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The map label for this gene is pkn1 [H]

Identifier: 113475730

GI number: 113475730

Start: 3243857

End: 3245767

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_2077

Alternate gene names: 113475730

Gene position: 3245767-3243857 (Counterclockwise)

Preceding gene: 113475732

Following gene: 113475729

Centisome position: 41.88

GC content: 39.35

Gene sequence:

>1911_bases
ATGACCAATCAAAATATAGCAATTACTATAGGAGTTCAGGAATATGAGTTTTTGACTCCTCTAAAATATGCAGCTAATGA
CGCTAAAAAAATGAGGGATTTTTTGCTCGACGAAGCAGATTTTGATGACGTTTTTTACTTGTCAGATAATTCTCCAAAAA
TTAATGGTGCTTCAACTCGCCCAACTCGTTCCCGCTTAGAATTGGTGTTAGAAGATGAAGTTAAAAAACTATCTCTGAAA
ACTGGTGATAACCTTTGGTTTTTTTTTAGCGGCCATGGTCATAGAGAGAATAATAATATTGATTATTTAATTCCTATTGA
TGGTCATTCAAATGTTGAAAGAAGTGGAATTTCTGTTGACTATATTATTCAACAACTGCAAAAATCTGGAGCAGATAATA
TAGTTCTAATATTGGATGCTTGTAGAAACAAAAGTGATGGGGGAAAAGGGGGAGAAGGACTAGGAAGGCAAACAGAACAA
GAAGCTCGTGAAAAGGGGATAGTAACTATTTTTTCTTGTAGTCCAAATGAACGTTCTTGGGAATTAGAAGAGTTGCAACA
GGGAGTTTTTACTTATGCGTTATTAGAGGGGTTAGGTAGTAAGGGTCAAAAAGCAACTGCAGAAAGACTGAATGAATATC
TGAAGTATCGGGTGCAAGAGCTAGCTCAAAAGGAAGGAAAACGACAGACCCCTCGTATTATTGCTGACCCTATTGAAAAG
TCTCATTTAATTTTAATGCCGAAGTATGCAACAAAAACTGATGTTTCTACTCTGAAAATTGACGCTTACAGAGCTCAAAC
AAATGGAGATTTTAATTGGGCAGAACAACTATGGATAAGAGTTTTAGAGGTAGGTTTGGATCTTGAAGCAGTTAAGGCTC
TGCAGAAAATTGCTGTTGATCGGTTTAGATCTCAGTTGGTTTCCACCCCACAGTTAGATCTAGGTTATTTTCAGAATTTA
CCGGTTTCAGAAACTCAACAACCAAGATCAACAGAAGTATTAGAAGGTTCAAATATTCAAACTTCACTACAGTCACAACG
GAAGTTAGAACCAAACTCACAAATAAAAACAAAGTCACAGCCAAAAATTACTATTCATACATTTGCGACTCCTAAAGTTA
ACAGGAAAGGAGAAATAATAAGCCGCTCTGAAGGTGAAGCAGAAGTAATGATAGAAAATTTAGGTAATGGAGTTACTCTG
GAAATGGTAAAAATACCCGGTGGTAGTTTTCTGATGGGGTCTCCAGAGACGGAAGCACAGAGAAGTGATAATGAAGGTCC
GCAACATCATGTAGATGTGCCAGAATTTTGGATGGGAAAGTATGTCGTTACTCAACAACAGTGGCAAGCAATAATGGGAA
ATGATCCTTCGAAATTTAAAGGAAAAAATCGCCCTGTGGAAAGAGTAAGTTGGAATAACGCTACAGAATTTTGTCAAAAG
CTCTCTAAGAAAACAGGAAGAGACTATAGACTACCGAGTGAAGCAGAATGGGAATATGCCTGTCGTGCTGGGACAACTAC
ACCTTTTTATTTTGGAGAAACTATCACAGGAGAATTAGCTAATTATAGAGCTTCAGAGACTTATGCTGATGAACCAAAAG
GAGAATATAGAGAACAAACAACTCCTGTAGGTGAGTTTCCACCTAATGCTTTTGGTCTATATGACATGCATGGGAATGTC
TGGGAGTGGTGTCAGGATGTTGTGCATAGTAATTATGATGGAGCACCTGTTGATGGAAGTGCTTGGGTAAATGGAGGCGA
TAGTAGCGGTAGAGTGCTTCGTGGCGGCTCCTGGCTCAACTATCCTGGGTGGTGTCGCTCTGCGAGCCGCGGCTACTATG
TCTCGGTCGTGGTGGTCAGCTCCAATTTTGGTTTTCGTCTTGTGAGTTTCCCCCCCAGGACTCCTGAATAG

Upstream 100 bases:

>100_bases
TAAGTTAAACCTGAGTTAGCGATCGCTAACCTGGTTCAACAGAATTATCTGTCAGGAAAAAGTGCTACTAAGTTGAAATT
TAAATCACAGCAGAGAAACG

Downstream 100 bases:

>100_bases
CCCTTTGCTCTTTTGCCCTTTTGCCCTATTTAGCCTCGCCTTTGGCGAGTCGAAATTTTTTGCCATCATGCAATACTACA
ATGTATTACGCTGAAAGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTNQNIAITIGVQEYEFLTPLKYAANDAKKMRDFLLDEADFDDVFYLSDNSPKINGASTRPTRSRLELVLEDEVKKLSLK
TGDNLWFFFSGHGHRENNNIDYLIPIDGHSNVERSGISVDYIIQQLQKSGADNIVLILDACRNKSDGGKGGEGLGRQTEQ
EAREKGIVTIFSCSPNERSWELEELQQGVFTYALLEGLGSKGQKATAERLNEYLKYRVQELAQKEGKRQTPRIIADPIEK
SHLILMPKYATKTDVSTLKIDAYRAQTNGDFNWAEQLWIRVLEVGLDLEAVKALQKIAVDRFRSQLVSTPQLDLGYFQNL
PVSETQQPRSTEVLEGSNIQTSLQSQRKLEPNSQIKTKSQPKITIHTFATPKVNRKGEIISRSEGEAEVMIENLGNGVTL
EMVKIPGGSFLMGSPETEAQRSDNEGPQHHVDVPEFWMGKYVVTQQQWQAIMGNDPSKFKGKNRPVERVSWNNATEFCQK
LSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITGELANYRASETYADEPKGEYREQTTPVGEFPPNAFGLYDMHGNV
WEWCQDVVHSNYDGAPVDGSAWVNGGDSSGRVLRGGSWLNYPGWCRSASRGYYVSVVVVSSNFGFRLVSFPPRTPE

Sequences:

>Translated_636_residues
MTNQNIAITIGVQEYEFLTPLKYAANDAKKMRDFLLDEADFDDVFYLSDNSPKINGASTRPTRSRLELVLEDEVKKLSLK
TGDNLWFFFSGHGHRENNNIDYLIPIDGHSNVERSGISVDYIIQQLQKSGADNIVLILDACRNKSDGGKGGEGLGRQTEQ
EAREKGIVTIFSCSPNERSWELEELQQGVFTYALLEGLGSKGQKATAERLNEYLKYRVQELAQKEGKRQTPRIIADPIEK
SHLILMPKYATKTDVSTLKIDAYRAQTNGDFNWAEQLWIRVLEVGLDLEAVKALQKIAVDRFRSQLVSTPQLDLGYFQNL
PVSETQQPRSTEVLEGSNIQTSLQSQRKLEPNSQIKTKSQPKITIHTFATPKVNRKGEIISRSEGEAEVMIENLGNGVTL
EMVKIPGGSFLMGSPETEAQRSDNEGPQHHVDVPEFWMGKYVVTQQQWQAIMGNDPSKFKGKNRPVERVSWNNATEFCQK
LSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITGELANYRASETYADEPKGEYREQTTPVGEFPPNAFGLYDMHGNV
WEWCQDVVHSNYDGAPVDGSAWVNGGDSSGRVLRGGSWLNYPGWCRSASRGYYVSVVVVSSNFGFRLVSFPPRTPE
>Mature_635_residues
TNQNIAITIGVQEYEFLTPLKYAANDAKKMRDFLLDEADFDDVFYLSDNSPKINGASTRPTRSRLELVLEDEVKKLSLKT
GDNLWFFFSGHGHRENNNIDYLIPIDGHSNVERSGISVDYIIQQLQKSGADNIVLILDACRNKSDGGKGGEGLGRQTEQE
AREKGIVTIFSCSPNERSWELEELQQGVFTYALLEGLGSKGQKATAERLNEYLKYRVQELAQKEGKRQTPRIIADPIEKS
HLILMPKYATKTDVSTLKIDAYRAQTNGDFNWAEQLWIRVLEVGLDLEAVKALQKIAVDRFRSQLVSTPQLDLGYFQNLP
VSETQQPRSTEVLEGSNIQTSLQSQRKLEPNSQIKTKSQPKITIHTFATPKVNRKGEIISRSEGEAEVMIENLGNGVTLE
MVKIPGGSFLMGSPETEAQRSDNEGPQHHVDVPEFWMGKYVVTQQQWQAIMGNDPSKFKGKNRPVERVSWNNATEFCQKL
SKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITGELANYRASETYADEPKGEYREQTTPVGEFPPNAFGLYDMHGNVW
EWCQDVVHSNYDGAPVDGSAWVNGGDSSGRVLRGGSWLNYPGWCRSASRGYYVSVVVVSSNFGFRLVSFPPRTPE

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=277, Percent_Identity=30.3249097472924, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI38202250, Length=302, Percent_Identity=27.4834437086093, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI194248087, Length=293, Percent_Identity=28.6689419795222, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI257470977, Length=228, Percent_Identity=26.7543859649123, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI194248088, Length=185, Percent_Identity=32.972972972973, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI226437577, Length=185, Percent_Identity=32.972972972973, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20130397, Length=196, Percent_Identity=31.6326530612245, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 71558; Mature: 71427

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQNIAITIGVQEYEFLTPLKYAANDAKKMRDFLLDEADFDDVFYLSDNSPKINGASTR
CCCCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
PTRSRLELVLEDEVKKLSLKTGDNLWFFFSGHGHRENNNIDYLIPIDGHSNVERSGISVD
CCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHCCCCHH
YIIQQLQKSGADNIVLILDACRNKSDGGKGGEGLGRQTEQEAREKGIVTIFSCSPNERSW
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCC
ELEELQQGVFTYALLEGLGSKGQKATAERLNEYLKYRVQELAQKEGKRQTPRIIADPIEK
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
SHLILMPKYATKTDVSTLKIDAYRAQTNGDFNWAEQLWIRVLEVGLDLEAVKALQKIAVD
CEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RFRSQLVSTPQLDLGYFQNLPVSETQQPRSTEVLEGSNIQTSLQSQRKLEPNSQIKTKSQ
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCCCCCCC
PKITIHTFATPKVNRKGEIISRSEGEAEVMIENLGNGVTLEMVKIPGGSFLMGSPETEAQ
CCEEEEEECCCCCCCCCCEEECCCCCCEEHHHHCCCCEEEEEEEECCCCEEECCCCCHHH
RSDNEGPQHHVDVPEFWMGKYVVTQQQWQAIMGNDPSKFKGKNRPVERVSWNNATEFCQK
CCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHCCCCHHCCCCCCCHHHCCCCCHHHHHHH
LSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITGELANYRASETYADEPKGEYREQT
HHHHCCCCCCCCCCCCCHHHCCCCCCCCEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHC
TPVGEFPPNAFGLYDMHGNVWEWCQDVVHSNYDGAPVDGSAWVNGGDSSGRVLRGGSWLN
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEECCCCCC
YPGWCRSASRGYYVSVVVVSSNFGFRLVSFPPRTPE
CCHHHCCCCCCEEEEEEEEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
TNQNIAITIGVQEYEFLTPLKYAANDAKKMRDFLLDEADFDDVFYLSDNSPKINGASTR
CCCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
PTRSRLELVLEDEVKKLSLKTGDNLWFFFSGHGHRENNNIDYLIPIDGHSNVERSGISVD
CCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHCCCCHH
YIIQQLQKSGADNIVLILDACRNKSDGGKGGEGLGRQTEQEAREKGIVTIFSCSPNERSW
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCC
ELEELQQGVFTYALLEGLGSKGQKATAERLNEYLKYRVQELAQKEGKRQTPRIIADPIEK
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
SHLILMPKYATKTDVSTLKIDAYRAQTNGDFNWAEQLWIRVLEVGLDLEAVKALQKIAVD
CEEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RFRSQLVSTPQLDLGYFQNLPVSETQQPRSTEVLEGSNIQTSLQSQRKLEPNSQIKTKSQ
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCCCCCCC
PKITIHTFATPKVNRKGEIISRSEGEAEVMIENLGNGVTLEMVKIPGGSFLMGSPETEAQ
CCEEEEEECCCCCCCCCCEEECCCCCCEEHHHHCCCCEEEEEEEECCCCEEECCCCCHHH
RSDNEGPQHHVDVPEFWMGKYVVTQQQWQAIMGNDPSKFKGKNRPVERVSWNNATEFCQK
CCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHCCCCHHCCCCCCCHHHCCCCCHHHHHHH
LSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITGELANYRASETYADEPKGEYREQT
HHHHCCCCCCCCCCCCCHHHCCCCCCCCEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHC
TPVGEFPPNAFGLYDMHGNVWEWCQDVVHSNYDGAPVDGSAWVNGGDSSGRVLRGGSWLN
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEECCCCCC
YPGWCRSASRGYYVSVVVVSSNFGFRLVSFPPRTPE
CCHHHCCCCCCEEEEEEEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]