Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 110835405

GI number: 110835405

Start: 2885130

End: 2885459

Strand: Reverse

Name: sugE [H]

Synonym: ABO_2544

Alternate gene names: 110835405

Gene position: 2885459-2885130 (Counterclockwise)

Preceding gene: 110835406

Following gene: 110835404

Centisome position: 92.48

GC content: 53.94

Gene sequence:

>330_bases
ATGAATCTGTATTGGGTCGTGTTATTACTGGCGGTGATTGTGGAAATCGCTTGGGCCATGAGTCTCAAATGGATCCAGCT
TAGCCCAGGGGTGCTCTCTATTGGTACTTCACTTGTGCTCACCGGCTTGAATATGTTGATGTTGTCCTATGCGATGCGGG
GCATTCCCGTGGGCACGGCATACGCCATCTGGACAGGGCTCGGTGCGGTGGGTATTACCCTGATCGGTATCGTGTTCTTC
AAGGATCCGGCCAATGCGTCACGGCTGGCCTTTATGGCATTGATTGTGGTGGGGATTGTCGGCCTGAAGTTGACCAGTGG
TCCGGCCTGA

Upstream 100 bases:

>100_bases
GGCTGTCTCTTTCCGGGTTTCCGGCAGTGCTGTTTTCCTGACGAGCCCGTGTCCGCCGTGTGCCAATGTGGTGGGCGGGC
TTGTGTTGGAGAAAGTGGGG

Downstream 100 bases:

>100_bases
AAGAGGCGAGGGTGAGGTAAGGGTTGGATCTGATGGCTGATGTGGTGCCGAATCGTTCGTTCGGGTATTTTACAATCTTT
TCCCGCTAACGCGTTGATAC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MNLYWVVLLLAVIVEIAWAMSLKWIQLSPGVLSIGTSLVLTGLNMLMLSYAMRGIPVGTAYAIWTGLGAVGITLIGIVFF
KDPANASRLAFMALIVVGIVGLKLTSGPA

Sequences:

>Translated_109_residues
MNLYWVVLLLAVIVEIAWAMSLKWIQLSPGVLSIGTSLVLTGLNMLMLSYAMRGIPVGTAYAIWTGLGAVGITLIGIVFF
KDPANASRLAFMALIVVGIVGLKLTSGPA
>Mature_109_residues
MNLYWVVLLLAVIVEIAWAMSLKWIQLSPGVLSIGTSLVLTGLNMLMLSYAMRGIPVGTAYAIWTGLGAVGITLIGIVFF
KDPANASRLAFMALIVVGIVGLKLTSGPA

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=108, Percent_Identity=44.4444444444444, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1787884, Length=103, Percent_Identity=35.9223300970874, Blast_Score=65, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11506; Mature: 11506

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYWVVLLLAVIVEIAWAMSLKWIQLSPGVLSIGTSLVLTGLNMLMLSYAMRGIPVGTA
CCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YAIWTGLGAVGITLIGIVFFKDPANASRLAFMALIVVGIVGLKLTSGPA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNLYWVVLLLAVIVEIAWAMSLKWIQLSPGVLSIGTSLVLTGLNMLMLSYAMRGIPVGTA
CCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YAIWTGLGAVGITLIGIVFFKDPANASRLAFMALIVVGIVGLKLTSGPA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]