Click here to switch to the map view.

The map label for this gene is endA [H]

Identifier: 110834958

GI number: 110834958

Start: 2402672

End: 2403307

Strand: Direct

Name: endA [H]

Synonym: ABO_2097

Alternate gene names: 110834958

Gene position: 2402672-2403307 (Clockwise)

Preceding gene: 110834957

Following gene: 110834960

Centisome position: 77.01

GC content: 51.73

Gene sequence:

>636_bases
ATGCGGAAAATTATACTGACGCTGCTGGCAACGTGTTTGCCGGTTACCGCCAGCTACGCCGGTGGCATGGATACATTGTT
CCTCGAACAAGTCTACCCTAATGGCGGCTCTACTCTTTATTGTCAGGAACCTTTCCAACTCGGTGATCGCATTTTAGTAA
CGCAGATTTACGATGAGCGCCGTCTAGCACAACACTTTGGTTGCAGAAGTAGCCGTCTTTGCAGAAACAATCCGCAGTTC
ACTGATATTTACCAGGACCGCCATGCCCTTTTCCCCGTTACCCGCCTCGCCGAACTAGATCGTCGGCGGACCCTGTTTGG
CGATTTACCCGATACAACGAATAAAAATGCTCATTGCGGTTACAAACAATCTTTCCAAGTGTTCGAGCCCCCGGTAAACG
CCAAAGGTGACGTGGCACGGGCCATGCTCTATCTCCACGAGCGTTACGAATTGCCCCTGCTAGGCACGCTGGAAATGTAC
CAACGCTGGAGCAGGGAGGACCCCGTTACTGACGAAGAGCGCCAACGCAATAATGTGATTGAAAAACTGCAGGGTAACCG
CAACCCCTTCATTGATAATCCAGCCCAAGCACAACGCCTACAGGGCAGCTCACCGCTGAACATGCAGTTTCCATAG

Upstream 100 bases:

>100_bases
CATAGGCACCAGCTATCTGCCAAGCATACATTGCAGATAGCCGTCATCATGGCCTTGAGGGCTAATATGGTAATAAGAAG
AATGTGACAGGATTCACAAC

Downstream 100 bases:

>100_bases
AGGGGTTCAAAGTTGAAACGTGAACACTTTACTCAACGCTTTTAACGCAAGAGGCCGCACCCAAACACAGGGCGCGGCCT
CTTGATTTCAGTACGGGGAA

Product: endonuclease I

Products: NA

Alternate protein names: Endonuclease I; Endo I [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MRKIILTLLATCLPVTASYAGGMDTLFLEQVYPNGGSTLYCQEPFQLGDRILVTQIYDERRLAQHFGCRSSRLCRNNPQF
TDIYQDRHALFPVTRLAELDRRRTLFGDLPDTTNKNAHCGYKQSFQVFEPPVNAKGDVARAMLYLHERYELPLLGTLEMY
QRWSREDPVTDEERQRNNVIEKLQGNRNPFIDNPAQAQRLQGSSPLNMQFP

Sequences:

>Translated_211_residues
MRKIILTLLATCLPVTASYAGGMDTLFLEQVYPNGGSTLYCQEPFQLGDRILVTQIYDERRLAQHFGCRSSRLCRNNPQF
TDIYQDRHALFPVTRLAELDRRRTLFGDLPDTTNKNAHCGYKQSFQVFEPPVNAKGDVARAMLYLHERYELPLLGTLEMY
QRWSREDPVTDEERQRNNVIEKLQGNRNPFIDNPAQAQRLQGSSPLNMQFP
>Mature_211_residues
MRKIILTLLATCLPVTASYAGGMDTLFLEQVYPNGGSTLYCQEPFQLGDRILVTQIYDERRLAQHFGCRSSRLCRNNPQF
TDIYQDRHALFPVTRLAELDRRRTLFGDLPDTTNKNAHCGYKQSFQVFEPPVNAKGDVARAMLYLHERYELPLLGTLEMY
QRWSREDPVTDEERQRNNVIEKLQGNRNPFIDNPAQAQRLQGSSPLNMQFP

Specific function: Has double-strand break activity [H]

COG id: COG2356

COG function: function code L; Endonuclease I

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the endA/nucM nuclease family [H]

Homologues:

Organism=Escherichia coli, GI1789314, Length=129, Percent_Identity=29.4573643410853, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007346 [H]

Pfam domain/function: PF04231 Endonuclease_1 [H]

EC number: =3.1.21.1 [H]

Molecular weight: Translated: 24401; Mature: 24401

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIILTLLATCLPVTASYAGGMDTLFLEQVYPNGGSTLYCQEPFQLGDRILVTQIYDER
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHCCCEEEEHHHHHHH
RLAQHFGCRSSRLCRNNPQFTDIYQDRHALFPVTRLAELDRRRTLFGDLPDTTNKNAHCG
HHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YKQSFQVFEPPVNAKGDVARAMLYLHERYELPLLGTLEMYQRWSREDPVTDEERQRNNVI
CCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
EKLQGNRNPFIDNPAQAQRLQGSSPLNMQFP
HHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRKIILTLLATCLPVTASYAGGMDTLFLEQVYPNGGSTLYCQEPFQLGDRILVTQIYDER
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHCCCEEEEHHHHHHH
RLAQHFGCRSSRLCRNNPQFTDIYQDRHALFPVTRLAELDRRRTLFGDLPDTTNKNAHCG
HHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YKQSFQVFEPPVNAKGDVARAMLYLHERYELPLLGTLEMYQRWSREDPVTDEERQRNNVI
CCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
EKLQGNRNPFIDNPAQAQRLQGSSPLNMQFP
HHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7867949; 9278503; 4955462; 8113204 [H]