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The map label for this gene is cobI [H]

Identifier: 113474607

GI number: 113474607

Start: 1230078

End: 1230776

Strand: Reverse

Name: cobI [H]

Synonym: Tery_0768

Alternate gene names: 113474607

Gene position: 1230776-1230078 (Counterclockwise)

Preceding gene: 113474612

Following gene: 113474606

Centisome position: 15.88

GC content: 41.06

Gene sequence:

>699_bases
ATGACAAAACTAGGAAAACTATATGGATTAGGTATTGGGCCTGGAGACCCAGAGTTACTGACTCTCAAAGCACACCGAAT
TTTAACTACTGTTCCAGTAATTGCTTACCCTACTTCAGAAAACAGCAAATCTTTGGCACGAGCGATCGTAGCTAATGTTA
TTCGTTCTGACCAGACAGAAATTCCGATGTACTTGCCCTTTAATATTCACGAGTCATCCCAACCCTATTATGACCAAGCT
GCCCAACAGATTAGTCAATACCTGGAATTGAAACAAGATGTAGCAGTTTTATGTGAGGGAGAACCGATGCTGTATGGCTC
ATTTATGTATATTTTTCAGCGACTTTCAGGAAAGTTTTCCACTGAAGTTGTGCCCGGAATTTCCTCCATAACGGCAAGCG
CTGCTATGCTCAGTGTGCCAATGACTTACCGCAATGATGTCTTGACCATTATACCTGCTACTTTAGATGAGGTTAAATTA
CGCGATCGCCTAGCTGTTGCCGATGCGGTAGTAATTATCAAATTAGGCAGGCATTTTGCTAAAGTTCGCAATATTCTGGA
TGAGTTAGGGCTGTTGCAGCGGGCACTTTATATTGAAAGGGCAACCCAAACCGAGCAAAAAATTATTAGTATTACTGAGG
TTGAACCAACTGAAGTTCCCTACTGGTCTTTAATTTTAATTCCTAGTCATTTCAATTAA

Upstream 100 bases:

>100_bases
TCCTAACTCTAGTTTGCTTTGAGACTATCCCCAAAAATAAATAAATTGGGACTAGAATAAAACTATGAAAAAACTTTTTT
CAAACTGGTATAATTAAGAA

Downstream 100 bases:

>100_bases
CGGTGAAGAGTTATCAGTTAACAGTACCTCTGAAACCAGAACATTGATCCTAATTCCCTAAGACTTTTATTATGGATAGT
CAAAGAGACAGAATATCAGG

Product: precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTKLGKLYGLGIGPGDPELLTLKAHRILTTVPVIAYPTSENSKSLARAIVANVIRSDQTEIPMYLPFNIHESSQPYYDQA
AQQISQYLELKQDVAVLCEGEPMLYGSFMYIFQRLSGKFSTEVVPGISSITASAAMLSVPMTYRNDVLTIIPATLDEVKL
RDRLAVADAVVIIKLGRHFAKVRNILDELGLLQRALYIERATQTEQKIISITEVEPTEVPYWSLILIPSHFN

Sequences:

>Translated_232_residues
MTKLGKLYGLGIGPGDPELLTLKAHRILTTVPVIAYPTSENSKSLARAIVANVIRSDQTEIPMYLPFNIHESSQPYYDQA
AQQISQYLELKQDVAVLCEGEPMLYGSFMYIFQRLSGKFSTEVVPGISSITASAAMLSVPMTYRNDVLTIIPATLDEVKL
RDRLAVADAVVIIKLGRHFAKVRNILDELGLLQRALYIERATQTEQKIISITEVEPTEVPYWSLILIPSHFN
>Mature_231_residues
TKLGKLYGLGIGPGDPELLTLKAHRILTTVPVIAYPTSENSKSLARAIVANVIRSDQTEIPMYLPFNIHESSQPYYDQAA
QQISQYLELKQDVAVLCEGEPMLYGSFMYIFQRLSGKFSTEVVPGISSITASAAMLSVPMTYRNDVLTIIPATLDEVKLR
DRLAVADAVVIIKLGRHFAKVRNILDELGLLQRALYIERATQTEQKIISITEVEPTEVPYWSLILIPSHFN

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 25881; Mature: 25750

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLGKLYGLGIGPGDPELLTLKAHRILTTVPVIAYPTSENSKSLARAIVANVIRSDQTE
CCCCCCEEECCCCCCCCCEEEEEHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
IPMYLPFNIHESSQPYYDQAAQQISQYLELKQDVAVLCEGEPMLYGSFMYIFQRLSGKFS
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHCCCCC
TEVVPGISSITASAAMLSVPMTYRNDVLTIIPATLDEVKLRDRLAVADAVVIIKLGRHFA
CHHCCCHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVRNILDELGLLQRALYIERATQTEQKIISITEVEPTEVPYWSLILIPSHFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TKLGKLYGLGIGPGDPELLTLKAHRILTTVPVIAYPTSENSKSLARAIVANVIRSDQTE
CCCCCEEECCCCCCCCCEEEEEHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
IPMYLPFNIHESSQPYYDQAAQQISQYLELKQDVAVLCEGEPMLYGSFMYIFQRLSGKFS
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHCCCCC
TEVVPGISSITASAAMLSVPMTYRNDVLTIIPATLDEVKLRDRLAVADAVVIIKLGRHFA
CHHCCCHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVRNILDELGLLQRALYIERATQTEQKIISITEVEPTEVPYWSLILIPSHFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]