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The map label for this gene is argG

Identifier: 113474696

GI number: 113474696

Start: 1401369

End: 1402571

Strand: Reverse

Name: argG

Synonym: Tery_0882

Alternate gene names: 113474696

Gene position: 1402571-1401369 (Counterclockwise)

Preceding gene: 113474708

Following gene: 113474694

Centisome position: 18.1

GC content: 42.23

Gene sequence:

>1203_bases
ATGAGTCGTGCTACTAAAGTTGTGCTAGCTTATTCTGGAGGAGTAGATACTTCTGTTTGTATCCCTTATCTGAAAAATGA
ATGGGGAGTAAAAGAAGTAATTACCCTAGCAGCAGATTTAGGTCAAGGAGATGAATTAGAAGGAGTTCGGAAAAAAGCAT
TAGATTCTGGGGCAGTAGAATCTCTAGTCATAGATGTTATTGAACCTCTAATTAAAGAATATGCTTTTCCTGCTATTCAA
GCAAATGCTCTATATGAAAATCGCTACCCTCTAGCAACAGCATTAGCTCGACCTCTAATTGCCAAAATATTAGTAGAGGC
AGCAGAAAAATATGGTGCTGATGCTATTGCCCACGGTTGTACAGGAAAAGGTAATGACCAGGTAAGGTTTGATGTTGCTA
TTGCCGCACTAAATCCTCAAATTAAGATTCTTGCACCTGCGCGGGAGTGGGGAATGAGTCGGGAGGAGACTATTGCTTAT
GGTGAAGAGTATGGCATTCCGGCTCCTGTGAAAAAATCTTCCCCTTATAGTATAGATAAGAATTTATTGGGGATGGCGAT
CGAAGCTGGTGAGTTGGAAGATCCTTGGGTGGAGCCCCCAGAAGAAGTTTATGGGATGACTAAGGCGATCGCTGACACTC
CCAACGAACCAGAATATATAGAGATTGGTTTTGAGCGGGGTATTCCTGTTAGTCTTAATGGTCAAGAAATGGGTGGTATT
GAGTTGATAACTAAACTTAATCAGATAGCAGGAAACCATGGCATTGGTCGAATTGACATGATTGAAAACCGTCTGGTGGG
GATTAAGTCGAGAGAAATTTATGAGTCTCCGGCAATGTGGGTGTTAATTCAAGGACACCGAGATTTAGAGAGTTTGACTT
TAACTGCTGATGTAACTCGTTATAAGCGGGGTATTGAGGAGACTTATAGTCAGTTGGTTTATAACGGTTTGTGGTTTAGT
CCGTTGAAGGGTGCATTGGATGCTTTTATTCAGCAGACCCAGGAAAGGGTGACTGGTGTTGTGCGGGTCAAGTTGTTTAA
GGGTAATGCAATGGTTGTTGGTCGTAAGTCTGATAATTCTTTGTATAGTTTTGACTTAGCGACTTATGGTGCGGAGGATG
AGTTTGACCATAAAGCGGCGGAAGGATTTATTTATGTTTGGGGTTTGCCGACTCGTGTTTGGTCAGAGAAACTCCGGGGT
TAA

Upstream 100 bases:

>100_bases
GGTTTTTATTGGCATAAAAAAAGTTTATACTTTAATTAACAATAAAGCTACAGATTTAGTTTAATAATAATAACTCAGTT
GTTAATTTTTGAATAAAAAT

Downstream 100 bases:

>100_bases
TAGCTGGGTGATTTTTTAAGTTTGATTAGTTGTTCCTGTAGGGATGAAATATTAGTCTCTACAGGAATAAGTATAATTAC
TAATTTATTGGCATCTTCTA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVESLVIDVIEPLIKEYAFPAIQ
ANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGCTGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAY
GEEYGIPAPVKKSSPYSIDKNLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGI
ELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTRYKRGIEETYSQLVYNGLWFS
PLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNSLYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG

Sequences:

>Translated_400_residues
MSRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVESLVIDVIEPLIKEYAFPAIQ
ANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGCTGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAY
GEEYGIPAPVKKSSPYSIDKNLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGI
ELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTRYKRGIEETYSQLVYNGLWFS
PLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNSLYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG
>Mature_399_residues
SRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVESLVIDVIEPLIKEYAFPAIQA
NALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGCTGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAYG
EEYGIPAPVKKSSPYSIDKNLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGIE
LITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTRYKRGIEETYSQLVYNGLWFSP
LKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNSLYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI53759107, Length=402, Percent_Identity=42.2885572139304, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI16950633, Length=402, Percent_Identity=42.2885572139304, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1789563, Length=359, Percent_Identity=29.2479108635098, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324514, Length=412, Percent_Identity=36.1650485436893, Blast_Score=273, Evalue=3e-74,
Organism=Drosophila melanogaster, GI21358151, Length=400, Percent_Identity=39.25, Blast_Score=283, Evalue=2e-76,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ASSY_TRIEI (Q117P0)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720757.1
- ProteinModelPortal:   Q117P0
- SMR:   Q117P0
- STRING:   Q117P0
- GeneID:   4245545
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0882
- NMPDR:   fig|203124.1.peg.3805
- eggNOG:   COG0137
- HOGENOM:   HBG335267
- OMA:   KRVILAY
- PhylomeDB:   Q117P0
- ProtClustDB:   PRK00509
- BioCyc:   TERY203124:TERY_0882-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00005
- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- TIGRFAMs:   TIGR00032

Pfam domain/function: PF00764 Arginosuc_synth

EC number: =6.3.4.5

Molecular weight: Translated: 44033; Mature: 43902

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1; PS00565 ARGININOSUCCIN_SYN_2

Important sites: BINDING 38-38 BINDING 89-89 BINDING 119-119 BINDING 121-121 BINDING 125-125 BINDING 125-125 BINDING 126-126 BINDING 129-129 BINDING 177-177 BINDING 262-262 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVE
CCCCEEEEEEECCCCCCCEEHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHH
SLVIDVIEPLIKEYAFPAIQANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGC
HHHHHHHHHHHHHHCCCCCEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAYGEEYGIPAPVKKSSPYSIDK
CCCCCCEEEEEEEEEEECCCEEEEECHHHHCCCHHHHHHCCHHCCCCCCCCCCCCCCCCC
NLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGI
HHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCHH
ELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTR
HHHHHHHHHHCCCCCCCCEEHHCHHCCCCCHHHHCCCCEEEEEECCCCCCCEEEEHHHHH
YKRGIEETYSQLVYNGLWFSPLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCEEEEEECCCCC
LYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG
EEEEEEEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
SRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVE
CCCEEEEEEECCCCCCCEEHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHH
SLVIDVIEPLIKEYAFPAIQANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGC
HHHHHHHHHHHHHHCCCCCEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAYGEEYGIPAPVKKSSPYSIDK
CCCCCCEEEEEEEEEEECCCEEEEECHHHHCCCHHHHHHCCHHCCCCCCCCCCCCCCCCC
NLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGI
HHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCHH
ELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTR
HHHHHHHHHHCCCCCCCCEEHHCHHCCCCCHHHHCCCCEEEEEECCCCCCCEEEEHHHHH
YKRGIEETYSQLVYNGLWFSPLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCEEEEEECCCCC
LYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG
EEEEEEEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA