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The map label for this gene is nccN [H]

Identifier: 110633029

GI number: 110633029

Start: 749264

End: 749884

Strand: Direct

Name: nccN [H]

Synonym: Meso_0672

Alternate gene names: 110633029

Gene position: 749264-749884 (Clockwise)

Preceding gene: 110633028

Following gene: 110633030

Centisome position: 16.98

GC content: 61.35

Gene sequence:

>621_bases
ATGAGCGGCGAGACCGCCAAGGCGATGGCTGCGTTCCAGTCCTCTCGCCGTTATGTGCTGGCTTTCCTGATCGGCATCAT
CTGCATTCTTCTCATCTTCGGCAGCTCGCTGCAGGGAGACTCGATGCATGAGCTGATCGAGGCCTACGGGCTCGCCCTCA
TCCTGATCGGGATTGGAGGGCGGCTCTGGTCGATCCTTTATATCGGCGGGCGGAAGTCCGCCGAACTCGTCTCCACCGGG
CCTTACTCGGTTACCCGCAATCCGCTTTATTTCTTTTCGACGATTGCGGCGGCGGGCGTGGGAGCGCAGACCGGCAGCAT
CGTCATCTCGCTTCTCGCTGGCCTCTTCTGTGCCGGCGCGTTCTATTTCGTGGCGCTCCGTGAGGAGCGCTATCTTCGAG
CCACGCTGGGCGCGCCCTATCTTGCTTATGTGCAGCGGGTGCCGCGTTTCGTCCCCAGCCCCTGGCTCTTCCGCGATCAG
GAGGAGGTCACCTTCCGGCCGCGGGTTTTCAACCGCACCCTGGTTGACGGTCTGGCCTTCTTCGCCTCCATCCCGTTTTT
CGAGCTGGTGGAGAAGGGGCGGGACCTGGGGATGATTCCGGTCCTCTTTCACTTTTATTGA

Upstream 100 bases:

>100_bases
GCTGGAGGGCCGTCAGATGATGATGGTGCTCGCCCCGAAATAGCCAAGATGCCGGTCGATCCGTTCCTTTGTCTGTGAAT
CGGCAGAGAGGGTTTCCTGA

Downstream 100 bases:

>100_bases
GGCGGGCGTCGCGCTATTGCGCGGGTGGCGACTTGCTGATATGAGGCGCCGTTCATTTGAGCCGTCCGGCAGGGCATGCC
GTGGCGGCTCGTAATGCTTC

Product: nickel-cobalt-cadmium resistance protein NCCN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSGETAKAMAAFQSSRRYVLAFLIGIICILLIFGSSLQGDSMHELIEAYGLALILIGIGGRLWSILYIGGRKSAELVSTG
PYSVTRNPLYFFSTIAAAGVGAQTGSIVISLLAGLFCAGAFYFVALREERYLRATLGAPYLAYVQRVPRFVPSPWLFRDQ
EEVTFRPRVFNRTLVDGLAFFASIPFFELVEKGRDLGMIPVLFHFY

Sequences:

>Translated_206_residues
MSGETAKAMAAFQSSRRYVLAFLIGIICILLIFGSSLQGDSMHELIEAYGLALILIGIGGRLWSILYIGGRKSAELVSTG
PYSVTRNPLYFFSTIAAAGVGAQTGSIVISLLAGLFCAGAFYFVALREERYLRATLGAPYLAYVQRVPRFVPSPWLFRDQ
EEVTFRPRVFNRTLVDGLAFFASIPFFELVEKGRDLGMIPVLFHFY
>Mature_205_residues
SGETAKAMAAFQSSRRYVLAFLIGIICILLIFGSSLQGDSMHELIEAYGLALILIGIGGRLWSILYIGGRKSAELVSTGP
YSVTRNPLYFFSTIAAAGVGAQTGSIVISLLAGLFCAGAFYFVALREERYLRATLGAPYLAYVQRVPRFVPSPWLFRDQE
EVTFRPRVFNRTLVDGLAFFASIPFFELVEKGRDLGMIPVLFHFY

Specific function: Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium. Appears to be involved in metal specificity but affects only nickel resistance. May be involved in nickel transport [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.eutrophus CzcN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 22788; Mature: 22657

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGETAKAMAAFQSSRRYVLAFLIGIICILLIFGSSLQGDSMHELIEAYGLALILIGIGG
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCH
RLWSILYIGGRKSAELVSTGPYSVTRNPLYFFSTIAAAGVGAQTGSIVISLLAGLFCAGA
HHHHEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FYFVALREERYLRATLGAPYLAYVQRVPRFVPSPWLFRDQEEVTFRPRVFNRTLVDGLAF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHH
FASIPFFELVEKGRDLGMIPVLFHFY
HHHCCHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SGETAKAMAAFQSSRRYVLAFLIGIICILLIFGSSLQGDSMHELIEAYGLALILIGIGG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCH
RLWSILYIGGRKSAELVSTGPYSVTRNPLYFFSTIAAAGVGAQTGSIVISLLAGLFCAGA
HHHHEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FYFVALREERYLRATLGAPYLAYVQRVPRFVPSPWLFRDQEEVTFRPRVFNRTLVDGLAF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHH
FASIPFFELVEKGRDLGMIPVLFHFY
HHHCCHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]