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The map label for this gene is yrbG [H]

Identifier: 110835490

GI number: 110835490

Start: 2975138

End: 2976121

Strand: Reverse

Name: yrbG [H]

Synonym: ABO_2629

Alternate gene names: 110835490

Gene position: 2976121-2975138 (Counterclockwise)

Preceding gene: 110835491

Following gene: 110835489

Centisome position: 95.38

GC content: 56.91

Gene sequence:

>984_bases
GTGCCGATGTTGCTGGCCATTGCCGCCGTGATTGGCGGGCTGATACTGCTGGTATGGAGTGCGGACAAATTTGTCGAAGG
GGCGGCGGGTACGGCGGTTCATGCCGGTATGCCGCCTCTGTTAATCGGTATGCTGATTGTGGGCTTTGGTACGTCTGCCC
CGGAGATGGTGGTGTCGGCGCTGGCGGCGCTGGAAGGCAACCCGTCTCTGGCGTTAGGTAATGCCTACGGGTCGAATATT
TCTAACATCGCCCTCATTCTAGGGGTAGTGGCGGTAATGAGCCCGATTCTGGTGAATTCCGCTATTCTCAAGAAAGAGCT
ACCGATTCTCACACTGATTACCCTACTGTCGGGCTATCAGCTCATCGATGGACACATTTCTCGCCTAGACGCCTGGGTGC
TGATTGGGGTGTTGGCGGTACTGATGGGCTGGTCTATTTATGCGGCGATGACGGGCAAAGCCGATGTGCTCGCCGGAGAA
GTGGAGACGGATCTGGCAGAGCACCCGCTGCCGTTGAAGAAAGCGTTGCTATGGTTGGTGGTGGGGTTGATTCTGCTGGT
GGTCAGCTCTCGGGCGCTGGTGTGGGGCGCAGTCTTGATTGCCCAGTCCTTGGGCGTCAGCGATTTGATCATTGGCCTTA
CTATCGTTGCTCTTGGCACCTCTTTGCCGGAACTGGCTTCCAGCATTGCGGCGGTGCGCAAGGGCGAACACGATATAGCC
TTTGGTAACGTGCTAGGCTCGAATTTGTTCAATACGTTGGCGGTGGTCGGTATCGCCGGCGCCATCAAACCCATGACTGT
GGATGCAGGCGTTTTGCAGCGCGACTGGTCTCTAATGATGGGGCTGACGCTGATGCTGTTCGTCATGGGTTTCGGCCTGT
GGGGCCGTAAGGGCCAAATAACCCGAGCTAACGGCGTTGGTTTGCTGGTGGTTTATGTGGCATACATGGGTTATCTGGGG
TCTACCATGCTGGGGGGCGGTTGA

Upstream 100 bases:

>100_bases
CGTGATGCGGGTTGCATCTATGTAGGTGCCAGCCTCGCTCCTCTCTGCCACAATGTGCCCGCCTGAGATGATTATCATCC
TGAATTGATGACCCCAAGGA

Downstream 100 bases:

>100_bases
CCTCGCTTGGGCTCGGACGGACGGCTTCGGTTTTATCCGAATGACGAGAGATAAGGAGGCGGCAGGGTATGCGGGACTCG
GGAATATTGGAAAAACTGGA

Product: Ca2+/Na+antiporter protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPMLLAIAAVIGGLILLVWSADKFVEGAAGTAVHAGMPPLLIGMLIVGFGTSAPEMVVSALAALEGNPSLALGNAYGSNI
SNIALILGVVAVMSPILVNSAILKKELPILTLITLLSGYQLIDGHISRLDAWVLIGVLAVLMGWSIYAAMTGKADVLAGE
VETDLAEHPLPLKKALLWLVVGLILLVVSSRALVWGAVLIAQSLGVSDLIIGLTIVALGTSLPELASSIAAVRKGEHDIA
FGNVLGSNLFNTLAVVGIAGAIKPMTVDAGVLQRDWSLMMGLTLMLFVMGFGLWGRKGQITRANGVGLLVVYVAYMGYLG
STMLGGG

Sequences:

>Translated_327_residues
MPMLLAIAAVIGGLILLVWSADKFVEGAAGTAVHAGMPPLLIGMLIVGFGTSAPEMVVSALAALEGNPSLALGNAYGSNI
SNIALILGVVAVMSPILVNSAILKKELPILTLITLLSGYQLIDGHISRLDAWVLIGVLAVLMGWSIYAAMTGKADVLAGE
VETDLAEHPLPLKKALLWLVVGLILLVVSSRALVWGAVLIAQSLGVSDLIIGLTIVALGTSLPELASSIAAVRKGEHDIA
FGNVLGSNLFNTLAVVGIAGAIKPMTVDAGVLQRDWSLMMGLTLMLFVMGFGLWGRKGQITRANGVGLLVVYVAYMGYLG
STMLGGG
>Mature_326_residues
PMLLAIAAVIGGLILLVWSADKFVEGAAGTAVHAGMPPLLIGMLIVGFGTSAPEMVVSALAALEGNPSLALGNAYGSNIS
NIALILGVVAVMSPILVNSAILKKELPILTLITLLSGYQLIDGHISRLDAWVLIGVLAVLMGWSIYAAMTGKADVLAGEV
ETDLAEHPLPLKKALLWLVVGLILLVVSSRALVWGAVLIAQSLGVSDLIIGLTIVALGTSLPELASSIAAVRKGEHDIAF
GNVLGSNLFNTLAVVGIAGAIKPMTVDAGVLQRDWSLMMGLTLMLFVMGFGLWGRKGQITRANGVGLLVVYVAYMGYLGS
TMLGGG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI31563526, Length=134, Percent_Identity=33.5820895522388, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789587, Length=322, Percent_Identity=40.3726708074534, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33713; Mature: 33582

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLLAIAAVIGGLILLVWSADKFVEGAAGTAVHAGMPPLLIGMLIVGFGTSAPEMVVSA
CHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHH
LAALEGNPSLALGNAYGSNISNIALILGVVAVMSPILVNSAILKKELPILTLITLLSGYQ
HHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
LIDGHISRLDAWVLIGVLAVLMGWSIYAAMTGKADVLAGEVETDLAEHPLPLKKALLWLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCCHHHHHHHHH
VGLILLVVSSRALVWGAVLIAQSLGVSDLIIGLTIVALGTSLPELASSIAAVRKGEHDIA
HHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
FGNVLGSNLFNTLAVVGIAGAIKPMTVDAGVLQRDWSLMMGLTLMLFVMGFGLWGRKGQI
HHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
TRANGVGLLVVYVAYMGYLGSTMLGGG
EECCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PMLLAIAAVIGGLILLVWSADKFVEGAAGTAVHAGMPPLLIGMLIVGFGTSAPEMVVSA
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHH
LAALEGNPSLALGNAYGSNISNIALILGVVAVMSPILVNSAILKKELPILTLITLLSGYQ
HHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
LIDGHISRLDAWVLIGVLAVLMGWSIYAAMTGKADVLAGEVETDLAEHPLPLKKALLWLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCCHHHHHHHHH
VGLILLVVSSRALVWGAVLIAQSLGVSDLIIGLTIVALGTSLPELASSIAAVRKGEHDIA
HHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
FGNVLGSNLFNTLAVVGIAGAIKPMTVDAGVLQRDWSLMMGLTLMLFVMGFGLWGRKGQI
HHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
TRANGVGLLVVYVAYMGYLGSTMLGGG
EECCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]