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The map label for this gene is map [C]

Identifier: 113474280

GI number: 113474280

Start: 628071

End: 628838

Strand: Direct

Name: map [C]

Synonym: Tery_0402

Alternate gene names: 113474280

Gene position: 628071-628838 (Clockwise)

Preceding gene: 113474279

Following gene: 113474281

Centisome position: 8.1

GC content: 38.8

Gene sequence:

>768_bases
ATGGAAACTGAAACTATCGTTTTATTATCGAAAAGAGAAATAGAAAAAATGCGTCAAGCAGGACGTTTGGCAGCAAGGTT
GTTAAATCATCTTGAGCCTCTTGTCAAACCAGGAGTAACTACTTTGGAATTAGATGAGGAAGCCGAACGTTGGACACAAG
CTCATGGCGCCCGTAGTGCACCCCTTGGTTATCGTGGTTTTCCTAAGTCTATTTGTACTAGCATTAATGAAGTAATTTGT
CACGGTATTCCTAGTGAAAAACAGGTCTTAAAAGAGGGCGATATTATTAATATTGATGTGACACCCATTCTTGATGGTTA
TCATGGAGATACTTCTAAAACTTTTTTCGTTGGTACACCTTCTCCACTGGCAAAAAAACTAGTTGAAGTGACGGAAAAAT
GTATGTATTTAGGTATTGCTGAAGTTAAGCCTGGAAATAAAATTGGGGATATTGGAGCTGCTATTCAAGAGTATGCTGAA
GCACAAGGTTTTTCTGTGGTTAGAGATTTTGTAGGTCATGGTGTGAGTAAAATTTTTCATACTGCACCACAAATTCCTCA
TTATGGCACTAGGGGAAAAGGAAAAAAGTTACGAGCTGGAATGGTATTTACTATTGAACCGATGATTAATGAAGGTACTT
GGGAAGGTCTAGTACTTGAGGACGGTTGGACTGCTATTACTATAGATCGTAAGCTATCAGCACAATTTGAACATACTGTG
GCGGTAACAGAAACAGGGGTAGAAATATTGACTCAGTATGAGGGGTAA

Upstream 100 bases:

>100_bases
ATACCGCAGATTTCATATCAGTGAGGTACAGCTATCGTAGGCAAGATGCCTATGCTACAAAGGTTTTATTATTAATACTC
GAATCTTAATTAAAGAAGCA

Downstream 100 bases:

>100_bases
TTACTGAGGTCAAAAGTTGGATCAAAATTTACATCATTGTGTATAGATGTCTAATTTCTTAGAAGGAAATCAATATTGCA
CAAAAAAATGCCATTAAACC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSAPLGYRGFPKSICTSINEVIC
HGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTPSPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAE
AQGFSVVRDFVGHGVSKIFHTAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTV
AVTETGVEILTQYEG

Sequences:

>Translated_255_residues
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSAPLGYRGFPKSICTSINEVIC
HGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTPSPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAE
AQGFSVVRDFVGHGVSKIFHTAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTV
AVTETGVEILTQYEG
>Mature_255_residues
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSAPLGYRGFPKSICTSINEVIC
HGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTPSPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAE
AQGFSVVRDFVGHGVSKIFHTAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTV
AVTETGVEILTQYEG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=51.2, Blast_Score=260, Evalue=8e-70,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=44.9799196787149, Blast_Score=214, Evalue=9e-56,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=53.8461538461538, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=47.0119521912351, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323273, Length=249, Percent_Identity=48.5943775100402, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=48.1781376518219, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24583427, Length=243, Percent_Identity=47.7366255144033, Blast_Score=221, Evalue=3e-58,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27997; Mature: 27997

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCC
PLGYRGFPKSICTSINEVICHGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTP
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEECC
SPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAEAQGFSVVRDFVGHGVSKIFH
CHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTV
CCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEECCCEEEEECCHHCCCHHHEE
AVTETGVEILTQYEG
EEEHHHHHHHHCCCC
>Mature Secondary Structure
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCC
PLGYRGFPKSICTSINEVICHGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTP
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEECC
SPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAEAQGFSVVRDFVGHGVSKIFH
CHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTV
CCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEECCCEEEEECCHHCCCHHHEE
AVTETGVEILTQYEG
EEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]