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The map label for this gene is ndhD1

Identifier: 113474510

GI number: 113474510

Start: 1074302

End: 1075885

Strand: Reverse

Name: ndhD1

Synonym: Tery_0659

Alternate gene names: 113474510

Gene position: 1075885-1074302 (Counterclockwise)

Preceding gene: 113474511

Following gene: 113474506

Centisome position: 13.88

GC content: 41.86

Gene sequence:

>1584_bases
ATGATGACTAATTTTCCTTGGCTAACTACAATTATCCTATTTCCAATAGTTGCATCTTTGCTACTTCCGATCATTCCTGA
TAAAGACGGCAAAACGGTGCGATGGTACTCCTTAATAGTTGGATTAATTGATTTTGCTATTATTATTGCTGCTTTCTGCA
CAGGATATGATGTTAATAACCCTGAACTTCAACTGGTAGAAAGTTACCCTTGGGTACCTCAGCTAGATTTAAATTGGTCA
GTGGGGGCGGATGGTTTATCTATGCCATTAATTATCCTAACTGGCTTTATCACGACTCTAGCAATTATGGCAGCATGGCC
TGTAAGTTTTAAGCCGAAGCTATTTTACTTTTTGATGTTGGCAATGTACGGCGGTCAAATTGCTGTATTTGCTGTACAAG
ATATGTTGCTATTTTTCCTGGTTTGGGAATTAGAATTAGTGCCTGTTTACCTAATTCTTTCCATCTGGGGTGGTAAACGC
CGGCTATATGCGGCAACTAAGTTTATCCTCTACACAGCGGGTGGCTCATTGTTTATTTTGATTGCGGCTTTAACAATGGC
CTTCTATGGGGATACTGTTAGTTTTGATATGAGGACGATCGCTCTCAAAGATTATGCTTTCAATTTGCAACTGTTGTTAT
ATGCAGCTTTCTTAATTGCTTATGCTGTGAAGTTGCCTATTTTCCCACTACACACCTGGTTACCTGATGCCCACGGGGAG
GCAACGGCACCTGCTCATATGTTGCTGGCTGGAATTTTGCTGAAAATGGGTGGTTATGCTTTACTGCGGATGAATGCGGG
AATGTTACCTGATGCTCATGCGGTCTTTGCTCCGGTGTTGGTAATTTTGGGGGTTGTAAATATTGTTTATGCTGCTTTGA
CGTCTTTTGCTCAACGAAACCTGAAGCGGAAAATTGCCTACTCTTCTATTTCTCACATGGGGTTTGTGTTAATAGGTATG
GCTTCTTTTACTGATATTGGTTTGAGTGGAGCTGTGCTGCAAATGATTTCCCATGGTTTGATAGGGGCGAGTTTGTTCTT
TTTGGTGGGAGCTACTTATGACCGGACTCATACTTTGATTTTGGATGAAATGGGTGGTGTCGGTCAGAAGATGAAAAAGG
TGTTCGCTATGTGGACGACTTGTTCTATGGCTTCTTTGGCTTTGCCCGGAATGAGTGGGTTTGTGGCTGAGGTTATGGTG
TTTATTGGTTTTGCTACCAGTGATGCTTATAGTTCAACTTTTAAGGTTTTAGTGATTTTCTTGTCTGCAGTTGGGGTAAT
TTTGACTCCTATTTATCTGTTGTCAATGTTGCGGGAGATTTTATATGGTCCTGAGAATAAGAAGTTGGTTGAACACGAGG
TTCTCAAGGACGCGGAACCCCGGGAAGTGTTTATTATTGGTTGTTTGTTAGTGCCAATAATTGGTATAGGCTTGTATCCT
AAAATTGTGACTCAGATATATGATGCGACGACTGTACAGTTAACAGCGCGGTTACGAGATTCTGTGCCTGTGTTGATGGG
GCCTGAAAAAGTGGCGTTAACAGATGTGTCTGAGTTGCCGACCCGTGCCCCTGAGATTAAATAA

Upstream 100 bases:

>100_bases
TAATAACTGAATATGCTGTAATAGCATTAGAAATAGGACAACTACCCTCATTATTTATTCTAGGATATTTTTGAATTGAT
TTAATAGTGATTTAACATTT

Downstream 100 bases:

>100_bases
TATGACAGTTAAATTTTGACGGGTTTTCCTCCACGGTAGACCACAGTAGATTTTCTATGAGTAGGGATGTTCTATGTAAC
GTCCCTACAATTTTTTGGTT

Product: NAD(P)H-quinone oxidoreductase subunit 4

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 4 1; NDH-1, chain 4 1

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MMTNFPWLTTIILFPIVASLLLPIIPDKDGKTVRWYSLIVGLIDFAIIIAAFCTGYDVNNPELQLVESYPWVPQLDLNWS
VGADGLSMPLIILTGFITTLAIMAAWPVSFKPKLFYFLMLAMYGGQIAVFAVQDMLLFFLVWELELVPVYLILSIWGGKR
RLYAATKFILYTAGGSLFILIAALTMAFYGDTVSFDMRTIALKDYAFNLQLLLYAAFLIAYAVKLPIFPLHTWLPDAHGE
ATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHAVFAPVLVILGVVNIVYAALTSFAQRNLKRKIAYSSISHMGFVLIGM
ASFTDIGLSGAVLQMISHGLIGASLFFLVGATYDRTHTLILDEMGGVGQKMKKVFAMWTTCSMASLALPGMSGFVAEVMV
FIGFATSDAYSSTFKVLVIFLSAVGVILTPIYLLSMLREILYGPENKKLVEHEVLKDAEPREVFIIGCLLVPIIGIGLYP
KIVTQIYDATTVQLTARLRDSVPVLMGPEKVALTDVSELPTRAPEIK

Sequences:

>Translated_527_residues
MMTNFPWLTTIILFPIVASLLLPIIPDKDGKTVRWYSLIVGLIDFAIIIAAFCTGYDVNNPELQLVESYPWVPQLDLNWS
VGADGLSMPLIILTGFITTLAIMAAWPVSFKPKLFYFLMLAMYGGQIAVFAVQDMLLFFLVWELELVPVYLILSIWGGKR
RLYAATKFILYTAGGSLFILIAALTMAFYGDTVSFDMRTIALKDYAFNLQLLLYAAFLIAYAVKLPIFPLHTWLPDAHGE
ATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHAVFAPVLVILGVVNIVYAALTSFAQRNLKRKIAYSSISHMGFVLIGM
ASFTDIGLSGAVLQMISHGLIGASLFFLVGATYDRTHTLILDEMGGVGQKMKKVFAMWTTCSMASLALPGMSGFVAEVMV
FIGFATSDAYSSTFKVLVIFLSAVGVILTPIYLLSMLREILYGPENKKLVEHEVLKDAEPREVFIIGCLLVPIIGIGLYP
KIVTQIYDATTVQLTARLRDSVPVLMGPEKVALTDVSELPTRAPEIK
>Mature_527_residues
MMTNFPWLTTIILFPIVASLLLPIIPDKDGKTVRWYSLIVGLIDFAIIIAAFCTGYDVNNPELQLVESYPWVPQLDLNWS
VGADGLSMPLIILTGFITTLAIMAAWPVSFKPKLFYFLMLAMYGGQIAVFAVQDMLLFFLVWELELVPVYLILSIWGGKR
RLYAATKFILYTAGGSLFILIAALTMAFYGDTVSFDMRTIALKDYAFNLQLLLYAAFLIAYAVKLPIFPLHTWLPDAHGE
ATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHAVFAPVLVILGVVNIVYAALTSFAQRNLKRKIAYSSISHMGFVLIGM
ASFTDIGLSGAVLQMISHGLIGASLFFLVGATYDRTHTLILDEMGGVGQKMKKVFAMWTTCSMASLALPGMSGFVAEVMV
FIGFATSDAYSSTFKVLVIFLSAVGVILTPIYLLSMLREILYGPENKKLVEHEVLKDAEPREVFIIGCLLVPIIGIGLYP
KIVTQIYDATTVQLTARLRDSVPVLMGPEKVALTDVSELPTRAPEIK

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family

Homologues:

Organism=Homo sapiens, GI251831116, Length=384, Percent_Identity=31.25, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1788613, Length=514, Percent_Identity=35.9922178988327, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI1788827, Length=298, Percent_Identity=25.8389261744966, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788831, Length=298, Percent_Identity=27.1812080536913, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788829, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693160, Length=218, Percent_Identity=31.1926605504587, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367154, Length=267, Percent_Identity=26.9662921348315, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788614, Length=486, Percent_Identity=23.4567901234568, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU4C1_TRIEI (Q118H6)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720571.1
- STRING:   Q118H6
- GeneID:   4243166
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0659
- NMPDR:   fig|203124.1.peg.608
- eggNOG:   COG1008
- HOGENOM:   HBG643593
- OMA:   TSFAQRN
- PhylomeDB:   Q118H6
- ProtClustDB:   PRK02546
- BioCyc:   TERY203124:TERY_0659-MONOMER
- HAMAP:   MF_00491
- InterPro:   IPR022997
- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- PRINTS:   PR01437
- TIGRFAMs:   TIGR01972

Pfam domain/function: PF00361 Oxidored_q1

EC number: 1.6.5.3

Molecular weight: Translated: 57861; Mature: 57861

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14498ce0)-; HASH(0x151749d8)-; HASH(0x153cffe8)-; HASH(0x14519bb4)-; HASH(0x1522de88)-; HASH(0x1418eac4)-; HASH(0x143fb928)-; HASH(0x14ff88fc)-; HASH(0x140647c4)-; HASH(0x950c578)-; HASH(0x15f68800)-; HASH(0x15c257e0)-; HASH(0x15e7147c)-; HASH(0x15bb90b8)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTNFPWLTTIILFPIVASLLLPIIPDKDGKTVRWYSLIVGLIDFAIIIAAFCTGYDVNN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
PELQLVESYPWVPQLDLNWSVGADGLSMPLIILTGFITTLAIMAAWPVSFKPKLFYFLML
CCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AMYGGQIAVFAVQDMLLFFLVWELELVPVYLILSIWGGKRRLYAATKFILYTAGGSLFIL
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCHHHHH
IAALTMAFYGDTVSFDMRTIALKDYAFNLQLLLYAAFLIAYAVKLPIFPLHTWLPDAHGE
HHHHHHHHHCCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCC
ATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHAVFAPVLVILGVVNIVYAALTSFAQRN
CCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRKIAYSSISHMGFVLIGMASFTDIGLSGAVLQMISHGLIGASLFFLVGATYDRTHTLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEE
LDEMGGVGQKMKKVFAMWTTCSMASLALPGMSGFVAEVMVFIGFATSDAYSSTFKVLVIF
EHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSAVGVILTPIYLLSMLREILYGPENKKLVEHEVLKDAEPREVFIIGCLLVPIIGIGLYP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCHH
KIVTQIYDATTVQLTARLRDSVPVLMGPEKVALTDVSELPTRAPEIK
HHHHHHHCCHHHEEHHHHHCCCCEEECCCCEEECCHHHCCCCCCCCH
>Mature Secondary Structure
MMTNFPWLTTIILFPIVASLLLPIIPDKDGKTVRWYSLIVGLIDFAIIIAAFCTGYDVNN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
PELQLVESYPWVPQLDLNWSVGADGLSMPLIILTGFITTLAIMAAWPVSFKPKLFYFLML
CCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AMYGGQIAVFAVQDMLLFFLVWELELVPVYLILSIWGGKRRLYAATKFILYTAGGSLFIL
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCHHHHH
IAALTMAFYGDTVSFDMRTIALKDYAFNLQLLLYAAFLIAYAVKLPIFPLHTWLPDAHGE
HHHHHHHHHCCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCC
ATAPAHMLLAGILLKMGGYALLRMNAGMLPDAHAVFAPVLVILGVVNIVYAALTSFAQRN
CCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRKIAYSSISHMGFVLIGMASFTDIGLSGAVLQMISHGLIGASLFFLVGATYDRTHTLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEE
LDEMGGVGQKMKKVFAMWTTCSMASLALPGMSGFVAEVMVFIGFATSDAYSSTFKVLVIF
EHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSAVGVILTPIYLLSMLREILYGPENKKLVEHEVLKDAEPREVFIIGCLLVPIIGIGLYP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCHH
KIVTQIYDATTVQLTARLRDSVPVLMGPEKVALTDVSELPTRAPEIK
HHHHHHHCCHHHEEHHHHHCCCCEEECCCCEEECCHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA