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The map label for this gene is fur [H]

Identifier: 110636271

GI number: 110636271

Start: 4253210

End: 4253638

Strand: Reverse

Name: fur [H]

Synonym: Meso_3947

Alternate gene names: 110636271

Gene position: 4253638-4253210 (Counterclockwise)

Preceding gene: 110636275

Following gene: 110636270

Centisome position: 96.4

GC content: 57.58

Gene sequence:

>429_bases
ATGAGTGAAACGGTGCCGAACAGGGTGAAATACGAGGAAAAGCTCCGCCGCGCCGGGATCCGGATCACTCGCCCCCGGCA
GGTGATCCTGAGCATTCTCGCGCAGACGGAAGACCACCCGGACGCGATGGAGATTTTCAGCCGCGCCTCAGAGATTGATC
CCAGCATCTCACTTTCCACAGTCTATCGCACCATGAAACTGCTCGAGGAACTTGGTGCCATCCACCGCCACGCATTCGAG
GGCGGGCGGGCCCGCTTCGAGCAGGCAAGCCAACATCATGACCATTTGATCGATATCGATACCGGTGATGTGATAGAGTT
CCATTCAACAAAAATCGAGGCGCTGCAGGACGAGATCGCCCGTTCGCTGGGTTACGATATCGTTCATCATAGGCTGGAGC
TTTACGGCAGGAAGCGGCGACGCCGCTAG

Upstream 100 bases:

>100_bases
CTGTGCCGCTGCCTGTCAACAGGTTTGCGCTCGCGTGCGGCGGTGTTAAAGACCCGGCTGCGACTTTGCAACAAAGGCCG
ATTTAGCGCATAGTCTTATA

Downstream 100 bases:

>100_bases
GCTACCGAAAAGCATGGGTTACTCTGCACGCCAGCGCACACAAGATGGGTCTGTCTTCATATGGAAAAAGCTGACATCGG
TCTTATCGGTCTTGGGACCA

Product: FUR family manganese uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSETVPNRVKYEEKLRRAGIRITRPRQVILSILAQTEDHPDAMEIFSRASEIDPSISLSTVYRTMKLLEELGAIHRHAFE
GGRARFEQASQHHDHLIDIDTGDVIEFHSTKIEALQDEIARSLGYDIVHHRLELYGRKRRRR

Sequences:

>Translated_142_residues
MSETVPNRVKYEEKLRRAGIRITRPRQVILSILAQTEDHPDAMEIFSRASEIDPSISLSTVYRTMKLLEELGAIHRHAFE
GGRARFEQASQHHDHLIDIDTGDVIEFHSTKIEALQDEIARSLGYDIVHHRLELYGRKRRRR
>Mature_141_residues
SETVPNRVKYEEKLRRAGIRITRPRQVILSILAQTEDHPDAMEIFSRASEIDPSISLSTVYRTMKLLEELGAIHRHAFEG
GRARFEQASQHHDHLIDIDTGDVIEFHSTKIEALQDEIARSLGYDIVHHRLELYGRKRRRR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=124, Percent_Identity=42.741935483871, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16552; Mature: 16421

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETVPNRVKYEEKLRRAGIRITRPRQVILSILAQTEDHPDAMEIFSRASEIDPSISLST
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHH
VYRTMKLLEELGAIHRHAFEGGRARFEQASQHHDHLIDIDTGDVIEFHSTKIEALQDEIA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHHHHHHH
RSLGYDIVHHRLELYGRKRRRR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SETVPNRVKYEEKLRRAGIRITRPRQVILSILAQTEDHPDAMEIFSRASEIDPSISLST
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHH
VYRTMKLLEELGAIHRHAFEGGRARFEQASQHHDHLIDIDTGDVIEFHSTKIEALQDEIA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHHHHHHH
RSLGYDIVHHRLELYGRKRRRR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA