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The map label for this gene is groEL

Identifier: 113474165

GI number: 113474165

Start: 415937

End: 417622

Strand: Direct

Name: groEL

Synonym: Tery_0270

Alternate gene names: 113474165

Gene position: 415937-417622 (Clockwise)

Preceding gene: 113474164

Following gene: 113474166

Centisome position: 5.37

GC content: 43.71

Gene sequence:

>1686_bases
ATGGCTAAAATTGTAGAATTTGATGATAAGTCCAGACGCTCTCTAGAACGAGGTATCAATACTCTAGCTGATGCGGTCAG
AATTACTATGGGCCCAAAGGGTAGAAATGTATTACTAGAGAAAAAATATGGCGCTCCCCAAATTGTTAATGATGGTATTA
CAGTAGCTAAGGATATTGAACTGGAAGACCCTCTAGAAAACACTGGGGCTAAATTAATTCAAGAAGTGGCGTCTAAAACT
AAGGATATTGCTGGAGATGGCACAACTACAGCTACTGTTTTAGCTCAGTCTATGATTAAAGAAGGCCTCAAAAACGTAGC
TGCTGGTGCGAACCCAGTGGCAGTTCGTAGAGGGATTGAGAAAACTGTTAGTCTGCTAGTGAAAGAAATACAAACAGTTG
CTAAACCGGTAGAGGGAGAAGCGATCGCTCAAGTTGCTACGGTATCTGCAGGTGGTGATGCAGAGGTAGGCAGAATGATT
TCTGAGGCCATGGATAAAGTTACCAAGGATGGGGTAATTACTGTTGAAGAGTCTAAGTCTCTTTCTACAGACTTAGAGGT
TGTGGAAGGAATGCAAATTGATCGCGGTTATCTTTCTCCTTATTTTGTGACTGATCAAGAACGGTTAGTAGTCGACTTTG
AAAATGCTCGCATCTTAATTACTGATAAGAAAATCTCTTCTATTCAAGATTTGGTACCGGTACTGGAAAAAGTTGCTCGT
GCTGGTCAGTCTTTATTAATTATTGCTGAGGATATTGAAGGGGAAGCTTTAGCTACTTTGGTGGTTAATAAAGCAAGGGG
TGTACTGAATGTTGCTGCAGTGAAGGCTCCTGGTTTTGGCGATCGCCGTAAGGCAATGCTCCAAGATATTGCTATTCTCA
CGGGTGGTCAACTCATCTCGGAAGAGGTTGGTCTGAGTCTAGAGATGGTAGACCTAGATATGATGGGTATTGGTCGCAAA
ATTTCTATTAACAAGGATAACACAACTATTGTTGCTGATGGGGGAACGGCTGAGGAAGTTAAAAAGCGGATCGCTCAAAT
TCGCAAACAGCTTGGTGAAAGCGACTCTGATTATGATAAAGAAAAGTTACAAGAGCGCATTGCTAAGTTAGCTGGTGGGG
TGGCAGTCATTAAGGTTGGTGCTGCTACTGAAACTGAGCTTAAAGACCGGAAGTTACGCATTGAGGATGCTTTGAATGCG
ACAAAGGCTGCTGTAGAGGAGGGTATTGTCCCTGGTGGCGGTACTACTTTGATTCACTTGTCTACTAAAGTGGAGGAGCT
AAAAGGTAGTCTCAATAATGAAGAAGAGAAAATTGGTGCTGATATTGTTAGACGTGCTTTAGAAGCACCTTTAAATCAAA
TTGCTAATAACTCTGGTGTAGAGGGTTCGGTAATTGTAGAAAAAGTACGTTCTACTGATTTTAGTGTTGGTTACAATGTG
ATAACTGGCGAGTACGAAGATCTGATTGCTGCTGGTATTCTTGACCCGGCGATGGTGGTACGTTCTGCGTTGCAAAATGC
GGGTTCTATTGCTGGTATGGTCTTAACTACTGAGGCTGTGGTTGTTGAGAAGCCTGAGAAGAAAGGTGCTGCTCCTGATA
TGGATGGCGGCATGGGCGGCATGGGCGGCATGGGCGGCATGGGCGGCATGGGCGGCATGGGTATGCCTGGTATGGGAATG
ATGTAA

Upstream 100 bases:

>100_bases
TAATTTGTGACTTTTGACTTTTAAATGTACGGTTTCCACTAACTAGCACTCTATTGTATAGAGTGCTAAATTTTTATTTG
GAAGTAATAGGAAAAAGTAT

Downstream 100 bases:

>100_bases
TTTTGCCTATCTACCTAAAGTCAATGTATCAGTTAGTCTGTTTATGGAGGGCTAATAGGGGTAATTGGCAATAAAAAATT
AATGACATCAGGTTAGACAT

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MAKIVEFDDKSRRSLERGINTLADAVRITMGPKGRNVLLEKKYGAPQIVNDGITVAKDIELEDPLENTGAKLIQEVASKT
KDIAGDGTTTATVLAQSMIKEGLKNVAAGANPVAVRRGIEKTVSLLVKEIQTVAKPVEGEAIAQVATVSAGGDAEVGRMI
SEAMDKVTKDGVITVEESKSLSTDLEVVEGMQIDRGYLSPYFVTDQERLVVDFENARILITDKKISSIQDLVPVLEKVAR
AGQSLLIIAEDIEGEALATLVVNKARGVLNVAAVKAPGFGDRRKAMLQDIAILTGGQLISEEVGLSLEMVDLDMMGIGRK
ISINKDNTTIVADGGTAEEVKKRIAQIRKQLGESDSDYDKEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNA
TKAAVEEGIVPGGGTTLIHLSTKVEELKGSLNNEEEKIGADIVRRALEAPLNQIANNSGVEGSVIVEKVRSTDFSVGYNV
ITGEYEDLIAAGILDPAMVVRSALQNAGSIAGMVLTTEAVVVEKPEKKGAAPDMDGGMGGMGGMGGMGGMGGMGMPGMGM
M

Sequences:

>Translated_561_residues
MAKIVEFDDKSRRSLERGINTLADAVRITMGPKGRNVLLEKKYGAPQIVNDGITVAKDIELEDPLENTGAKLIQEVASKT
KDIAGDGTTTATVLAQSMIKEGLKNVAAGANPVAVRRGIEKTVSLLVKEIQTVAKPVEGEAIAQVATVSAGGDAEVGRMI
SEAMDKVTKDGVITVEESKSLSTDLEVVEGMQIDRGYLSPYFVTDQERLVVDFENARILITDKKISSIQDLVPVLEKVAR
AGQSLLIIAEDIEGEALATLVVNKARGVLNVAAVKAPGFGDRRKAMLQDIAILTGGQLISEEVGLSLEMVDLDMMGIGRK
ISINKDNTTIVADGGTAEEVKKRIAQIRKQLGESDSDYDKEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNA
TKAAVEEGIVPGGGTTLIHLSTKVEELKGSLNNEEEKIGADIVRRALEAPLNQIANNSGVEGSVIVEKVRSTDFSVGYNV
ITGEYEDLIAAGILDPAMVVRSALQNAGSIAGMVLTTEAVVVEKPEKKGAAPDMDGGMGGMGGMGGMGGMGGMGMPGMGM
M
>Mature_560_residues
AKIVEFDDKSRRSLERGINTLADAVRITMGPKGRNVLLEKKYGAPQIVNDGITVAKDIELEDPLENTGAKLIQEVASKTK
DIAGDGTTTATVLAQSMIKEGLKNVAAGANPVAVRRGIEKTVSLLVKEIQTVAKPVEGEAIAQVATVSAGGDAEVGRMIS
EAMDKVTKDGVITVEESKSLSTDLEVVEGMQIDRGYLSPYFVTDQERLVVDFENARILITDKKISSIQDLVPVLEKVARA
GQSLLIIAEDIEGEALATLVVNKARGVLNVAAVKAPGFGDRRKAMLQDIAILTGGQLISEEVGLSLEMVDLDMMGIGRKI
SINKDNTTIVADGGTAEEVKKRIAQIRKQLGESDSDYDKEKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNAT
KAAVEEGIVPGGGTTLIHLSTKVEELKGSLNNEEEKIGADIVRRALEAPLNQIANNSGVEGSVIVEKVRSTDFSVGYNVI
TGEYEDLIAAGILDPAMVVRSALQNAGSIAGMVLTTEAVVVEKPEKKGAAPDMDGGMGGMGGMGGMGGMGGMGMPGMGMM

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family

Homologues:

Organism=Homo sapiens, GI41399285, Length=531, Percent_Identity=47.834274952919, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI31542947, Length=531, Percent_Identity=47.834274952919, Blast_Score=486, Evalue=1e-137,
Organism=Escherichia coli, GI1790586, Length=530, Percent_Identity=57.7358490566038, Blast_Score=600, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17555558, Length=531, Percent_Identity=47.2693032015066, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI193210679, Length=224, Percent_Identity=43.75, Blast_Score=188, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323288, Length=532, Percent_Identity=49.812030075188, Blast_Score=499, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24641193, Length=530, Percent_Identity=49.622641509434, Blast_Score=503, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24641191, Length=530, Percent_Identity=49.622641509434, Blast_Score=503, Evalue=1e-143,
Organism=Drosophila melanogaster, GI45550936, Length=527, Percent_Identity=47.8178368121442, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI45550132, Length=527, Percent_Identity=47.8178368121442, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI45550935, Length=527, Percent_Identity=47.8178368121442, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI17864606, Length=553, Percent_Identity=41.5913200723327, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24584129, Length=532, Percent_Identity=33.8345864661654, Blast_Score=278, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19921262, Length=532, Percent_Identity=33.8345864661654, Blast_Score=278, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24645179, Length=536, Percent_Identity=21.6417910447761, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): CH601_TRIEI (Q119S1)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720226.1
- ProteinModelPortal:   Q119S1
- SMR:   Q119S1
- STRING:   Q119S1
- GeneID:   4241637
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0270
- NMPDR:   fig|203124.1.peg.2563
- eggNOG:   COG0459
- HOGENOM:   HBG625289
- OMA:   NKPETAT
- ProtClustDB:   PRK12849
- BioCyc:   TERY203124:TERY_0270-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00600
- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423
- PANTHER:   PTHR11353
- PRINTS:   PR00298
- TIGRFAMs:   TIGR02348

Pfam domain/function: PF00118 Cpn60_TCP1; SSF48592 GroEL-ATPase

EC number: NA

Molecular weight: Translated: 59164; Mature: 59033

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVEFDDKSRRSLERGINTLADAVRITMGPKGRNVLLEKKYGAPQIVNDGITVAKDIE
CCCEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCEECCCCEEEECCC
LEDPLENTGAKLIQEVASKTKDIAGDGTTTATVLAQSMIKEGLKNVAAGANPVAVRRGIE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KTVSLLVKEIQTVAKPVEGEAIAQVATVSAGGDAEVGRMISEAMDKVTKDGVITVEESKS
HHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
LSTDLEVVEGMQIDRGYLSPYFVTDQERLVVDFENARILITDKKISSIQDLVPVLEKVAR
CHHHHHHHCCCEECCCCCCCEEECCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
AGQSLLIIAEDIEGEALATLVVNKARGVLNVAAVKAPGFGDRRKAMLQDIAILTGGQLIS
CCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHH
EEVGLSLEMVDLDMMGIGRKISINKDNTTIVADGGTAEEVKKRIAQIRKQLGESDSDYDK
HHHCCEEEEEEEHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCH
EKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNATKAAVEEGIVPGGGTTLIHL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
STKVEELKGSLNNEEEKIGADIVRRALEAPLNQIANNSGVEGSVIVEKVRSTDFSVGYNV
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEE
ITGEYEDLIAAGILDPAMVVRSALQNAGSIAGMVLTTEAVVVEKPEKKGAAPDMDGGMGG
ECCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECEEEEECCHHCCCCCCCCCCCCC
MGGMGGMGGMGGMGMPGMGMM
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKIVEFDDKSRRSLERGINTLADAVRITMGPKGRNVLLEKKYGAPQIVNDGITVAKDIE
CCEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCEECCCCEEEECCC
LEDPLENTGAKLIQEVASKTKDIAGDGTTTATVLAQSMIKEGLKNVAAGANPVAVRRGIE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KTVSLLVKEIQTVAKPVEGEAIAQVATVSAGGDAEVGRMISEAMDKVTKDGVITVEESKS
HHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
LSTDLEVVEGMQIDRGYLSPYFVTDQERLVVDFENARILITDKKISSIQDLVPVLEKVAR
CHHHHHHHCCCEECCCCCCCEEECCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
AGQSLLIIAEDIEGEALATLVVNKARGVLNVAAVKAPGFGDRRKAMLQDIAILTGGQLIS
CCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHH
EEVGLSLEMVDLDMMGIGRKISINKDNTTIVADGGTAEEVKKRIAQIRKQLGESDSDYDK
HHHCCEEEEEEEHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCH
EKLQERIAKLAGGVAVIKVGAATETELKDRKLRIEDALNATKAAVEEGIVPGGGTTLIHL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
STKVEELKGSLNNEEEKIGADIVRRALEAPLNQIANNSGVEGSVIVEKVRSTDFSVGYNV
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEE
ITGEYEDLIAAGILDPAMVVRSALQNAGSIAGMVLTTEAVVVEKPEKKGAAPDMDGGMGG
ECCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECEEEEECCHHCCCCCCCCCCCCC
MGGMGGMGGMGGMGMPGMGMM
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA