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The map label for this gene is hemH [H]

Identifier: 113474458

GI number: 113474458

Start: 973082

End: 974287

Strand: Reverse

Name: hemH [H]

Synonym: Tery_0602

Alternate gene names: 113474458

Gene position: 974287-973082 (Counterclockwise)

Preceding gene: 113474463

Following gene: 113474452

Centisome position: 12.57

GC content: 35.57

Gene sequence:

>1206_bases
GTGGTTACAACCCCAGAAAAAATTGAAAATCGAAAAAATTCTATATCTCCAAACCAAAACAGACAAGACAGAGTCGCAGT
ATTATTGATGGGATATGGCGAGGTAGAAAGCTATGAAGATTTTGCCAATTATAATGAACAAGCATTAAATTTACTGACCG
CTAAGTTTGCTCCTGTTCCTACCTGGATATATCCTCCTTTAGCAAAGTTATTGGCTATTTTTGACCTCCATGAATGGAGT
CATCAACATGGTAATTTTATCTCTCCTCATAATGCTATTTTTGAAAGTCAAAGAGCAGGAATTGAAAAAAATCTTCAAGA
TAAATGGGGCGATCGGGTTAAAGTTTTTAAAGCTTTTAATTTCTGCGCTCCCTACTTACCAGAACAAGTATTAAATCAAA
TTAAATCTGAAGGTTTTGATAAGTTATTGATTTATCCTTTGTTAGTAGTTGATTCTATTTTTACTAGTGGTATTGCTGTT
GAACAAGTTAATAAAGCATTGGTAAAATTAGCAGATAAAAATGAACATTGGATTAAAGGTCAACGTTATATTCCTTCTTT
TTATAATGAACCTGATTATATTAATTTAATGGCAAAAATGGTAGAAGAACAGATTGCTAATGATTTAGCGGTTGCTCATT
TACCATCTCAAATTGGTATTGTTTTAACAAATCATGGCTGCCCTCATAAAGCTAAAGGTTTTACTTCTGGAATTGATGAA
AGTCAAACACTTTATGAGTTGGTGCGGGAACGTTTAATTAATCGTTTTGCTTTAATTTCTGTGGGTTGGTTAAACCATGA
TACTCCACTTATTGAATGGACTCAACCAGATGCTAAAACTGCAGCTCAAAATCTGATAGAATTAGGTGCAACAGCTATTA
TATTTATGCCTATTGGTTTTGCTACGGAAAATCACGAAACCTTATTAGATGTTGAGCATATTATTGAAGGTTTGCGTCGA
AAATATCCTGAAGTAACTTATCGGCAAATGCCTTGTGTTAATGACCGCTCAGAATTTTTGCAGATGGCTGGGGAGTGGGC
CAATCTTTATATTGAGGAATTATTGAGTGAAAATGCTTTAGCTGTTAACCCTTCTTTGGCCCTAGCACAGGCAAAGTCGA
CTCATGGTCATAGTCACGATGGAGACCATGGTCATTCTCACGGCGATCATCACCATCATGGTCACCACCACCATCATCAT
CATTAG

Upstream 100 bases:

>100_bases
CACCCATCCCCCCGGTGGGGAATGCTAAACTAACTCAAGAGTCAAATTACTCATGTTCTTTAATTAAGTTAATTAATAAA
TATAACTAAAGGAGCAAAAC

Downstream 100 bases:

>100_bases
ATGTGTCTAGAAAAGGTTCTAATTCTCTTATCTTGCTCTTTTTAAGTTGGCATTTTTGGAAAGCTATAAACTTGGAGAAG
TTTTTACCAACTAGACAAAA

Product: ferrochelatase

Products: NA

Alternate protein names: Heme synthase; Protoheme ferro-lyase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MVTTPEKIENRKNSISPNQNRQDRVAVLLMGYGEVESYEDFANYNEQALNLLTAKFAPVPTWIYPPLAKLLAIFDLHEWS
HQHGNFISPHNAIFESQRAGIEKNLQDKWGDRVKVFKAFNFCAPYLPEQVLNQIKSEGFDKLLIYPLLVVDSIFTSGIAV
EQVNKALVKLADKNEHWIKGQRYIPSFYNEPDYINLMAKMVEEQIANDLAVAHLPSQIGIVLTNHGCPHKAKGFTSGIDE
SQTLYELVRERLINRFALISVGWLNHDTPLIEWTQPDAKTAAQNLIELGATAIIFMPIGFATENHETLLDVEHIIEGLRR
KYPEVTYRQMPCVNDRSEFLQMAGEWANLYIEELLSENALAVNPSLALAQAKSTHGHSHDGDHGHSHGDHHHHGHHHHHH
H

Sequences:

>Translated_401_residues
MVTTPEKIENRKNSISPNQNRQDRVAVLLMGYGEVESYEDFANYNEQALNLLTAKFAPVPTWIYPPLAKLLAIFDLHEWS
HQHGNFISPHNAIFESQRAGIEKNLQDKWGDRVKVFKAFNFCAPYLPEQVLNQIKSEGFDKLLIYPLLVVDSIFTSGIAV
EQVNKALVKLADKNEHWIKGQRYIPSFYNEPDYINLMAKMVEEQIANDLAVAHLPSQIGIVLTNHGCPHKAKGFTSGIDE
SQTLYELVRERLINRFALISVGWLNHDTPLIEWTQPDAKTAAQNLIELGATAIIFMPIGFATENHETLLDVEHIIEGLRR
KYPEVTYRQMPCVNDRSEFLQMAGEWANLYIEELLSENALAVNPSLALAQAKSTHGHSHDGDHGHSHGDHHHHGHHHHHH
H
>Mature_401_residues
MVTTPEKIENRKNSISPNQNRQDRVAVLLMGYGEVESYEDFANYNEQALNLLTAKFAPVPTWIYPPLAKLLAIFDLHEWS
HQHGNFISPHNAIFESQRAGIEKNLQDKWGDRVKVFKAFNFCAPYLPEQVLNQIKSEGFDKLLIYPLLVVDSIFTSGIAV
EQVNKALVKLADKNEHWIKGQRYIPSFYNEPDYINLMAKMVEEQIANDLAVAHLPSQIGIVLTNHGCPHKAKGFTSGIDE
SQTLYELVRERLINRFALISVGWLNHDTPLIEWTQPDAKTAAQNLIELGATAIIFMPIGFATENHETLLDVEHIIEGLRR
KYPEVTYRQMPCVNDRSEFLQMAGEWANLYIEELLSENALAVNPSLALAQAKSTHGHSHDGDHGHSHGDHHHHGHHHHHH
H

Specific function: Catalyzes the ferrous insertion into protoporphyrin IX [H]

COG id: COG0276

COG function: function code H; Protoheme ferro-lyase (ferrochelatase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferrochelatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001015
- InterPro:   IPR019772 [H]

Pfam domain/function: PF00762 Ferrochelatase [H]

EC number: =4.99.1.1 [H]

Molecular weight: Translated: 45585; Mature: 45585

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTPEKIENRKNSISPNQNRQDRVAVLLMGYGEVESYEDFANYNEQALNLLTAKFAPVP
CCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCC
TWIYPPLAKLLAIFDLHEWSHQHGNFISPHNAIFESQRAGIEKNLQDKWGDRVKVFKAFN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
FCAPYLPEQVLNQIKSEGFDKLLIYPLLVVDSIFTSGIAVEQVNKALVKLADKNEHWIKG
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
QRYIPSFYNEPDYINLMAKMVEEQIANDLAVAHLPSQIGIVLTNHGCPHKAKGFTSGIDE
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCC
SQTLYELVRERLINRFALISVGWLNHDTPLIEWTQPDAKTAAQNLIELGATAIIFMPIGF
HHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCC
ATENHETLLDVEHIIEGLRRKYPEVTYRQMPCVNDRSEFLQMAGEWANLYIEELLSENAL
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
AVNPSLALAQAKSTHGHSHDGDHGHSHGDHHHHGHHHHHHH
EECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVTTPEKIENRKNSISPNQNRQDRVAVLLMGYGEVESYEDFANYNEQALNLLTAKFAPVP
CCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCC
TWIYPPLAKLLAIFDLHEWSHQHGNFISPHNAIFESQRAGIEKNLQDKWGDRVKVFKAFN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
FCAPYLPEQVLNQIKSEGFDKLLIYPLLVVDSIFTSGIAVEQVNKALVKLADKNEHWIKG
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
QRYIPSFYNEPDYINLMAKMVEEQIANDLAVAHLPSQIGIVLTNHGCPHKAKGFTSGIDE
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCC
SQTLYELVRERLINRFALISVGWLNHDTPLIEWTQPDAKTAAQNLIELGATAIIFMPIGF
HHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCC
ATENHETLLDVEHIIEGLRRKYPEVTYRQMPCVNDRSEFLQMAGEWANLYIEELLSENAL
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
AVNPSLALAQAKSTHGHSHDGDHGHSHGDHHHHGHHHHHHH
EECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA