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The map label for this gene is iolC [H]

Identifier: 110636028

GI number: 110636028

Start: 3995925

End: 3997817

Strand: Reverse

Name: iolC [H]

Synonym: Meso_3703

Alternate gene names: 110636028

Gene position: 3997817-3995925 (Counterclockwise)

Preceding gene: 110636035

Following gene: 110636027

Centisome position: 90.6

GC content: 59.43

Gene sequence:

>1893_bases
GTGCAATTCGACGTTGCTGCATTAGGCCGGATCGCAGTCGATCTTTATGGCGAACAAAAGGGCACATCCCTGGAGGACAC
CGCGACATTCCGACGCTACGTCGGCGGCTCAAGCGGAAACTTGGCGATTGGCTGCGCAAGGCTCGGTCTGAAGACGGCGA
TGATTTCGAGTACCGGAGAAGACCCGATGGGACGGTATATCCGCGCCGAACTCGCCAAAGCAGGCGTTGATAATACCTGC
GTTACGGCAAATCCCCAGCGACGAACCGCCCTCGCGTTCCTTGGAATGCAGCGTGCCGATGCGATCGCGCTCGATTTCTA
CCGTGACCGCGCCGCGGACATGGCGGTTGGTTTCGGTGACCGTGAAGCGGAAAAGGTCCGCCAATCCAGATTACTGGCGC
TGACCGGCACGCACATGTCGGAACCGGGTACCGCCGACGCCCTGCGCAAAGCCGTCGAGACCGCCCGCGAGGCCGCAGGC
AAGGTCGTTCTGGACATCGACTTCCGCAAGGCCCTGTGGGAGCAGTCGCCGGGCGGCATTGAGGGTGTCGTCAGTTCAAT
CAATGATCTGCTGGACAAGATCAATATCGTCGTCGGCAACGAGGAGGAGTTCCTGAGGCTCGGTGGAAGCAACGATATTG
TCGAGGCTTTGAAGAAGGTCCGCGGCAACACGTCGGCTCTTCTCGTTTTGAAGCTCGGCGCCGAGGGCTCCATCGCGTTT
GCCGGTGAGATACCGCCTCGGTCCGAATGGAGACCTGTCCCGGGCTTCAAAGTCTACGTCCTAAATGTCGTCGGCGCGGG
CGACGCTTTCCTCGCGGGGTTCCTTTCGCTTTGGCTGCAAGGCGAGCCTGTCAACGCATGTTTGCGCAGAGGTAACCTGA
ATGGTGCGCTCGTTGTGTCGCGTCATGCATGCTCTGACGCCATGCCATTCCTGGCAGAGATCGAAACAATTGAAGATGAA
TCAGCGGTGGATCTGATAGCGAAGGGCAGCGAGCTGGAACGGCTGCATGCGGTGCTGAAACGGCCTCGTGTTGAAAGAGG
CCTCACCGCGCTTGCTTTCGACCATCGCGTCCCCTTCGCCCAGCTGATAGCCGAAACCGGGCGCTCTAAGGCTGACGCCA
TCGCTTTCAAGAAATTGATCGCCCGCGCCGCAAAGGAAGTTGCCGGAGAACGCGGTCTTGCCAATCCCGGCGTCCTGATC
GATCAGCATTACGGCACCGATGTGATGGAGGCCTTGACCGAAGACGGCTGGTGGGTCGGCCGCCCGGTGGAAGAAACGGG
CTCTCGTCCGCTGCGTTTTGAAGCCGAAGATTCGCTTGAGGAAACCATCTCCGCGTGGAACCCGAAGCACGTCGCCAAGG
TGCTGGTCTGGTATCATCCAGGCGATGACATCGCACTCAAGAACGAGCAACAGGCGAGCCTCAAAAGGCTGCAAGCCTGC
TGCCGCGGCCGTGGACAGGAGTGGATGCTGGAGGTCATTCTCCCGCTGGACCTTGAGCGGTCCGACGCGCTGCTCATTGC
TGCGGTCGGCGAGCTCTACGCTGCCGGCCTCAAGCCCGATTGGCTGAAGCTTTCCGGCTTCGAAACAGCAGACGCATGGG
ATCAGCTCGAGAGTATGGTCAAGAGCTTCGATCCCTACTGCCGTGGAGTTATTCTGCTGGGCCTCAGCCAGCCGATCGAA
GATTTGCGCATACCTATCGAGCTTGCCGCACAGCAGCCGTTCTGCCAAGGATTCGCTGTTGGACGGTCGATCTTCATGGA
CCCCGCAAGGAAATGGTTCGCCGGTATCTCGACGGACGAAGAAACCGTCAATGAGATCAAGGGGAACTACGCGAAGGTGG
TGGATATGTGGAGCTCTACAAAGCAAAGCACGTCGATAGCCGAGGTGGCTTGA

Upstream 100 bases:

>100_bases
AGACATTTTTTTCTATTGTTGCAAGATCAATTCGTTGACTGAATGAAAATAACATTCTAGCAAAAAACGAATGGACGCGC
ATGTTCGGAGGAGAGTTGTC

Downstream 100 bases:

>100_bases
TGGCCGCCGAAAACAAATCCATCGACGCGATTCTGGATCCGGTGATAGAGCCGCCGACATCGGCCGACGGCCTCATTAAT
CTCATCCGGCTTCGCCGCAT

Product: PfkB

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MQFDVAALGRIAVDLYGEQKGTSLEDTATFRRYVGGSSGNLAIGCARLGLKTAMISSTGEDPMGRYIRAELAKAGVDNTC
VTANPQRRTALAFLGMQRADAIALDFYRDRAADMAVGFGDREAEKVRQSRLLALTGTHMSEPGTADALRKAVETAREAAG
KVVLDIDFRKALWEQSPGGIEGVVSSINDLLDKINIVVGNEEEFLRLGGSNDIVEALKKVRGNTSALLVLKLGAEGSIAF
AGEIPPRSEWRPVPGFKVYVLNVVGAGDAFLAGFLSLWLQGEPVNACLRRGNLNGALVVSRHACSDAMPFLAEIETIEDE
SAVDLIAKGSELERLHAVLKRPRVERGLTALAFDHRVPFAQLIAETGRSKADAIAFKKLIARAAKEVAGERGLANPGVLI
DQHYGTDVMEALTEDGWWVGRPVEETGSRPLRFEAEDSLEETISAWNPKHVAKVLVWYHPGDDIALKNEQQASLKRLQAC
CRGRGQEWMLEVILPLDLERSDALLIAAVGELYAAGLKPDWLKLSGFETADAWDQLESMVKSFDPYCRGVILLGLSQPIE
DLRIPIELAAQQPFCQGFAVGRSIFMDPARKWFAGISTDEETVNEIKGNYAKVVDMWSSTKQSTSIAEVA

Sequences:

>Translated_630_residues
MQFDVAALGRIAVDLYGEQKGTSLEDTATFRRYVGGSSGNLAIGCARLGLKTAMISSTGEDPMGRYIRAELAKAGVDNTC
VTANPQRRTALAFLGMQRADAIALDFYRDRAADMAVGFGDREAEKVRQSRLLALTGTHMSEPGTADALRKAVETAREAAG
KVVLDIDFRKALWEQSPGGIEGVVSSINDLLDKINIVVGNEEEFLRLGGSNDIVEALKKVRGNTSALLVLKLGAEGSIAF
AGEIPPRSEWRPVPGFKVYVLNVVGAGDAFLAGFLSLWLQGEPVNACLRRGNLNGALVVSRHACSDAMPFLAEIETIEDE
SAVDLIAKGSELERLHAVLKRPRVERGLTALAFDHRVPFAQLIAETGRSKADAIAFKKLIARAAKEVAGERGLANPGVLI
DQHYGTDVMEALTEDGWWVGRPVEETGSRPLRFEAEDSLEETISAWNPKHVAKVLVWYHPGDDIALKNEQQASLKRLQAC
CRGRGQEWMLEVILPLDLERSDALLIAAVGELYAAGLKPDWLKLSGFETADAWDQLESMVKSFDPYCRGVILLGLSQPIE
DLRIPIELAAQQPFCQGFAVGRSIFMDPARKWFAGISTDEETVNEIKGNYAKVVDMWSSTKQSTSIAEVA
>Mature_630_residues
MQFDVAALGRIAVDLYGEQKGTSLEDTATFRRYVGGSSGNLAIGCARLGLKTAMISSTGEDPMGRYIRAELAKAGVDNTC
VTANPQRRTALAFLGMQRADAIALDFYRDRAADMAVGFGDREAEKVRQSRLLALTGTHMSEPGTADALRKAVETAREAAG
KVVLDIDFRKALWEQSPGGIEGVVSSINDLLDKINIVVGNEEEFLRLGGSNDIVEALKKVRGNTSALLVLKLGAEGSIAF
AGEIPPRSEWRPVPGFKVYVLNVVGAGDAFLAGFLSLWLQGEPVNACLRRGNLNGALVVSRHACSDAMPFLAEIETIEDE
SAVDLIAKGSELERLHAVLKRPRVERGLTALAFDHRVPFAQLIAETGRSKADAIAFKKLIARAAKEVAGERGLANPGVLI
DQHYGTDVMEALTEDGWWVGRPVEETGSRPLRFEAEDSLEETISAWNPKHVAKVLVWYHPGDDIALKNEQQASLKRLQAC
CRGRGQEWMLEVILPLDLERSDALLIAAVGELYAAGLKPDWLKLSGFETADAWDQLESMVKSFDPYCRGVILLGLSQPIE
DLRIPIELAAQQPFCQGFAVGRSIFMDPARKWFAGISTDEETVNEIKGNYAKVVDMWSSTKQSTSIAEVA

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17532905, Length=293, Percent_Identity=26.6211604095563, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 68527; Mature: 68527

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDVAALGRIAVDLYGEQKGTSLEDTATFRRYVGGSSGNLAIGCARLGLKTAMISSTGE
CCCCHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCC
DPMGRYIRAELAKAGVDNTCVTANPQRRTALAFLGMQRADAIALDFYRDRAADMAVGFGD
CHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCC
REAEKVRQSRLLALTGTHMSEPGTADALRKAVETAREAAGKVVLDIDFRKALWEQSPGGI
HHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCH
EGVVSSINDLLDKINIVVGNEEEFLRLGGSNDIVEALKKVRGNTSALLVLKLGAEGSIAF
HHHHHHHHHHHHHCEEEECCCHHHEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCCEEE
AGEIPPRSEWRPVPGFKVYVLNVVGAGDAFLAGFLSLWLQGEPVNACLRRGNLNGALVVS
ECCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEE
RHACSDAMPFLAEIETIEDESAVDLIAKGSELERLHAVLKRPRVERGLTALAFDHRVPFA
EHHCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCHH
QLIAETGRSKADAIAFKKLIARAAKEVAGERGLANPGVLIDQHYGTDVMEALTEDGWWVG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEC
RPVEETGSRPLRFEAEDSLEETISAWNPKHVAKVLVWYHPGDDIALKNEQQASLKRLQAC
CCHHHHCCCCEEECCHHHHHHHHHCCCHHHEEEEEEEEECCCCCEECCCHHHHHHHHHHH
CRGRGQEWMLEVILPLDLERSDALLIAAVGELYAAGLKPDWLKLSGFETADAWDQLESMV
HCCCCHHEEEHEEECCCCCCCCCEEEEEHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
KSFDPYCRGVILLGLSQPIEDLRIPIELAAQQPFCQGFAVGRSIFMDPARKWFAGISTDE
HHHCHHHHHEEEEECCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
ETVNEIKGNYAKVVDMWSSTKQSTSIAEVA
HHHHHHCCCHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure
MQFDVAALGRIAVDLYGEQKGTSLEDTATFRRYVGGSSGNLAIGCARLGLKTAMISSTGE
CCCCHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCC
DPMGRYIRAELAKAGVDNTCVTANPQRRTALAFLGMQRADAIALDFYRDRAADMAVGFGD
CHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCC
REAEKVRQSRLLALTGTHMSEPGTADALRKAVETAREAAGKVVLDIDFRKALWEQSPGGI
HHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCH
EGVVSSINDLLDKINIVVGNEEEFLRLGGSNDIVEALKKVRGNTSALLVLKLGAEGSIAF
HHHHHHHHHHHHHCEEEECCCHHHEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCCEEE
AGEIPPRSEWRPVPGFKVYVLNVVGAGDAFLAGFLSLWLQGEPVNACLRRGNLNGALVVS
ECCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEE
RHACSDAMPFLAEIETIEDESAVDLIAKGSELERLHAVLKRPRVERGLTALAFDHRVPFA
EHHCCCCCHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCHH
QLIAETGRSKADAIAFKKLIARAAKEVAGERGLANPGVLIDQHYGTDVMEALTEDGWWVG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEC
RPVEETGSRPLRFEAEDSLEETISAWNPKHVAKVLVWYHPGDDIALKNEQQASLKRLQAC
CCHHHHCCCCEEECCHHHHHHHHHCCCHHHEEEEEEEEECCCCCEECCCHHHHHHHHHHH
CRGRGQEWMLEVILPLDLERSDALLIAAVGELYAAGLKPDWLKLSGFETADAWDQLESMV
HCCCCHHEEEHEEECCCCCCCCCEEEEEHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
KSFDPYCRGVILLGLSQPIEDLRIPIELAAQQPFCQGFAVGRSIFMDPARKWFAGISTDE
HHHCHHHHHEEEEECCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
ETVNEIKGNYAKVVDMWSSTKQSTSIAEVA
HHHHHHCCCHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA