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The map label for this gene is p450 [H]

Identifier: 110835149

GI number: 110835149

Start: 2608295

End: 2609707

Strand: Direct

Name: p450 [H]

Synonym: ABO_2288

Alternate gene names: 110835149

Gene position: 2608295-2609707 (Clockwise)

Preceding gene: 110835147

Following gene: 110835150

Centisome position: 83.6

GC content: 50.39

Gene sequence:

>1413_bases
ATGTCAACGAGTTCAAGTACAAGTAATGACATCCAGGCAAAAATAATTAACGCCACATCCAAAGTCGTGCCAATGCATCT
ACAGATCAAGGCACTAAAAAACTTGATGAAGGTGAAGCGGAAGACCATTGGCACTTCCCGCCCTCAGGTGCACTTTGTTG
AAACCGATTTGCCTGACGTCAATGATTTGGCGATAGAAGATATCGATACGAGTAACCCTTTTTTATACCGACAAGGTAAG
GCGAATGCGTACTTTAAGCGGTTGCGTGATGAAGCGCCGGTGCACTACCAGAAGAACAGTGCTTTCGGGCCGTTCTGGTC
GGTAACACGCTACGAAGATATTGTCTTCGTGGACAAGAGCCATGATTTGTTTTCCGCCGAACCCCAAATTATCTTGGGTG
ATCCTCCGGAAGGCCTGTCGGTTGAAATGTTCATCGCTATGGATCCTCCCAAGCACGACGTACAGCGTCGGGCAGTCCAG
GGTGTTGTTGCGCCCAAGAACCTGAAAGAAATGGAAGGACTGATCCGCAAGCGCACCGGGGACGTACTCGATAGCCTGCC
GTTGGACACTCCGTTCAACTGGGTGCCGGTGGTGTCGAAAGAGCTGACCGGGCGCATGCTCGCCTCACTGTTAGATTTCC
CGTATGACGAACGCGAAAAACTGGTTGGCTGGTCGGATCGATTGTCCGGCGCGTCCTCGGCAACCGGCGGCGAGTTTACG
AATGAAGATGTGTTTTTTGATGATGCTGCAGATATGGCGTGGGCTTTCTCCAAGCTTTGGCGTGATAAAGAAGCCCGTCA
AAAAGCAGGTGAAGAGCCGGGTTTCGATTTGATCAGCATGCTTCAGTCCAATGAAGACACAAAAGATCTGATCAATCGTC
CTTTGGAATTCATTGGTAATCTCGCGTTGTTGATTGTTGGCGGTAATGACACCACGCGTAACTCAATGAGCGGGGGGGTG
CTGGCTTTAAATCAGTTCCCAGAGCAATTCGAGAAGCTAAAGGCGAACCCAAAGCTTATCCCCAATATGGTCTCTGAAAT
CATTCGCTGGCAAACGCCGCTTGCGTATATGCGCCGGGTTGCCAAGCAGGATGTGGAGCTGAACGGACAGACCATCAAGA
AGGGTGATCGCGTGCTGATGTGGTATGCGTCGGGCAACCAGGATGAGAGAAAATTTGAGAATCCTGAGCAATTCATCATC
GACCGCAAAGATACGCGTAACCATGTGTCGTTTGGTTATGGGGTTCACCGTTGTATGGGCAACCGCCTTGCCGAACTGCA
GCTGCGTATTCTGTGGGAAGAGCTTCTCCCTCGCTTTGAAAACATCGAAGTGATCGGTGAGCCGGAGCGCGTGCAATCGA
ACTTTGTGCGGGGCTATTCCAAGATGATGGTTAAGTTGACGGCTAAAAAATAA

Upstream 100 bases:

>100_bases
CAAAAACCTCTCGGTTGGGGTGTCAGGTTAAGGCCACGGAGACAATGGACGGAATGACTGTTCAATTGCCAGAATTTCAA
ATGTAAGTGCGGAGAGCGAC

Downstream 100 bases:

>100_bases
TGACTCGCCAGAACGGAAAGGTGGCCGAACAACAATCCGACAAAGCAATATTACTGTCGGTCTTGGGTCAAAGGCATACA
GTGTTCGGTACGGAAGAATT

Product: cytochrome P450

Products: NA

Alternate protein names: Cytochrome P450 111; Cytochrome P450lin [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSTSSSTSNDIQAKIINATSKVVPMHLQIKALKNLMKVKRKTIGTSRPQVHFVETDLPDVNDLAIEDIDTSNPFLYRQGK
ANAYFKRLRDEAPVHYQKNSAFGPFWSVTRYEDIVFVDKSHDLFSAEPQIILGDPPEGLSVEMFIAMDPPKHDVQRRAVQ
GVVAPKNLKEMEGLIRKRTGDVLDSLPLDTPFNWVPVVSKELTGRMLASLLDFPYDEREKLVGWSDRLSGASSATGGEFT
NEDVFFDDAADMAWAFSKLWRDKEARQKAGEEPGFDLISMLQSNEDTKDLINRPLEFIGNLALLIVGGNDTTRNSMSGGV
LALNQFPEQFEKLKANPKLIPNMVSEIIRWQTPLAYMRRVAKQDVELNGQTIKKGDRVLMWYASGNQDERKFENPEQFII
DRKDTRNHVSFGYGVHRCMGNRLAELQLRILWEELLPRFENIEVIGEPERVQSNFVRGYSKMMVKLTAKK

Sequences:

>Translated_470_residues
MSTSSSTSNDIQAKIINATSKVVPMHLQIKALKNLMKVKRKTIGTSRPQVHFVETDLPDVNDLAIEDIDTSNPFLYRQGK
ANAYFKRLRDEAPVHYQKNSAFGPFWSVTRYEDIVFVDKSHDLFSAEPQIILGDPPEGLSVEMFIAMDPPKHDVQRRAVQ
GVVAPKNLKEMEGLIRKRTGDVLDSLPLDTPFNWVPVVSKELTGRMLASLLDFPYDEREKLVGWSDRLSGASSATGGEFT
NEDVFFDDAADMAWAFSKLWRDKEARQKAGEEPGFDLISMLQSNEDTKDLINRPLEFIGNLALLIVGGNDTTRNSMSGGV
LALNQFPEQFEKLKANPKLIPNMVSEIIRWQTPLAYMRRVAKQDVELNGQTIKKGDRVLMWYASGNQDERKFENPEQFII
DRKDTRNHVSFGYGVHRCMGNRLAELQLRILWEELLPRFENIEVIGEPERVQSNFVRGYSKMMVKLTAKK
>Mature_469_residues
STSSSTSNDIQAKIINATSKVVPMHLQIKALKNLMKVKRKTIGTSRPQVHFVETDLPDVNDLAIEDIDTSNPFLYRQGKA
NAYFKRLRDEAPVHYQKNSAFGPFWSVTRYEDIVFVDKSHDLFSAEPQIILGDPPEGLSVEMFIAMDPPKHDVQRRAVQG
VVAPKNLKEMEGLIRKRTGDVLDSLPLDTPFNWVPVVSKELTGRMLASLLDFPYDEREKLVGWSDRLSGASSATGGEFTN
EDVFFDDAADMAWAFSKLWRDKEARQKAGEEPGFDLISMLQSNEDTKDLINRPLEFIGNLALLIVGGNDTTRNSMSGGVL
ALNQFPEQFEKLKANPKLIPNMVSEIIRWQTPLAYMRRVAKQDVELNGQTIKKGDRVLMWYASGNQDERKFENPEQFIID
RKDTRNHVSFGYGVHRCMGNRLAELQLRILWEELLPRFENIEVIGEPERVQSNFVRGYSKMMVKLTAKK

Specific function: Catalyzes the 8-methyl hydroxylation of linalool [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71982956, Length=212, Percent_Identity=24.0566037735849, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: =1.14.99.28 [H]

Molecular weight: Translated: 53473; Mature: 53342

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSSTSNDIQAKIINATSKVVPMHLQIKALKNLMKVKRKTIGTSRPQVHFVETDLPDV
CCCCCCCCCCCEEEEEECCCCEEEHEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
NDLAIEDIDTSNPFLYRQGKANAYFKRLRDEAPVHYQKNSAFGPFWSVTRYEDIVFVDKS
CCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECC
HDLFSAEPQIILGDPPEGLSVEMFIAMDPPKHDVQRRAVQGVVAPKNLKEMEGLIRKRTG
CCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DVLDSLPLDTPFNWVPVVSKELTGRMLASLLDFPYDEREKLVGWSDRLSGASSATGGEFT
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCCCCCCCCCC
NEDVFFDDAADMAWAFSKLWRDKEARQKAGEEPGFDLISMLQSNEDTKDLINRPLEFIGN
CCCEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
LALLIVGGNDTTRNSMSGGVLALNQFPEQFEKLKANPKLIPNMVSEIIRWQTPLAYMRRV
EEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHH
AKQDVELNGQTIKKGDRVLMWYASGNQDERKFENPEQFIIDRKDTRNHVSFGYGVHRCMG
HHHCCCCCCCEEECCCEEEEEEECCCCCHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHH
NRLAELQLRILWEELLPRFENIEVIGEPERVQSNFVRGYSKMMVKLTAKK
HHHHHHHHHHHHHHHCCHHCCEEEECCHHHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
STSSSTSNDIQAKIINATSKVVPMHLQIKALKNLMKVKRKTIGTSRPQVHFVETDLPDV
CCCCCCCCCCEEEEEECCCCEEEHEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
NDLAIEDIDTSNPFLYRQGKANAYFKRLRDEAPVHYQKNSAFGPFWSVTRYEDIVFVDKS
CCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECC
HDLFSAEPQIILGDPPEGLSVEMFIAMDPPKHDVQRRAVQGVVAPKNLKEMEGLIRKRTG
CCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DVLDSLPLDTPFNWVPVVSKELTGRMLASLLDFPYDEREKLVGWSDRLSGASSATGGEFT
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCCCCCCCCCC
NEDVFFDDAADMAWAFSKLWRDKEARQKAGEEPGFDLISMLQSNEDTKDLINRPLEFIGN
CCCEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
LALLIVGGNDTTRNSMSGGVLALNQFPEQFEKLKANPKLIPNMVSEIIRWQTPLAYMRRV
EEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHH
AKQDVELNGQTIKKGDRVLMWYASGNQDERKFENPEQFIIDRKDTRNHVSFGYGVHRCMG
HHHCCCCCCCEEECCCEEEEEEECCCCCHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHH
NRLAELQLRILWEELLPRFENIEVIGEPERVQSNFVRGYSKMMVKLTAKK
HHHHHHHHHHHHHHHCCHHCCEEEECCHHHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8376348; 2295633; 3813557; 2578028; 1610873; 12237225 [H]