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The map label for this gene is fda [H]

Identifier: 110835473

GI number: 110835473

Start: 2954511

End: 2955575

Strand: Reverse

Name: fda [H]

Synonym: ABO_2612

Alternate gene names: 110835473

Gene position: 2955575-2954511 (Counterclockwise)

Preceding gene: 110835474

Following gene: 110835471

Centisome position: 94.73

GC content: 53.9

Gene sequence:

>1065_bases
ATGGCACTAGTAAGCATGCGACAGCTGCTGGACCACGCTGCCGAGTTCGGCTACGGCGTACCGGCTTATAATGTGAACAA
TGTGGAACAAATGCGCGCCATTATGGAAGCCGCGGACAAAACCAACTCCCCGGTGATCGTGCAGGCGTCTGCTGGAGCCC
GCAAATATGCAGGTGCGCCTTTCTTGCGTCATCTGATTCTGGCGGCCACCGAAGAGTTTCCACATATTCCTGTCGTTATG
CATCAGGACCATGGCACCAGCCCGTCTGTTTGCCAGCGCTCTATTCAGCTGGGCTTCTCCTCGGTGATGATGGATGGGTC
CTTGGGTGAAGATGGCAAAACCCCCACCGATTACGAGTACAACGTGGAGGTAACTCGCCGCACTGTGGACATGGCGCATG
CTTGTGGTGTGTCTGTTGAGGGTGAGCTGGGTTGTCTGGGTTCTTTGGAAACCGGTGAAGCCGGTGAAGAAGACGGTATT
GGTGCGGCCGGCAAGCTAACCCACGAGCAGATGCTGACCGACCCTGAAGAAGCGGCTGACTTTGTGCAGAAAACCAAAGT
GGATGCCCTGGCGATTGCTATCGGTACCAGCCACGGGGCCTATAAATTCACTCGCCCACCCACCGGGGATATTCTGGCCA
TCGAGCAGATTAAAGCGATCCATAAACGCATTCCGGATACCCACTTGGTGATGCACGGCTCTTCTTCCGTGCCGCAGGAC
TGGTTGGCGATCATTAATGAATTTGGTGGTGAAATTCCGGAAACCTACGGTGTGCCGGTGGAAGAAATTCAGGAAGGCAT
CAAGCACGGTGTGCGTAAGGTCAACATCGATACCGACTTGCGGTTGGCGTCCACCGGGGCAATCCGTCGCTTCCTGGCCC
AGAACCCAGCCGAGTTTGATCCACGTAAATACCTGAAAGAATCCATCACTGCCATGCGAGATATCTGTATGGCCCGTTAT
GAAGCTTTTGGTACGGCGGGTTATGCGGACAAGATCAAACCGATCAGCTTAGAAAAGATGTTCCAGCGTTATGAATCCGG
TGATTTGGATCCACGGGTTAAATAA

Upstream 100 bases:

>100_bases
CAACTCGTACGTTAGGCGTTTGGTTTTTGACATCGGGTTGTAATGGACGAAGCATAGGCGGTGCGCGCGCATCGCAAACG
GATAATGAAGGGGAAATACC

Downstream 100 bases:

>100_bases
ACGTCGCCGAACGCTTTCGGTTATAGGCCGCACGCGGATCGACAAAAAAACCGCGCCCAACCGGGCGCGGTTTTTTTGTG
TATCGCTACATTAGCGAGTG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MALVSMRQLLDHAAEFGYGVPAYNVNNVEQMRAIMEAADKTNSPVIVQASAGARKYAGAPFLRHLILAATEEFPHIPVVM
HQDHGTSPSVCQRSIQLGFSSVMMDGSLGEDGKTPTDYEYNVEVTRRTVDMAHACGVSVEGELGCLGSLETGEAGEEDGI
GAAGKLTHEQMLTDPEEAADFVQKTKVDALAIAIGTSHGAYKFTRPPTGDILAIEQIKAIHKRIPDTHLVMHGSSSVPQD
WLAIINEFGGEIPETYGVPVEEIQEGIKHGVRKVNIDTDLRLASTGAIRRFLAQNPAEFDPRKYLKESITAMRDICMARY
EAFGTAGYADKIKPISLEKMFQRYESGDLDPRVK

Sequences:

>Translated_354_residues
MALVSMRQLLDHAAEFGYGVPAYNVNNVEQMRAIMEAADKTNSPVIVQASAGARKYAGAPFLRHLILAATEEFPHIPVVM
HQDHGTSPSVCQRSIQLGFSSVMMDGSLGEDGKTPTDYEYNVEVTRRTVDMAHACGVSVEGELGCLGSLETGEAGEEDGI
GAAGKLTHEQMLTDPEEAADFVQKTKVDALAIAIGTSHGAYKFTRPPTGDILAIEQIKAIHKRIPDTHLVMHGSSSVPQD
WLAIINEFGGEIPETYGVPVEEIQEGIKHGVRKVNIDTDLRLASTGAIRRFLAQNPAEFDPRKYLKESITAMRDICMARY
EAFGTAGYADKIKPISLEKMFQRYESGDLDPRVK
>Mature_353_residues
ALVSMRQLLDHAAEFGYGVPAYNVNNVEQMRAIMEAADKTNSPVIVQASAGARKYAGAPFLRHLILAATEEFPHIPVVMH
QDHGTSPSVCQRSIQLGFSSVMMDGSLGEDGKTPTDYEYNVEVTRRTVDMAHACGVSVEGELGCLGSLETGEAGEEDGIG
AAGKLTHEQMLTDPEEAADFVQKTKVDALAIAIGTSHGAYKFTRPPTGDILAIEQIKAIHKRIPDTHLVMHGSSSVPQDW
LAIINEFGGEIPETYGVPVEEIQEGIKHGVRKVNIDTDLRLASTGAIRRFLAQNPAEFDPRKYLKESITAMRDICMARYE
AFGTAGYADKIKPISLEKMFQRYESGDLDPRVK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=327, Percent_Identity=32.4159021406728, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082041, Length=315, Percent_Identity=32.3809523809524, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788072, Length=329, Percent_Identity=27.355623100304, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38633; Mature: 38502

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVSMRQLLDHAAEFGYGVPAYNVNNVEQMRAIMEAADKTNSPVIVQASAGARKYAGAP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCCH
FLRHLILAATEEFPHIPVVMHQDHGTSPSVCQRSIQLGFSSVMMDGSLGEDGKTPTDYEY
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
NVEVTRRTVDMAHACGVSVEGELGCLGSLETGEAGEEDGIGAAGKLTHEQMLTDPEEAAD
EEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHH
FVQKTKVDALAIAIGTSHGAYKFTRPPTGDILAIEQIKAIHKRIPDTHLVMHGSSSVPQD
HHHHHHHCEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCCHH
WLAIINEFGGEIPETYGVPVEEIQEGIKHGVRKVNIDTDLRLASTGAIRRFLAQNPAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYLKESITAMRDICMARYEAFGTAGYADKIKPISLEKMFQRYESGDLDPRVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALVSMRQLLDHAAEFGYGVPAYNVNNVEQMRAIMEAADKTNSPVIVQASAGARKYAGAP
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCCH
FLRHLILAATEEFPHIPVVMHQDHGTSPSVCQRSIQLGFSSVMMDGSLGEDGKTPTDYEY
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
NVEVTRRTVDMAHACGVSVEGELGCLGSLETGEAGEEDGIGAAGKLTHEQMLTDPEEAAD
EEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHH
FVQKTKVDALAIAIGTSHGAYKFTRPPTGDILAIEQIKAIHKRIPDTHLVMHGSSSVPQD
HHHHHHHCEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCCHH
WLAIINEFGGEIPETYGVPVEEIQEGIKHGVRKVNIDTDLRLASTGAIRRFLAQNPAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYLKESITAMRDICMARYEAFGTAGYADKIKPISLEKMFQRYESGDLDPRVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]