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The map label for this gene is yciR [C]

Identifier: 110632952

GI number: 110632952

Start: 666990

End: 669182

Strand: Direct

Name: yciR [C]

Synonym: Meso_0595

Alternate gene names: 110632952

Gene position: 666990-669182 (Clockwise)

Preceding gene: 110632951

Following gene: 110632953

Centisome position: 15.12

GC content: 60.92

Gene sequence:

>2193_bases
ATGACCGACAAAAATCTCAATCTTGCAACGGAGATCCGAGTAGCCTTGGGCCTTATTGCTGCATTCGCCGCAGCGGGGGC
TATTGCCGTCTCGGTTGTCGCGTCTCTCAGGACCGATCAGGATGCAATTCTGAAACAGGAGCAGCTGACCCGGCACGCGC
TTGAGGAACAGATTGAGGCCGTGCCGCGGGACCAGCGCAGCGTTACCGTCTGGGATGAGGCCGTTGTTCATTCGCGCGAG
AACGATCAGCGTTGGATGGCGGAATATCTCGGCAAATGGATATACGACTATTTCGGCCATCAGCGCGCCTATGTTCTCGA
CGACCAAGGACATCTCATTTACGCCATGCTTGACGGCAAGACGGTCTCACCGCCGTCCTTCGGCAACGAAATCGCGGAGG
CTACGGAAATTGCCTCCAGCCTCCGGCGAAGGCTGATAGCACGGCGCTCTGCGGGCGATCAGGCCGAGCCGATCAAAAGC
GTTGTGGAAACGCGCGTGATCGACCTGAACGGCGCCCCAGCGATCCTGAGCATGCAGCCGATCATCCCGTCGACCAATCG
TTTGACCGTACCGGCGGGCGAGGAATATCTCTATGCTTCCGTCAATATGGTGGATAGCGCGCTCGCCGAGGAGATCGGTC
ACCATGTCCTACTCCAGGGCATGCGCTTCGATTCGTCTGCACCGAAGGGTTACCGTCAGGCGAGTGTTCCCGTGACCGGT
TCTACAGGCGAGGTTTTGGGCTATCTGATATGGGAGGCCGACAGGCCGGGGCTCCATCTGCTCAAGCAGGTGCTCCCGGC
TTGCCTTATTGCCCTTTTTGCTGTGGGCGGGATTGCGCTTTTCCTTGGCCGCAAGCTGCGCCGCGCTTCTCTCGCGCTTC
ATGCGAGCGAGCGCCGCGCCCGGCATCTCGCATCCCATGATGTTCTCACGCGCCTGCCGAACCGGGCCTTCTTCGAAAAG
AAGCTGGATAGGGTGATCGACACGGTTCAAGCCGGCCACGGCGAGGCGGCGCTGCTCTTCCTTGACCTGGATCGTTTCAA
AAACGTCAACGACACTCTTGGTCACCGGGCCGGCGATGAGCTGGTGCGGGAAACGGCTGTGAGGCTGAGCACGGCGATCG
GCAATGCCGGCGTCGTTGCACGCATAGGCGGCGACGAGTTCGGTATGGTGATCCTGCGGAGGAGTGGGGCCCGGGAAGCG
GCGATCGAGCTTTCTGAAAGACTGCTCCAGGCACTGAAGGTCCCCTTCGTCATCAGCGGCGAGCCCGTGCACGTTGGCGT
CAGCATCGGCGTAGCCCTTGCCCCTGAAGCGGGCAGCGAGCGTCAGGACCTCCTGCGCAAGGCCGACATCGCGCTTTATG
ACGCCAAGAAGCGCGGCCGCGGCTGTTACCAGATCTTCTCGGAGGCAATGGGCGATATTCTCAAGCAGCGCCGCCAGGTG
GAGGCTGACCTGCGCAACGCACTGGCAAACGGAGAGGAACTGCAGCTCTTCTACCAGCCGCTCTATTCCGATGCGAGCGA
GATTACCGGGGCTGAAGCGCTTCTGCGCTGGAAGCACCCGGTCCACGGCTCAATGTCGCCGGTGTTTCTGATCTCGGTGG
CTGAGGAATCCGGCATGATCATGCAGCTCGGCGATTGGGTCTTGCGGGAAGCCTGCAGAATGGCCGTCAAAGCCGATATC
CCCTTGATGTCGGTGAACGTGTCGGCGGTGCAGCTTCGCGATGAGCACTTCGCAGAGCGGTGCCTGGCGATCATCCGCCA
GGAGAACGTAGCGCCGGAACGGATTCAGCTCGAGGTCACAGAAACCGTGCTGATCGAAAATCCGGACCTTACCGTCAGGA
TCTTCGAAACGCTGCGTGAAGCGGGCATCCGCATCGCGATCGACGATTTCGGCACCGGCTACTCTTCGATGAGCTATCTC
CGCAACTATCCGGTCGACCGGCTCAAGATTGACCGTTCGTTCGTGCAGGCTCTTTCGGAAAGCAAGCAGGGACGTGCAAT
CGTTGGAGCCATGCTCGACATTGCGCGGGCGCTGGAGCTGGACGTGGTCGCCGAGGGCGTGGAGACAGTGGACCAGTGCA
AGGTTCTGCGCTCACTCGGCTGCCGCGAGATGCAAGGCTATCTCTTCTCGCGCCCCCTCGAGCCGCTGCAGTTCCTGCAC
TCCCTGAAGCGTCCCGTTCCCTTGACCGCCTAG

Upstream 100 bases:

>100_bases
GGCCTAGGCCATTCAGCCTGATGGTCAAAGAGTAGAAAGAAGATCATATGCGGCGGTAGGAGCGGATCAGCCCGTTCATG
TCCGAGCTATTAGGGCCAGT

Downstream 100 bases:

>100_bases
AAAGCTATTCGCGGGCGTCGGGAAGTAACGTTTTGGAAAGGTTGAAGCAGGTCCAGTGCTGAAATATGGGAACTACGCCC
GTTACTAGTGCTTTTTCTGA

Product: periplasmic sensor diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MTDKNLNLATEIRVALGLIAAFAAAGAIAVSVVASLRTDQDAILKQEQLTRHALEEQIEAVPRDQRSVTVWDEAVVHSRE
NDQRWMAEYLGKWIYDYFGHQRAYVLDDQGHLIYAMLDGKTVSPPSFGNEIAEATEIASSLRRRLIARRSAGDQAEPIKS
VVETRVIDLNGAPAILSMQPIIPSTNRLTVPAGEEYLYASVNMVDSALAEEIGHHVLLQGMRFDSSAPKGYRQASVPVTG
STGEVLGYLIWEADRPGLHLLKQVLPACLIALFAVGGIALFLGRKLRRASLALHASERRARHLASHDVLTRLPNRAFFEK
KLDRVIDTVQAGHGEAALLFLDLDRFKNVNDTLGHRAGDELVRETAVRLSTAIGNAGVVARIGGDEFGMVILRRSGAREA
AIELSERLLQALKVPFVISGEPVHVGVSIGVALAPEAGSERQDLLRKADIALYDAKKRGRGCYQIFSEAMGDILKQRRQV
EADLRNALANGEELQLFYQPLYSDASEITGAEALLRWKHPVHGSMSPVFLISVAEESGMIMQLGDWVLREACRMAVKADI
PLMSVNVSAVQLRDEHFAERCLAIIRQENVAPERIQLEVTETVLIENPDLTVRIFETLREAGIRIAIDDFGTGYSSMSYL
RNYPVDRLKIDRSFVQALSESKQGRAIVGAMLDIARALELDVVAEGVETVDQCKVLRSLGCREMQGYLFSRPLEPLQFLH
SLKRPVPLTA

Sequences:

>Translated_730_residues
MTDKNLNLATEIRVALGLIAAFAAAGAIAVSVVASLRTDQDAILKQEQLTRHALEEQIEAVPRDQRSVTVWDEAVVHSRE
NDQRWMAEYLGKWIYDYFGHQRAYVLDDQGHLIYAMLDGKTVSPPSFGNEIAEATEIASSLRRRLIARRSAGDQAEPIKS
VVETRVIDLNGAPAILSMQPIIPSTNRLTVPAGEEYLYASVNMVDSALAEEIGHHVLLQGMRFDSSAPKGYRQASVPVTG
STGEVLGYLIWEADRPGLHLLKQVLPACLIALFAVGGIALFLGRKLRRASLALHASERRARHLASHDVLTRLPNRAFFEK
KLDRVIDTVQAGHGEAALLFLDLDRFKNVNDTLGHRAGDELVRETAVRLSTAIGNAGVVARIGGDEFGMVILRRSGAREA
AIELSERLLQALKVPFVISGEPVHVGVSIGVALAPEAGSERQDLLRKADIALYDAKKRGRGCYQIFSEAMGDILKQRRQV
EADLRNALANGEELQLFYQPLYSDASEITGAEALLRWKHPVHGSMSPVFLISVAEESGMIMQLGDWVLREACRMAVKADI
PLMSVNVSAVQLRDEHFAERCLAIIRQENVAPERIQLEVTETVLIENPDLTVRIFETLREAGIRIAIDDFGTGYSSMSYL
RNYPVDRLKIDRSFVQALSESKQGRAIVGAMLDIARALELDVVAEGVETVDQCKVLRSLGCREMQGYLFSRPLEPLQFLH
SLKRPVPLTA
>Mature_729_residues
TDKNLNLATEIRVALGLIAAFAAAGAIAVSVVASLRTDQDAILKQEQLTRHALEEQIEAVPRDQRSVTVWDEAVVHSREN
DQRWMAEYLGKWIYDYFGHQRAYVLDDQGHLIYAMLDGKTVSPPSFGNEIAEATEIASSLRRRLIARRSAGDQAEPIKSV
VETRVIDLNGAPAILSMQPIIPSTNRLTVPAGEEYLYASVNMVDSALAEEIGHHVLLQGMRFDSSAPKGYRQASVPVTGS
TGEVLGYLIWEADRPGLHLLKQVLPACLIALFAVGGIALFLGRKLRRASLALHASERRARHLASHDVLTRLPNRAFFEKK
LDRVIDTVQAGHGEAALLFLDLDRFKNVNDTLGHRAGDELVRETAVRLSTAIGNAGVVARIGGDEFGMVILRRSGAREAA
IELSERLLQALKVPFVISGEPVHVGVSIGVALAPEAGSERQDLLRKADIALYDAKKRGRGCYQIFSEAMGDILKQRRQVE
ADLRNALANGEELQLFYQPLYSDASEITGAEALLRWKHPVHGSMSPVFLISVAEESGMIMQLGDWVLREACRMAVKADIP
LMSVNVSAVQLRDEHFAERCLAIIRQENVAPERIQLEVTETVLIENPDLTVRIFETLREAGIRIAIDDFGTGYSSMSYLR
NYPVDRLKIDRSFVQALSESKQGRAIVGAMLDIARALELDVVAEGVETVDQCKVLRSLGCREMQGYLFSRPLEPLQFLHS
LKRPVPLTA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=36.2586605080831, Blast_Score=281, Evalue=1e-76,
Organism=Escherichia coli, GI87081921, Length=433, Percent_Identity=33.0254041570439, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=30.2663438256659, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=36.8200836820084, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788502, Length=273, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=36.5145228215768, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=35.9832635983264, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1786507, Length=239, Percent_Identity=35.1464435146443, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081743, Length=260, Percent_Identity=34.6153846153846, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788381, Length=170, Percent_Identity=40, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI87081980, Length=227, Percent_Identity=35.2422907488987, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=33.195020746888, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788849, Length=256, Percent_Identity=30.859375, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=32.4175824175824, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI145693134, Length=177, Percent_Identity=31.0734463276836, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787262, Length=178, Percent_Identity=30.3370786516854, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=36.094674556213, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=198, Percent_Identity=30.8080808080808, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=196, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=31.7880794701987, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=34.7058823529412, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=156, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787802, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=34.3949044585987, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 80593; Mature: 80461

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKNLNLATEIRVALGLIAAFAAAGAIAVSVVASLRTDQDAILKQEQLTRHALEEQIEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VPRDQRSVTVWDEAVVHSRENDQRWMAEYLGKWIYDYFGHQRAYVLDDQGHLIYAMLDGK
CCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCC
TVSPPSFGNEIAEATEIASSLRRRLIARRSAGDQAEPIKSVVETRVIDLNGAPAILSMQP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCEEEECC
IIPSTNRLTVPAGEEYLYASVNMVDSALAEEIGHHVLLQGMRFDSSAPKGYRQASVPVTG
CCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCC
STGEVLGYLIWEADRPGLHLLKQVLPACLIALFAVGGIALFLGRKLRRASLALHASERRA
CCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLASHDVLTRLPNRAFFEKKLDRVIDTVQAGHGEAALLFLDLDRFKNVNDTLGHRAGDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCHHHCCCHHHH
LVRETAVRLSTAIGNAGVVARIGGDEFGMVILRRSGAREAAIELSERLLQALKVPFVISG
HHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEECC
EPVHVGVSIGVALAPEAGSERQDLLRKADIALYDAKKRGRGCYQIFSEAMGDILKQRRQV
CCEEEEEEEEEEECCCCCCHHHHHHHHHHHHEEECHHHCCHHHHHHHHHHHHHHHHHHHH
EADLRNALANGEELQLFYQPLYSDASEITGAEALLRWKHPVHGSMSPVFLISVAEESGMI
HHHHHHHHCCCHHHHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCE
MQLGDWVLREACRMAVKADIPLMSVNVSAVQLRDEHFAERCLAIIRQENVAPERIQLEVT
EHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
ETVLIENPDLTVRIFETLREAGIRIAIDDFGTGYSSMSYLRNYPVDRLKIDRSFVQALSE
EEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
SKQGRAIVGAMLDIARALELDVVAEGVETVDQCKVLRSLGCREMQGYLFSRPLEPLQFLH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
SLKRPVPLTA
HHCCCCCCCC
>Mature Secondary Structure 
TDKNLNLATEIRVALGLIAAFAAAGAIAVSVVASLRTDQDAILKQEQLTRHALEEQIEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VPRDQRSVTVWDEAVVHSRENDQRWMAEYLGKWIYDYFGHQRAYVLDDQGHLIYAMLDGK
CCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCC
TVSPPSFGNEIAEATEIASSLRRRLIARRSAGDQAEPIKSVVETRVIDLNGAPAILSMQP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCEEEECC
IIPSTNRLTVPAGEEYLYASVNMVDSALAEEIGHHVLLQGMRFDSSAPKGYRQASVPVTG
CCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCC
STGEVLGYLIWEADRPGLHLLKQVLPACLIALFAVGGIALFLGRKLRRASLALHASERRA
CCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLASHDVLTRLPNRAFFEKKLDRVIDTVQAGHGEAALLFLDLDRFKNVNDTLGHRAGDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCHHHCCCHHHH
LVRETAVRLSTAIGNAGVVARIGGDEFGMVILRRSGAREAAIELSERLLQALKVPFVISG
HHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEECC
EPVHVGVSIGVALAPEAGSERQDLLRKADIALYDAKKRGRGCYQIFSEAMGDILKQRRQV
CCEEEEEEEEEEECCCCCCHHHHHHHHHHHHEEECHHHCCHHHHHHHHHHHHHHHHHHHH
EADLRNALANGEELQLFYQPLYSDASEITGAEALLRWKHPVHGSMSPVFLISVAEESGMI
HHHHHHHHCCCHHHHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCE
MQLGDWVLREACRMAVKADIPLMSVNVSAVQLRDEHFAERCLAIIRQENVAPERIQLEVT
EHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
ETVLIENPDLTVRIFETLREAGIRIAIDDFGTGYSSMSYLRNYPVDRLKIDRSFVQALSE
EEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
SKQGRAIVGAMLDIARALELDVVAEGVETVDQCKVLRSLGCREMQGYLFSRPLEPLQFLH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
SLKRPVPLTA
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]