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The map label for this gene is pkn1 [H]

Identifier: 113476044

GI number: 113476044

Start: 3724002

End: 3725813

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_2415

Alternate gene names: 113476044

Gene position: 3725813-3724002 (Counterclockwise)

Preceding gene: 113476052

Following gene: 113476043

Centisome position: 48.07

GC content: 37.03

Gene sequence:

>1812_bases
ATGCCAGAAAAACAGCGGGAAAATTATTTCATACTTTTGGGAATAGATCCAAAAGAATCTTGGTCTGATGAAAAATTCGA
GGAAATTCTAATACAAAAACGTGCAGAGTGGTCGGCAAAAAGCAAATTACCAGGAAGAAAAGGGGCGCAGTATCGAGAAT
ATTTAGCTCTAATTCCTGAAATTAAAAAGATTATGGGGGACCCTGGTCAAAGAGCAAAAGAAGCAGAAATGGCAAAGACT
AGCCAGCAAGAGACTCCAGGCAAAGTAGAACAAGAAAAATTAATAACAGAAATAGACTTAATTTCTAGTAAAGGATTTAT
TTACGAATCGGAAATTCAAGGGTTAGTTAGAAAATATAAAAATTTTGTTCCAGAATCATTTATCAGAAATGAAATCAACA
GAAACAATATTCAAATTAATCAAGATGTCGATGAACCAAATTTAGAAACTTTAGATGAAACACAATTAAAAAGAATTAAA
GGGTATTTAGAGACATTAGGTTACCAAAATATTTACGAATTTTTAGAACTATCAAAAACCACGGCAAAGAACAATATTTT
TATTGATAGAGCTCAGGAAAAATACGAAAAATCACAAAAAAGTGGGCGAAAAGATACGAAAACGGAAGCTCAAAGAGGTC
TGGCAATAGAAAGTAAAAATATTTTTGCCACAGAAAAAACTCGTAGACTATATGATAATTCTTTAGAACTTGAGGAATAT
AAAACTATCAAGGACAATATTCAAAGTCTTGCTCAAATTTCTTCTGATAAGATTCTTTATCCCAAACAATTTGATAAGAT
TCTCAAAATAGCTCAGTCATCGGGGATAGAGAATGTAGAAAAAGCTAAAAAAGTGATTATTAAATATGCTAGGGAAAACA
ATTTATCCCTAGAATTTCTTGATATGAATAATGATTTATCAACAGCGATCGCTAATTATTCTAGGGAAACTGAACAAGTT
AGACAAAAACAAACTCCTCCACCACGACCAAAAATTCCCATTCAGACGTTTACCACTGTGAGAGTTAACAGTAGAGGAAA
CATAATAAGTCGCAGTGAAGGTAAAGCAGAAGTAATGACAGAAAACATCGGTAATGGAGTTTCTCTAGAAATGGTAAAAA
TTCCCGGAGGTATATTCCTCATGGGGTCTCCAGAGACTGAAGCAGAAAGAGATGATGATGAAGGTCCGCAACATTATGTA
AATGTGCCAGAATTTTTCATGGGCAAGTATCCAGTCACTCAAGCACAATGGCAAGCAGTTATGGGAAACAACCCTTCTCG
TTTTGAAGGAAAAAATCGCCCTGTAGAAAGGGTAAGTTGGAATGACGCTACAGAGTTCTGTCAAAAGCTCTCTAAGAAAA
CGGGAAGAGACTATAGACTGCCGAGCGAAGCAGAATGGGAATATGCCTGTCGTGGAGGAACAACAACACCATTTTATTTT
GGAGAAACCATAACGTCTGAGTTAGTCAACTATGATGGCAGGTACACTTACGGTAATGGGCCAAAAGGAAAATATAGAAA
AGAAACAACAGATGTGGGAAATTTTCCACCCAATAGTTTTGGCTTGTACGATATGCACGGGAATGTCTGGGAATGGTGTG
CTGATGAATGGCATGATAACTATGATGGTGCGCCTACAGATGGCAGTGTTTGGCTAAATGGAAATAAAAGTCTATCACCG
CTGCGGGGCGGTTCTTGGATCAGCTATCCTTATATTTGCCGTTCTGCGGTTCGCTACTACTTTATTAGGCGCGACGTCCA
CAACTACATTACTGGTTTTCGTCTTGTCTGCGATGGCGGGAGAACTCTCTAA

Upstream 100 bases:

>100_bases
GAATTAAATACTTTTAATTTAACCGGACTTTAGGAAAAATCAAAATAAGGTTAAAATCATATTTAGTCGAATATTTGCAG
AGTAAAGTTTTGAGACTATT

Downstream 100 bases:

>100_bases
CCCTTTTCTCTTTTCCCCTTTTGCCCTTTGCCCTGTTTTTCTTTTTCCTTTATTGTCCCGCTTTAGCGGGTCGATTTTTT
TTTGCTACCATATAATACTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MPEKQRENYFILLGIDPKESWSDEKFEEILIQKRAEWSAKSKLPGRKGAQYREYLALIPEIKKIMGDPGQRAKEAEMAKT
SQQETPGKVEQEKLITEIDLISSKGFIYESEIQGLVRKYKNFVPESFIRNEINRNNIQINQDVDEPNLETLDETQLKRIK
GYLETLGYQNIYEFLELSKTTAKNNIFIDRAQEKYEKSQKSGRKDTKTEAQRGLAIESKNIFATEKTRRLYDNSLELEEY
KTIKDNIQSLAQISSDKILYPKQFDKILKIAQSSGIENVEKAKKVIIKYARENNLSLEFLDMNNDLSTAIANYSRETEQV
RQKQTPPPRPKIPIQTFTTVRVNSRGNIISRSEGKAEVMTENIGNGVSLEMVKIPGGIFLMGSPETEAERDDDEGPQHYV
NVPEFFMGKYPVTQAQWQAVMGNNPSRFEGKNRPVERVSWNDATEFCQKLSKKTGRDYRLPSEAEWEYACRGGTTTPFYF
GETITSELVNYDGRYTYGNGPKGKYRKETTDVGNFPPNSFGLYDMHGNVWEWCADEWHDNYDGAPTDGSVWLNGNKSLSP
LRGGSWISYPYICRSAVRYYFIRRDVHNYITGFRLVCDGGRTL

Sequences:

>Translated_603_residues
MPEKQRENYFILLGIDPKESWSDEKFEEILIQKRAEWSAKSKLPGRKGAQYREYLALIPEIKKIMGDPGQRAKEAEMAKT
SQQETPGKVEQEKLITEIDLISSKGFIYESEIQGLVRKYKNFVPESFIRNEINRNNIQINQDVDEPNLETLDETQLKRIK
GYLETLGYQNIYEFLELSKTTAKNNIFIDRAQEKYEKSQKSGRKDTKTEAQRGLAIESKNIFATEKTRRLYDNSLELEEY
KTIKDNIQSLAQISSDKILYPKQFDKILKIAQSSGIENVEKAKKVIIKYARENNLSLEFLDMNNDLSTAIANYSRETEQV
RQKQTPPPRPKIPIQTFTTVRVNSRGNIISRSEGKAEVMTENIGNGVSLEMVKIPGGIFLMGSPETEAERDDDEGPQHYV
NVPEFFMGKYPVTQAQWQAVMGNNPSRFEGKNRPVERVSWNDATEFCQKLSKKTGRDYRLPSEAEWEYACRGGTTTPFYF
GETITSELVNYDGRYTYGNGPKGKYRKETTDVGNFPPNSFGLYDMHGNVWEWCADEWHDNYDGAPTDGSVWLNGNKSLSP
LRGGSWISYPYICRSAVRYYFIRRDVHNYITGFRLVCDGGRTL
>Mature_602_residues
PEKQRENYFILLGIDPKESWSDEKFEEILIQKRAEWSAKSKLPGRKGAQYREYLALIPEIKKIMGDPGQRAKEAEMAKTS
QQETPGKVEQEKLITEIDLISSKGFIYESEIQGLVRKYKNFVPESFIRNEINRNNIQINQDVDEPNLETLDETQLKRIKG
YLETLGYQNIYEFLELSKTTAKNNIFIDRAQEKYEKSQKSGRKDTKTEAQRGLAIESKNIFATEKTRRLYDNSLELEEYK
TIKDNIQSLAQISSDKILYPKQFDKILKIAQSSGIENVEKAKKVIIKYARENNLSLEFLDMNNDLSTAIANYSRETEQVR
QKQTPPPRPKIPIQTFTTVRVNSRGNIISRSEGKAEVMTENIGNGVSLEMVKIPGGIFLMGSPETEAERDDDEGPQHYVN
VPEFFMGKYPVTQAQWQAVMGNNPSRFEGKNRPVERVSWNDATEFCQKLSKKTGRDYRLPSEAEWEYACRGGTTTPFYFG
ETITSELVNYDGRYTYGNGPKGKYRKETTDVGNFPPNSFGLYDMHGNVWEWCADEWHDNYDGAPTDGSVWLNGNKSLSPL
RGGSWISYPYICRSAVRYYFIRRDVHNYITGFRLVCDGGRTL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=200, Percent_Identity=31.5, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI257470977, Length=225, Percent_Identity=28, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38202250, Length=225, Percent_Identity=28, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI194248087, Length=284, Percent_Identity=29.5774647887324, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI194248088, Length=299, Percent_Identity=28.0936454849498, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI226437577, Length=199, Percent_Identity=33.1658291457286, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130397, Length=231, Percent_Identity=29.4372294372294, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 69409; Mature: 69278

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKQRENYFILLGIDPKESWSDEKFEEILIQKRAEWSAKSKLPGRKGAQYREYLALIPE
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
IKKIMGDPGQRAKEAEMAKTSQQETPGKVEQEKLITEIDLISSKGFIYESEIQGLVRKYK
HHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
NFVPESFIRNEINRNNIQINQDVDEPNLETLDETQLKRIKGYLETLGYQNIYEFLELSKT
HHCCHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
TAKNNIFIDRAQEKYEKSQKSGRKDTKTEAQRGLAIESKNIFATEKTRRLYDNSLELEEY
HCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCEEECHHHHHHHCCCCCHHHH
KTIKDNIQSLAQISSDKILYPKQFDKILKIAQSSGIENVEKAKKVIIKYARENNLSLEFL
HHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEE
DMNNDLSTAIANYSRETEQVRQKQTPPPRPKIPIQTFTTVRVNSRGNIISRSEGKAEVMT
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHH
ENIGNGVSLEMVKIPGGIFLMGSPETEAERDDDEGPQHYVNVPEFFMGKYPVTQAQWQAV
HHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCHHCCCCHHHHCCCCCCCHHHHHHH
MGNNPSRFEGKNRPVERVSWNDATEFCQKLSKKTGRDYRLPSEAEWEYACRGGTTTPFYF
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEC
GETITSELVNYDGRYTYGNGPKGKYRKETTDVGNFPPNSFGLYDMHGNVWEWCADEWHDN
CHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCC
YDGAPTDGSVWLNGNKSLSPLRGGSWISYPYICRSAVRYYFIRRDVHNYITGFRLVCDGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
RTL
CCC
>Mature Secondary Structure 
PEKQRENYFILLGIDPKESWSDEKFEEILIQKRAEWSAKSKLPGRKGAQYREYLALIPE
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
IKKIMGDPGQRAKEAEMAKTSQQETPGKVEQEKLITEIDLISSKGFIYESEIQGLVRKYK
HHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
NFVPESFIRNEINRNNIQINQDVDEPNLETLDETQLKRIKGYLETLGYQNIYEFLELSKT
HHCCHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
TAKNNIFIDRAQEKYEKSQKSGRKDTKTEAQRGLAIESKNIFATEKTRRLYDNSLELEEY
HCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCEEECHHHHHHHCCCCCHHHH
KTIKDNIQSLAQISSDKILYPKQFDKILKIAQSSGIENVEKAKKVIIKYARENNLSLEFL
HHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEE
DMNNDLSTAIANYSRETEQVRQKQTPPPRPKIPIQTFTTVRVNSRGNIISRSEGKAEVMT
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHH
ENIGNGVSLEMVKIPGGIFLMGSPETEAERDDDEGPQHYVNVPEFFMGKYPVTQAQWQAV
HHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCHHCCCCHHHHCCCCCCCHHHHHHH
MGNNPSRFEGKNRPVERVSWNDATEFCQKLSKKTGRDYRLPSEAEWEYACRGGTTTPFYF
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEC
GETITSELVNYDGRYTYGNGPKGKYRKETTDVGNFPPNSFGLYDMHGNVWEWCADEWHDN
CHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCC
YDGAPTDGSVWLNGNKSLSPLRGGSWISYPYICRSAVRYYFIRRDVHNYITGFRLVCDGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
RTL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]