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The map label for this gene is yccK [H]

Identifier: 110636227

GI number: 110636227

Start: 4205089

End: 4206072

Strand: Reverse

Name: yccK [H]

Synonym: Meso_3903

Alternate gene names: 110636227

Gene position: 4206072-4205089 (Counterclockwise)

Preceding gene: 110636228

Following gene: 110636226

Centisome position: 95.32

GC content: 63.41

Gene sequence:

>984_bases
ATGGAACGCAGATATCTCGGCGATCTCGAGGTCTCGGCCCTTGGACTCGGATGCATGGGCCTGAGCCACGGCTATGGTCC
GGCCGTCGAGAAGAAAGACGGTATCGCTCTGATCCGCGCAGCGGTCGAACGGGGCGTGACCTTTTTCGACACGGCCGAAG
TCTATGGCCCGTTCACCAACGAGGAGCTGGTCGGCGAAGCGCTGGAGCCGGTCCGTGACCGCGTGGTGATCGCCACGAAG
TTCGGCTTCGACATCGGAGGCGACAACAAGGAACGTCCGCTCAACAGCCGCCCCGAGCGCATCAAAAAGGTGGCCGACGC
CAGCCTCAAGCGCCTTCGGACCGATCGCATCGACCTGTTCTACCAGCATCGCGTCGATCCTGATGTGCCGATCGAGGATG
TCGCGGGCGCCGTCAGGGACCTGATCGCGGAAGGCAAGGTCAAGCATTTCGGGCTGTCGGAAGCGGGCGTGGGCACGATC
CGGCGCGCTCATGCGGTCCAGCCGGTGGCGGCGCTTCAGAGCGAATACTCACTCTGGTGGCGCGAGCCGGAGAAGGATGT
GCTGCCGACGCTTGAGGAGCTGGGCATCGGCTTCGTGCCTTTCAGCCCTCTCGGCAAGGGTTTCCTCACCGGCGCGATCA
ATGCGGACACGCAGTTCGCCAGCGACGATTTCCGCGCCAACGTCCCGCGCTTCTCGGAAGAGAACCGAAAGTCCAATCAG
GCGCTGGTCGACCTTCTTGGTCAGATCGCAGCCGAAATGGGCGTTACCTCTGCACAGATCGCGCTCGCCTGGCTCCTGTC
GCAAAAGCCATGGATCGTCCCGATCCCCGGCACCACCAGGCTTCATCGCCTGGAGGAGAATATCAGCGCCGCGAATGTGG
CGCTGACCGCTGACGATCTCTCCAGGATCGAGGCGGCCCTTTCAAACATCACGGTGCAGGGCGCGCGCTATAACGCCGCC
TATCAGGCCCTGGTCGGCCGGTAA

Upstream 100 bases:

>100_bases
GCGGTCGCAGCGATCGAGGTGCGCGGCCAGCGCCTGCCCGACGCCGTGCTGGCATTCTCGAACGTCGAGGCGCCTGAGAG
GAATTGAAGGGATTATCGCA

Downstream 100 bases:

>100_bases
TTCCATATACGAGGACGAATGAAATGACCGAGAACATCAAGGACAAGGTGGTCGTCATCACCGGCGCGTCGAGCGGGCTG
GGCGCGGAAACCGCCCGCCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MERRYLGDLEVSALGLGCMGLSHGYGPAVEKKDGIALIRAAVERGVTFFDTAEVYGPFTNEELVGEALEPVRDRVVIATK
FGFDIGGDNKERPLNSRPERIKKVADASLKRLRTDRIDLFYQHRVDPDVPIEDVAGAVRDLIAEGKVKHFGLSEAGVGTI
RRAHAVQPVAALQSEYSLWWREPEKDVLPTLEELGIGFVPFSPLGKGFLTGAINADTQFASDDFRANVPRFSEENRKSNQ
ALVDLLGQIAAEMGVTSAQIALAWLLSQKPWIVPIPGTTRLHRLEENISAANVALTADDLSRIEAALSNITVQGARYNAA
YQALVGR

Sequences:

>Translated_327_residues
MERRYLGDLEVSALGLGCMGLSHGYGPAVEKKDGIALIRAAVERGVTFFDTAEVYGPFTNEELVGEALEPVRDRVVIATK
FGFDIGGDNKERPLNSRPERIKKVADASLKRLRTDRIDLFYQHRVDPDVPIEDVAGAVRDLIAEGKVKHFGLSEAGVGTI
RRAHAVQPVAALQSEYSLWWREPEKDVLPTLEELGIGFVPFSPLGKGFLTGAINADTQFASDDFRANVPRFSEENRKSNQ
ALVDLLGQIAAEMGVTSAQIALAWLLSQKPWIVPIPGTTRLHRLEENISAANVALTADDLSRIEAALSNITVQGARYNAA
YQALVGR
>Mature_327_residues
MERRYLGDLEVSALGLGCMGLSHGYGPAVEKKDGIALIRAAVERGVTFFDTAEVYGPFTNEELVGEALEPVRDRVVIATK
FGFDIGGDNKERPLNSRPERIKKVADASLKRLRTDRIDLFYQHRVDPDVPIEDVAGAVRDLIAEGKVKHFGLSEAGVGTI
RRAHAVQPVAALQSEYSLWWREPEKDVLPTLEELGIGFVPFSPLGKGFLTGAINADTQFASDDFRANVPRFSEENRKSNQ
ALVDLLGQIAAEMGVTSAQIALAWLLSQKPWIVPIPGTTRLHRLEENISAANVALTADDLSRIEAALSNITVQGARYNAA
YQALVGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=331, Percent_Identity=29.9093655589124, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436964, Length=331, Percent_Identity=30.8157099697885, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI27436966, Length=331, Percent_Identity=30.2114803625378, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI27436962, Length=331, Percent_Identity=30.2114803625378, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=28.9634146341463, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI27436969, Length=331, Percent_Identity=30.2114803625378, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI223718702, Length=282, Percent_Identity=29.4326241134752, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=29.3286219081272, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=275, Percent_Identity=28.7272727272727, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87081735, Length=311, Percent_Identity=32.475884244373, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=31.0240963855422, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=31.7307692307692, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787674, Length=308, Percent_Identity=31.4935064935065, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=307, Percent_Identity=25.4071661237785, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=28.9940828402367, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994888, Length=281, Percent_Identity=28.8256227758007, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=317, Percent_Identity=27.1293375394322, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=25.1700680272109, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=27.190332326284, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=339, Percent_Identity=27.7286135693215, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=323, Percent_Identity=25.3869969040248, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=24.7191011235955, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640980, Length=339, Percent_Identity=24.7787610619469, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=24.7787610619469, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=309, Percent_Identity=25.5663430420712, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35747; Mature: 35747

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRYLGDLEVSALGLGCMGLSHGYGPAVEKKDGIALIRAAVERGVTFFDTAEVYGPFTN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEECHHHCCCCCC
EELVGEALEPVRDRVVIATKFGFDIGGDNKERPLNSRPERIKKVADASLKRLRTDRIDLF
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQHRVDPDVPIEDVAGAVRDLIAEGKVKHFGLSEAGVGTIRRAHAVQPVAALQSEYSLWW
EECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
REPEKDVLPTLEELGIGFVPFSPLGKGFLTGAINADTQFASDDFRANVPRFSEENRKSNQ
CCCCHHHHCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHCCCCCCCHHHHHHHH
ALVDLLGQIAAEMGVTSAQIALAWLLSQKPWIVPIPGTTRLHRLEENISAANVALTADDL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCHHEEEEEHHHH
SRIEAALSNITVQGARYNAAYQALVGR
HHHHHHHHHCEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MERRYLGDLEVSALGLGCMGLSHGYGPAVEKKDGIALIRAAVERGVTFFDTAEVYGPFTN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEECHHHCCCCCC
EELVGEALEPVRDRVVIATKFGFDIGGDNKERPLNSRPERIKKVADASLKRLRTDRIDLF
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQHRVDPDVPIEDVAGAVRDLIAEGKVKHFGLSEAGVGTIRRAHAVQPVAALQSEYSLWW
EECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
REPEKDVLPTLEELGIGFVPFSPLGKGFLTGAINADTQFASDDFRANVPRFSEENRKSNQ
CCCCHHHHCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHCCCCCCCHHHHHHHH
ALVDLLGQIAAEMGVTSAQIALAWLLSQKPWIVPIPGTTRLHRLEENISAANVALTADDL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCHHEEEEEHHHH
SRIEAALSNITVQGARYNAAYQALVGR
HHHHHHHHHCEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]