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The map label for this gene is 110633089

Identifier: 110633089

GI number: 110633089

Start: 806461

End: 807387

Strand: Direct

Name: 110633089

Synonym: Meso_0732

Alternate gene names: NA

Gene position: 806461-807387 (Clockwise)

Preceding gene: 110633088

Following gene: 110633090

Centisome position: 18.28

GC content: 62.57

Gene sequence:

>927_bases
ATGCCAACTAGATTATACACCCACCCCATTTTTCTGGAGCACTTGGTGCCGCCCGGCCATCCGGAGCGGCCGGATCGGCT
GCGCGCGATTGAAAAAGTCCTCGCTCACGATGTCTTCAATCCGCTCGACCGCGTGTCGGCGCCCATGGCGGATTCGTCGG
CCGCCCTTCTCGCGCATATGGACGCTTATATCCGCCGCATGGAGCGTGAGATTCCGGCCGAGGGCATGGTCCGCATCGAT
GTGGACACGGTGGTGAGTCCGATTAGCTGGGATGCGGCGCTTACGGCCGTTGGCGGGGCCCTTGCTGCGGTCGATGACGT
CTTTACCGGCCGCGCGGACAACGCCTTCGTCGCCGCTCGCCCGCCTGGCCATCACGCGGAGAGGAACAGGGCGATGGGCT
TCTGCCTGTTCAACAATGCGGCGATTGCGGCCCGCCACGCTCAGAAGGCGCACGGAGCCGAGCGTGTCGCCATCGTGGAT
TGGGATGTGCACCATGGCAACGGCACTCAGGACATATTCTGGGACGATCCTTCGGTTCTTTATTGCTCCACGCATCAGAT
GCCGCTCTATCCCGGTACGGGAACTGAATCCGAAACGGGAGCAGGCAACATCGTCAACGTTCCGCTCGCACCGGGCGCGG
ACGGTGGGGATTTTCGGGAAGCGCTGGAGGCGGTGATCCTTCCCCGCATCAACGAATTTCAGCCGGACCTCATCATCATT
TCGGCGGGTTTCGATGCCCATTACCGCGATCCGCTGGCCCAGCTCAATTTCGACGAGCGGGATTTCGGCTGGGCAACCGC
CATGCTGATGGAGCGCGCCGGGCGCTGGTCGTCCAACCGGCTTGTCAGCCTGCTGGAAGGCGGCTACGACCTGGAAGGGC
TGGGCCTATCGGTAGCCGCTCATGTGGGACGCTTGATGAAAGGGTAA

Upstream 100 bases:

>100_bases
AACGGTGCGGCTCGTCAGTTGATGGACGTACGGCGCTGCAGGCTCTTGAGGGCGCTTTGCTCAGCGTGGCCAAGCGCCGC
TTAAGTACCTATATCGGGCT

Downstream 100 bases:

>100_bases
AGCATGACAACCGGAAACGACACCGCCGGGACGAATGACGACATCAAGGCCATGAGCTTCGAGCAGGCGCTGGAGGCACT
TGAAAGCATCGTGAACGACC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPTRLYTHPIFLEHLVPPGHPERPDRLRAIEKVLAHDVFNPLDRVSAPMADSSAALLAHMDAYIRRMEREIPAEGMVRID
VDTVVSPISWDAALTAVGGALAAVDDVFTGRADNAFVAARPPGHHAERNRAMGFCLFNNAAIAARHAQKAHGAERVAIVD
WDVHHGNGTQDIFWDDPSVLYCSTHQMPLYPGTGTESETGAGNIVNVPLAPGADGGDFREALEAVILPRINEFQPDLIII
SAGFDAHYRDPLAQLNFDERDFGWATAMLMERAGRWSSNRLVSLLEGGYDLEGLGLSVAAHVGRLMKG

Sequences:

>Translated_308_residues
MPTRLYTHPIFLEHLVPPGHPERPDRLRAIEKVLAHDVFNPLDRVSAPMADSSAALLAHMDAYIRRMEREIPAEGMVRID
VDTVVSPISWDAALTAVGGALAAVDDVFTGRADNAFVAARPPGHHAERNRAMGFCLFNNAAIAARHAQKAHGAERVAIVD
WDVHHGNGTQDIFWDDPSVLYCSTHQMPLYPGTGTESETGAGNIVNVPLAPGADGGDFREALEAVILPRINEFQPDLIII
SAGFDAHYRDPLAQLNFDERDFGWATAMLMERAGRWSSNRLVSLLEGGYDLEGLGLSVAAHVGRLMKG
>Mature_307_residues
PTRLYTHPIFLEHLVPPGHPERPDRLRAIEKVLAHDVFNPLDRVSAPMADSSAALLAHMDAYIRRMEREIPAEGMVRIDV
DTVVSPISWDAALTAVGGALAAVDDVFTGRADNAFVAARPPGHHAERNRAMGFCLFNNAAIAARHAQKAHGAERVAIVDW
DVHHGNGTQDIFWDDPSVLYCSTHQMPLYPGTGTESETGAGNIVNVPLAPGADGGDFREALEAVILPRINEFQPDLIIIS
AGFDAHYRDPLAQLNFDERDFGWATAMLMERAGRWSSNRLVSLLEGGYDLEGLGLSVAAHVGRLMKG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=304, Percent_Identity=39.1447368421053, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI20070354, Length=307, Percent_Identity=36.4820846905537, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI153085395, Length=281, Percent_Identity=39.5017793594306, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI169234807, Length=281, Percent_Identity=40.5693950177936, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI148539870, Length=281, Percent_Identity=40.5693950177936, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI62750349, Length=256, Percent_Identity=41.015625, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI62750347, Length=256, Percent_Identity=41.015625, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI17158039, Length=340, Percent_Identity=32.6470588235294, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI30795204, Length=340, Percent_Identity=32.6470588235294, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI30795202, Length=340, Percent_Identity=32.6470588235294, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI226529806, Length=307, Percent_Identity=33.2247557003257, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI13128860, Length=255, Percent_Identity=27.4509803921569, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI293336691, Length=253, Percent_Identity=26.8774703557312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI8923769, Length=283, Percent_Identity=24.7349823321555, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI13128862, Length=262, Percent_Identity=27.4809160305344, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI262073088, Length=174, Percent_Identity=29.3103448275862, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI262073092, Length=215, Percent_Identity=25.1162790697674, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI209862883, Length=279, Percent_Identity=24.0143369175627, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=311, Percent_Identity=37.2990353697749, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI193206283, Length=302, Percent_Identity=37.4172185430464, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17540332, Length=302, Percent_Identity=37.4172185430464, Blast_Score=180, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI193209491, Length=326, Percent_Identity=34.9693251533742, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25154020, Length=281, Percent_Identity=30.6049822064057, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25154022, Length=281, Percent_Identity=30.2491103202847, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17537347, Length=298, Percent_Identity=32.2147651006711, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508561, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534739, Length=252, Percent_Identity=26.5873015873016, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561978, Length=255, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324307, Length=331, Percent_Identity=34.7432024169184, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323999, Length=255, Percent_Identity=28.6274509803922, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325141, Length=284, Percent_Identity=27.112676056338, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=268, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=126, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642142, Length=306, Percent_Identity=36.6013071895425, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24642144, Length=306, Percent_Identity=36.6013071895425, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24642146, Length=306, Percent_Identity=36.6013071895425, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360899, Length=306, Percent_Identity=36.6013071895425, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24641720, Length=347, Percent_Identity=34.0057636887608, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360799, Length=347, Percent_Identity=34.0057636887608, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360801, Length=347, Percent_Identity=34.0057636887608, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24657891, Length=267, Percent_Identity=26.2172284644195, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644244, Length=274, Percent_Identity=25.1824817518248, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33551; Mature: 33420

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRLYTHPIFLEHLVPPGHPERPDRLRAIEKVLAHDVFNPLDRVSAPMADSSAALLAHM
CCCCEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHH
DAYIRRMEREIPAEGMVRIDVDTVVSPISWDAALTAVGGALAAVDDVFTGRADNAFVAAR
HHHHHHHHHHCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
PPGHHAERNRAMGFCLFNNAAIAARHAQKAHGAERVAIVDWDVHHGNGTQDIFWDDPSVL
CCCCCHHHCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCCEE
YCSTHQMPLYPGTGTESETGAGNIVNVPLAPGADGGDFREALEAVILPRINEFQPDLIII
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
SAGFDAHYRDPLAQLNFDERDFGWATAMLMERAGRWSSNRLVSLLEGGYDLEGLGLSVAA
ECCCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
HVGRLMKG
HHHHHHCC
>Mature Secondary Structure 
PTRLYTHPIFLEHLVPPGHPERPDRLRAIEKVLAHDVFNPLDRVSAPMADSSAALLAHM
CCCEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHH
DAYIRRMEREIPAEGMVRIDVDTVVSPISWDAALTAVGGALAAVDDVFTGRADNAFVAAR
HHHHHHHHHHCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
PPGHHAERNRAMGFCLFNNAAIAARHAQKAHGAERVAIVDWDVHHGNGTQDIFWDDPSVL
CCCCCHHHCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCCEE
YCSTHQMPLYPGTGTESETGAGNIVNVPLAPGADGGDFREALEAVILPRINEFQPDLIII
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
SAGFDAHYRDPLAQLNFDERDFGWATAMLMERAGRWSSNRLVSLLEGGYDLEGLGLSVAA
ECCCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
HVGRLMKG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]