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The map label for this gene is argS

Identifier: 110835103

GI number: 110835103

Start: 2562196

End: 2563950

Strand: Direct

Name: argS

Synonym: ABO_2242

Alternate gene names: 110835103

Gene position: 2562196-2563950 (Clockwise)

Preceding gene: 110835102

Following gene: 110835104

Centisome position: 82.12

GC content: 58.29

Gene sequence:

>1755_bases
ATGAAAGAACGCCTGATATCCCTTATTGAAAGCGCCTTGGACACCCTGATCACCGACGGTACTCTGCCCGCTGACGCCAA
GCGCCCAGTGCAAATTGACCGCACCCGGGACAAGAGCCACGGTGACTTTGCCACCAATATCGCGCTGATGCTGGCCAAAC
CCGCCGGCATGAAGCCTCGTGATCTAGCAGAAAAGCTGATCGCCGCTCTGCCCAACGACAGCGCCGTGGCCAAAGTCGAC
ATCGCCGGGCCCGGATTTATCAATTTCTTCCAGGCCGATGACTGGCTCACCGGCCTATTGGATTCCGCCCTGGCCGACGA
CTTTCTCGGCATTAGCCGGCCAGAGCAGCCCCAAACCGTGGTGGTGGACTACTCCTCACCCAATCTGGCCAAAGAAATGC
ACGTGGGCCACCTGCGCTCCACCATCATCGGCGACGCCGTGGTGCGTACCCTGGAATTTCTCGGTCACACCGTGATTCGC
CAGAATCATGTGGGCGATTGGGGCACCCAGTTCGGCATGCTTCTCGCTTATCTGGAGGAGCAAAAAACCGAAGAAGGTGA
GCGCGAGCTGAGCCGTGAACTGGCCAACCTGGAAACGTTCTACCGGGCCGCCAAACAACGCTTCGATGAATCCGACAGCT
TCGCCGACCGGGCCCGCGCCCTGGTGGTAAAACTGCAATCCGGCGACGACTACTGCCTGACCCTTTGGGCAGAGTTTAAT
CAGGTATCGCTAAGCCACTGCCAAGCGATCTACGACCGCTTAGGCGTCAGCCTGACACCGGCAGACGTGCACGGCGAAAG
CGCCTACAACGACGACCTGGCGCAAGTGGTGGCAGATCTGGACAGCAAAGGGCTGCTCAGTGAAAGCCAGGGCGCTCAAT
GTGTGTTTATGGACGCCTTCAAAAACAAGGAAGGCGAACCGCTGCCGGTGATTGTGCGTAAAGCCGACGGCGGCTACCTG
TATGCCACCAGCGACTTGGCAGCCCTGCGTTACCGCGCCAGCACCCTGCGGGCTGACCGCATGCTGTACTTTGTCGATCA
GCGCCAGGCACTTCATTTCCAACAAATGTTCACCTTGGCAAAACTGGCCGGCTTTGTGCCCGAACAGACCGAGCTGGCCC
ACATGGGCTTTGGCACCATGAACGGTCCAGATGGCCGCCCATTCAAGACCCGCGACGGTGGCACGGTTAAACTGGTAGAC
CTACTCGACGAAGCAGAGCAACGGGCCTTTGCCCTAGTGCAAGAAAAGAACCCGCAGCTGGACGACGAAGAATTACGCAA
CATTGCCCGCTCTGTGGGCATCGGCGCGGTAAAATACGCCGACTTGTCGAAAAACCGCAGCAGCGACTACATCTTCAACT
TCGAACAAATGCTCAGCTTTGAAGGTAACACCGCCCCCTACCTGCTTTACGCCTACACTCGTGTAGCCAGCGTATTCCGC
AAGGCCGAGCTGGACATGGCTAACGTAAGCGGCGACTTCCTGTTAAACGAAGACGCAGAACACACTCTCGCCGCGCGCCT
AGTGCAATTTGGTGAAGTACTGCAGAACGTAGCCGACAAGGGCCAACCGCACCTGCTCAGCGCCTACCTGTACGATGTGG
CCGGCCTGTTTTCCAGTTTCTATGAGCATTGCCCCATCCTCAGCAGCGAAGATGAGCGCATTCGGCAAAGCCGCCTTAAG
TTGGCCGCCCTCACCGCCCGCACTCTCAAACACGGCATGGAATTGCTGGGCCTGAGCCCACTGGAGCGCATGTAA

Upstream 100 bases:

>100_bases
CAGTGTCGGCCATCAGACATCCTGCGCATGCGTAAGCATGGCTTTTCCCGTACAATCGCCGGCCAGTTAAACGGCCCAGA
GCCCTCCACAAAAGAATGTC

Downstream 100 bases:

>100_bases
TGGCGAAGAACACCCGGCGCGGCGCCAGCCGCGGCCCTGCCCGCAAAAAGACACCCCAGCGCCAGGTACCCGGCTGGGTG
TGGTTGTTTACAGGTCTCAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKERLISLIESALDTLITDGTLPADAKRPVQIDRTRDKSHGDFATNIALMLAKPAGMKPRDLAEKLIAALPNDSAVAKVD
IAGPGFINFFQADDWLTGLLDSALADDFLGISRPEQPQTVVVDYSSPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHTVIR
QNHVGDWGTQFGMLLAYLEEQKTEEGERELSRELANLETFYRAAKQRFDESDSFADRARALVVKLQSGDDYCLTLWAEFN
QVSLSHCQAIYDRLGVSLTPADVHGESAYNDDLAQVVADLDSKGLLSESQGAQCVFMDAFKNKEGEPLPVIVRKADGGYL
YATSDLAALRYRASTLRADRMLYFVDQRQALHFQQMFTLAKLAGFVPEQTELAHMGFGTMNGPDGRPFKTRDGGTVKLVD
LLDEAEQRAFALVQEKNPQLDDEELRNIARSVGIGAVKYADLSKNRSSDYIFNFEQMLSFEGNTAPYLLYAYTRVASVFR
KAELDMANVSGDFLLNEDAEHTLAARLVQFGEVLQNVADKGQPHLLSAYLYDVAGLFSSFYEHCPILSSEDERIRQSRLK
LAALTARTLKHGMELLGLSPLERM

Sequences:

>Translated_584_residues
MKERLISLIESALDTLITDGTLPADAKRPVQIDRTRDKSHGDFATNIALMLAKPAGMKPRDLAEKLIAALPNDSAVAKVD
IAGPGFINFFQADDWLTGLLDSALADDFLGISRPEQPQTVVVDYSSPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHTVIR
QNHVGDWGTQFGMLLAYLEEQKTEEGERELSRELANLETFYRAAKQRFDESDSFADRARALVVKLQSGDDYCLTLWAEFN
QVSLSHCQAIYDRLGVSLTPADVHGESAYNDDLAQVVADLDSKGLLSESQGAQCVFMDAFKNKEGEPLPVIVRKADGGYL
YATSDLAALRYRASTLRADRMLYFVDQRQALHFQQMFTLAKLAGFVPEQTELAHMGFGTMNGPDGRPFKTRDGGTVKLVD
LLDEAEQRAFALVQEKNPQLDDEELRNIARSVGIGAVKYADLSKNRSSDYIFNFEQMLSFEGNTAPYLLYAYTRVASVFR
KAELDMANVSGDFLLNEDAEHTLAARLVQFGEVLQNVADKGQPHLLSAYLYDVAGLFSSFYEHCPILSSEDERIRQSRLK
LAALTARTLKHGMELLGLSPLERM
>Mature_584_residues
MKERLISLIESALDTLITDGTLPADAKRPVQIDRTRDKSHGDFATNIALMLAKPAGMKPRDLAEKLIAALPNDSAVAKVD
IAGPGFINFFQADDWLTGLLDSALADDFLGISRPEQPQTVVVDYSSPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHTVIR
QNHVGDWGTQFGMLLAYLEEQKTEEGERELSRELANLETFYRAAKQRFDESDSFADRARALVVKLQSGDDYCLTLWAEFN
QVSLSHCQAIYDRLGVSLTPADVHGESAYNDDLAQVVADLDSKGLLSESQGAQCVFMDAFKNKEGEPLPVIVRKADGGYL
YATSDLAALRYRASTLRADRMLYFVDQRQALHFQQMFTLAKLAGFVPEQTELAHMGFGTMNGPDGRPFKTRDGGTVKLVD
LLDEAEQRAFALVQEKNPQLDDEELRNIARSVGIGAVKYADLSKNRSSDYIFNFEQMLSFEGNTAPYLLYAYTRVASVFR
KAELDMANVSGDFLLNEDAEHTLAARLVQFGEVLQNVADKGQPHLLSAYLYDVAGLFSSFYEHCPILSSEDERIRQSRLK
LAALTARTLKHGMELLGLSPLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=576, Percent_Identity=38.3680555555556, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI197100773, Length=561, Percent_Identity=31.1942959001783, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=57.167530224525, Blast_Score=653, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=577, Percent_Identity=37.261698440208, Blast_Score=351, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI71985068, Length=545, Percent_Identity=37.7981651376147, Blast_Score=341, Evalue=7e-94,
Organism=Caenorhabditis elegans, GI17532153, Length=491, Percent_Identity=25.4582484725051, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=569, Percent_Identity=33.0404217926186, Blast_Score=256, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6321883, Length=558, Percent_Identity=30.6451612903226, Blast_Score=226, Evalue=7e-60,
Organism=Drosophila melanogaster, GI18859963, Length=562, Percent_Identity=38.4341637010676, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=33.8809034907598, Blast_Score=211, Evalue=1e-54,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ALCBS (Q0VMA8)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693962.1
- ProteinModelPortal:   Q0VMA8
- SMR:   Q0VMA8
- STRING:   Q0VMA8
- GeneID:   4213484
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2242
- NMPDR:   fig|393595.12.peg.2242
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   Q0VMA8
- ProtClustDB:   PRK01611
- BioCyc:   ABOR393595:ABO_2242-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64883; Mature: 64883

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERLISLIESALDTLITDGTLPADAKRPVQIDRTRDKSHGDFATNIALMLAKPAGMKPR
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHEEECCCCCCHH
DLAEKLIAALPNDSAVAKVDIAGPGFINFFQADDWLTGLLDSALADDFLGISRPEQPQTV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VVDYSSPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHTVIRQNHVGDWGTQFGMLLAYLEE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QKTEEGERELSRELANLETFYRAAKQRFDESDSFADRARALVVKLQSGDDYCLTLWAEFN
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEEECCCCEEEEEEHHHC
QVSLSHCQAIYDRLGVSLTPADVHGESAYNDDLAQVVADLDSKGLLSESQGAQCVFMDAF
HHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHH
KNKEGEPLPVIVRKADGGYLYATSDLAALRYRASTLRADRMLYFVDQRQALHFQQMFTLA
CCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHH
KLAGFVPEQTELAHMGFGTMNGPDGRPFKTRDGGTVKLVDLLDEAEQRAFALVQEKNPQL
HHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC
DDEELRNIARSVGIGAVKYADLSKNRSSDYIFNFEQMLSFEGNTAPYLLYAYTRVASVFR
CHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHH
KAELDMANVSGDFLLNEDAEHTLAARLVQFGEVLQNVADKGQPHLLSAYLYDVAGLFSSF
HHHCCHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YEHCPILSSEDERIRQSRLKLAALTARTLKHGMELLGLSPLERM
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MKERLISLIESALDTLITDGTLPADAKRPVQIDRTRDKSHGDFATNIALMLAKPAGMKPR
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHEEECCCCCCHH
DLAEKLIAALPNDSAVAKVDIAGPGFINFFQADDWLTGLLDSALADDFLGISRPEQPQTV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VVDYSSPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHTVIRQNHVGDWGTQFGMLLAYLEE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QKTEEGERELSRELANLETFYRAAKQRFDESDSFADRARALVVKLQSGDDYCLTLWAEFN
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEEECCCCEEEEEEHHHC
QVSLSHCQAIYDRLGVSLTPADVHGESAYNDDLAQVVADLDSKGLLSESQGAQCVFMDAF
HHHHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHH
KNKEGEPLPVIVRKADGGYLYATSDLAALRYRASTLRADRMLYFVDQRQALHFQQMFTLA
CCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHH
KLAGFVPEQTELAHMGFGTMNGPDGRPFKTRDGGTVKLVDLLDEAEQRAFALVQEKNPQL
HHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC
DDEELRNIARSVGIGAVKYADLSKNRSSDYIFNFEQMLSFEGNTAPYLLYAYTRVASVFR
CHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHH
KAELDMANVSGDFLLNEDAEHTLAARLVQFGEVLQNVADKGQPHLLSAYLYDVAGLFSSF
HHHCCHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YEHCPILSSEDERIRQSRLKLAALTARTLKHGMELLGLSPLERM
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA