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The map label for this gene is pkn1 [H]

Identifier: 113475666

GI number: 113475666

Start: 3124502

End: 3126070

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_2006

Alternate gene names: 113475666

Gene position: 3126070-3124502 (Counterclockwise)

Preceding gene: 113475669

Following gene: 113475655

Centisome position: 40.34

GC content: 36.2

Gene sequence:

>1569_bases
GTGGTTAATTTAAAAAAGTTGGAAGATTCTATTGTTTTAATTGCAAGTGCTAAAGATAATAGAAAAAATGTTATTGGTAC
TGGATTTATATTTCATAAGGAACAGAATTGTACTTATCTACTTACTTGTGCTCATGTTGTTGAGGATGTTGGTGGGGCAG
ACAACATAAAGGTAAATAATATTCCGGCGGAAGTTATAAAGATAGGAGATATTCAGGGTTTTGATTTAGCTGTTTTAAAG
GTGAATGAAAGTTTTTCAGCTCCATCTTTAAGTTTAATGATTTTATATGGAGAGGAAGAAAAAAATTTGCTTGTGAAAAT
TCCTGGTTATTATCTTTGGGGTCAAAATAATGCACTTTGTCGTCAAACAATAAAAGGAAGAATGACAGTAGAGGTTGATG
GAGAAAGGGCATTTCAATTAATAGAAAATATGCCAGAAGATGTGGCGGTTGAAAAGTTAGAGATAGAAAAAGGAAGTCTC
CGTTCAGGTTATAGTGGTTCTCCTGTTATTGATATTAATACAGGACTAGTTATCGGTCTAGTTACTCATAAAATTGATGT
TGATGGAGTAGGAATGTTTGGTAGAGCAATATCAATAGAGGCTTTAGAAAAAATTTGGTTTGAAATAACTGATGAAGTCT
TTAAAAAAATTAAACGAGAATCAAAAACAATAGAAGTTTTAACTAGTACAAATATTGAAGATAATTTAGAAAGTAAAGTT
ACATTATCAAAAGAACTAGACAAGGGAGAATTGTTTACTTTTGCAGTTGTAAGTGTTAATAATTTTGGCAGTATTGTTAA
TCGTAGTCAAGGGGGTGCTAGACAGAAAATAGAAAATTTAGGTAATGGAATTAAATTGGAAATGGTTTATATTCCTGGGG
GTACTTTTACTATGGGTTCTCCTGAAAGTGAAGTGGATAGCAATAATAATGAACGGCCCCAACATGATGTAACTGTCCCT
AACTTTTTTATGGGCAAATATCCAGTTACTCAAGGACAGTGGAAAGCGATCGCCTCCTGCGCAGACTTGAAAGTAAAATT
AGACCTAGAGCTAGAACCATCTTATTTTAAAGAACCATACCGAAATATAGATAGATGGCAGAGACCAGTTGAGGAGGTTA
TTTGGTACCAAGCTATAGAGTTTTGCCAAAGGCTATCGAAATTAACAGGAAAGAATTATAGACTGCCCAGTGAAGCAGAA
TGGGAATATGCTTGCCGTGCAGGAACAACTACACCTTTCTATTTTGGGGAAACTATAACGCCTGAGTTAGTTAACTATAA
TGACAAATATGTTTATGGTAGTGCACCAAAAGGAGAATATAGAGAACAAACAACTCCCGTAGGCCAATTTCCGGCTAATG
CTTTTGGGTTATACGATATGCACGGAAATGTGTGGGAGTGGTGTGCTGATCAATGGCATCGTAACTATAATGGTGCTCCT
ACAGATGGCAGTGTTTGGCTAGATGGAGATAAAGAGATAACATGTGTGCGGGGCGGTTCCTGGGACGACTTTCCTAATTC
TTGCCGTTCTGCGTTTCGCTTGAACTATGTTAGGCGCGACTACCGCTAG

Upstream 100 bases:

>100_bases
CTAAAACATTTAAAAATTTAACTCCTACTTTTGGTAGGTTGGTTTGGCTCTGGCTTCAAGCCTTTAGTATAAAGTTAAGA
AGGAACTAATTAATTAAAAA

Downstream 100 bases:

>100_bases
GGCATTATCGGTTTTCGTGTAGTCTGCGATGGCGGGAGAACTCTCTAACCCTTTTTTCTTTTCCCCTTTTACCCTTTGCC
CTGTTTTTCTTTTTCCTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MVNLKKLEDSIVLIASAKDNRKNVIGTGFIFHKEQNCTYLLTCAHVVEDVGGADNIKVNNIPAEVIKIGDIQGFDLAVLK
VNESFSAPSLSLMILYGEEEKNLLVKIPGYYLWGQNNALCRQTIKGRMTVEVDGERAFQLIENMPEDVAVEKLEIEKGSL
RSGYSGSPVIDINTGLVIGLVTHKIDVDGVGMFGRAISIEALEKIWFEITDEVFKKIKRESKTIEVLTSTNIEDNLESKV
TLSKELDKGELFTFAVVSVNNFGSIVNRSQGGARQKIENLGNGIKLEMVYIPGGTFTMGSPESEVDSNNNERPQHDVTVP
NFFMGKYPVTQGQWKAIASCADLKVKLDLELEPSYFKEPYRNIDRWQRPVEEVIWYQAIEFCQRLSKLTGKNYRLPSEAE
WEYACRAGTTTPFYFGETITPELVNYNDKYVYGSAPKGEYREQTTPVGQFPANAFGLYDMHGNVWEWCADQWHRNYNGAP
TDGSVWLDGDKEITCVRGGSWDDFPNSCRSAFRLNYVRRDYR

Sequences:

>Translated_522_residues
MVNLKKLEDSIVLIASAKDNRKNVIGTGFIFHKEQNCTYLLTCAHVVEDVGGADNIKVNNIPAEVIKIGDIQGFDLAVLK
VNESFSAPSLSLMILYGEEEKNLLVKIPGYYLWGQNNALCRQTIKGRMTVEVDGERAFQLIENMPEDVAVEKLEIEKGSL
RSGYSGSPVIDINTGLVIGLVTHKIDVDGVGMFGRAISIEALEKIWFEITDEVFKKIKRESKTIEVLTSTNIEDNLESKV
TLSKELDKGELFTFAVVSVNNFGSIVNRSQGGARQKIENLGNGIKLEMVYIPGGTFTMGSPESEVDSNNNERPQHDVTVP
NFFMGKYPVTQGQWKAIASCADLKVKLDLELEPSYFKEPYRNIDRWQRPVEEVIWYQAIEFCQRLSKLTGKNYRLPSEAE
WEYACRAGTTTPFYFGETITPELVNYNDKYVYGSAPKGEYREQTTPVGQFPANAFGLYDMHGNVWEWCADQWHRNYNGAP
TDGSVWLDGDKEITCVRGGSWDDFPNSCRSAFRLNYVRRDYR
>Mature_522_residues
MVNLKKLEDSIVLIASAKDNRKNVIGTGFIFHKEQNCTYLLTCAHVVEDVGGADNIKVNNIPAEVIKIGDIQGFDLAVLK
VNESFSAPSLSLMILYGEEEKNLLVKIPGYYLWGQNNALCRQTIKGRMTVEVDGERAFQLIENMPEDVAVEKLEIEKGSL
RSGYSGSPVIDINTGLVIGLVTHKIDVDGVGMFGRAISIEALEKIWFEITDEVFKKIKRESKTIEVLTSTNIEDNLESKV
TLSKELDKGELFTFAVVSVNNFGSIVNRSQGGARQKIENLGNGIKLEMVYIPGGTFTMGSPESEVDSNNNERPQHDVTVP
NFFMGKYPVTQGQWKAIASCADLKVKLDLELEPSYFKEPYRNIDRWQRPVEEVIWYQAIEFCQRLSKLTGKNYRLPSEAE
WEYACRAGTTTPFYFGETITPELVNYNDKYVYGSAPKGEYREQTTPVGQFPANAFGLYDMHGNVWEWCADQWHRNYNGAP
TDGSVWLDGDKEITCVRGGSWDDFPNSCRSAFRLNYVRRDYR

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=205, Percent_Identity=29.7560975609756, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI194248087, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI194248088, Length=264, Percent_Identity=28.030303030303, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38202250, Length=230, Percent_Identity=26.5217391304348, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI257470977, Length=230, Percent_Identity=26.5217391304348, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226437577, Length=165, Percent_Identity=32.7272727272727, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130397, Length=229, Percent_Identity=29.2576419213974, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 58910; Mature: 58910

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLKKLEDSIVLIASAKDNRKNVIGTGFIFHKEQNCTYLLTCAHVVEDVGGADNIKVNN
CCCHHCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHHCCCCCCEEECC
IPAEVIKIGDIQGFDLAVLKVNESFSAPSLSLMILYGEEEKNLLVKIPGYYLWGQNNALC
CCCEEEEECCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEECCEEEECCCCHHH
RQTIKGRMTVEVDGERAFQLIENMPEDVAVEKLEIEKGSLRSGYSGSPVIDINTGLVIGL
HHHHCCCEEEEECHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCEEEECCCEEEEE
VTHKIDVDGVGMFGRAISIEALEKIWFEITDEVFKKIKRESKTIEVLTSTNIEDNLESKV
EEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEE
TLSKELDKGELFTFAVVSVNNFGSIVNRSQGGARQKIENLGNGIKLEMVYIPGGTFTMGS
EEHHCCCCCCEEEEEEEEECCCHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCEEECCC
PESEVDSNNNERPQHDVTVPNFFMGKYPVTQGQWKAIASCADLKVKLDLELEPSYFKEPY
CCHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHEECEEEEEEEEECCHHHHHHH
RNIDRWQRPVEEVIWYQAIEFCQRLSKLTGKNYRLPSEAEWEYACRAGTTTPFYFGETIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEECCCCCC
PELVNYNDKYVYGSAPKGEYREQTTPVGQFPANAFGLYDMHGNVWEWCADQWHRNYNGAP
HHHHCCCCCEEECCCCCCCCHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
TDGSVWLDGDKEITCVRGGSWDDFPNSCRSAFRLNYVRRDYR
CCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNLKKLEDSIVLIASAKDNRKNVIGTGFIFHKEQNCTYLLTCAHVVEDVGGADNIKVNN
CCCHHCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHHCCCCCCEEECC
IPAEVIKIGDIQGFDLAVLKVNESFSAPSLSLMILYGEEEKNLLVKIPGYYLWGQNNALC
CCCEEEEECCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEECCEEEECCCCHHH
RQTIKGRMTVEVDGERAFQLIENMPEDVAVEKLEIEKGSLRSGYSGSPVIDINTGLVIGL
HHHHCCCEEEEECHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCEEEECCCEEEEE
VTHKIDVDGVGMFGRAISIEALEKIWFEITDEVFKKIKRESKTIEVLTSTNIEDNLESKV
EEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEE
TLSKELDKGELFTFAVVSVNNFGSIVNRSQGGARQKIENLGNGIKLEMVYIPGGTFTMGS
EEHHCCCCCCEEEEEEEEECCCHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCEEECCC
PESEVDSNNNERPQHDVTVPNFFMGKYPVTQGQWKAIASCADLKVKLDLELEPSYFKEPY
CCHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHEECEEEEEEEEECCHHHHHHH
RNIDRWQRPVEEVIWYQAIEFCQRLSKLTGKNYRLPSEAEWEYACRAGTTTPFYFGETIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEECCCCCC
PELVNYNDKYVYGSAPKGEYREQTTPVGQFPANAFGLYDMHGNVWEWCADQWHRNYNGAP
HHHHCCCCCEEECCCCCCCCHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
TDGSVWLDGDKEITCVRGGSWDDFPNSCRSAFRLNYVRRDYR
CCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]