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The map label for this gene is ubiH [H]

Identifier: 110835460

GI number: 110835460

Start: 2943040

End: 2944176

Strand: Reverse

Name: ubiH [H]

Synonym: ABO_2599

Alternate gene names: 110835460

Gene position: 2944176-2943040 (Counterclockwise)

Preceding gene: 110835461

Following gene: 110835459

Centisome position: 94.36

GC content: 60.86

Gene sequence:

>1137_bases
ATGGCCGGTGCTTTGCTGGCGCTATTGTTGCGCCATCATGGGGCGGGCAGAGTGGTGTTAGTCGAAAACCACCCGTTGTC
GTTGCCAGAGTCCCCGCCGTTCACTCCTAGTTTTGATGCCCGTAGTACGGCCTTGTCCGCAGGCACTTTGTCGGTGTTGG
GTGATCTTGGGCTGGCGGACGCCATTCGCGAGCACGCCGCTGCCATTGATACGGTACATGTGTCACGACAATCCCGGCTT
GGCATTACCCGCATATCCGCCCATGAAGAGGGCGTGGATCAGTTGGGCGCAGTAGTCGAAAACCGCTGGCTGGGGTTTGT
GCTGCTCGGCGCCTTGTTTGCGGATAAGAGCATTCAAGTGCGGGCACCGGAAACACTGTCTAGTATTTGTCGTGTTGAAG
GTGGCTATCAGGTGAGCCTGGCCGGTGGTGAGGTGCTCGAAACGCCGCTATTGGTCGCCGCCGACGGCGCTCGGTCGAAG
ACCCGGGAGTGGCTGGGGATCAGCGCGCGGGAGCATGACACCGGGCACGATGCGTTGATTGCCAATGTCTCTTTGGCGGC
TGGCCATGAAGGGATCGCTTACGAGCGCTTTTTGAATGATGGCCCCATGGCCTTATTGCCGTTGCCGGATCAGCGTATGG
CGTTGGTGTGGACGGGGCCGCGCGAGCAGGTGGACCGTTGGGTGGCGTTGGAGAATAGCGAAGTGCTGGCACAATTGCAG
GCCCGTTGCCCGGCAGGCGCGCCACGCCTTTCCAGCATCGGCGAGCGCCAGCGTTATCCGCTGGTACTCACCGAGGCCTG
TGCACAGGTGGTGCCTTATGGCGTGGTGGTCGGTAACGCCGCCCATACCTTGCATCCGGTGGCGGGGCAGGGCTTTAACT
TGGCGGTGCGGGATTTGTTGGCACTGGCGCAAACCGTGGGCGGCAATTCAGATCCCGGTAGCTTGGTGACCTTGCAAGCC
TACGCGCAAAAACGGGAAAAGGATCAGGCCATGATCAGCCAGGCGTCTCGTTGGGTGCCAGAACTGTTCCGGCTGCAGCA
CCCGCTTTTTGCACACAGCCGCCAGCTGGGGCTAGTGGCCATGGATATTTTACCCGGGCTGCGCAGCGGTTTTGCGAAAC
GGGCCATGGGATTGTGA

Upstream 100 bases:

>100_bases
GCTCGCCCTGCATTTTTGCGCCTCAAACGGTGCCCCTATAGCGACAGCGAAAATGGACGTTGGAATGACGCAGCAACCTC
TGGTGATCGTGGGTGGTGGT

Downstream 100 bases:

>100_bases
AAGCACTTAAAAACGTGAGGACAAAGCGTGCATCCCAATAGCGTGTCGTCTGCAAGCGAAAAACAACACATCGTCATCGT
CGGCGGTGGCATGACTGGCG

Product: oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MAGALLALLLRHHGAGRVVLVENHPLSLPESPPFTPSFDARSTALSAGTLSVLGDLGLADAIREHAAAIDTVHVSRQSRL
GITRISAHEEGVDQLGAVVENRWLGFVLLGALFADKSIQVRAPETLSSICRVEGGYQVSLAGGEVLETPLLVAADGARSK
TREWLGISAREHDTGHDALIANVSLAAGHEGIAYERFLNDGPMALLPLPDQRMALVWTGPREQVDRWVALENSEVLAQLQ
ARCPAGAPRLSSIGERQRYPLVLTEACAQVVPYGVVVGNAAHTLHPVAGQGFNLAVRDLLALAQTVGGNSDPGSLVTLQA
YAQKREKDQAMISQASRWVPELFRLQHPLFAHSRQLGLVAMDILPGLRSGFAKRAMGL

Sequences:

>Translated_378_residues
MAGALLALLLRHHGAGRVVLVENHPLSLPESPPFTPSFDARSTALSAGTLSVLGDLGLADAIREHAAAIDTVHVSRQSRL
GITRISAHEEGVDQLGAVVENRWLGFVLLGALFADKSIQVRAPETLSSICRVEGGYQVSLAGGEVLETPLLVAADGARSK
TREWLGISAREHDTGHDALIANVSLAAGHEGIAYERFLNDGPMALLPLPDQRMALVWTGPREQVDRWVALENSEVLAQLQ
ARCPAGAPRLSSIGERQRYPLVLTEACAQVVPYGVVVGNAAHTLHPVAGQGFNLAVRDLLALAQTVGGNSDPGSLVTLQA
YAQKREKDQAMISQASRWVPELFRLQHPLFAHSRQLGLVAMDILPGLRSGFAKRAMGL
>Mature_377_residues
AGALLALLLRHHGAGRVVLVENHPLSLPESPPFTPSFDARSTALSAGTLSVLGDLGLADAIREHAAAIDTVHVSRQSRLG
ITRISAHEEGVDQLGAVVENRWLGFVLLGALFADKSIQVRAPETLSSICRVEGGYQVSLAGGEVLETPLLVAADGARSKT
REWLGISAREHDTGHDALIANVSLAAGHEGIAYERFLNDGPMALLPLPDQRMALVWTGPREQVDRWVALENSEVLAQLQA
RCPAGAPRLSSIGERQRYPLVLTEACAQVVPYGVVVGNAAHTLHPVAGQGFNLAVRDLLALAQTVGGNSDPGSLVTLQAY
AQKREKDQAMISQASRWVPELFRLQHPLFAHSRQLGLVAMDILPGLRSGFAKRAMGL

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=406, Percent_Identity=23.6453201970443, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI32967307, Length=328, Percent_Identity=24.6951219512195, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1789274, Length=383, Percent_Identity=34.7258485639687, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1786883, Length=395, Percent_Identity=30.6329113924051, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789273, Length=344, Percent_Identity=27.3255813953488, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25146631, Length=385, Percent_Identity=24.9350649350649, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 40369; Mature: 40238

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGALLALLLRHHGAGRVVLVENHPLSLPESPPFTPSFDARSTALSAGTLSVLGDLGLAD
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCHHH
AIREHAAAIDTVHVSRQSRLGITRISAHEEGVDQLGAVVENRWLGFVLLGALFADKSIQV
HHHHHHHHHHHHHHCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
RAPETLSSICRVEGGYQVSLAGGEVLETPLLVAADGARSKTREWLGISAREHDTGHDALI
ECCHHHHHHHHCCCCEEEEECCCCHHHCCEEEEECCCCHHHHHHHCCCCCCCCCCCCEEE
ANVSLAAGHEGIAYERFLNDGPMALLPLPDQRMALVWTGPREQVDRWVALENSEVLAQLQ
EEEEEECCCCCCCHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHEECCCHHHHHHHH
ARCPAGAPRLSSIGERQRYPLVLTEACAQVVPYGVVVGNAAHTLHPVAGQGFNLAVRDLL
HHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCHHHCCCCCCCCCHHHHHHHH
ALAQTVGGNSDPGSLVTLQAYAQKREKDQAMISQASRWVPELFRLQHPLFAHSRQLGLVA
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHH
MDILPGLRSGFAKRAMGL
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGALLALLLRHHGAGRVVLVENHPLSLPESPPFTPSFDARSTALSAGTLSVLGDLGLAD
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCHHH
AIREHAAAIDTVHVSRQSRLGITRISAHEEGVDQLGAVVENRWLGFVLLGALFADKSIQV
HHHHHHHHHHHHHHCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
RAPETLSSICRVEGGYQVSLAGGEVLETPLLVAADGARSKTREWLGISAREHDTGHDALI
ECCHHHHHHHHCCCCEEEEECCCCHHHCCEEEEECCCCHHHHHHHCCCCCCCCCCCCEEE
ANVSLAAGHEGIAYERFLNDGPMALLPLPDQRMALVWTGPREQVDRWVALENSEVLAQLQ
EEEEEECCCCCCCHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHEECCCHHHHHHHH
ARCPAGAPRLSSIGERQRYPLVLTEACAQVVPYGVVVGNAAHTLHPVAGQGFNLAVRDLL
HHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCHHHCCCCCCCCCHHHHHHHH
ALAQTVGGNSDPGSLVTLQAYAQKREKDQAMISQASRWVPELFRLQHPLFAHSRQLGLVA
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHH
MDILPGLRSGFAKRAMGL
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]