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The map label for this gene is malL [H]

Identifier: 110636012

GI number: 110636012

Start: 3975340

End: 3976962

Strand: Reverse

Name: malL [H]

Synonym: Meso_3687

Alternate gene names: 110636012

Gene position: 3976962-3975340 (Counterclockwise)

Preceding gene: 110636016

Following gene: 110636011

Centisome position: 90.13

GC content: 59.46

Gene sequence:

>1623_bases
ATGAAAGGCACAAGCCCTGACGTTGAGGTGCACTCATCGCAAGAGCCATGGTGGCGGCGCGGCGTCATCTACCAAATCTA
TCCGCGCTCCTTTCAGGACAGCAATGGCGACGGCATCGGCGACATCCGCGGCATCATAGATCGCCTGGACTACCTCGTCT
GGCTCGGGATAGATGCCGTCTGGATTTCGCCGATCTTCTTCTCGCCAATGGCCGATTTCGGCTATGACATCGCGGATTAT
CGCAAGATCGACCCTCTTTTCGGTACGCTCACGGATTTCGACCAGCTCATTGAAGCCGCGCATCGGCGTGGAATTCGGAT
ATTGCTCGACTATGTGCCGAACCACTCCTCAGACCGTCATCAATGGTTTCTGGAGGCGCGCAGCTCCCGCGATAATCCTC
GGCGCGATTTCTACATATGGCGGGATGCGGCGCCGGACGGGGGACCGCCAAACAACTGGCAAAGCGAATTCGGCGGCAGC
GCATGGGAACTGGATGCCGCAACCGGCCAATATTACTACCATGCCTTCCTGAAAGAGCAGCCCGATCTAAACTGGCGCAA
TCCAGAAGTGCGCCGTGAAATGTACGACGTGCTCCGCTTCTGGCTGGACCGGGGCGTCGACGGTTTTCGCGTCGATGTCA
TGTGGCATCTCATCAAGGACGCGGAGTTTCGCGACAATCCGCAGAACCCCGACTGGACCGAAGACATGCCGCCGCACAAG
TCGGTGCTTTCGATCTATTCCTGCGATCAGGAGGAGGTGCACGACGTAGTCTCCGAAATGCGCGCCGTGCTGGACGAATA
CGGGGGCGACCGGCTGCTTATCGGAGAAATATATCTGCCGATTGCCCGGCTCGTCGCCTATTATGGCCGGGATCTTCGCG
GTGCGCACCTGCCGTTCAATTTCCGCCTTATTGAGGCGCAATGGGACGCTCGCCACATCGAGCGGCAGATTGTCGAATAC
GAGGCCGCTCTGCCGGAGGGCGGCTGGCCGAACTGGGTTTTGAGCAATCACGATAAGCCGCGTATCGCCTCCCGTGTCGG
CCGGGACCAGGCGCGTGTTGCCGCCATGATGCTACTTACGTTGCGCGGCACGCCAACCATCTATTATGGCGACGAGATCG
GGATGAACGACGCTCCCATTCCGCCTGAGCGCGTGCAGGACCCGTTCGAGCTGCGCGTTCCCGGACGCGGTTTCGGGCGT
GATCCCCAACGCACGCCTATGCAGTGGGACAATACGGTGAATGCAGGCTTCAGCACCGGCTCGCCTTGGCTTCCTCTTGC
CCCGGACAAGGACAGCTTCAATGTGGAGGCGGAACGCAGCGATCCGCACTCAATGCTGTCGCTCTATCGCAGGCTGATTG
CATTCCGGCGAGAAAATGATGCGCTGAACCTTGGCCGTTACGCCTCCGTCGAGGCAGACAGCTGCGTGCTCGCTTACCTC
CGGGAGACGGAGAATGATCGCTATTTGATTGCACTTAATCTCGGGCCCGAGCCGGCGGTGCTGGAAACACCCGGGCAATG
CCGGATTGTGATCAGCACGGAAGGCAAGGCGGAAGGCGAGATTGTCGAGGAAAAGCTCCACCTGCAAGGCAATGAGGGCG
TGCTGGCGGAGATGATGAGTTAG

Upstream 100 bases:

>100_bases
CAGCAACCTTCGCCATTCGCCGATTTGCGCAGCGGAACATAAGCGACTTGCGTGTGTTCACCGCGTCATGGGGAACCCAG
GACCAGCGCGGAAGGAGCTC

Downstream 100 bases:

>100_bases
GCTGCGGTGACCAGCCCGATCTCGCCTTCGGTACGCCGCCGGAACGCTCCCTCGATCAAAAGCGTTGCCTGCTCGCATGA
GTATTTTCAATCGAGGATAT

Product: alpha amylase, catalytic region

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKGTSPDVEVHSSQEPWWRRGVIYQIYPRSFQDSNGDGIGDIRGIIDRLDYLVWLGIDAVWISPIFFSPMADFGYDIADY
RKIDPLFGTLTDFDQLIEAAHRRGIRILLDYVPNHSSDRHQWFLEARSSRDNPRRDFYIWRDAAPDGGPPNNWQSEFGGS
AWELDAATGQYYYHAFLKEQPDLNWRNPEVRREMYDVLRFWLDRGVDGFRVDVMWHLIKDAEFRDNPQNPDWTEDMPPHK
SVLSIYSCDQEEVHDVVSEMRAVLDEYGGDRLLIGEIYLPIARLVAYYGRDLRGAHLPFNFRLIEAQWDARHIERQIVEY
EAALPEGGWPNWVLSNHDKPRIASRVGRDQARVAAMMLLTLRGTPTIYYGDEIGMNDAPIPPERVQDPFELRVPGRGFGR
DPQRTPMQWDNTVNAGFSTGSPWLPLAPDKDSFNVEAERSDPHSMLSLYRRLIAFRRENDALNLGRYASVEADSCVLAYL
RETENDRYLIALNLGPEPAVLETPGQCRIVISTEGKAEGEIVEEKLHLQGNEGVLAEMMS

Sequences:

>Translated_540_residues
MKGTSPDVEVHSSQEPWWRRGVIYQIYPRSFQDSNGDGIGDIRGIIDRLDYLVWLGIDAVWISPIFFSPMADFGYDIADY
RKIDPLFGTLTDFDQLIEAAHRRGIRILLDYVPNHSSDRHQWFLEARSSRDNPRRDFYIWRDAAPDGGPPNNWQSEFGGS
AWELDAATGQYYYHAFLKEQPDLNWRNPEVRREMYDVLRFWLDRGVDGFRVDVMWHLIKDAEFRDNPQNPDWTEDMPPHK
SVLSIYSCDQEEVHDVVSEMRAVLDEYGGDRLLIGEIYLPIARLVAYYGRDLRGAHLPFNFRLIEAQWDARHIERQIVEY
EAALPEGGWPNWVLSNHDKPRIASRVGRDQARVAAMMLLTLRGTPTIYYGDEIGMNDAPIPPERVQDPFELRVPGRGFGR
DPQRTPMQWDNTVNAGFSTGSPWLPLAPDKDSFNVEAERSDPHSMLSLYRRLIAFRRENDALNLGRYASVEADSCVLAYL
RETENDRYLIALNLGPEPAVLETPGQCRIVISTEGKAEGEIVEEKLHLQGNEGVLAEMMS
>Mature_540_residues
MKGTSPDVEVHSSQEPWWRRGVIYQIYPRSFQDSNGDGIGDIRGIIDRLDYLVWLGIDAVWISPIFFSPMADFGYDIADY
RKIDPLFGTLTDFDQLIEAAHRRGIRILLDYVPNHSSDRHQWFLEARSSRDNPRRDFYIWRDAAPDGGPPNNWQSEFGGS
AWELDAATGQYYYHAFLKEQPDLNWRNPEVRREMYDVLRFWLDRGVDGFRVDVMWHLIKDAEFRDNPQNPDWTEDMPPHK
SVLSIYSCDQEEVHDVVSEMRAVLDEYGGDRLLIGEIYLPIARLVAYYGRDLRGAHLPFNFRLIEAQWDARHIERQIVEY
EAALPEGGWPNWVLSNHDKPRIASRVGRDQARVAAMMLLTLRGTPTIYYGDEIGMNDAPIPPERVQDPFELRVPGRGFGR
DPQRTPMQWDNTVNAGFSTGSPWLPLAPDKDSFNVEAERSDPHSMLSLYRRLIAFRRENDALNLGRYASVEADSCVLAYL
RETENDRYLIALNLGPEPAVLETPGQCRIVISTEGKAEGEIVEEKLHLQGNEGVLAEMMS

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=544, Percent_Identity=38.2352941176471, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI61744481, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI61744477, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI61744483, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI61744475, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI65506891, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI61744479, Length=537, Percent_Identity=24.2085661080074, Blast_Score=117, Evalue=4e-26,
Organism=Escherichia coli, GI1790687, Length=521, Percent_Identity=40.1151631477927, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1786604, Length=479, Percent_Identity=25.4697286012526, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081873, Length=295, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=39.5604395604396, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147709, Length=570, Percent_Identity=27.719298245614, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32565753, Length=506, Percent_Identity=25.6916996047431, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322245, Length=544, Percent_Identity=32.5367647058824, Blast_Score=282, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321726, Length=562, Percent_Identity=33.8078291814947, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6322241, Length=564, Percent_Identity=34.2198581560284, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322021, Length=564, Percent_Identity=34.2198581560284, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6324416, Length=560, Percent_Identity=33.2142857142857, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6319776, Length=553, Percent_Identity=32.368896925859, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6321731, Length=552, Percent_Identity=32.4275362318841, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24586593, Length=562, Percent_Identity=42.5266903914591, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24586591, Length=499, Percent_Identity=42.2845691382766, Blast_Score=387, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24583747, Length=501, Percent_Identity=42.7145708582834, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24583749, Length=501, Percent_Identity=42.7145708582834, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24586599, Length=509, Percent_Identity=41.6502946954813, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24583745, Length=563, Percent_Identity=37.6554174067496, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24586589, Length=497, Percent_Identity=42.0523138832998, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI221330053, Length=484, Percent_Identity=42.1487603305785, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI45549022, Length=544, Percent_Identity=39.1544117647059, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586597, Length=472, Percent_Identity=43.4322033898305, Blast_Score=360, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24586587, Length=522, Percent_Identity=40.0383141762452, Blast_Score=351, Evalue=9e-97,
Organism=Drosophila melanogaster, GI281360393, Length=503, Percent_Identity=40.5566600397614, Blast_Score=338, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 62164; Mature: 62164

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTSPDVEVHSSQEPWWRRGVIYQIYPRSFQDSNGDGIGDIRGIIDRLDYLVWLGIDAV
CCCCCCCCEEECCCCCHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
WISPIFFSPMADFGYDIADYRKIDPLFGTLTDFDQLIEAAHRRGIRILLDYVPNHSSDRH
HHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHH
QWFLEARSSRDNPRRDFYIWRDAAPDGGPPNNWQSEFGGSAWELDAATGQYYYHAFLKEQ
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEECCCCCCCEEEEEHHCC
PDLNWRNPEVRREMYDVLRFWLDRGVDGFRVDVMWHLIKDAEFRDNPQNPDWTEDMPPHK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
SVLSIYSCDQEEVHDVVSEMRAVLDEYGGDRLLIGEIYLPIARLVAYYGRDLRGAHLPFN
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEE
FRLIEAQWDARHIERQIVEYEAALPEGGWPNWVLSNHDKPRIASRVGRDQARVAAMMLLT
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHCHHHHHHHHHHHHH
LRGTPTIYYGDEIGMNDAPIPPERVQDPFELRVPGRGFGRDPQRTPMQWDNTVNAGFSTG
CCCCCEEEECCCCCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPWLPLAPDKDSFNVEAERSDPHSMLSLYRRLIAFRRENDALNLGRYASVEADSCVLAYL
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHH
RETENDRYLIALNLGPEPAVLETPGQCRIVISTEGKAEGEIVEEKLHLQGNEGVLAEMMS
HHCCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHCC
>Mature Secondary Structure
MKGTSPDVEVHSSQEPWWRRGVIYQIYPRSFQDSNGDGIGDIRGIIDRLDYLVWLGIDAV
CCCCCCCCEEECCCCCHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
WISPIFFSPMADFGYDIADYRKIDPLFGTLTDFDQLIEAAHRRGIRILLDYVPNHSSDRH
HHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHH
QWFLEARSSRDNPRRDFYIWRDAAPDGGPPNNWQSEFGGSAWELDAATGQYYYHAFLKEQ
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEECCCCCCCEEEEEHHCC
PDLNWRNPEVRREMYDVLRFWLDRGVDGFRVDVMWHLIKDAEFRDNPQNPDWTEDMPPHK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
SVLSIYSCDQEEVHDVVSEMRAVLDEYGGDRLLIGEIYLPIARLVAYYGRDLRGAHLPFN
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEE
FRLIEAQWDARHIERQIVEYEAALPEGGWPNWVLSNHDKPRIASRVGRDQARVAAMMLLT
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHCHHHHHHHHHHHHH
LRGTPTIYYGDEIGMNDAPIPPERVQDPFELRVPGRGFGRDPQRTPMQWDNTVNAGFSTG
CCCCCEEEECCCCCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPWLPLAPDKDSFNVEAERSDPHSMLSLYRRLIAFRRENDALNLGRYASVEADSCVLAYL
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHH
RETENDRYLIALNLGPEPAVLETPGQCRIVISTEGKAEGEIVEEKLHLQGNEGVLAEMMS
HHCCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8787404 [H]