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The map label for this gene is echA12 [H]

Identifier: 110632842

GI number: 110632842

Start: 530816

End: 531580

Strand: Direct

Name: echA12 [H]

Synonym: Meso_0481

Alternate gene names: 110632842

Gene position: 530816-531580 (Clockwise)

Preceding gene: 110632841

Following gene: 110632843

Centisome position: 12.03

GC content: 56.86

Gene sequence:

>765_bases
ATGAGCACTTTTGCCGATTACGCCGAAAAATACTCCATGATTAAGATGCGTCGCGAGGATGGTATCCTTGAGATGCGCTT
CCACACGGACGGAGGTCCTTTTCAGTGGAGCCTTATTCCACACGCCGAGCTTGAACAAGCTTTCCTCGATGTGGGCCGTG
ATTACGACAACGAGGTTGTAATCCTTACGGGCACCGGCGACGAATATTGCGGCCCGCTGGTCAAGGAGGGGGGCCATCCT
AACCGAGCTAATGCCACCCCAAACCGCTACGACCGCATCTACTGGGAAGCGAAGCACCTCCTCAACAACCTGCTCAACAT
TGAGGTGCCAGTGATCAGCGCGATCAACGGCCCGGCTGTCCGGCATGCCGAAATCCCGCTCTTGAGCGACATCGTTCTGG
CTAGTGATACAACTTATTTCATGGATTCGGCACACTACCAGGGTGGAATGGTGCCTGGGGACGGCGTGCACATCATTTTC
CCGCTGCTGATGGGCGCCAACCGTGCGCGATATTACCTTCTGACAGGTCAGAAAATCCCAGCAGACGAGGCGAAGGCAGT
GGGCCTTGTGAACGAGGTCCTACCCGCCAACGAGGTATTGCCACGCGCATGGGAGCTTGCCCGCCAACTCATGAAGCAGC
CGCGTCTCGTACGCCGATACAGCCGGGTTGTGCTGACCCAGGACCTAAAGGAACGCATGCAGGGACTGCTCGGCTACGGC
CTGGCTCTTGAGGGCCTAGCACGCATCAAAATGGACGAAAAGTGA

Upstream 100 bases:

>100_bases
TCGGCTTCGACGTGGCCTGTTTCCCAGTGAAAATCACCGGCGGCTCCGCGGGGTGGACGCGCGCAGTCGCCATTATCGAC
GAACCCGGGGATTGAGACAC

Downstream 100 bases:

>100_bases
CCGTCTCGACCATTTCTAGAGGAGGAAGACGATGGTAGCAGCGGCAGATTTTGACGAAGTGGTGGACGTCGTAGCCATAG
GCTACGGCTTCGCCGGTGCA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSTFADYAEKYSMIKMRREDGILEMRFHTDGGPFQWSLIPHAELEQAFLDVGRDYDNEVVILTGTGDEYCGPLVKEGGHP
NRANATPNRYDRIYWEAKHLLNNLLNIEVPVISAINGPAVRHAEIPLLSDIVLASDTTYFMDSAHYQGGMVPGDGVHIIF
PLLMGANRARYYLLTGQKIPADEAKAVGLVNEVLPANEVLPRAWELARQLMKQPRLVRRYSRVVLTQDLKERMQGLLGYG
LALEGLARIKMDEK

Sequences:

>Translated_254_residues
MSTFADYAEKYSMIKMRREDGILEMRFHTDGGPFQWSLIPHAELEQAFLDVGRDYDNEVVILTGTGDEYCGPLVKEGGHP
NRANATPNRYDRIYWEAKHLLNNLLNIEVPVISAINGPAVRHAEIPLLSDIVLASDTTYFMDSAHYQGGMVPGDGVHIIF
PLLMGANRARYYLLTGQKIPADEAKAVGLVNEVLPANEVLPRAWELARQLMKQPRLVRRYSRVVLTQDLKERMQGLLGYG
LALEGLARIKMDEK
>Mature_253_residues
STFADYAEKYSMIKMRREDGILEMRFHTDGGPFQWSLIPHAELEQAFLDVGRDYDNEVVILTGTGDEYCGPLVKEGGHPN
RANATPNRYDRIYWEAKHLLNNLLNIEVPVISAINGPAVRHAEIPLLSDIVLASDTTYFMDSAHYQGGMVPGDGVHIIFP
LLMGANRARYYLLTGQKIPADEAKAVGLVNEVLPANEVLPRAWELARQLMKQPRLVRRYSRVVLTQDLKERMQGLLGYGL
ALEGLARIKMDEK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI221136756, Length=213, Percent_Identity=28.169014084507, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI221136753, Length=213, Percent_Identity=28.169014084507, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI221307494, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535521, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=205, Percent_Identity=30.2439024390244, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654903, Length=206, Percent_Identity=23.7864077669903, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28609; Mature: 28478

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFADYAEKYSMIKMRREDGILEMRFHTDGGPFQWSLIPHAELEQAFLDVGRDYDNEVV
CCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCEE
ILTGTGDEYCGPLVKEGGHPNRANATPNRYDRIYWEAKHLLNNLLNIEVPVISAINGPAV
EEECCCCHHHCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCE
RHAEIPLLSDIVLASDTTYFMDSAHYQGGMVPGDGVHIIFPLLMGANRARYYLLTGQKIP
EECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
ADEAKAVGLVNEVLPANEVLPRAWELARQLMKQPRLVRRYSRVVLTQDLKERMQGLLGYG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALEGLARIKMDEK
HHHHHHHHHCCCCC
>Mature Secondary Structure 
STFADYAEKYSMIKMRREDGILEMRFHTDGGPFQWSLIPHAELEQAFLDVGRDYDNEVV
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCEE
ILTGTGDEYCGPLVKEGGHPNRANATPNRYDRIYWEAKHLLNNLLNIEVPVISAINGPAV
EEECCCCHHHCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCE
RHAEIPLLSDIVLASDTTYFMDSAHYQGGMVPGDGVHIIFPLLMGANRARYYLLTGQKIP
EECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
ADEAKAVGLVNEVLPANEVLPRAWELARQLMKQPRLVRRYSRVVLTQDLKERMQGLLGYG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALEGLARIKMDEK
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]