Click here to switch to the map view.

The map label for this gene is iolS [H]

Identifier: 113475784

GI number: 113475784

Start: 3341786

End: 3342769

Strand: Reverse

Name: iolS [H]

Synonym: Tery_2138

Alternate gene names: 113475784

Gene position: 3342769-3341786 (Counterclockwise)

Preceding gene: 113475785

Following gene: 113475783

Centisome position: 43.13

GC content: 41.67

Gene sequence:

>984_bases
ATGAAAAAACGTCAGTTGGGAAATACGGATATCAAAATTAGTGAGGTTGGCTTGGGTACTTGGCAAATGTCAGGGGATGT
GTGGGGGAAAAAAACGGAGGCTGAATATTGTCGGGGGATCGAGGTGGCAATAGAGGCGGGTATTGATTATTTTGATACGG
CTTTAGAATACGGAAATGGCTATTGTGAACAGGTTGTGGGAAAGGTATTACAGAGATATCCATCTGTGGTTATTTCTAGT
AAAATACCTCCTCAATGTGATGAATGGTCACCAAAACCTCAAGATAATATTGATGATTATTTTTCCCCTGCTTGGATAAA
TAAATGTTGCGAGACCACACTTAGAAATTTACGGCGAGAATGCATTGATATTTTATTTCTGCATACTTGGAATGTGGCTT
GGGGCGATCGCACGGAATGGTATGAGGCGATGGTCAAGCTAAAAGAACAGGGAAAAATTAGAGCTATCGGGGTATCAGTG
GGGGACCGGCGTGCTTCTGAAGCGAATAGTCATATCGAAGCAGGACGGATAGATGTGGTAATGGCTGTTTATAATGTTTT
GGAACAGGAGCCAGAATATACTCTCTTGCCGATGGCTAAAAAACATCAGGTGGGGATAATAGCACGCTGTCCGTTTAGTT
CTGGTGCATTGGTGAGTAATTGGACATCTTCTCATAAGTTTCCTGAAGGAGACTGGCGGGGCTTATGGACTTCTCATGAT
TGGGTGGCTAAACAAATGGAAATGGTGGATCATATTAAACCGATCGTCAAAAATACTAACTTACCAATGTGGACTATAGG
CTTAAAATATATTTTGAACAATAAAACGGTGACTTCGGTTATTCCAGGTTCATCTAGCCCTGAACATATTCGCGATAATG
CTTCTGTGACTATGTTGCCTGATCTTTCTGAAGAGGTATTGGGACATTTACAAGAACTTTGGTTAGATGGTAAGGTGCAT
GGAACTTACAATGGTGGGGCTTAA

Upstream 100 bases:

>100_bases
GCTGATCTTTTTTAATAACCGTAAAACTGGTTTAATAATTGCTTTTTGTTCCCTGATAATTTTAGTCGAGCTTTTTTTTC
TTCAAAATTTGCCAGTAAAT

Downstream 100 bases:

>100_bases
TAAAGATTCCTGTTTATGCTTAGAAAACTTCGATAAAACAATTGTAGTAGTTGAATATTAGGCACAGATAGTTCAGTGTT
AAAACTTGGTCAGGGATAAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKKRQLGNTDIKISEVGLGTWQMSGDVWGKKTEAEYCRGIEVAIEAGIDYFDTALEYGNGYCEQVVGKVLQRYPSVVISS
KIPPQCDEWSPKPQDNIDDYFSPAWINKCCETTLRNLRRECIDILFLHTWNVAWGDRTEWYEAMVKLKEQGKIRAIGVSV
GDRRASEANSHIEAGRIDVVMAVYNVLEQEPEYTLLPMAKKHQVGIIARCPFSSGALVSNWTSSHKFPEGDWRGLWTSHD
WVAKQMEMVDHIKPIVKNTNLPMWTIGLKYILNNKTVTSVIPGSSSPEHIRDNASVTMLPDLSEEVLGHLQELWLDGKVH
GTYNGGA

Sequences:

>Translated_327_residues
MKKRQLGNTDIKISEVGLGTWQMSGDVWGKKTEAEYCRGIEVAIEAGIDYFDTALEYGNGYCEQVVGKVLQRYPSVVISS
KIPPQCDEWSPKPQDNIDDYFSPAWINKCCETTLRNLRRECIDILFLHTWNVAWGDRTEWYEAMVKLKEQGKIRAIGVSV
GDRRASEANSHIEAGRIDVVMAVYNVLEQEPEYTLLPMAKKHQVGIIARCPFSSGALVSNWTSSHKFPEGDWRGLWTSHD
WVAKQMEMVDHIKPIVKNTNLPMWTIGLKYILNNKTVTSVIPGSSSPEHIRDNASVTMLPDLSEEVLGHLQELWLDGKVH
GTYNGGA
>Mature_327_residues
MKKRQLGNTDIKISEVGLGTWQMSGDVWGKKTEAEYCRGIEVAIEAGIDYFDTALEYGNGYCEQVVGKVLQRYPSVVISS
KIPPQCDEWSPKPQDNIDDYFSPAWINKCCETTLRNLRRECIDILFLHTWNVAWGDRTEWYEAMVKLKEQGKIRAIGVSV
GDRRASEANSHIEAGRIDVVMAVYNVLEQEPEYTLLPMAKKHQVGIIARCPFSSGALVSNWTSSHKFPEGDWRGLWTSHD
WVAKQMEMVDHIKPIVKNTNLPMWTIGLKYILNNKTVTSVIPGSSSPEHIRDNASVTMLPDLSEEVLGHLQELWLDGKVH
GTYNGGA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=334, Percent_Identity=24.5508982035928, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436962, Length=334, Percent_Identity=24.251497005988, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436966, Length=334, Percent_Identity=24.251497005988, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=27.3615635179153, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788081, Length=289, Percent_Identity=26.2975778546713, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=24.4514106583072, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=230, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36913; Mature: 36913

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRQLGNTDIKISEVGLGTWQMSGDVWGKKTEAEYCRGIEVAIEAGIDYFDTALEYGNG
CCCCCCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHCCC
YCEQVVGKVLQRYPSVVISSKIPPQCDEWSPKPQDNIDDYFSPAWINKCCETTLRNLRRE
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
CIDILFLHTWNVAWGDRTEWYEAMVKLKEQGKIRAIGVSVGDRRASEANSHIEAGRIDVV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCHHHHH
MAVYNVLEQEPEYTLLPMAKKHQVGIIARCPFSSGALVSNWTSSHKFPEGDWRGLWTSHD
HHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
WVAKQMEMVDHIKPIVKNTNLPMWTIGLKYILNNKTVTSVIPGSSSPEHIRDNASVTMLP
HHHHHHHHHHHHHHHHHCCCCCEEEEEHEEEECCCEEEEECCCCCCCHHHHCCCCEEECC
DLSEEVLGHLQELWLDGKVHGTYNGGA
CCHHHHHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MKKRQLGNTDIKISEVGLGTWQMSGDVWGKKTEAEYCRGIEVAIEAGIDYFDTALEYGNG
CCCCCCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHCCC
YCEQVVGKVLQRYPSVVISSKIPPQCDEWSPKPQDNIDDYFSPAWINKCCETTLRNLRRE
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
CIDILFLHTWNVAWGDRTEWYEAMVKLKEQGKIRAIGVSVGDRRASEANSHIEAGRIDVV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCHHHHH
MAVYNVLEQEPEYTLLPMAKKHQVGIIARCPFSSGALVSNWTSSHKFPEGDWRGLWTSHD
HHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
WVAKQMEMVDHIKPIVKNTNLPMWTIGLKYILNNKTVTSVIPGSSSPEHIRDNASVTMLP
HHHHHHHHHHHHHHHHHCCCCCEEEEEHEEEECCCEEEEECCCCCCCHHHHCCCCEEECC
DLSEEVLGHLQELWLDGKVHGTYNGGA
CCHHHHHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]