Click here to switch to the map view.

The map label for this gene is dapL2 [H]

Identifier: 113474355

GI number: 113474355

Start: 779543

End: 780718

Strand: Direct

Name: dapL2 [H]

Synonym: Tery_0487

Alternate gene names: 113474355

Gene position: 779543-780718 (Clockwise)

Preceding gene: 113474354

Following gene: 113474356

Centisome position: 10.06

GC content: 34.01

Gene sequence:

>1176_bases
ATGGAGTTTGCCAAAAAACTAGAAAAAATATCGCCTTATCCCTTAACCGAAATTAACCGTAAAAAAAATGAATTAATCGA
CAGAGGAGTTGACATTATCAATTTTGGTGCAGGAGATCCAGACCAACCGACACCAAATCATATTGTTCAAGCAATGCATG
AAGCAATTAAAGATTCAACAAATCACCATTATCCTCCTATAAAAGGTCTAAAAGAATATAGACAAGCCGCAGCAGATTGG
ATGAAGCGTAGGTTTGGCATTGAAGATTTGAACTCAGAAACAGAGGTAATTTCCTCTATAGGTTCTAAAGAGTCAATTCA
CAATCTTTTTCTGGCTTTTGTAAATCCAGGGGATTATGCTATAATACCAGACCCTGGTTATCCAGTTTATCGGACATCAA
CAATTTTTACATTAGGTCAACCTTACTCGATGCAACTTAGGGCTGAAAATGGATTTTTACCAATTTTAAGTAATATTCCT
CAAGAAGTAGCTGAAAAAGCTAAATTATTGTGGATTAATTATCCTAATAATCCTACAGGTGCTACAGCTAGCTTAGAGTT
TTTTGAAGAATTAGTAGGTTTTTGTAAACATTATGACATATTGTTATGCCACGACAATGCTTATTCTGAAATAGCTTATG
ATAATTATAAACCTCCTAGTATATTACAAGTTCCTAACGCTAAAGATATAGCAATTGAATTTCATAGCTTATCCAAAACC
TATAATATGTCAGGATGGCGCATTGGTTTTGTAGCAGGAAATAGTCTAGGAATAAAAGGATTAAGTCAAGTAAAATCCAA
CATAGATTCTGGAGTATTTCAAGCCATTCAAAAAGCTGCAACCGAAGCTTTTGTTTCTACAACCGAAAAACACTTACAAA
GTCTAGTGGCAGTTTATCAAAAACGACGAGATATTCTCATCAAAGGTTTGCAATCTTTAGGTTATCCCATTAAAGCAAAC
TTAGCCAGTTTATATGCATGGGTTCCAGTTCCTAAAAATTATACATCTCAAGAATTTGCTACTCTTTTACTAGAAAAATG
TGGCATTATCGTAGTGCCTGGAAACGCTTATGGTACATCAGGAGAAGGATTTATTCGTATTGCGTTAACAGTAGAAGACA
AAAGAATTTCTCAAGCATTACAAAGAATTAAAGATTCAGGTCTTAATTACATATAA

Upstream 100 bases:

>100_bases
AATATTTTAATTTTTATTTAAGAAAACTACCTCAGCAACTTTCAAAATAAACTGTACTATGTCCACATTAATTAATTGCA
GGAGCTAATAAAAAATAATC

Downstream 100 bases:

>100_bases
ATATTTAGACAAAAAAACTATCCTTTTAAATTGAATTACTATATTTAAGTTTTATTTAATTATTCTCTATTTTTTTTCAA
CTATTTTATTATCTATACTA

Product: LL-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT 2; DAP-aminotransferase 2; LL-DAP-aminotransferase 2 [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MEFAKKLEKISPYPLTEINRKKNELIDRGVDIINFGAGDPDQPTPNHIVQAMHEAIKDSTNHHYPPIKGLKEYRQAAADW
MKRRFGIEDLNSETEVISSIGSKESIHNLFLAFVNPGDYAIIPDPGYPVYRTSTIFTLGQPYSMQLRAENGFLPILSNIP
QEVAEKAKLLWINYPNNPTGATASLEFFEELVGFCKHYDILLCHDNAYSEIAYDNYKPPSILQVPNAKDIAIEFHSLSKT
YNMSGWRIGFVAGNSLGIKGLSQVKSNIDSGVFQAIQKAATEAFVSTTEKHLQSLVAVYQKRRDILIKGLQSLGYPIKAN
LASLYAWVPVPKNYTSQEFATLLLEKCGIIVVPGNAYGTSGEGFIRIALTVEDKRISQALQRIKDSGLNYI

Sequences:

>Translated_391_residues
MEFAKKLEKISPYPLTEINRKKNELIDRGVDIINFGAGDPDQPTPNHIVQAMHEAIKDSTNHHYPPIKGLKEYRQAAADW
MKRRFGIEDLNSETEVISSIGSKESIHNLFLAFVNPGDYAIIPDPGYPVYRTSTIFTLGQPYSMQLRAENGFLPILSNIP
QEVAEKAKLLWINYPNNPTGATASLEFFEELVGFCKHYDILLCHDNAYSEIAYDNYKPPSILQVPNAKDIAIEFHSLSKT
YNMSGWRIGFVAGNSLGIKGLSQVKSNIDSGVFQAIQKAATEAFVSTTEKHLQSLVAVYQKRRDILIKGLQSLGYPIKAN
LASLYAWVPVPKNYTSQEFATLLLEKCGIIVVPGNAYGTSGEGFIRIALTVEDKRISQALQRIKDSGLNYI
>Mature_391_residues
MEFAKKLEKISPYPLTEINRKKNELIDRGVDIINFGAGDPDQPTPNHIVQAMHEAIKDSTNHHYPPIKGLKEYRQAAADW
MKRRFGIEDLNSETEVISSIGSKESIHNLFLAFVNPGDYAIIPDPGYPVYRTSTIFTLGQPYSMQLRAENGFLPILSNIP
QEVAEKAKLLWINYPNNPTGATASLEFFEELVGFCKHYDILLCHDNAYSEIAYDNYKPPSILQVPNAKDIAIEFHSLSKT
YNMSGWRIGFVAGNSLGIKGLSQVKSNIDSGVFQAIQKAATEAFVSTTEKHLQSLVAVYQKRRDILIKGLQSLGYPIKAN
LASLYAWVPVPKNYTSQEFATLLLEKCGIIVVPGNAYGTSGEGFIRIALTVEDKRISQALQRIKDSGLNYI

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=328, Percent_Identity=27.4390243902439, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI169881279, Length=328, Percent_Identity=27.4390243902439, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI56713256, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI56713254, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI169881281, Length=327, Percent_Identity=25.3822629969419, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=21.4659685863874, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7705897, Length=291, Percent_Identity=23.7113402061856, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI33469970, Length=291, Percent_Identity=23.7113402061856, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=37.17277486911, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1786816, Length=356, Percent_Identity=22.1910112359551, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788627, Length=256, Percent_Identity=26.953125, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=24.1935483870968, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=22.3076923076923, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=390, Percent_Identity=22.3076923076923, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=293, Percent_Identity=21.8430034129693, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71981209, Length=408, Percent_Identity=24.0196078431373, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=18.974358974359, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573069, Length=382, Percent_Identity=21.4659685863874, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24646114, Length=382, Percent_Identity=21.4659685863874, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28573067, Length=382, Percent_Identity=21.4659685863874, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28573065, Length=382, Percent_Identity=21.4659685863874, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=21.4285714285714, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43634; Mature: 43634

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFAKKLEKISPYPLTEINRKKNELIDRGVDIINFGAGDPDQPTPNHIVQAMHEAIKDST
CCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCC
NHHYPPIKGLKEYRQAAADWMKRRFGIEDLNSETEVISSIGSKESIHNLFLAFVNPGDYA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCHHHHHHEEEEEECCCCEE
IIPDPGYPVYRTSTIFTLGQPYSMQLRAENGFLPILSNIPQEVAEKAKLLWINYPNNPTG
EECCCCCCEEEEEEEEEECCCCEEEEECCCCCCHHHHHCHHHHHCCCEEEEEECCCCCCC
ATASLEFFEELVGFCKHYDILLCHDNAYSEIAYDNYKPPSILQVPNAKDIAIEFHSLSKT
CHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCCCCCEEECCCCCEEEEEEEHHCCE
YNMSGWRIGFVAGNSLGIKGLSQVKSNIDSGVFQAIQKAATEAFVSTTEKHLQSLVAVYQ
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRDILIKGLQSLGYPIKANLASLYAWVPVPKNYTSQEFATLLLEKCGIIVVPGNAYGTS
HHHHHHHHHHHHCCCCHHCCHHHHEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCC
GEGFIRIALTVEDKRISQALQRIKDSGLNYI
CCCEEEEEEEECHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEFAKKLEKISPYPLTEINRKKNELIDRGVDIINFGAGDPDQPTPNHIVQAMHEAIKDST
CCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCC
NHHYPPIKGLKEYRQAAADWMKRRFGIEDLNSETEVISSIGSKESIHNLFLAFVNPGDYA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCHHHHHHEEEEEECCCCEE
IIPDPGYPVYRTSTIFTLGQPYSMQLRAENGFLPILSNIPQEVAEKAKLLWINYPNNPTG
EECCCCCCEEEEEEEEEECCCCEEEEECCCCCCHHHHHCHHHHHCCCEEEEEECCCCCCC
ATASLEFFEELVGFCKHYDILLCHDNAYSEIAYDNYKPPSILQVPNAKDIAIEFHSLSKT
CHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCCCCCEEECCCCCEEEEEEEHHCCE
YNMSGWRIGFVAGNSLGIKGLSQVKSNIDSGVFQAIQKAATEAFVSTTEKHLQSLVAVYQ
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRDILIKGLQSLGYPIKANLASLYAWVPVPKNYTSQEFATLLLEKCGIIVVPGNAYGTS
HHHHHHHHHHHHCCCCHHCCHHHHEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCC
GEGFIRIALTVEDKRISQALQRIKDSGLNYI
CCCEEEEEEEECHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA