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The map label for this gene is ltrA [H]

Identifier: 113474138

GI number: 113474138

Start: 373560

End: 375467

Strand: Direct

Name: ltrA [H]

Synonym: Tery_0239

Alternate gene names: 113474138

Gene position: 373560-375467 (Clockwise)

Preceding gene: 113474133

Following gene: 113474142

Centisome position: 4.82

GC content: 39.26

Gene sequence:

>1908_bases
ATGAATAAAGCTGAAATACTAAAAAGAAAATTGGACAATCCAAGGCCCTTTTCAAGTGTGGCATGGGACACGTACGATAT
ACCTAACCAGGTTTGTGTTAATCCCAATCTCAAATGGAAAGACATCAACTGGAAAAAGGTAGAAAAGTATGTGTTTAAGT
TACAAAAGTTAATCTATAGAGCATCCAGCCGTGGCGAAATCCGCAAAATGCGTAAATACCAAAAACTTCTGACCAAAAGT
TATTATGCAAGGTTGCTAGCTGTTAGGCGTGTGACTCAGGACAACCAAGGAAAGAAAACTGCTGGTATAGATGGTATAAA
AAGCCTTCCCCCAATGCAGAGGTTGAACCTGGTAGAAATGTTAGGGTCACGATTTCTTAAAGCAAGCCCAATCCGTAGAG
TCTGGATACCAAAACCAGGTAGAGAAGAAAAACGTCCACTAGGCATACCCACTATGTATGATAGGGCACTTCAAGCACTG
GTAAAGTTAGGCATGGAACCAGAATGGGAAGCACTTTTTGAACCTAATAGTTATGGTTTTAGACCAGGACGGTCAACATA
CGATGCTATTGCAGCAATCTATGTCAGTATTAACCACAAACCAAAATATGTTTTAGATGCTGACATATCCAAATGTTTTG
ACCGAATTAACCATGATGCACTGTTGGGAAAAATAGGAAAATCCCCATATAGAAAATTAGTTAAACAATGGCTAAAATCC
GGGGTATTTGACAATAAACAATTCTCAAACACTGTGGAAGGTACACCACAGGGAGGGGTAATATCACCCTTGCTAGCAAA
CATCGCCCTACACGGTATGGAAAAATGCCTAGAAGATTATGCAGAAACCCTCCCAGGGACAAAGCGTGATAATCAAAGAG
CATTATCCTTAATACGATATGCCGATGACTTTGTAATCCTACATAAAGACATCAAAGTATTGTTACAAGCAAAAACTGTA
ATACAGGAATGGTTAAACCAAGTAGGGTTAGAACTAAAACCAGAAAAAACCAAAATTGCCCACACTCTGGAAGAATATGA
AGGAAATAAACCCGGATTTGACTTTCTAGGATTTACAATAAGGCAATGGAAAGGTAAGACAACCAAACAAGGATTCAAAA
CACTGATTAAGCCATCATCTAAGAGTATTAAAACTCATTATCGGAAGCTGGCGGATATAGGTGACACCTACAAAACCGTC
CCTACAAAAGCTCTAATAGCTAAACTTAATCCGGTAATTAGAGGATGGGCCAACTACTTTTCCACCGTAGTCAGTAAAGA
GGTATATAATAAATTAGACTACCTTCTATGGGAAAGATTAGGTCGATGGGCAAGTAGACGGCATCCAAACAAGTCAGCCA
AATGGGTCAAGAATAAGTATTTTCCTCGCTGCAAAGTCACCAGAAACTGGTTACTTAACGACGGCGAATATATACTTAAC
CAACACTCAGACGCTGCCATAAAAAGGCACGTCAAGGTAAAAGGCAATAAATCCCCATTAGACGGTGATTTGACTTATTG
GAGTAGTAGAATCGGCAAACACCCAGGTGTAAGGAAAGAAGTCACAACGCTGTTAAAACGGCAAAAGAATAAATGCGCAT
TTTGTGGACTAACCTTTAGATCAAATGACCTCATGGAAATAGACCATATAAAACCAAAGTCTGAAGGCGGTGATAACTCA
ATTAAAAACAAGCAACTGTTACACCGACATTGCCACGATACTAAAACTGCTTTAGATAATAAAACATACACAAAACCTAA
GTTACAGGATTTACCTGATGAATACCTATGGGTAAATGATATGTTAATTCTAAAACAGGGATGTACCTATGAAAAAGGAC
GTTTAGGAGAGAAGCCGGATGAGGTGAAAGTCTCACGTCCGGTTTTGAAGACGAGTCGGGTAAGGTAA

Upstream 100 bases:

>100_bases
TCTACACAAAGTTGTAGGTTTTAAGGAGAGTAGGATTGAGTAAGAAGCATATTATGCAGACGTACTCACTGTTAGACGTA
ATATAGAGTAATGATTAGTC

Downstream 100 bases:

>100_bases
CTTACCTGGCGAATGTTTAACTTTACTTCAGTTGTGGGCTAACCTGATACCGGACTAGAAAATTTTAAACTTTTGTTGAA
TGTCCAATTATCCACATACC

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MNKAEILKRKLDNPRPFSSVAWDTYDIPNQVCVNPNLKWKDINWKKVEKYVFKLQKLIYRASSRGEIRKMRKYQKLLTKS
YYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRLNLVEMLGSRFLKASPIRRVWIPKPGREEKRPLGIPTMYDRALQAL
VKLGMEPEWEALFEPNSYGFRPGRSTYDAIAAIYVSINHKPKYVLDADISKCFDRINHDALLGKIGKSPYRKLVKQWLKS
GVFDNKQFSNTVEGTPQGGVISPLLANIALHGMEKCLEDYAETLPGTKRDNQRALSLIRYADDFVILHKDIKVLLQAKTV
IQEWLNQVGLELKPEKTKIAHTLEEYEGNKPGFDFLGFTIRQWKGKTTKQGFKTLIKPSSKSIKTHYRKLADIGDTYKTV
PTKALIAKLNPVIRGWANYFSTVVSKEVYNKLDYLLWERLGRWASRRHPNKSAKWVKNKYFPRCKVTRNWLLNDGEYILN
QHSDAAIKRHVKVKGNKSPLDGDLTYWSSRIGKHPGVRKEVTTLLKRQKNKCAFCGLTFRSNDLMEIDHIKPKSEGGDNS
IKNKQLLHRHCHDTKTALDNKTYTKPKLQDLPDEYLWVNDMLILKQGCTYEKGRLGEKPDEVKVSRPVLKTSRVR

Sequences:

>Translated_635_residues
MNKAEILKRKLDNPRPFSSVAWDTYDIPNQVCVNPNLKWKDINWKKVEKYVFKLQKLIYRASSRGEIRKMRKYQKLLTKS
YYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRLNLVEMLGSRFLKASPIRRVWIPKPGREEKRPLGIPTMYDRALQAL
VKLGMEPEWEALFEPNSYGFRPGRSTYDAIAAIYVSINHKPKYVLDADISKCFDRINHDALLGKIGKSPYRKLVKQWLKS
GVFDNKQFSNTVEGTPQGGVISPLLANIALHGMEKCLEDYAETLPGTKRDNQRALSLIRYADDFVILHKDIKVLLQAKTV
IQEWLNQVGLELKPEKTKIAHTLEEYEGNKPGFDFLGFTIRQWKGKTTKQGFKTLIKPSSKSIKTHYRKLADIGDTYKTV
PTKALIAKLNPVIRGWANYFSTVVSKEVYNKLDYLLWERLGRWASRRHPNKSAKWVKNKYFPRCKVTRNWLLNDGEYILN
QHSDAAIKRHVKVKGNKSPLDGDLTYWSSRIGKHPGVRKEVTTLLKRQKNKCAFCGLTFRSNDLMEIDHIKPKSEGGDNS
IKNKQLLHRHCHDTKTALDNKTYTKPKLQDLPDEYLWVNDMLILKQGCTYEKGRLGEKPDEVKVSRPVLKTSRVR
>Mature_635_residues
MNKAEILKRKLDNPRPFSSVAWDTYDIPNQVCVNPNLKWKDINWKKVEKYVFKLQKLIYRASSRGEIRKMRKYQKLLTKS
YYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRLNLVEMLGSRFLKASPIRRVWIPKPGREEKRPLGIPTMYDRALQAL
VKLGMEPEWEALFEPNSYGFRPGRSTYDAIAAIYVSINHKPKYVLDADISKCFDRINHDALLGKIGKSPYRKLVKQWLKS
GVFDNKQFSNTVEGTPQGGVISPLLANIALHGMEKCLEDYAETLPGTKRDNQRALSLIRYADDFVILHKDIKVLLQAKTV
IQEWLNQVGLELKPEKTKIAHTLEEYEGNKPGFDFLGFTIRQWKGKTTKQGFKTLIKPSSKSIKTHYRKLADIGDTYKTV
PTKALIAKLNPVIRGWANYFSTVVSKEVYNKLDYLLWERLGRWASRRHPNKSAKWVKNKYFPRCKVTRNWLLNDGEYILN
QHSDAAIKRHVKVKGNKSPLDGDLTYWSSRIGKHPGVRKEVTTLLKRQKNKCAFCGLTFRSNDLMEIDHIKPKSEGGDNS
IKNKQLLHRHCHDTKTALDNKTYTKPKLQDLPDEYLWVNDMLILKQGCTYEKGRLGEKPDEVKVSRPVLKTSRVR

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226521, Length=373, Percent_Identity=25.4691689008043, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6226520, Length=331, Percent_Identity=26.8882175226586, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 73380; Mature: 73380

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAEILKRKLDNPRPFSSVAWDTYDIPNQVCVNPNLKWKDINWKKVEKYVFKLQKLIYR
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCEECCCCHHHHHHHHHHHHHHHHH
ASSRGEIRKMRKYQKLLTKSYYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRLNLVEM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHH
LGSRFLKASPIRRVWIPKPGREEKRPLGIPTMYDRALQALVKLGMEPEWEALFEPNSYGF
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
RPGRSTYDAIAAIYVSINHKPKYVLDADISKCFDRINHDALLGKIGKSPYRKLVKQWLKS
CCCCCHHHHHHHHEEEECCCCCEEEECHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHC
GVFDNKQFSNTVEGTPQGGVISPLLANIALHGMEKCLEDYAETLPGTKRDNQRALSLIRY
CCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ADDFVILHKDIKVLLQAKTVIQEWLNQVGLELKPEKTKIAHTLEEYEGNKPGFDFLGFTI
HCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCCCHHHHHHH
RQWKGKTTKQGFKTLIKPSSKSIKTHYRKLADIGDTYKTVPTKALIAKLNPVIRGWANYF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STVVSKEVYNKLDYLLWERLGRWASRRHPNKSAKWVKNKYFPRCKVTRNWLLNDGEYILN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHC
QHSDAAIKRHVKVKGNKSPLDGDLTYWSSRIGKHPGVRKEVTTLLKRQKNKCAFCGLTFR
CCCHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEC
SNDLMEIDHIKPKSEGGDNSIKNKQLLHRHCHDTKTALDNKTYTKPKLQDLPDEYLWVND
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHEEHHC
MLILKQGCTYEKGRLGEKPDEVKVSRPVLKTSRVR
CCEECCCCCCCCCCCCCCCCCCCHHCCHHHHCCCC
>Mature Secondary Structure
MNKAEILKRKLDNPRPFSSVAWDTYDIPNQVCVNPNLKWKDINWKKVEKYVFKLQKLIYR
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCEECCCCHHHHHHHHHHHHHHHHH
ASSRGEIRKMRKYQKLLTKSYYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRLNLVEM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHH
LGSRFLKASPIRRVWIPKPGREEKRPLGIPTMYDRALQALVKLGMEPEWEALFEPNSYGF
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
RPGRSTYDAIAAIYVSINHKPKYVLDADISKCFDRINHDALLGKIGKSPYRKLVKQWLKS
CCCCCHHHHHHHHEEEECCCCCEEEECHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHC
GVFDNKQFSNTVEGTPQGGVISPLLANIALHGMEKCLEDYAETLPGTKRDNQRALSLIRY
CCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ADDFVILHKDIKVLLQAKTVIQEWLNQVGLELKPEKTKIAHTLEEYEGNKPGFDFLGFTI
HCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCCCHHHHHHH
RQWKGKTTKQGFKTLIKPSSKSIKTHYRKLADIGDTYKTVPTKALIAKLNPVIRGWANYF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STVVSKEVYNKLDYLLWERLGRWASRRHPNKSAKWVKNKYFPRCKVTRNWLLNDGEYILN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHC
QHSDAAIKRHVKVKGNKSPLDGDLTYWSSRIGKHPGVRKEVTTLLKRQKNKCAFCGLTFR
CCCHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEC
SNDLMEIDHIKPKSEGGDNSIKNKQLLHRHCHDTKTALDNKTYTKPKLQDLPDEYLWVND
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHEEHHC
MLILKQGCTYEKGRLGEKPDEVKVSRPVLKTSRVR
CCEECCCCCCCCCCCCCCCCCCCHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]