BacMap

Definition	Trichodesmium erythraeum IMS101 chromosome, complete genome.
Accession	NC_008312
Length	7,750,108

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The map label for this gene is rot [H]

Identifier: 113474192

GI number: 113474192

Start: 460361

End: 460780

Strand: Direct

Name: rot [H]

Synonym: Tery_0301

Alternate gene names: 113474192

Gene position: 460361-460780 (Clockwise)

Preceding gene: 113474191

Following gene: 113474193

Centisome position: 5.94

GC content: 34.76

Gene sequence:

>420_bases
ATGACACGAGCTATCATGGAAACAGAGAAGGGGACAATTAATCTAGAATTGTTTGATAATGATGCTCCTAATACTGTAAA
AAATTTTGTTGAATTAAGTGAAAAAGGATTTTATGATGGCTTAAATTTTCATCGTGTTATTCCTAATTTTATGATTCAAG
GAGGTTGCCCAAAAGGTACGGGTACAGGTGGTCCTGGTTATAAAATCAAGTGTGAAATTAATAGTAATAAGCATTTAGCT
GGCACTTTATCCATGGCTCATGCTGGTAAAGATACAGGTGGCAGTCAATTCTTTATTTGTCATGCTCCTCAACCTCATTT
AGATGGCGTTCATACAACTTTTGGAAAAACTGAAGATATGGAGGTTGTCAATGCTATTGGTCAGGGTGATAAAATTATTT
CTGTAAAGATTGAGAAGTAA

Upstream 100 bases:

>100_bases
GTCAATCTGAAGCTACTTTTTTAAATGTCGCTAGACTGGAAAAAGATTTTTGGCAAATGGCGTATAATGCGACTAATTAA
ATTTAGGAGAAATTAAAAAA

Downstream 100 bases:

>100_bases
TTTAAATCTACTCCATCTATATCTATAATTTTTGATGTAGATGGGGATTGTTTATAGAATTAGTTTGATGTCTATAGCAT
ACAATTTTTGAATTTTAGGG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MTRAIMETEKGTINLELFDNDAPNTVKNFVELSEKGFYDGLNFHRVIPNFMIQGGCPKGTGTGGPGYKIKCEINSNKHLA
GTLSMAHAGKDTGGSQFFICHAPQPHLDGVHTTFGKTEDMEVVNAIGQGDKIISVKIEK

Sequences:

>Translated_139_residues
MTRAIMETEKGTINLELFDNDAPNTVKNFVELSEKGFYDGLNFHRVIPNFMIQGGCPKGTGTGGPGYKIKCEINSNKHLA
GTLSMAHAGKDTGGSQFFICHAPQPHLDGVHTTFGKTEDMEVVNAIGQGDKIISVKIEK
>Mature_138_residues
TRAIMETEKGTINLELFDNDAPNTVKNFVELSEKGFYDGLNFHRVIPNFMIQGGCPKGTGTGGPGYKIKCEINSNKHLAG
TLSMAHAGKDTGGSQFFICHAPQPHLDGVHTTFGKTEDMEVVNAIGQGDKIISVKIEK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=128, Percent_Identity=48.4375, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI24308049, Length=130, Percent_Identity=48.4615384615385, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI64276486, Length=129, Percent_Identity=37.984496124031, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI4758950, Length=131, Percent_Identity=48.0916030534351, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI10863927, Length=125, Percent_Identity=49.6, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI19557636, Length=119, Percent_Identity=44.5378151260504, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI256017253, Length=124, Percent_Identity=49.1935483870968, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI221139811, Length=124, Percent_Identity=49.1935483870968, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI256017251, Length=124, Percent_Identity=49.1935483870968, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI6631100, Length=121, Percent_Identity=48.7603305785124, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI178057341, Length=125, Percent_Identity=48, Blast_Score=86, Evalue=8e-18,
Organism=Homo sapiens, GI4505991, Length=131, Percent_Identity=47.3282442748092, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI209417936, Length=125, Percent_Identity=47.2, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI30102944, Length=125, Percent_Identity=47.2, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI219842199, Length=125, Percent_Identity=47.2, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI4826932, Length=144, Percent_Identity=42.3611111111111, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI310127646, Length=133, Percent_Identity=42.8571428571429, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI310114371, Length=133, Percent_Identity=42.8571428571429, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI310119221, Length=133, Percent_Identity=42.8571428571429, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI310129267, Length=132, Percent_Identity=45.4545454545455, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI310120620, Length=132, Percent_Identity=45.4545454545455, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI5031987, Length=125, Percent_Identity=47.2, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI310110104, Length=132, Percent_Identity=43.9393939393939, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI150418007, Length=125, Percent_Identity=44.8, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI42560244, Length=140, Percent_Identity=42.1428571428571, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI169164185, Length=125, Percent_Identity=44.8, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI169163623, Length=125, Percent_Identity=44.8, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI169163387, Length=125, Percent_Identity=44.8, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI22547212, Length=116, Percent_Identity=42.2413793103448, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI7657473, Length=116, Percent_Identity=42.2413793103448, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI22547215, Length=116, Percent_Identity=44.8275862068966, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI310114540, Length=125, Percent_Identity=44.8, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI310127745, Length=125, Percent_Identity=44.8, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI310119290, Length=125, Percent_Identity=44.8, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI5174637, Length=131, Percent_Identity=43.5114503816794, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI45439316, Length=125, Percent_Identity=43.2, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI303305009, Length=125, Percent_Identity=43.2, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI310132444, Length=125, Percent_Identity=43.2, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI310113152, Length=125, Percent_Identity=43.2, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI20911035, Length=138, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI169214050, Length=125, Percent_Identity=43.2, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI239751853, Length=125, Percent_Identity=43.2, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI113428306, Length=125, Percent_Identity=43.2, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI5454154, Length=124, Percent_Identity=40.3225806451613, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789763, Length=134, Percent_Identity=41.044776119403, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1786736, Length=95, Percent_Identity=43.1578947368421, Blast_Score=64, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539496, Length=132, Percent_Identity=50.7575757575758, Blast_Score=118, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17506307, Length=131, Percent_Identity=49.618320610687, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17552780, Length=137, Percent_Identity=48.9051094890511, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17506311, Length=132, Percent_Identity=46.2121212121212, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71997782, Length=121, Percent_Identity=42.1487603305785, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565860, Length=139, Percent_Identity=45.3237410071942, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17532641, Length=111, Percent_Identity=45.945945945946, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17559074, Length=132, Percent_Identity=44.6969696969697, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71980590, Length=138, Percent_Identity=37.6811594202899, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71980594, Length=138, Percent_Identity=37.6811594202899, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539498, Length=127, Percent_Identity=45.6692913385827, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17566266, Length=132, Percent_Identity=42.4242424242424, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17552782, Length=132, Percent_Identity=43.1818181818182, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551282, Length=133, Percent_Identity=43.609022556391, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17551284, Length=133, Percent_Identity=43.609022556391, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17532643, Length=123, Percent_Identity=43.0894308943089, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17552784, Length=129, Percent_Identity=35.6589147286822, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323562, Length=132, Percent_Identity=50, Blast_Score=98, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320359, Length=118, Percent_Identity=49.1525423728814, Blast_Score=85, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321848, Length=132, Percent_Identity=47.7272727272727, Blast_Score=84, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320510, Length=127, Percent_Identity=45.6692913385827, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323246, Length=143, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17986117, Length=151, Percent_Identity=47.0198675496689, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357249, Length=136, Percent_Identity=37.5, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19922376, Length=116, Percent_Identity=45.6896551724138, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI20130249, Length=125, Percent_Identity=49.6, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24650807, Length=122, Percent_Identity=45.0819672131148, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24664125, Length=125, Percent_Identity=48, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357783, Length=125, Percent_Identity=48, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549139, Length=125, Percent_Identity=48, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19922912, Length=125, Percent_Identity=48.8, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17647301, Length=115, Percent_Identity=45.2173913043478, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24652460, Length=119, Percent_Identity=37.8151260504202, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24586038, Length=129, Percent_Identity=41.0852713178295, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17136360, Length=128, Percent_Identity=39.0625, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15053; Mature: 14922

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAIMETEKGTINLELFDNDAPNTVKNFVELSEKGFYDGLNFHRVIPNFMIQGGCPKGT
CCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCEEECCCCCCC
GTGGPGYKIKCEINSNKHLAGTLSMAHAGKDTGGSQFFICHAPQPHLDGVHTTFGKTEDM
CCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
EVVNAIGQGDKIISVKIEK
HHHHHCCCCCEEEEEEECC
>Mature Secondary Structure 
TRAIMETEKGTINLELFDNDAPNTVKNFVELSEKGFYDGLNFHRVIPNFMIQGGCPKGT
CCCCEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCEEECCCCCCC
GTGGPGYKIKCEINSNKHLAGTLSMAHAGKDTGGSQFFICHAPQPHLDGVHTTFGKTEDM
CCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
EVVNAIGQGDKIISVKIEK
HHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA