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The map label for this gene is phoP [H]

Identifier: 110835404

GI number: 110835404

Start: 2884289

End: 2885008

Strand: Reverse

Name: phoP [H]

Synonym: ABO_2543

Alternate gene names: 110835404

Gene position: 2885008-2884289 (Counterclockwise)

Preceding gene: 110835405

Following gene: 110835403

Centisome position: 92.46

GC content: 53.06

Gene sequence:

>720_bases
ATGTTGGCCTGCAACAGATGGAGTTTAACCGTGCGCATTGCTTATCTCGAAGATGACATGGCCCAGGCGGAGCTGGTCAC
TCACTGGCTTAAAGAGGCTGGCCATAACTGTATTCACATGGCCAGTGGCCGTGATTTTATGTCCCTTCTGCGTCGTGACA
CCTTCGATATTTTGGTGCTCGACTGGGAAGTGCCAGACATGAACGGCTACGCTGTGCTCGAAGAAGTACGAGCCAGCGGT
AATCGCACCCCTGTGTTATTCGCGACGCAGCGTGATGATGAATCATCCATTGTCGGCGCACTTTCTCAAGGGGCGGATGA
TTATATGGTGAAGCCTACCAAGCAAGCGGAATTGCTGGCCCGTATTAGCGCTCTCGGGCGTCGGGCAGGGGTATCGGAAA
TGGATGAAGAAACCACGCTGAATGTGGGGCCGTGGACCGTGGACCGGTCCCGGCGTCAGATCCTGCTGGATGAAGAAGCG
ATTAAATTGACTGACAAGGATTACGAGCTGGCCTGCTATTTGTTCCAAAATGTGGGCAAACTCATGAGTCGGGCGCACTT
GCTGGAGAAGGTTTGGGGTATCATGACCCCGATTGAATCACGCACCGTTGACGTGCATATCAGCCGGATTCGACGTAGCC
TGCAAATTCGCCCTGAACGAGGCTATCGAATTAAAACGGTGTACCAGCACGGATATCGTCTGGAGCCGATCGAAGAATAA

Upstream 100 bases:

>100_bases
GGTTGGATCTGATGGCTGATGTGGTGCCGAATCGTTCGTTCGGGTATTTTACAATCTTTTCCCGCTAACGCGTTGATACA
TCGGTACCCTTTGCGGGCAG

Downstream 100 bases:

>100_bases
GGACACATCTATGAGGGTCTGGTTGAGCACGGCCATGCTGCTGTGCCTGCTATCAACGGCCTGGGCCGGGGATGATTGGC
ATTATACCTTGCGCCCTGGC

Product: DNA-binding heavy metal response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLACNRWSLTVRIAYLEDDMAQAELVTHWLKEAGHNCIHMASGRDFMSLLRRDTFDILVLDWEVPDMNGYAVLEEVRASG
NRTPVLFATQRDDESSIVGALSQGADDYMVKPTKQAELLARISALGRRAGVSEMDEETTLNVGPWTVDRSRRQILLDEEA
IKLTDKDYELACYLFQNVGKLMSRAHLLEKVWGIMTPIESRTVDVHISRIRRSLQIRPERGYRIKTVYQHGYRLEPIEE

Sequences:

>Translated_239_residues
MLACNRWSLTVRIAYLEDDMAQAELVTHWLKEAGHNCIHMASGRDFMSLLRRDTFDILVLDWEVPDMNGYAVLEEVRASG
NRTPVLFATQRDDESSIVGALSQGADDYMVKPTKQAELLARISALGRRAGVSEMDEETTLNVGPWTVDRSRRQILLDEEA
IKLTDKDYELACYLFQNVGKLMSRAHLLEKVWGIMTPIESRTVDVHISRIRRSLQIRPERGYRIKTVYQHGYRLEPIEE
>Mature_239_residues
MLACNRWSLTVRIAYLEDDMAQAELVTHWLKEAGHNCIHMASGRDFMSLLRRDTFDILVLDWEVPDMNGYAVLEEVRASG
NRTPVLFATQRDDESSIVGALSQGADDYMVKPTKQAELLARISALGRRAGVSEMDEETTLNVGPWTVDRSRRQILLDEEA
IKLTDKDYELACYLFQNVGKLMSRAHLLEKVWGIMTPIESRTVDVHISRIRRSLQIRPERGYRIKTVYQHGYRLEPIEE

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=31.0043668122271, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=31.858407079646, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=29.2576419213974, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.0357142857143, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=30.3964757709251, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.4372294372294, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=29.0748898678414, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.4410480349345, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=35.4285714285714, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=27.8260869565217, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=28.6363636363636, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=29.3617021276596, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=30.622009569378, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=33.0097087378641, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=103, Percent_Identity=31.0679611650485, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=30.9090909090909, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27469; Mature: 27469

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLACNRWSLTVRIAYLEDDMAQAELVTHWLKEAGHNCIHMASGRDFMSLLRRDTFDILVL
CCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEE
DWEVPDMNGYAVLEEVRASGNRTPVLFATQRDDESSIVGALSQGADDYMVKPTKQAELLA
EEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEECCCHHHHHHH
RISALGRRAGVSEMDEETTLNVGPWTVDRSRRQILLDEEAIKLTDKDYELACYLFQNVGK
HHHHHHHHCCCCCCCCCCEEECCCEEECCCCCEEEECCCCEEECCCCHHHHHHHHHHHHH
LMSRAHLLEKVWGIMTPIESRTVDVHISRIRRSLQIRPERGYRIKTVYQHGYRLEPIEE
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLACNRWSLTVRIAYLEDDMAQAELVTHWLKEAGHNCIHMASGRDFMSLLRRDTFDILVL
CCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEE
DWEVPDMNGYAVLEEVRASGNRTPVLFATQRDDESSIVGALSQGADDYMVKPTKQAELLA
EEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEECCCHHHHHHH
RISALGRRAGVSEMDEETTLNVGPWTVDRSRRQILLDEEAIKLTDKDYELACYLFQNVGK
HHHHHHHHCCCCCCCCCCEEECCCEEECCCCCEEEECCCCEEECCCCHHHHHHHHHHHHH
LMSRAHLLEKVWGIMTPIESRTVDVHISRIRRSLQIRPERGYRIKTVYQHGYRLEPIEE
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA