECC
YNYSMASNYNRLPRPAAVLVAEKEVNIILQRETYQDLLSKDTLPERIATLPKLTT
CCCHHHCCCCCCCCCEEEEEEECCEEEEEEHHHHHHHHHCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MVSIQSVEVNSGLQYLPKSTDSVGQSSPNQELLPLTAKVNNLDHLEIGGWDIPALVEKFG
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHHHHHCC
SPLYIIDEYTLRTACRQYRDGLQKYYPGESLVLYASKAWSSLAVCALCASEGLGIDVVSG
CCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECC
GELYTAIEAGVNPDKIYFHGNNKSLAELTFAIETDCIIVVDNWLELETLAGLKKQQKDQV
CCEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHH
QNPTKIMVRFTPGIECHTHEYIRTGHLDSKFGFDPGQLNDVFAFISKEELLLLIGVHAHI
CCCEEEEEEECCCCEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEHHHH
GSQIFEVQPHQDLVTVMVDTMTTAMSHNLPIKEINIGGGLGIRYTETDDPPSIETWVHKV
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHH
STAMVDVCKARQLPLPKLLCEPGRSIIGPACITAYTIGSQKEIPEIRTYISVDGGMSDNP
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCCCCC
RPITYQSVYRAIVANRLSKPSTEVVTIAGKHCESGDILIKNATLPVTQPGDCFVVMATGA
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCEECCCCCCCEEEEEEECC
YNYSMASNYNRLPRPAAVLVAEKEVNIILQRETYQDLLSKDTLPERIATLPKLTT
CCCHHHCCCCCCCCCEEEEEEECCEEEEEEHHHHHHHHHCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]