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The map label for this gene is pldA [H]

Identifier: 110834965

GI number: 110834965

Start: 2409879

End: 2410916

Strand: Direct

Name: pldA [H]

Synonym: ABO_2104

Alternate gene names: 110834965

Gene position: 2409879-2410916 (Clockwise)

Preceding gene: 110834964

Following gene: 110834966

Centisome position: 77.24

GC content: 50.87

Gene sequence:

>1038_bases
ATGCATATCCGCCTTATGTTCGCCCTAGCGCTGGCCAGCTCCCTTCTTTGCGCCGAGGAGCCGGCCAATAACGATCCTCC
TGTACCCGACAGCCCAGCCATCAACATGACAGAAGAGCAAAAGCTCAATAACTGTCTGTTACGCAGTGCCCAGACCGCTA
ATGGCAATGTAACACTGCACGAAATGCGCGGTTGGTGTACGAACGGCGAAGAACAAGAGAGAATCAGTAGCCATGAGAAC
GCCCTGCGAGCCAGGCTGGCACTGGAAAATACCACCCGCGGCAATCCCTTTGTCATCACCCCTCATCGCCGAAACTACCT
GATGCCGTATAGTTACTGGTCCAATCGGCAGTGGAACGACCCCACCAAGAAGGACAGTGATCTACAACCCTCTGAGGTCA
AATTTCAGTTATCGCTGAAAGCCCCTATCAAAGAAAAGATTTTCGATGACATTACCCTTTGGATGGCCTTTACCGGCACG
TTCTATTGGCAGGCTTACAACAGTGACCTCTCGGCCCCATTCCGTGAAGCCAATTACGAGCCGGAATTATTCATTACCAA
ACCGATTGATTGGCAAATCGGACCTCTAGATTCGGAGCTATTGGCGCTAGGGTTCAACCATCAGTCCAACGGCCAGGATG
TGCCCGTTTCACGTAGCTGGAACCGTATCTTCATGAACTATGTGTTCAAGACAGGGGATTACTACTGGTCCTTCAAACCT
TGGTATCGCATTCCTGAAGATAAAAAAGACTCCCCCACAGATGCCGGCGGTGACGACAACCCGGATATCGAAAAGTACAT
GGGCAATTTCGAACTGGAAGTCGCACACCCATTCGGCAACCACGTGGTCGAACTGATGCTACGCAACAATCTACGTTCGG
AGAATAAGGGCGCAGGCCGCCTCAATTACTCATTCCCGCTAAGCAAACGCTTCAAAGGCTTGGTGCAGGTTTTCTCCGGG
TACGGGGATTCACTGATTAATTACGACAATTATGAGAACCGCTACAGCTTCGGGATCCTGTTGACGGATTCTCTATAG

Upstream 100 bases:

>100_bases
TACCGGTCATGCTGGAAGAGCAGGCACGCGCCATGAGTGATGAAGAAGCCCTGTCACTATAACATTTAGCTCCACTACTC
CTCGCCACAGGAAGGCCCTC

Downstream 100 bases:

>100_bases
AGGCAGCCGCGAGCCACACGTTTTAAATAAGACACCAAAGGCTCTCTTGAAAGTGCACACAGATTGCAGCGCAGCCAAGA
GAGCGTTTCGGAGTCAACGG

Product: outer membrane phospholipase A

Products: NA

Alternate protein names: Detergent-resistant phospholipase A; DR-phospholipase A; Outer membrane phospholipase A; OM PLA; Phosphatidylcholine 1-acylhydrolase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MHIRLMFALALASSLLCAEEPANNDPPVPDSPAINMTEEQKLNNCLLRSAQTANGNVTLHEMRGWCTNGEEQERISSHEN
ALRARLALENTTRGNPFVITPHRRNYLMPYSYWSNRQWNDPTKKDSDLQPSEVKFQLSLKAPIKEKIFDDITLWMAFTGT
FYWQAYNSDLSAPFREANYEPELFITKPIDWQIGPLDSELLALGFNHQSNGQDVPVSRSWNRIFMNYVFKTGDYYWSFKP
WYRIPEDKKDSPTDAGGDDNPDIEKYMGNFELEVAHPFGNHVVELMLRNNLRSENKGAGRLNYSFPLSKRFKGLVQVFSG
YGDSLINYDNYENRYSFGILLTDSL

Sequences:

>Translated_345_residues
MHIRLMFALALASSLLCAEEPANNDPPVPDSPAINMTEEQKLNNCLLRSAQTANGNVTLHEMRGWCTNGEEQERISSHEN
ALRARLALENTTRGNPFVITPHRRNYLMPYSYWSNRQWNDPTKKDSDLQPSEVKFQLSLKAPIKEKIFDDITLWMAFTGT
FYWQAYNSDLSAPFREANYEPELFITKPIDWQIGPLDSELLALGFNHQSNGQDVPVSRSWNRIFMNYVFKTGDYYWSFKP
WYRIPEDKKDSPTDAGGDDNPDIEKYMGNFELEVAHPFGNHVVELMLRNNLRSENKGAGRLNYSFPLSKRFKGLVQVFSG
YGDSLINYDNYENRYSFGILLTDSL
>Mature_345_residues
MHIRLMFALALASSLLCAEEPANNDPPVPDSPAINMTEEQKLNNCLLRSAQTANGNVTLHEMRGWCTNGEEQERISSHEN
ALRARLALENTTRGNPFVITPHRRNYLMPYSYWSNRQWNDPTKKDSDLQPSEVKFQLSLKAPIKEKIFDDITLWMAFTGT
FYWQAYNSDLSAPFREANYEPELFITKPIDWQIGPLDSELLALGFNHQSNGQDVPVSRSWNRIFMNYVFKTGDYYWSFKP
WYRIPEDKKDSPTDAGGDDNPDIEKYMGNFELEVAHPFGNHVVELMLRNNLRSENKGAGRLNYSFPLSKRFKGLVQVFSG
YGDSLINYDNYENRYSFGILLTDSL

Specific function: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities [H]

COG id: COG2829

COG function: function code M; Outer membrane phospholipase A

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein. Note=One of the very few enzymes located there (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phospholipase A1 family [H]

Homologues:

Organism=Escherichia coli, GI2367300, Length=258, Percent_Identity=35.6589147286822, Blast_Score=154, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003187 [H]

Pfam domain/function: PF02253 PLA1 [H]

EC number: =3.1.1.32; =3.1.1.4 [H]

Molecular weight: Translated: 39799; Mature: 39799

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIRLMFALALASSLLCAEEPANNDPPVPDSPAINMTEEQKLNNCLLRSAQTANGNVTLH
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
EMRGWCTNGEEQERISSHENALRARLALENTTRGNPFVITPHRRNYLMPYSYWSNRQWND
ECCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCCEEECCCCCCCCCCCC
PTKKDSDLQPSEVKFQLSLKAPIKEKIFDDITLWMAFTGTFYWQAYNSDLSAPFREANYE
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHEEEHHHCEEEEEEECCCCCCCHHHCCCC
PELFITKPIDWQIGPLDSELLALGFNHQSNGQDVPVSRSWNRIFMNYVFKTGDYYWSFKP
CCEEEECCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHEEEHEEECCCEEEECCC
WYRIPEDKKDSPTDAGGDDNPDIEKYMGNFELEVAHPFGNHVVELMLRNNLRSENKGAGR
CEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCE
LNYSFPLSKRFKGLVQVFSGYGDSLINYDNYENRYSFGILLTDSL
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MHIRLMFALALASSLLCAEEPANNDPPVPDSPAINMTEEQKLNNCLLRSAQTANGNVTLH
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
EMRGWCTNGEEQERISSHENALRARLALENTTRGNPFVITPHRRNYLMPYSYWSNRQWND
ECCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCCEEECCCCCCCCCCCC
PTKKDSDLQPSEVKFQLSLKAPIKEKIFDDITLWMAFTGTFYWQAYNSDLSAPFREANYE
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHEEEHHHCEEEEEEECCCCCCCHHHCCCC
PELFITKPIDWQIGPLDSELLALGFNHQSNGQDVPVSRSWNRIFMNYVFKTGDYYWSFKP
CCEEEECCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHEEEHEEECCCEEEECCC
WYRIPEDKKDSPTDAGGDDNPDIEKYMGNFELEVAHPFGNHVVELMLRNNLRSENKGAGR
CEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCE
LNYSFPLSKRFKGLVQVFSGYGDSLINYDNYENRYSFGILLTDSL
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8300539 [H]