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The map label for this gene is prpC [H]

Identifier: 113475615

GI number: 113475615

Start: 3023400

End: 3025337

Strand: Reverse

Name: prpC [H]

Synonym: Tery_1950

Alternate gene names: 113475615

Gene position: 3025337-3023400 (Counterclockwise)

Preceding gene: 113475618

Following gene: 113475614

Centisome position: 39.04

GC content: 39.06

Gene sequence:

>1938_bases
ATGATTAATTCTGCGCCAATAATTCATTGTCCAAATATTAATTGTTCTAGTGTTTCTCACTCTTGGGATCAGGAAGAGTG
TGAAGCTTGCCAAACTAAATTAATCTATCGCTATTTATGGGCAGTTGCTCCAAAAGTCGAGATTTCTGTAGGGGAGTTAT
TGGGCGATCGCTACTATGTTGTAGCTCCACAAGTTTGGCTAGATACGAAGCCTGGTGAACCTCCATTTATGCACGAGGAA
TTTCCAGATTATATTATGCCTTATCTACGCTTATATCCTGAGAGGCTTCATACACCAGATGTATATGGTTTTTATCAGTA
TGGAGAAGAAACATATCCTACAGATATTCTATTATTAGATAATGTTCCTCTGGACTCTAAAGGTAATTTGCTTCCTAGTC
TTGTAGAAGCTTGGCCCACAGCAAGTCCTGTACGTCAGGTCTACTGGTTGTGGCAAATGATGCAATTATGGAAACCTCTA
TCAGAAGAGCGTGTAGCTTTTAGTTTATTGACCAATAATTTACGGGTGGAAGATTGGCGATTACGATTGTTAGAGTTAAA
CCTAGAAACCCGTAAAACTAAACTTAGAGATTTTAAGATTTTTTGGTCAAATTTGCTTCCGACAGCTCATCCTAACGTTC
AACAACCATTGACAGAGATTTGTCATATGATTAGTGATATTGGGGAATCTTTAGAGGCGATCGCTCCGAAATTAAACCAA
CTACTATTAGAACAGGCAGCCAAATTACCATTAAAATCCGATATCATGGGGGCGACGGATACAGGTCCCGTGCGTATGCA
TAATGAAGACTGTTGTTATCCTACAGAAGAGGACTTAAATAGTAATCAACTAGTGCCCAATTTAGCAATAATTTGTGATG
GAGTGGGTGGCCATGATGGCGGAGAGGTAGCTAGTCAACTTGCAGTACAATCAATAAAAAAATTAGTTCAAAATTTATTA
ATAGAGGTAGAGCAACAAGAGGAGTTAACATCCCCAAACTTAGTCAATAAACAACTAGAGGAAATTATTCGGGTAGTCAA
TAATATGATTGCTACGGAGAATGATGAACAAGGAAGAGAGTCTCGACAGCGCATGGGTACAACACTAGCCATGGCATTAC
AGTTACCCCAACAGGTGAAACCTTCCCCAGAATCTAGTCCAAATAATGCCCATGAGTTATATATAGTTCATGTGGGAGAT
AGTCGTGCTTATTGGTTAAGTAGAAATACTTGTCAGTTGTTGACTGTGGATGATAATGTTGCTTCTAGAGAAGTTGGTTT
GGGTCATTGTTTGTATTGGCAGGGTTTAAAACGTCGTGATGGTGGTGCCTTGACTCAGGCTTTGGGTACAAGAGATGGGG
AGTTTATTTATCCTACTATTCAAAGATTTTTGATCGAACAAGAGGGGATATTACTTTTATGTTCCGATGGCCTGAGTGAT
AATAATTGGGTTGAGAATTCTTGGGCTGAATATGCTTCTAAAGTTTTCCAGGGTGAAATTTCTCTAAAACAGGGGGTAGA
GTCTTTAATTGAGCTGGCGAATCATAAAAATGGTCATGATAATACTTCGGTGGTGCTTGTCCACTATCGTCTTTCTCCAG
AGAAGTTAATCTTATCTAATATTCCTACAGTAACAACTCCAGAAAAGGAAATTTTAATGACAGAATTGTCTGAGGCTTCT
AAAGAGCTTCTTTACAATAATGATGAAGAAGTATCAGAAGCTGAGTCTGAATTTCAGTTGGAACCTGTCCAAAATTTTTT
CTGGTTAAAACCCTGGATGTGTATGATGGGTGTCTTATTTATCTTGTTGGTGGGGGCAATTATATCGGTATGGCGCAATT
GGGAAAATTTTCAGTCAACTCCTAGGGATAGTCCTGCACCTTGGGAGAGTCCTATGAGACCTGAGCCTTCAGAAACTAGA
ATTTCTCCTAGTTCTTAA

Upstream 100 bases:

>100_bases
ACCAACACGAAAATTATCAAATTAATTTTTAAATAGTAAAACTTTTGACTTCATAAAGAGTAAATTGTATTACTTTTGAT
TTTTGACTTAATTCCCAACT

Downstream 100 bases:

>100_bases
TCCTTATTTGAGGGTTTTTAACAGTAAGTTTTATGCAAAAATAAGAAAATTGTTAAATAAGCTTGTAATTTCTTCTTGGA
GTTGCATAAAAATTTATCAG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYVVAPQVWLDTKPGEPPFMHEE
FPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLDNVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPL
SEERVAFSLLTNNLRVEDWRLRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQ
LLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDGGEVASQLAVQSIKKLVQNLL
IEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRESRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGD
SRAYWLSRNTCQLLTVDDNVASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSD
NNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSNIPTVTTPEKEILMTELSEAS
KELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLFILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETR
ISPSS

Sequences:

>Translated_645_residues
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYVVAPQVWLDTKPGEPPFMHEE
FPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLDNVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPL
SEERVAFSLLTNNLRVEDWRLRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQ
LLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDGGEVASQLAVQSIKKLVQNLL
IEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRESRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGD
SRAYWLSRNTCQLLTVDDNVASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSD
NNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSNIPTVTTPEKEILMTELSEAS
KELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLFILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETR
ISPSS
>Mature_645_residues
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYVVAPQVWLDTKPGEPPFMHEE
FPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLDNVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPL
SEERVAFSLLTNNLRVEDWRLRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQ
LLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDGGEVASQLAVQSIKKLVQNLL
IEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRESRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGD
SRAYWLSRNTCQLLTVDDNVASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSD
NNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSNIPTVTTPEKEILMTELSEAS
KELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLFILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETR
ISPSS

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 73442; Mature: 73442

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCEEE
VAPQVWLDTKPGEPPFMHEEFPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLD
EECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEC
NVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPLSEERVAFSLLTNNLRVEDWR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEHEE
LRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQ
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDG
HHHHHHHCCCCHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
GEVASQLAVQSIKKLVQNLLIEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGDSRAYWLSRNTCQLLTVDDNV
HHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCEEEEEECCCC
ASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSD
CHHCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCC
NNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSN
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHC
IPTVTTPEKEILMTELSEASKELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETRISPSS
HHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCEEE
VAPQVWLDTKPGEPPFMHEEFPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLD
EECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEC
NVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPLSEERVAFSLLTNNLRVEDWR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEHEE
LRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQ
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDG
HHHHHHHCCCCHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
GEVASQLAVQSIKKLVQNLLIEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGDSRAYWLSRNTCQLLTVDDNV
HHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCEEEEEECCCC
ASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSD
CHHCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCC
NNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSN
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHC
IPTVTTPEKEILMTELSEASKELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETRISPSS
HHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]