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The map label for this gene is yfdH [C]

Identifier: 113474633

GI number: 113474633

Start: 1279953

End: 1280891

Strand: Reverse

Name: yfdH [C]

Synonym: Tery_0804

Alternate gene names: 113474633

Gene position: 1280891-1279953 (Counterclockwise)

Preceding gene: 113474635

Following gene: 113474630

Centisome position: 16.53

GC content: 34.93

Gene sequence:

>939_bases
ATGAAATATTCTTTAGTAATTCCTATTTATAATGAAGAAAAAAATTTGCCTGAGTTATATCGGCGGCTCAGTGCAGTTAT
GGAGAGAATAGATGGAGATGTAGAATTAATTTTGATTAATGATGGGAGTCGCGATCGCTCTCTCGAAATTATCCGAGAAT
TCCATCGAAAAGATCCTCGAATTTGTTATTTAAGTTTTGCTCGTAACTTCGGACATCAAATTGCTGTTACTGCTGGTTTA
AATTTTGCTAGGGGGGAAGTTATTGTAGTTTTAGATGGAGATTTGCAAGACCCACCGGAATTAATTCCTGACTTAATTGA
AAAGTGGCGACAGGGTTATCAAGTTGTCTATGCTCAACGGACAAAAAGACATCAAGAAAGTTGGTTTAAAAGACTTCCTG
CTTTTATTTATTATCGAGTTTTAAAACGTTTGGCAGATGTGGAAATTCCTATTGATACGGGTGATTTTTGTTTGATGGAT
AGATGTGTAGTAGATCTGTTAAATAAAATGCCAGAAACTAATCGTTATATTCGGGGTTTAAGGGCATGGGTTGGTTTTCG
ACAAACAGCAATTAAGTTTGAGAGGGAACCTCGTTTTGCTGGAAATATTCAATATACTTTTGCGAAATCTTTAACTTTAG
CAATTAATGGTTTGGTGTCTTTTTCTAAGGTACCTTTACGACTGTCTACTTATGTAGGATTATTTGCTGCTTGTGTGGCT
TTATTGATGGCTTGTTTGGTTTTATATTGGCGGATTTTTTATCCAAATTCTCCGTTAACGGGTTTGGCAATTATTATGAT
GGCAATCTTCTTTTTAGGAGCAGTACAATTAGTAAGTATTGGAATTTTAGGAGAATACATCGGAAGAATTTATGAAGAAG
TAAAAGGTAGACCTCTTTATACTTTATCTGAAGTGGTGGGTTTTGAGGATAGAAATTAA

Upstream 100 bases:

>100_bases
CTATAGGTATGGGTCAAAAAGACTTAATTTTTAGAGATTTAGATAATAGTAGAAGATAATTTATTATATCCTAGATAACT
AAAGCCCTATTCCTGATTTT

Downstream 100 bases:

>100_bases
CTTTTTTACCCTGATATCTTAGTTGGGAAAACTATAATTAACTCTCAATTAAATCTGCTGTATAGTAATTGTTTAAATAA
AATGAAAATGTAATTTGGTT

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPRICYLSFARNFGHQIAVTAGL
NFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQRTKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMD
RCVVDLLNKMPETNRYIRGLRAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVA
LLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLYTLSEVVGFEDRN

Sequences:

>Translated_312_residues
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPRICYLSFARNFGHQIAVTAGL
NFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQRTKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMD
RCVVDLLNKMPETNRYIRGLRAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVA
LLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLYTLSEVVGFEDRN
>Mature_312_residues
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPRICYLSFARNFGHQIAVTAGL
NFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQRTKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMD
RCVVDLLNKMPETNRYIRGLRAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVA
LLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLYTLSEVVGFEDRN

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=124, Percent_Identity=30.6451612903226, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788692, Length=305, Percent_Identity=40.327868852459, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1788588, Length=311, Percent_Identity=32.475884244373, Blast_Score=172, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6325441, Length=109, Percent_Identity=33.0275229357798, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585265, Length=122, Percent_Identity=31.1475409836066, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 36037; Mature: 36037

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPR
CCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
ICYLSFARNFGHQIAVTAGLNFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQR
EEEEEHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMDRCVVDLLNKMPETNRYIRGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
RAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVA
HHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLSEVVGFEDRN
HHHHHHCCCCCC
>Mature Secondary Structure
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPR
CCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
ICYLSFARNFGHQIAVTAGLNFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQR
EEEEEHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMDRCVVDLLNKMPETNRYIRGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
RAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVA
HHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLSEVVGFEDRN
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]