Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 110636228

GI number: 110636228

Start: 4206086

End: 4207243

Strand: Reverse

Name: yccK [H]

Synonym: Meso_3904

Alternate gene names: 110636228

Gene position: 4207243-4206086 (Counterclockwise)

Preceding gene: 110636230

Following gene: 110636227

Centisome position: 95.35

GC content: 64.68

Gene sequence:

>1158_bases
ATGAAGAAAGAAGACATTTCCACAATCGGCCGCCGTAGTTTTCTCGGCGTGGCGGCAACGATGGCGGTAGCTCCTGTCCT
CATTGGCGCCACTTCCAAGGCGTGGGCGCAGGCTGGCGGCCCGGATGGCTCCATAGCAGCGTCGTCGAGCAATTCCCGCA
ACCTTGGAGCGCTGGAGGTTTCGAGCGTCGGGCTGGGCGTCCAGAACATGGCCCGTACCTACCAGACGACGATCCCGTCG
CGGCCGGAGATGATCAACATCATCCGGACGGCCCATGAGCGCGGCGTTACCTTCTTCGACACCGCCGAGGCCTATGGCCC
GCACGAGTGCGAGCGGATTCTCGGCGAAGCTATCGCGCCGTTCCGCGACGAGGTCGTGATCACCTCGAAATTCGGCTGGA
ACATCGATCTGGACACCGGCGAGCGTCGACCGGGACTCATCAGCCGCCCGGACCACATCAAGCTCGCGGTCGAAGGCATG
CTCGAACGCCTGCGCACCGATCGCGTCGATCTTCTCTACCAGCACCGCGTCGACCCGGAGGTACCGATCGAGGACGTCGC
CGGAGCAATCAAGGACCTCATGGACGAGGGCAAGGTGCTGCATTGGGGCCTCTCCGAGATGGGGCTCAACACGTTGCGCC
GCGCCCACGCCGCCCTTCCCGTATCGGCGGTCCAGAGCGAGTATTCGATGCTGTGGCGCGGTCCGGAAGACGAGGTGCTT
TCCGTTTGCGAGGAACTGGGCATCGGCTTCGTGCCGTGGAGCCCGCTCGGGGTCGGCTTCTTGACGGGAGCCATCGACGA
GCGGACGCGTTTCGCGGAGGGAGACATTCGCGGAATCGAGTCGCGCTTCTCGCCCGATAACCTGCCGGCGAACCTGGCGC
TCGTGAGATTGCTAGGCGAATGGGCCGACAGGAAGCAGGCCACCCGGGCACAGATCGCGCTGGCATGGCTGATGGCGCAA
AAGCCCTGGATCGTTCCGATCCCCGGCACGACGCAGATGGCGCACTTGCTCGAGAACATCGGCGCGGCTTCGGTAAGCTT
CACGCCCGAGGAAATCGGCGAGCTCAACTCCGCGGTCGCAGCGATCGAGGTGCGCGGCCAGCGCCTGCCCGACGCCGTGC
TGGCATTCTCGAACGTCGAGGCGCCTGAGAGGAATTGA

Upstream 100 bases:

>100_bases
ATCGGCCATAAACGTCCGGAACAAGGTCGTTTCGGCCGACCTTGACCCGAGGCGACCGGCCAGCCCCGTGCAGGTGATCA
TCATCGAAGGACCCATGGAC

Downstream 100 bases:

>100_bases
AGGGATTATCGCAATGGAACGCAGATATCTCGGCGATCTCGAGGTCTCGGCCCTTGGACTCGGATGCATGGGCCTGAGCC
ACGGCTATGGTCCGGCCGTC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKKEDISTIGRRSFLGVAATMAVAPVLIGATSKAWAQAGGPDGSIAASSSNSRNLGALEVSSVGLGVQNMARTYQTTIPS
RPEMINIIRTAHERGVTFFDTAEAYGPHECERILGEAIAPFRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGM
LERLRTDRVDLLYQHRVDPEVPIEDVAGAIKDLMDEGKVLHWGLSEMGLNTLRRAHAALPVSAVQSEYSMLWRGPEDEVL
SVCEELGIGFVPWSPLGVGFLTGAIDERTRFAEGDIRGIESRFSPDNLPANLALVRLLGEWADRKQATRAQIALAWLMAQ
KPWIVPIPGTTQMAHLLENIGAASVSFTPEEIGELNSAVAAIEVRGQRLPDAVLAFSNVEAPERN

Sequences:

>Translated_385_residues
MKKEDISTIGRRSFLGVAATMAVAPVLIGATSKAWAQAGGPDGSIAASSSNSRNLGALEVSSVGLGVQNMARTYQTTIPS
RPEMINIIRTAHERGVTFFDTAEAYGPHECERILGEAIAPFRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGM
LERLRTDRVDLLYQHRVDPEVPIEDVAGAIKDLMDEGKVLHWGLSEMGLNTLRRAHAALPVSAVQSEYSMLWRGPEDEVL
SVCEELGIGFVPWSPLGVGFLTGAIDERTRFAEGDIRGIESRFSPDNLPANLALVRLLGEWADRKQATRAQIALAWLMAQ
KPWIVPIPGTTQMAHLLENIGAASVSFTPEEIGELNSAVAAIEVRGQRLPDAVLAFSNVEAPERN
>Mature_385_residues
MKKEDISTIGRRSFLGVAATMAVAPVLIGATSKAWAQAGGPDGSIAASSSNSRNLGALEVSSVGLGVQNMARTYQTTIPS
RPEMINIIRTAHERGVTFFDTAEAYGPHECERILGEAIAPFRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGM
LERLRTDRVDLLYQHRVDPEVPIEDVAGAIKDLMDEGKVLHWGLSEMGLNTLRRAHAALPVSAVQSEYSMLWRGPEDEVL
SVCEELGIGFVPWSPLGVGFLTGAIDERTRFAEGDIRGIESRFSPDNLPANLALVRLLGEWADRKQATRAQIALAWLMAQ
KPWIVPIPGTTQMAHLLENIGAASVSFTPEEIGELNSAVAAIEVRGQRLPDAVLAFSNVEAPERN

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=322, Percent_Identity=29.8136645962733, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=29.6774193548387, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=29.6774193548387, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=28.3950617283951, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=28.3870967741935, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=29.126213592233, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI223718702, Length=248, Percent_Identity=26.2096774193548, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI41152114, Length=121, Percent_Identity=31.404958677686, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI41327764, Length=141, Percent_Identity=28.3687943262411, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081735, Length=316, Percent_Identity=32.9113924050633, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789375, Length=300, Percent_Identity=28.3333333333333, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788070, Length=297, Percent_Identity=28.6195286195286, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787674, Length=317, Percent_Identity=28.7066246056782, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788081, Length=285, Percent_Identity=24.2105263157895, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994888, Length=189, Percent_Identity=32.8042328042328, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789199, Length=334, Percent_Identity=26.0479041916168, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=26.1016949152542, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=294, Percent_Identity=26.530612244898, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325169, Length=304, Percent_Identity=28.2894736842105, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=27.5590551181102, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=369, Percent_Identity=25.4742547425474, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=311, Percent_Identity=27.0096463022508, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640980, Length=330, Percent_Identity=24.5454545454545, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45549126, Length=330, Percent_Identity=24.5454545454545, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41875; Mature: 41875

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEDISTIGRRSFLGVAATMAVAPVLIGATSKAWAQAGGPDGSIAASSSNSRNLGALEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCCEEEE
SSVGLGVQNMARTYQTTIPSRPEMINIIRTAHERGVTFFDTAEAYGPHECERILGEAIAP
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECHHCCCHHHHHHHHHHHHCC
FRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGMLERLRTDRVDLLYQHRVDPE
CCCCEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPIEDVAGAIKDLMDEGKVLHWGLSEMGLNTLRRAHAALPVSAVQSEYSMLWRGPEDEVL
CCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
SVCEELGIGFVPWSPLGVGFLTGAIDERTRFAEGDIRGIESRFSPDNLPANLALVRLLGE
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
WADRKQATRAQIALAWLMAQKPWIVPIPGTTQMAHLLENIGAASVSFTPEEIGELNSAVA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEECCHHHHHHHHHHHH
AIEVRGQRLPDAVLAFSNVEAPERN
HEEECCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKEDISTIGRRSFLGVAATMAVAPVLIGATSKAWAQAGGPDGSIAASSSNSRNLGALEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCCEEEE
SSVGLGVQNMARTYQTTIPSRPEMINIIRTAHERGVTFFDTAEAYGPHECERILGEAIAP
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECHHCCCHHHHHHHHHHHHCC
FRDEVVITSKFGWNIDLDTGERRPGLISRPDHIKLAVEGMLERLRTDRVDLLYQHRVDPE
CCCCEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VPIEDVAGAIKDLMDEGKVLHWGLSEMGLNTLRRAHAALPVSAVQSEYSMLWRGPEDEVL
CCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
SVCEELGIGFVPWSPLGVGFLTGAIDERTRFAEGDIRGIESRFSPDNLPANLALVRLLGE
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
WADRKQATRAQIALAWLMAQKPWIVPIPGTTQMAHLLENIGAASVSFTPEEIGELNSAVA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEECCHHHHHHHHHHHH
AIEVRGQRLPDAVLAFSNVEAPERN
HEEECCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]