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The map label for this gene is trpB

Identifier: 113474438

GI number: 113474438

Start: 932940

End: 934169

Strand: Direct

Name: trpB

Synonym: Tery_0581

Alternate gene names: 113474438

Gene position: 932940-934169 (Clockwise)

Preceding gene: 113474436

Following gene: 113474439

Centisome position: 12.04

GC content: 46.75

Gene sequence:

>1230_bases
GTGACTATTACACCTCTAAATCCAACTTCCACTCAACAACCAGATTCTCTAGGCAGATTTGGCAAGTTTGGCGGTAAATA
TGTCCCAGAAACATTAATGCCTGCCCTATTGCAGCTAGAGACAGCCTGTAAAAAATACAGTCAAGACCCTACTTTTAAAC
AAGAACTTCAACAACTATTACGAGACTATGTAGGTCGCCCTAGCCCTCTTTACTTCGCCGAACGTTTGACAGCTCATTAC
ACCAAACCTGATGGTACAGGGCCACAAATTTACCTGAAAAGGGAAGACCTTAACCATACAGGAGCCCACAAAATCAACAA
TGCTCTAGGCCAAGCCTTATTAGCCCAGAGAATGGGCAAACAACGCATTATTGCTGAAACAGGTGCAGGTCAACATGGTG
TGGCCACCGCTACAGTTTGCGCTCGGTTTGGCTTGAAGTGTGTCATTTACATGGGCATTCACGACATGGAACGTCAAGCT
CTAAATGTATTCAGAATGCGACTGATGGGGGCGGAGGTGCGACCAGTAGAAGCTGGCACCGGTACCCTCAAAGATGCAAC
TTCGGAAGCTATTCGCGACTGGGTGACTAATGTGGAGACAACCCATTATATTCTAGGCTCCGTTGCTGGGCCCCATCCTT
ACCCAATGATGGTGCGTGATTTTCATGCTGTCATTGGGGTCGAAACCCGCGCTCAATGTTTGGAAAAATGGAATGGTTTG
CCTGACATTTTGATGGCTTGTGTTGGCGGGGGGTCTAATGCCATGGGATTATTCCATGAGTTTATTAATGATCCGTCGGT
GCGGATGATCGGTGTGGAAGCTGCTGGTAAGGGAGTTGATACGAATAAGCATGCTGCGACTCTGACTCTTGGTCGAGTAG
GTGTGTTGCATGGGGCAATGAGTTATTTGTTGCAGGATGAGGAAGGTCAGATAATAGAACCCCACTCTATTAGCGCTGGT
TTAGATTATCCTGGAGTAGGACCTGAGCATAGCTTTTTAAAGGATAGTGGTAGAGTCGAATATTATAGTGTGACCGATAA
TGAGGCGGTGGCAGCTTTTCAACGTTTGTCTCAGTTAGAGGGTATTATTCCAGCTTTAGAGACTGCTCATGCGATCGCTT
ATCTAGAAACTCTTTGCCCACAGTTAAGTGGTAGTCCCCGCATTGTCTTTAATTGCTCCGGCCGTGGGGATAAAGACGTG
CAGACAGTAGGGAAGTTTTTGGAGGGGTAA

Upstream 100 bases:

>100_bases
TAATCTCTTAAACAAGAATCTCCCATGATAATTAATCTTATTTAATGTTTAATGGTGAGAGTATTAAAATTCAAAATTTT
CTATTATTGAGAAATAATTC

Downstream 100 bases:

>100_bases
TTAATTCTTAGAGGTTTGGACACCAAACCTCTACCCATAACAGAAATTTCAGATTAAAGGCACTTATGCATTTACAGCAG
ATTTCAGGCCAATGATGTAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLLRDYVGRPSPLYFAERLTAHY
TKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGKQRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQA
LNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGL
PDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAMSYLLQDEEGQIIEPHSISAG
LDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLEGIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDV
QTVGKFLEG

Sequences:

>Translated_409_residues
MTITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLLRDYVGRPSPLYFAERLTAHY
TKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGKQRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQA
LNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGL
PDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAMSYLLQDEEGQIIEPHSISAG
LDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLEGIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDV
QTVGKFLEG
>Mature_408_residues
TITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLLRDYVGRPSPLYFAERLTAHYT
KPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGKQRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQAL
NVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGLP
DILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAMSYLLQDEEGQIIEPHSISAGL
DYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLEGIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDVQ
TVGKFLEG

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=55.8974358974359, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=390, Percent_Identity=57.6923076923077, Blast_Score=460, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_TRIEI (Q118P8)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720499.1
- ProteinModelPortal:   Q118P8
- SMR:   Q118P8
- STRING:   Q118P8
- GeneID:   4244607
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0581
- NMPDR:   fig|203124.1.peg.3583
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- PhylomeDB:   Q118P8
- ProtClustDB:   PRK04346
- BioCyc:   TERY203124:TERY_0581-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 44526; Mature: 44395

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLL
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYVGRPSPLYFAERLTAHYTKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGK
HHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
QRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQALNVFRMRLMGAEVRPVEAGT
HHEEEECCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCC
GTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGL
CCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
PDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAM
HHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHH
SYLLQDEEGQIIEPHSISAGLDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLE
HHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
GIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDVQTVGKFLEG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLL
CCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYVGRPSPLYFAERLTAHYTKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGK
HHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
QRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQALNVFRMRLMGAEVRPVEAGT
HHEEEECCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCC
GTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGL
CCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
PDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAM
HHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHH
SYLLQDEEGQIIEPHSISAGLDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLE
HHHHCCCCCCEECCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
GIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDVQTVGKFLEG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA