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The map label for this gene is visC [H]

Identifier: 110835459

GI number: 110835459

Start: 2941729

End: 2943012

Strand: Reverse

Name: visC [H]

Synonym: ABO_2598

Alternate gene names: 110835459

Gene position: 2943012-2941729 (Counterclockwise)

Preceding gene: 110835460

Following gene: 110835458

Centisome position: 94.32

GC content: 60.75

Gene sequence:

>1284_bases
GTGCATCCCAATAGCGTGTCGTCTGCAAGCGAAAAACAACACATCGTCATCGTCGGCGGTGGCATGACTGGCGGGCTGCT
GGCGGTGCTGCTGGCGGAGCAGGGGCTTAATGTCACCGTGCTGGACGGTGCACCTGCTCCGGCCATGCCTGAGGGCGCAG
CACAATTACGGGTATCTACGCTTACCGAGGCCAGCCATTGGCTGTTGCGTAATACCGGGGTGTGGGATTGTCTAGATCTG
TCGCGGGTGCAGCCTTATCACGCCATGCAAGTGTGGGATCAGGATGGCACCGGTGAAGTGTTATTCCGGGCGGAAGAGAT
CGGGGCAAAGAGCCTGGGCTGGTTATTGGAAAACGGGCATTTGGCTGCTGCTCTGTATCGTAAAGCCGCAACCTTGCCGA
CGCTGGATTGGCAATGCGGTGTGCAGGTCGATGCCTTGCGGCGTGATGCCAAGACGGGGCAATGGGCCGTGCGCAGTGGC
GATTCGTTCTGGCAGGCTGACTTGCTAGTGGGCGCCGATGGCGCCCGTTCGCAAGTGCGAGAGCAGGCCGGCATCAGCGG
TGGGCCCCGCGATAGCGGGCACCATGCACTGGTGGCCACCATTGCCACGCAACGGCCCCATGACGGTTGTGCCAGGCAAG
TGTTTATGGAAACCGGGCCGTTGGCGTTGCTGCCGTTATTTACTGGCGAGGGTCAGGATGATCAAAGGCAGTGTTCTATT
GTTTGGTCCGGTTGGCCGCAGCGGATTGCGGCACTGCGAGACAAGGACGCAGCGGCGTTTGCGGCGGAATTGCAGGCTGC
TGTGGGCGGCGCTCTGGGGCCTGTGACCCTGCTTAGCGAACGAGCGGTGTTTCCCATTCAGGAGCGCCACGCTAGCCAGT
ATATATCTGCAGGGCTGGCGCTAGTGGGAGACGCAGCCCATGTGATCCATCCATTGGCTGGGCAGGGGGTGAACCTGGGA
TTGTTGGATGCGGCGGTACTGGCGGAAGAGGTGAAAAGGGCCTGTGAACAGGGATCCGGCTGTGCTGACCCTAGTGCGTT
GGCCCGTTATCAGCGCCGCCGTCGCGGAGAAAATTTGCTGATGCAAAATGCCATGCGTGGGTTCCAGTCCCTGTTTGAAC
AGCGCGCCCTGCCGGTGCGCTGGTTGCGTAACACGGGCATGCGCTGGGTAAATCAGGCGGGCCCAGTGAAAGGATTCTTT
GCTCGTCAGGCCATGGGGCGAAGCGCAGACCTTCCTGCTAAAGCGAGACCCCCCGTTTGGGACGCTAGAGCTAATCGACA
TTAG

Upstream 100 bases:

>100_bases
GCTGGGGCTAGTGGCCATGGATATTTTACCCGGGCTGCGCAGCGGTTTTGCGAAACGGGCCATGGGATTGTGAAAGCACT
TAAAAACGTGAGGACAAAGC

Downstream 100 bases:

>100_bases
CTGGCATACTGTCATTAATTAATAATCATTCCTGTTTGAGAATAGTTGGAGCGAATGGATATGCGCGTGTTTGGCATCAT
AGTTGGCGCCGTGATTATGG

Product: oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MHPNSVSSASEKQHIVIVGGGMTGGLLAVLLAEQGLNVTVLDGAPAPAMPEGAAQLRVSTLTEASHWLLRNTGVWDCLDL
SRVQPYHAMQVWDQDGTGEVLFRAEEIGAKSLGWLLENGHLAAALYRKAATLPTLDWQCGVQVDALRRDAKTGQWAVRSG
DSFWQADLLVGADGARSQVREQAGISGGPRDSGHHALVATIATQRPHDGCARQVFMETGPLALLPLFTGEGQDDQRQCSI
VWSGWPQRIAALRDKDAAAFAAELQAAVGGALGPVTLLSERAVFPIQERHASQYISAGLALVGDAAHVIHPLAGQGVNLG
LLDAAVLAEEVKRACEQGSGCADPSALARYQRRRRGENLLMQNAMRGFQSLFEQRALPVRWLRNTGMRWVNQAGPVKGFF
ARQAMGRSADLPAKARPPVWDARANRH

Sequences:

>Translated_427_residues
MHPNSVSSASEKQHIVIVGGGMTGGLLAVLLAEQGLNVTVLDGAPAPAMPEGAAQLRVSTLTEASHWLLRNTGVWDCLDL
SRVQPYHAMQVWDQDGTGEVLFRAEEIGAKSLGWLLENGHLAAALYRKAATLPTLDWQCGVQVDALRRDAKTGQWAVRSG
DSFWQADLLVGADGARSQVREQAGISGGPRDSGHHALVATIATQRPHDGCARQVFMETGPLALLPLFTGEGQDDQRQCSI
VWSGWPQRIAALRDKDAAAFAAELQAAVGGALGPVTLLSERAVFPIQERHASQYISAGLALVGDAAHVIHPLAGQGVNLG
LLDAAVLAEEVKRACEQGSGCADPSALARYQRRRRGENLLMQNAMRGFQSLFEQRALPVRWLRNTGMRWVNQAGPVKGFF
ARQAMGRSADLPAKARPPVWDARANRH
>Mature_427_residues
MHPNSVSSASEKQHIVIVGGGMTGGLLAVLLAEQGLNVTVLDGAPAPAMPEGAAQLRVSTLTEASHWLLRNTGVWDCLDL
SRVQPYHAMQVWDQDGTGEVLFRAEEIGAKSLGWLLENGHLAAALYRKAATLPTLDWQCGVQVDALRRDAKTGQWAVRSG
DSFWQADLLVGADGARSQVREQAGISGGPRDSGHHALVATIATQRPHDGCARQVFMETGPLALLPLFTGEGQDDQRQCSI
VWSGWPQRIAALRDKDAAAFAAELQAAVGGALGPVTLLSERAVFPIQERHASQYISAGLALVGDAAHVIHPLAGQGVNLG
LLDAAVLAEEVKRACEQGSGCADPSALARYQRRRRGENLLMQNAMRGFQSLFEQRALPVRWLRNTGMRWVNQAGPVKGFF
ARQAMGRSADLPAKARPPVWDARANRH

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=391, Percent_Identity=29.4117647058824, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI32967307, Length=357, Percent_Identity=28.8515406162465, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1789273, Length=399, Percent_Identity=40.1002506265664, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1786883, Length=398, Percent_Identity=36.9346733668342, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=28.8607594936709, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25146631, Length=441, Percent_Identity=27.6643990929705, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321694, Length=464, Percent_Identity=24.5689655172414, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920760, Length=445, Percent_Identity=29.8876404494382, Blast_Score=165, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45887; Mature: 45887

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPNSVSSASEKQHIVIVGGGMTGGLLAVLLAEQGLNVTVLDGAPAPAMPEGAAQLRVST
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHEEHHH
LTEASHWLLRNTGVWDCLDLSRVQPYHAMQVWDQDGTGEVLFRAEEIGAKSLGWLLENGH
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHEEECCCCCCCEEEEHHHHCCHHHHHHHCCCC
LAAALYRKAATLPTLDWQCGVQVDALRRDAKTGQWAVRSGDSFWQADLLVGADGARSQVR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCHHHHHH
EQAGISGGPRDSGHHALVATIATQRPHDGCARQVFMETGPLALLPLFTGEGQDDQRQCSI
HHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEE
VWSGWPQRIAALRDKDAAAFAAELQAAVGGALGPVTLLSERAVFPIQERHASQYISAGLA
EECCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVGDAAHVIHPLAGQGVNLGLLDAAVLAEEVKRACEQGSGCADPSALARYQRRRRGENLL
HHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHH
MQNAMRGFQSLFEQRALPVRWLRNTGMRWVNQAGPVKGFFARQAMGRSADLPAKARPPVW
HHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
DARANRH
CCCCCCC
>Mature Secondary Structure
MHPNSVSSASEKQHIVIVGGGMTGGLLAVLLAEQGLNVTVLDGAPAPAMPEGAAQLRVST
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHEEHHH
LTEASHWLLRNTGVWDCLDLSRVQPYHAMQVWDQDGTGEVLFRAEEIGAKSLGWLLENGH
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHEEECCCCCCCEEEEHHHHCCHHHHHHHCCCC
LAAALYRKAATLPTLDWQCGVQVDALRRDAKTGQWAVRSGDSFWQADLLVGADGARSQVR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCHHHHHH
EQAGISGGPRDSGHHALVATIATQRPHDGCARQVFMETGPLALLPLFTGEGQDDQRQCSI
HHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEE
VWSGWPQRIAALRDKDAAAFAAELQAAVGGALGPVTLLSERAVFPIQERHASQYISAGLA
EECCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVGDAAHVIHPLAGQGVNLGLLDAAVLAEEVKRACEQGSGCADPSALARYQRRRRGENLL
HHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHH
MQNAMRGFQSLFEQRALPVRWLRNTGMRWVNQAGPVKGFFARQAMGRSADLPAKARPPVW
HHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
DARANRH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]