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The map label for this gene is moaB-1 [H]

Identifier: 110835244

GI number: 110835244

Start: 2707276

End: 2707788

Strand: Reverse

Name: moaB-1 [H]

Synonym: ABO_2383

Alternate gene names: 110835244

Gene position: 2707788-2707276 (Counterclockwise)

Preceding gene: 110835246

Following gene: 110835243

Centisome position: 86.78

GC content: 58.09

Gene sequence:

>513_bases
ATGTCCAAACCTGCGGCTAGATTTGAGCCCTTGGCGCTGGCGGTATTGACCGTGAGTGATACCCGAACCCCGGAAACCGA
TACCTCCGGAGACCTGCTGGTAGCGCGGTTAAAAGAGGCGGGGCATACCCTGCAAGCGCGGCAGATAGTGAAGGACGATA
TCTATCAGCTGCGCAAGGTGGTTTCTGATTGGATTGCCGACGATCGGATACAAGGGATTGTGACTACCGGTGGCACCGGG
TTTTCAGGGCGGGACTCCACCCCGGAGGCGCTGGCGCCTCTGTTCGACAAGACCATTGAGGGGTTTGGCGAACTGTTCCG
GCAGGTGAGCGTGGAGGATATCGGTTCTTCCACTATTCAGAGTCGTTGCCTGGCCGGGCTGGCCAACCGCACGGTGATTT
TTTGCCTGCCAGGGTCCAATAATGCGTGTGCCACAGGGTGGGACCGCATTATTGTCGAGCAGCTGGATGCCCGTCATCGG
CCCTGTAACTTTGTTGCCCAAGTGCGCCGATAA

Upstream 100 bases:

>100_bases
TAGAACAGGGGCTGTTGGCAACGGTCAAATCATGCTGTGCTGTCCAGCCGCCCAGGTATGACACGTGCTAGCATTGGCGG
ATTGCGTAAGGAGAGAATGT

Downstream 100 bases:

>100_bases
AGCGAATGTTGTCGCGGTGATTTGAAAGGAAGAGAAAAATGCACGCAGGCAAGCAACCCTTAATGCCAGTGGCACAAGCG
CTGGAGCGGTTACTGGATTC

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSKPAARFEPLALAVLTVSDTRTPETDTSGDLLVARLKEAGHTLQARQIVKDDIYQLRKVVSDWIADDRIQGIVTTGGTG
FSGRDSTPEALAPLFDKTIEGFGELFRQVSVEDIGSSTIQSRCLAGLANRTVIFCLPGSNNACATGWDRIIVEQLDARHR
PCNFVAQVRR

Sequences:

>Translated_170_residues
MSKPAARFEPLALAVLTVSDTRTPETDTSGDLLVARLKEAGHTLQARQIVKDDIYQLRKVVSDWIADDRIQGIVTTGGTG
FSGRDSTPEALAPLFDKTIEGFGELFRQVSVEDIGSSTIQSRCLAGLANRTVIFCLPGSNNACATGWDRIIVEQLDARHR
PCNFVAQVRR
>Mature_169_residues
SKPAARFEPLALAVLTVSDTRTPETDTSGDLLVARLKEAGHTLQARQIVKDDIYQLRKVVSDWIADDRIQGIVTTGGTGF
SGRDSTPEALAPLFDKTIEGFGELFRQVSVEDIGSSTIQSRCLAGLANRTVIFCLPGSNNACATGWDRIIVEQLDARHRP
CNFVAQVRR

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=137, Percent_Identity=34.3065693430657, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI10880983, Length=137, Percent_Identity=34.3065693430657, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787000, Length=170, Percent_Identity=51.7647058823529, Blast_Score=187, Evalue=4e-49,
Organism=Drosophila melanogaster, GI17136978, Length=168, Percent_Identity=34.5238095238095, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24638841, Length=168, Percent_Identity=34.5238095238095, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18559; Mature: 18428

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPAARFEPLALAVLTVSDTRTPETDTSGDLLVARLKEAGHTLQARQIVKDDIYQLRKV
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSDWIADDRIQGIVTTGGTGFSGRDSTPEALAPLFDKTIEGFGELFRQVSVEDIGSSTIQ
HHHHHCCCHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SRCLAGLANRTVIFCLPGSNNACATGWDRIIVEQLDARHRPCNFVAQVRR
HHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
SKPAARFEPLALAVLTVSDTRTPETDTSGDLLVARLKEAGHTLQARQIVKDDIYQLRKV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSDWIADDRIQGIVTTGGTGFSGRDSTPEALAPLFDKTIEGFGELFRQVSVEDIGSSTIQ
HHHHHCCCHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SRCLAGLANRTVIFCLPGSNNACATGWDRIIVEQLDARHRPCNFVAQVRR
HHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]