Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 113475804

GI number: 113475804

Start: 3368523

End: 3370517

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_2158

Alternate gene names: 113475804

Gene position: 3370517-3368523 (Counterclockwise)

Preceding gene: 113475805

Following gene: 113475803

Centisome position: 43.49

GC content: 39.1

Gene sequence:

>1995_bases
ATGAATGAAACTCAACAACTACCTATATCAATTCAACCTATAATTAACTATCCCCATTCGGCAGAAGTGGGTAAAACTTA
TTTGATGGAAATTGATATTAAACAAACTGAGGATTTTGAAAAATGGAATTATGAGGAGGAAGAATATCCTATTTATTTTC
GGGTAGATACCTATTGTCAAGGAGATACTACTCCATTATTTAAGATTCAAATTATCGGCGAACCTGCAGTGGTTTTACAT
CGCTTTGGGGGGACTTACGGCCCGGCAAAATTTTTATTAACTGCTGCTCAAAAGGAGATGGAAGGAGAGATTAGAGTAAC
TTTGGTTAATGGTTGGGGCGTACCTCTCAAAAGGTTGCGTTTGGAGAATGTGGCTGTAGTTGCGGATAAACAAGATGACT
CAATTATTGCTGGAGTTAAGGTTAGAAATAATCACGCGATCGCTATGGGCATTAACCAATATAATTATCTACCATCTCTA
AGATATGCTGTTAAAGATGCAGAGGTAATAAAAAATTGGTTTGAGCAGAAAAACTTTAGCAAGGTTGATTTATTTACAGA
AGTAATTTCAGTGAGACTTAAGAGGTTTTTGGCAGAGAAATTTGAGAAACCTTTCCTCTCAGCAGAAGATAATTTTTGGT
TTTTCTTTAGTGGCTACGGTGAGTGTATAGAAGATGTAGACTATCTCATCCCAGCAGATAGTCAAAAGGATGACTTCAGA
ACAACTGCTATTTCTGTTAATTCTCTTGTAGAAAAATTATTTTCTTCTGGTGCAGGAAAAGTAATTTTGTTCTTAGATAC
TAACTATATCTCTGGTGAAATTTCTTTCTTTTCCGGTTTTTCTTTTTCTGTTAAAGATGGGCAGGAACTGATAGTTTTCT
TGAGTAAAGAAGCTAATGAAGTTGAGCAACTTCAGCAGGGAAGTTTTACTTATGCTTTACACGAAGCACTCCGGTCGAGT
GAAGGGAGTTTGAGTATAAATCAACTTCAGAAGTTTTTGAGCGATCGCGGTCGGGAACTTAACAAACGGAATAACCAGCA
GAGGCAAATTCTACAAAAGTTTATTTCTCCCAAAAATTTGGGAGAATGGGTTCCTTTTCCTTCAGACTTTCAGGTTTTTC
AGTATACAACACCTACAGTTGACGGAGGGGGAAAAATTATCAAGCAAGATACTAAGCTTACCCAATACTTTAGGGAAACT
ATTGCGCAACAGTTAGAACTAGAAATGGTAATTATTCCTGGTGGTAACTTTACCATGGGTTCTCCTGAAAGTGAAGAGGG
TAGCTATCATGATGAACGCCCCCAAAACGATGTGACTGTCTCTCCCTTTTTTATGGGCAAATATCCGGTTACTCAAGGAC
AGTGGAGAGCGATCGCTTCTCAGACAAACTTGAAAGTAAATTTAGACCTAGACCCAGAGCCATCATACTTTAAGGAACCA
TATCAAGATATAGATAGATGGGAGAGACCAGTTGAGAAGGTAAACTGGTACCAAGCAGTAGAGTTCTGTGAAAGACTATC
GAAATTAACAGGAAGGAATTATAGACTACCCAGTGAAGCAGAGTGGGAATATGCTTGCCGTGCAGGAACCACTACACCTT
TCTACTTTGGAGAAACTATAACATCTGAGTTAGTTAACTATAATGGCAACTATTACGGGAATGGGCCCAAAGGAGAATAT
AGAAACCAAACTACTCCTGTAGGTCAATTTCCACCAAATGCTTTTGGATTATATGATATGCACGGAAATGTATGGGAATG
GTGTGCTGATAATTGTTCCCGTGATGGTTATCATTATGCTCCTACATATGGAAGTCCTTGGGTTGCTAGTAATAAAAAAT
ATTATACCGAAATTGGGGCCTTAGTACGGGGCGGTTCCTGGGTCTCCTATCCTAGTTATTGCCGTTCTGCGTTTCGCAGC
GGCTCTCTTAGGCGCGACGACCACTTCATCTTTATCGGTTTTCGTGTTGTCTGCGATGGCGGGATAACTCTCTAA

Upstream 100 bases:

>100_bases
TGTTATTTGTGATCTGTTTTTTTAATGACTTTTACTAATAATATACATAGTTATTCTCACATAATTATTATCATTTTTGA
ATTCTGACTTGCCCAAAAAT

Downstream 100 bases:

>100_bases
CCCTTTTCTCTTTCCCCCTTTTGCCCTTTACCCTGTTTTTTTTTCACTAATAACTAATAACTAATAACTGAAATTACCAA
TTAAGAATTAAATGAAAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MNETQQLPISIQPIINYPHSAEVGKTYLMEIDIKQTEDFEKWNYEEEEYPIYFRVDTYCQGDTTPLFKIQIIGEPAVVLH
RFGGTYGPAKFLLTAAQKEMEGEIRVTLVNGWGVPLKRLRLENVAVVADKQDDSIIAGVKVRNNHAIAMGINQYNYLPSL
RYAVKDAEVIKNWFEQKNFSKVDLFTEVISVRLKRFLAEKFEKPFLSAEDNFWFFFSGYGECIEDVDYLIPADSQKDDFR
TTAISVNSLVEKLFSSGAGKVILFLDTNYISGEISFFSGFSFSVKDGQELIVFLSKEANEVEQLQQGSFTYALHEALRSS
EGSLSINQLQKFLSDRGRELNKRNNQQRQILQKFISPKNLGEWVPFPSDFQVFQYTTPTVDGGGKIIKQDTKLTQYFRET
IAQQLELEMVIIPGGNFTMGSPESEEGSYHDERPQNDVTVSPFFMGKYPVTQGQWRAIASQTNLKVNLDLDPEPSYFKEP
YQDIDRWERPVEKVNWYQAVEFCERLSKLTGRNYRLPSEAEWEYACRAGTTTPFYFGETITSELVNYNGNYYGNGPKGEY
RNQTTPVGQFPPNAFGLYDMHGNVWEWCADNCSRDGYHYAPTYGSPWVASNKKYYTEIGALVRGGSWVSYPSYCRSAFRS
GSLRRDDHFIFIGFRVVCDGGITL

Sequences:

>Translated_664_residues
MNETQQLPISIQPIINYPHSAEVGKTYLMEIDIKQTEDFEKWNYEEEEYPIYFRVDTYCQGDTTPLFKIQIIGEPAVVLH
RFGGTYGPAKFLLTAAQKEMEGEIRVTLVNGWGVPLKRLRLENVAVVADKQDDSIIAGVKVRNNHAIAMGINQYNYLPSL
RYAVKDAEVIKNWFEQKNFSKVDLFTEVISVRLKRFLAEKFEKPFLSAEDNFWFFFSGYGECIEDVDYLIPADSQKDDFR
TTAISVNSLVEKLFSSGAGKVILFLDTNYISGEISFFSGFSFSVKDGQELIVFLSKEANEVEQLQQGSFTYALHEALRSS
EGSLSINQLQKFLSDRGRELNKRNNQQRQILQKFISPKNLGEWVPFPSDFQVFQYTTPTVDGGGKIIKQDTKLTQYFRET
IAQQLELEMVIIPGGNFTMGSPESEEGSYHDERPQNDVTVSPFFMGKYPVTQGQWRAIASQTNLKVNLDLDPEPSYFKEP
YQDIDRWERPVEKVNWYQAVEFCERLSKLTGRNYRLPSEAEWEYACRAGTTTPFYFGETITSELVNYNGNYYGNGPKGEY
RNQTTPVGQFPPNAFGLYDMHGNVWEWCADNCSRDGYHYAPTYGSPWVASNKKYYTEIGALVRGGSWVSYPSYCRSAFRS
GSLRRDDHFIFIGFRVVCDGGITL
>Mature_664_residues
MNETQQLPISIQPIINYPHSAEVGKTYLMEIDIKQTEDFEKWNYEEEEYPIYFRVDTYCQGDTTPLFKIQIIGEPAVVLH
RFGGTYGPAKFLLTAAQKEMEGEIRVTLVNGWGVPLKRLRLENVAVVADKQDDSIIAGVKVRNNHAIAMGINQYNYLPSL
RYAVKDAEVIKNWFEQKNFSKVDLFTEVISVRLKRFLAEKFEKPFLSAEDNFWFFFSGYGECIEDVDYLIPADSQKDDFR
TTAISVNSLVEKLFSSGAGKVILFLDTNYISGEISFFSGFSFSVKDGQELIVFLSKEANEVEQLQQGSFTYALHEALRSS
EGSLSINQLQKFLSDRGRELNKRNNQQRQILQKFISPKNLGEWVPFPSDFQVFQYTTPTVDGGGKIIKQDTKLTQYFRET
IAQQLELEMVIIPGGNFTMGSPESEEGSYHDERPQNDVTVSPFFMGKYPVTQGQWRAIASQTNLKVNLDLDPEPSYFKEP
YQDIDRWERPVEKVNWYQAVEFCERLSKLTGRNYRLPSEAEWEYACRAGTTTPFYFGETITSELVNYNGNYYGNGPKGEY
RNQTTPVGQFPPNAFGLYDMHGNVWEWCADNCSRDGYHYAPTYGSPWVASNKKYYTEIGALVRGGSWVSYPSYCRSAFRS
GSLRRDDHFIFIGFRVVCDGGITL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=274, Percent_Identity=30.6569343065693, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38202250, Length=299, Percent_Identity=28.7625418060201, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI194248087, Length=285, Percent_Identity=29.1228070175439, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI257470977, Length=227, Percent_Identity=29.9559471365639, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI194248088, Length=300, Percent_Identity=28.6666666666667, Blast_Score=80, Evalue=9e-15,
Organism=Drosophila melanogaster, GI20130397, Length=293, Percent_Identity=26.6211604095563, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 76087; Mature: 76087

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETQQLPISIQPIINYPHSAEVGKTYLMEIDIKQTEDFEKWNYEEEEYPIYFRVDTYCQ
CCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEEEEEC
GDTTPLFKIQIIGEPAVVLHRFGGTYGPAKFLLTAAQKEMEGEIRVTLVNGWGVPLKRLR
CCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHE
LENVAVVADKQDDSIIAGVKVRNNHAIAMGINQYNYLPSLRYAVKDAEVIKNWFEQKNFS
ECCEEEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KVDLFTEVISVRLKRFLAEKFEKPFLSAEDNFWFFFSGYGECIEDVDYLIPADSQKDDFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCH
TTAISVNSLVEKLFSSGAGKVILFLDTNYISGEISFFSGFSFSVKDGQELIVFLSKEANE
HHEEEHHHHHHHHHHCCCCEEEEEEECCEECCEEEEECCCEEEECCCCEEEEEEECCHHH
VEQLQQGSFTYALHEALRSSEGSLSINQLQKFLSDRGRELNKRNNQQRQILQKFISPKNL
HHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCC
GEWVPFPSDFQVFQYTTPTVDGGGKIIKQDTKLTQYFRETIAQQLELEMVIIPGGNFTMG
CCCCCCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
SPESEEGSYHDERPQNDVTVSPFFMGKYPVTQGQWRAIASQTNLKVNLDLDPEPSYFKEP
CCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCCHHEEECCCCEEEEEECCCCCCHHHCH
YQDIDRWERPVEKVNWYQAVEFCERLSKLTGRNYRLPSEAEWEYACRAGTTTPFYFGETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCHHH
TSELVNYNGNYYGNGPKGEYRNQTTPVGQFPPNAFGLYDMHGNVWEWCADNCSRDGYHYA
HHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEC
PTYGSPWVASNKKYYTEIGALVRGGSWVSYPSYCRSAFRSGSLRRDDHFIFIGFRVVCDG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEECC
GITL
CCCC
>Mature Secondary Structure
MNETQQLPISIQPIINYPHSAEVGKTYLMEIDIKQTEDFEKWNYEEEEYPIYFRVDTYCQ
CCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEEEEEC
GDTTPLFKIQIIGEPAVVLHRFGGTYGPAKFLLTAAQKEMEGEIRVTLVNGWGVPLKRLR
CCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHE
LENVAVVADKQDDSIIAGVKVRNNHAIAMGINQYNYLPSLRYAVKDAEVIKNWFEQKNFS
ECCEEEEEECCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KVDLFTEVISVRLKRFLAEKFEKPFLSAEDNFWFFFSGYGECIEDVDYLIPADSQKDDFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCH
TTAISVNSLVEKLFSSGAGKVILFLDTNYISGEISFFSGFSFSVKDGQELIVFLSKEANE
HHEEEHHHHHHHHHHCCCCEEEEEEECCEECCEEEEECCCEEEECCCCEEEEEEECCHHH
VEQLQQGSFTYALHEALRSSEGSLSINQLQKFLSDRGRELNKRNNQQRQILQKFISPKNL
HHHHHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCC
GEWVPFPSDFQVFQYTTPTVDGGGKIIKQDTKLTQYFRETIAQQLELEMVIIPGGNFTMG
CCCCCCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
SPESEEGSYHDERPQNDVTVSPFFMGKYPVTQGQWRAIASQTNLKVNLDLDPEPSYFKEP
CCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCCHHEEECCCCEEEEEECCCCCCHHHCH
YQDIDRWERPVEKVNWYQAVEFCERLSKLTGRNYRLPSEAEWEYACRAGTTTPFYFGETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCHHH
TSELVNYNGNYYGNGPKGEYRNQTTPVGQFPPNAFGLYDMHGNVWEWCADNCSRDGYHYA
HHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEC
PTYGSPWVASNKKYYTEIGALVRGGSWVSYPSYCRSAFRSGSLRRDDHFIFIGFRVVCDG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEECC
GITL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]