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The map label for this gene is xerC

Identifier: 110835195

GI number: 110835195

Start: 2661121

End: 2662044

Strand: Direct

Name: xerC

Synonym: ABO_2334

Alternate gene names: 110835195

Gene position: 2661121-2662044 (Clockwise)

Preceding gene: 110835194

Following gene: 110835196

Centisome position: 85.29

GC content: 57.79

Gene sequence:

>924_bases
GTGGATAGCGATAGCCATAACACACTGCAAACGGTTAACACCTTCCTAACCCACTTGGCCAGCGAGCGTCGCCTCTCACC
GCACACCGTAAACGGCTATCAACGGGACCTGATCGAAGCCCGAACATTACTCGGCAGCCAACCCTGGGACACCCTCACCG
TCCACGACATGCGCAGCCTCGCCGCCTCGCTACACCGCCAAGGGAAAAGCGGCAAAACTATTCAGCGCATGCTTTCCACC
CTGCGTACGTTTTTCCGTTACCTGATGCGTGAAGGGCTTGCCCGCGACAACCCGGCCATAGACATTCGCGCCCCGAAAAG
CGGTAAACGCCTGCCCAAAGCACTGGATGTAGATCAAGTCAGCCATTTGCTGGATGCCGGCACCAGCAACAGCGAACCCC
TAGCCCTGCGCGATCAAGCCATAATGGAACTGCTCTATGCCTGCGGCCTGCGTTTGGCCGAACTGCTTAGCCTAAACCTA
GACAGCATTGATCTGCATGAAAGCCAACTGTTGGTCACCGGTAAAGGCAACAAGACCCGGCAACTACCAGTGGGAAAACC
CGCCCTCACCGCCGTGCGCCGCTGGTTGCAAGTGCGTCCCATGCTGATCAAAAGCAGCGACCAGAACGCTCTTTTTATCA
GCAAAAACGGCCGGCGGCTGTCTCCTTCCAGCGTACAACAGCGGCTTAAACGCCATGCTCTGGAGCGGGGGCTCGATGCC
CATCTACATCCGCACAAATTACGCCACTCCTTCGCCACACACCTGCTGGAATCCTCCGGCGACTTGCGGGCAGTGCAGGA
ACTGCTCGGCCACGCAGACTTGGCCACCACCCAGGTTTACACTCACCTGGATTTCCAACACTTAGCTCAGGTCTACGACG
GAGCACACCCAAGAGCCCAGCGCCGCAAGGACGATGACGAATAA

Upstream 100 bases:

>100_bases
GGCCAGGTACTCAGCCGCAGACTCCACGAAGTGGTGCGCCAATACCCCCACCAAGCAGCCAAAAAAACCAGCGACATTAG
CTGATAAAGGACCGTTAACC

Downstream 100 bases:

>100_bases
GCCTTGGCGCCTAACGCTGGGCACACAATGCTTGGCGCCAGTGAACCTGTATGCTGCCATTAAGCGTTTTACGGTAAACT
ACCCACCATGAGCATGCTCA

Product: integrase/recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDSDSHNTLQTVNTFLTHLASERRLSPHTVNGYQRDLIEARTLLGSQPWDTLTVHDMRSLAASLHRQGKSGKTIQRMLST
LRTFFRYLMREGLARDNPAIDIRAPKSGKRLPKALDVDQVSHLLDAGTSNSEPLALRDQAIMELLYACGLRLAELLSLNL
DSIDLHESQLLVTGKGNKTRQLPVGKPALTAVRRWLQVRPMLIKSSDQNALFISKNGRRLSPSSVQQRLKRHALERGLDA
HLHPHKLRHSFATHLLESSGDLRAVQELLGHADLATTQVYTHLDFQHLAQVYDGAHPRAQRRKDDDE

Sequences:

>Translated_307_residues
MDSDSHNTLQTVNTFLTHLASERRLSPHTVNGYQRDLIEARTLLGSQPWDTLTVHDMRSLAASLHRQGKSGKTIQRMLST
LRTFFRYLMREGLARDNPAIDIRAPKSGKRLPKALDVDQVSHLLDAGTSNSEPLALRDQAIMELLYACGLRLAELLSLNL
DSIDLHESQLLVTGKGNKTRQLPVGKPALTAVRRWLQVRPMLIKSSDQNALFISKNGRRLSPSSVQQRLKRHALERGLDA
HLHPHKLRHSFATHLLESSGDLRAVQELLGHADLATTQVYTHLDFQHLAQVYDGAHPRAQRRKDDDE
>Mature_307_residues
MDSDSHNTLQTVNTFLTHLASERRLSPHTVNGYQRDLIEARTLLGSQPWDTLTVHDMRSLAASLHRQGKSGKTIQRMLST
LRTFFRYLMREGLARDNPAIDIRAPKSGKRLPKALDVDQVSHLLDAGTSNSEPLALRDQAIMELLYACGLRLAELLSLNL
DSIDLHESQLLVTGKGNKTRQLPVGKPALTAVRRWLQVRPMLIKSSDQNALFISKNGRRLSPSSVQQRLKRHALERGLDA
HLHPHKLRHSFATHLLESSGDLRAVQELLGHADLATTQVYTHLDFQHLAQVYDGAHPRAQRRKDDDE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=47.7966101694915, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=39.3220338983051, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790768, Length=158, Percent_Identity=31.0126582278481, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790767, Length=183, Percent_Identity=27.3224043715847, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_ALCBS (Q0VM16)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694054.1
- ProteinModelPortal:   Q0VM16
- SMR:   Q0VM16
- STRING:   Q0VM16
- GeneID:   4211777
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2334
- NMPDR:   fig|393595.12.peg.2335
- eggNOG:   COG4973
- HOGENOM:   HBG727654
- OMA:   HAQGLGP
- PhylomeDB:   Q0VM16
- ProtClustDB:   CLSK726371
- BioCyc:   ABOR393595:ABO_2334-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34598; Mature: 34598

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: ACT_SITE 151-151 ACT_SITE 175-175 ACT_SITE 245-245 ACT_SITE 248-248 ACT_SITE 271-271 ACT_SITE 280-280

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDSHNTLQTVNTFLTHLASERRLSPHTVNGYQRDLIEARTLLGSQPWDTLTVHDMRSL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AASLHRQGKSGKTIQRMLSTLRTFFRYLMREGLARDNPAIDIRAPKSGKRLPKALDVDQV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHH
SHLLDAGTSNSEPLALRDQAIMELLYACGLRLAELLSLNLDSIDLHESQLLVTGKGNKTR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCC
QLPVGKPALTAVRRWLQVRPMLIKSSDQNALFISKNGRRLSPSSVQQRLKRHALERGLDA
CCCCCCHHHHHHHHHHHHCHHHEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
HLHPHKLRHSFATHLLESSGDLRAVQELLGHADLATTQVYTHLDFQHLAQVYDGAHPRAQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHH
RRKDDDE
CCCCCCC
>Mature Secondary Structure
MDSDSHNTLQTVNTFLTHLASERRLSPHTVNGYQRDLIEARTLLGSQPWDTLTVHDMRSL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AASLHRQGKSGKTIQRMLSTLRTFFRYLMREGLARDNPAIDIRAPKSGKRLPKALDVDQV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHH
SHLLDAGTSNSEPLALRDQAIMELLYACGLRLAELLSLNLDSIDLHESQLLVTGKGNKTR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCC
QLPVGKPALTAVRRWLQVRPMLIKSSDQNALFISKNGRRLSPSSVQQRLKRHALERGLDA
CCCCCCHHHHHHHHHHHHCHHHEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
HLHPHKLRHSFATHLLESSGDLRAVQELLGHADLATTQVYTHLDFQHLAQVYDGAHPRAQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHH
RRKDDDE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA