Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 110633028

GI number: 110633028

Start: 748628

End: 749206

Strand: Direct

Name: infC [H]

Synonym: Meso_0671

Alternate gene names: 110633028

Gene position: 748628-749206 (Clockwise)

Preceding gene: 110633017

Following gene: 110633029

Centisome position: 16.97

GC content: 58.38

Gene sequence:

>579_bases
TTGGGTAAGAGGCTTTTCGTCAACAACTGGGAGATAACGACCATTCGCAGACCATTCAAAGCCGCGCCTGTCGTAAAAGA
GGGCCCGCGCTCCAACCGGGATATCCGGGTCCCCCGGGTCCAACTTATCGATGACGACGGAAGCAATCGCGGCATTGTTT
CCACGGACGAGGCCTTGAGAATCGCCGAAGAGGCGGGGCTCGATCTCGTCGAGGTGTCGCCCAATGCCGATCCGCCCGTC
TGTAAGATCACTGATCTGGGCAAGCTCAAATACCAGAGCCAGAAAAAGGCCGCCGAGGCGCGCAAGAAGCAGAAGACCAT
CGAGATCAAGGAGATCAAGATGCGTCCGAACATCGACATCCATGATTATGAGGTGAAGATGCGTTCGGTGCGCCGCTTCT
TCGAGGAAGGCGACAAGGTGAAGTTGACTCTCCGGTTCCGCGGCCGTGAGATGGCTCACCTGGAGCTGGGCATGAAGCTG
CTCAACCGCGTGCGCGAGGACGTGGAGGGGATTGCCAAGGTCGAGGCCGAGCCAAAGCTGGAGGGCCGTCAGATGATGAT
GGTGCTCGCCCCGAAATAG

Upstream 100 bases:

>100_bases
TTGTTCCGAGGTCTGAAATTGCTCTTGCGGCGTGATTCTTCTGCCGGGTTATGCTATTGACAGTTCGCCCTGCAAGCCCA
CATAGCCGGCGGCCTGTTCT

Downstream 100 bases:

>100_bases
CCAAGATGCCGGTCGATCCGTTCCTTTGTCTGTGAATCGGCAGAGAGGGTTTCCTGAATGAGCGGCGAGACCGCCAAGGC
GATGGCTGCGTTCCAGTCCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MGKRLFVNNWEITTIRRPFKAAPVVKEGPRSNRDIRVPRVQLIDDDGSNRGIVSTDEALRIAEEAGLDLVEVSPNADPPV
CKITDLGKLKYQSQKKAAEARKKQKTIEIKEIKMRPNIDIHDYEVKMRSVRRFFEEGDKVKLTLRFRGREMAHLELGMKL
LNRVREDVEGIAKVEAEPKLEGRQMMMVLAPK

Sequences:

>Translated_192_residues
MGKRLFVNNWEITTIRRPFKAAPVVKEGPRSNRDIRVPRVQLIDDDGSNRGIVSTDEALRIAEEAGLDLVEVSPNADPPV
CKITDLGKLKYQSQKKAAEARKKQKTIEIKEIKMRPNIDIHDYEVKMRSVRRFFEEGDKVKLTLRFRGREMAHLELGMKL
LNRVREDVEGIAKVEAEPKLEGRQMMMVLAPK
>Mature_191_residues
GKRLFVNNWEITTIRRPFKAAPVVKEGPRSNRDIRVPRVQLIDDDGSNRGIVSTDEALRIAEEAGLDLVEVSPNADPPVC
KITDLGKLKYQSQKKAAEARKKQKTIEIKEIKMRPNIDIHDYEVKMRSVRRFFEEGDKVKLTLRFRGREMAHLELGMKLL
NRVREDVEGIAKVEAEPKLEGRQMMMVLAPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=59.7560975609756, Blast_Score=181, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22061; Mature: 21930

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRLFVNNWEITTIRRPFKAAPVVKEGPRSNRDIRVPRVQLIDDDGSNRGIVSTDEALR
CCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCEEECHHHHH
IAEEAGLDLVEVSPNADPPVCKITDLGKLKYQSQKKAAEARKKQKTIEIKEIKMRPNIDI
HHHHCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCE
HDYEVKMRSVRRFFEEGDKVKLTLRFRGREMAHLELGMKLLNRVREDVEGIAKVEAEPKL
EHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGRQMMMVLAPK
CCCEEEEEEECC
>Mature Secondary Structure 
GKRLFVNNWEITTIRRPFKAAPVVKEGPRSNRDIRVPRVQLIDDDGSNRGIVSTDEALR
CCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCEEECHHHHH
IAEEAGLDLVEVSPNADPPVCKITDLGKLKYQSQKKAAEARKKQKTIEIKEIKMRPNIDI
HHHHCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCE
HDYEVKMRSVRRFFEEGDKVKLTLRFRGREMAHLELGMKLLNRVREDVEGIAKVEAEPKL
EHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGRQMMMVLAPK
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA