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The map label for this gene is hemX [H]

Identifier: 110835181

GI number: 110835181

Start: 2647682

End: 2648647

Strand: Reverse

Name: hemX [H]

Synonym: ABO_2320

Alternate gene names: 110835181

Gene position: 2648647-2647682 (Counterclockwise)

Preceding gene: 110835182

Following gene: 110835180

Centisome position: 84.89

GC content: 59.42

Gene sequence:

>966_bases
ATGACGCAGGATCGTCCTTTTTTCCGCCAAACCGGGGTAAGCCTTCTGGCTGTGCTGCTTGTATTGGTGGTGCTGGTTGC
ACTTGGCGCTGCTGGCTGGTGGGGGTGGCAGGAGTTTACCCGGCTGAAGAACGAAAAGAGCGGCCTTGCTGATCAGGTGG
CGACAGTGAAAAGTGAGCTGACCAGTCAGCATCGCCAAGTACAGGCCGCATTATCTGACTTAGAAAAACGGCAGGCCAAG
CTAGCTGCGCAGATGACCAACGACCGCGCAGCCTTGACCGATATAAAAAGCGGTGGGCAGCGACTGTGGTTGATCAATGA
GGCCCGGGCACTGGCGAGTCTGGCCAGCCAGAGACTGTTGCTTACCCAAGATACGTTGGCAGCACGCCGTTTGTTAAAGG
CCGCAGATGAGGTCTTGGCTCGCCTAGGTGATCCAGCCGTGTTGCCGGCCCGCAAAGCACTGGCCATGGATATGGAAATT
CTCAGTGGCGCCAGCCAGGTGGATGTGCAGGGCATGGTGTTGCGTTTGGGCGCGTTGCGAGAGCTGGTAGTCGAACTGGC
TGTACCGGCAGAAGCATTGCCATCGGAACGTGACCAGCCGGGAGTGGATCAGGGTTGGTGGCAGAGTGTGATCGACCGGA
TGCCGATAACCGTGCGCCGCCATGACAGTGCGGTACCTCTGCCATTGTCGGGGGAGCAGGCCGCACTGGTGCGTCTGACT
TTGGATGGCAGCCTGCAGCAGGCGCAGCTTGCACTGATGCAGGGGCGTGCTGACGCCTACCGTCAGGCGGTTGAAAGTGC
CGAGTCGACACTCAAGCAATGGTTCCGTGGTGACGATCCCCGTGCCGCACAAATGCAGACCACCCTGAAGGAAATGAGCG
GCGCCCAAGTGGCCCAAGCGTTGCCGCAGATCGGTAATGGCTTGGCGGCAATTGAAGCTCTCAAGCGCAAGGAGGGCGAG
GCATGA

Upstream 100 bases:

>100_bases
CAATGGGCGGTCACTTTAAGGTTTTTGCAATGAGATCGGGTATCGCCGCTGCGCAATTGAGTGTTGCGCTGGCCTCGCTT
ACGACAACAACGGAGCTGAT

Downstream 100 bases:

>100_bases
AGAAACTCGTCCTGCTGATTATTATTGCGTTGGTCGCCGCGTTGGCGCTGGGGCGTTGGATGGCAGCGGATTCCGGTTAT
GTGCTGATTATCCGCGACAC

Product: uroporphyrin-III C-methyltransferase

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTQDRPFFRQTGVSLLAVLLVLVVLVALGAAGWWGWQEFTRLKNEKSGLADQVATVKSELTSQHRQVQAALSDLEKRQAK
LAAQMTNDRAALTDIKSGGQRLWLINEARALASLASQRLLLTQDTLAARRLLKAADEVLARLGDPAVLPARKALAMDMEI
LSGASQVDVQGMVLRLGALRELVVELAVPAEALPSERDQPGVDQGWWQSVIDRMPITVRRHDSAVPLPLSGEQAALVRLT
LDGSLQQAQLALMQGRADAYRQAVESAESTLKQWFRGDDPRAAQMQTTLKEMSGAQVAQALPQIGNGLAAIEALKRKEGE
A

Sequences:

>Translated_321_residues
MTQDRPFFRQTGVSLLAVLLVLVVLVALGAAGWWGWQEFTRLKNEKSGLADQVATVKSELTSQHRQVQAALSDLEKRQAK
LAAQMTNDRAALTDIKSGGQRLWLINEARALASLASQRLLLTQDTLAARRLLKAADEVLARLGDPAVLPARKALAMDMEI
LSGASQVDVQGMVLRLGALRELVVELAVPAEALPSERDQPGVDQGWWQSVIDRMPITVRRHDSAVPLPLSGEQAALVRLT
LDGSLQQAQLALMQGRADAYRQAVESAESTLKQWFRGDDPRAAQMQTTLKEMSGAQVAQALPQIGNGLAAIEALKRKEGE
A
>Mature_320_residues
TQDRPFFRQTGVSLLAVLLVLVVLVALGAAGWWGWQEFTRLKNEKSGLADQVATVKSELTSQHRQVQAALSDLEKRQAKL
AAQMTNDRAALTDIKSGGQRLWLINEARALASLASQRLLLTQDTLAARRLLKAADEVLARLGDPAVLPARKALAMDMEIL
SGASQVDVQGMVLRLGALRELVVELAVPAEALPSERDQPGVDQGWWQSVIDRMPITVRRHDSAVPLPLSGEQAALVRLTL
DGSLQQAQLALMQGRADAYRQAVESAESTLKQWFRGDDPRAAQMQTTLKEMSGAQVAQALPQIGNGLAAIEALKRKEGEA

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=301, Percent_Identity=27.5747508305648, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 34875; Mature: 34743

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDRPFFRQTGVSLLAVLLVLVVLVALGAAGWWGWQEFTRLKNEKSGLADQVATVKSEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TSQHRQVQAALSDLEKRQAKLAAQMTNDRAALTDIKSGGQRLWLINEARALASLASQRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
LTQDTLAARRLLKAADEVLARLGDPAVLPARKALAMDMEILSGASQVDVQGMVLRLGALR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ELVVELAVPAEALPSERDQPGVDQGWWQSVIDRMPITVRRHDSAVPLPLSGEQAALVRLT
HHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEEE
LDGSLQQAQLALMQGRADAYRQAVESAESTLKQWFRGDDPRAAQMQTTLKEMSGAQVAQA
ECCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LPQIGNGLAAIEALKRKEGEA
HHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQDRPFFRQTGVSLLAVLLVLVVLVALGAAGWWGWQEFTRLKNEKSGLADQVATVKSEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TSQHRQVQAALSDLEKRQAKLAAQMTNDRAALTDIKSGGQRLWLINEARALASLASQRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
LTQDTLAARRLLKAADEVLARLGDPAVLPARKALAMDMEILSGASQVDVQGMVLRLGALR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ELVVELAVPAEALPSERDQPGVDQGWWQSVIDRMPITVRRHDSAVPLPLSGEQAALVRLT
HHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEEE
LDGSLQQAQLALMQGRADAYRQAVESAESTLKQWFRGDDPRAAQMQTTLKEMSGAQVAQA
ECCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LPQIGNGLAAIEALKRKEGEA
HHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]