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The map label for this gene is gsiC [H]

Identifier: 110632821

GI number: 110632821

Start: 508087

End: 509001

Strand: Direct

Name: gsiC [H]

Synonym: Meso_0460

Alternate gene names: 110632821

Gene position: 508087-509001 (Clockwise)

Preceding gene: 110632820

Following gene: 110632822

Centisome position: 11.51

GC content: 63.06

Gene sequence:

>915_bases
GTGGCGAGCATCGTTCTTTTCGTTCTGCTGCGTCTCCTTCCGGGAGATCCCGCCAACGCGCTCGTTTCGGTAGGCGCCGA
TCCGGCGCAGATCGAGGCAGCGCGCCGCCAGGTCGGCTCCGACCTGCCGCTCGCGCAACAGTTCCTGCAGTTTCTCACCA
GCCTGGCCCGGCTCGACCTTGGCACGTCCTTCGTCAGCCGCACGTCCGTGCTTCAGGAGATCCTGGCCCGCCTGGCGGTC
ACCGTGCCGCTGACTTTGCTTTCCTTCATGCTTGCCGTGCTGATCGCGGTGCCGCTCGGTATACTGTCCGCGGTCAAGGC
GGAGCGCTGGTTTGGCGCCCTGATATCCGTGATCTCGCAGCTCGGCATCGCCATTCCCGTTTTTTGGGTCGGCATTCTCC
TCGTGACGCTTTTTGCGGTGAACCTGCGGCTCTTTCCTTCCGGCGGCTTTCCCCCGCAGGGCTGGGCCGCCCCCTTTGAG
GCGCTTCGGGCGCTGTTTCTCCCAATCGTGACGATTGCCGTCGTCATGTCCGCTTCGCTGTTGCGCTATGTCCGCTCGGC
TACGCAGGACGTGCTGGGCAGCGACTATCTGCGCACGGCGCGGGCACTTGGTTCGGGCTTTGCGGAAGCGCTCATTCGAC
ATGGCATCCGCAATGGCGCGGTGCCGGTAGTTTCTATCCTCGGCATCGAGCTTGCGACGACGCTTCTGGGAGCGGTGGTG
GTGGAGCGCGTATTCACGCTGCCGGGCTTGGGCTCCATGCTGCTTCTCGCAATCGAGCAGCGTGATTATCCCAACATCCA
GGGCGTGCTCTTCATTTCCACGTTGCTCGTGCTGCTTATCGGATTCTTCGCCGATCTTGCCCAGCGCTGGATCGATCCGC
GCCTGCGCGAAAAGCTGGGGAATATACGTCGATGA

Upstream 100 bases:

>100_bases
ACCAAGCGCGCGCAGTAGTCGTTCAGGCGAGCCGCGGAAGGAGGGGCCAATCCTCGCTTACATTATCCGTCGGCTCGCCA
TCCTCCTTTTCTCGCTCCTT

Downstream 100 bases:

>100_bases
CCGTCCTTGCCGAGCCGCAGGCGGAGCGCACCCGCCGCACCCGCCGGTCACTTACGTTCAGCATCGGCCTGATTTTGGTC
GGCTTGCATTTGGCAGTGGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MASIVLFVLLRLLPGDPANALVSVGADPAQIEAARRQVGSDLPLAQQFLQFLTSLARLDLGTSFVSRTSVLQEILARLAV
TVPLTLLSFMLAVLIAVPLGILSAVKAERWFGALISVISQLGIAIPVFWVGILLVTLFAVNLRLFPSGGFPPQGWAAPFE
ALRALFLPIVTIAVVMSASLLRYVRSATQDVLGSDYLRTARALGSGFAEALIRHGIRNGAVPVVSILGIELATTLLGAVV
VERVFTLPGLGSMLLLAIEQRDYPNIQGVLFISTLLVLLIGFFADLAQRWIDPRLREKLGNIRR

Sequences:

>Translated_304_residues
MASIVLFVLLRLLPGDPANALVSVGADPAQIEAARRQVGSDLPLAQQFLQFLTSLARLDLGTSFVSRTSVLQEILARLAV
TVPLTLLSFMLAVLIAVPLGILSAVKAERWFGALISVISQLGIAIPVFWVGILLVTLFAVNLRLFPSGGFPPQGWAAPFE
ALRALFLPIVTIAVVMSASLLRYVRSATQDVLGSDYLRTARALGSGFAEALIRHGIRNGAVPVVSILGIELATTLLGAVV
VERVFTLPGLGSMLLLAIEQRDYPNIQGVLFISTLLVLLIGFFADLAQRWIDPRLREKLGNIRR
>Mature_303_residues
ASIVLFVLLRLLPGDPANALVSVGADPAQIEAARRQVGSDLPLAQQFLQFLTSLARLDLGTSFVSRTSVLQEILARLAVT
VPLTLLSFMLAVLIAVPLGILSAVKAERWFGALISVISQLGIAIPVFWVGILLVTLFAVNLRLFPSGGFPPQGWAAPFEA
LRALFLPIVTIAVVMSASLLRYVRSATQDVLGSDYLRTARALGSGFAEALIRHGIRNGAVPVVSILGIELATTLLGAVVV
ERVFTLPGLGSMLLLAIEQRDYPNIQGVLFISTLLVLLIGFFADLAQRWIDPRLREKLGNIRR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=296, Percent_Identity=36.4864864864865, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1789965, Length=319, Percent_Identity=30.4075235109718, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787761, Length=320, Percent_Identity=34.0625, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789888, Length=302, Percent_Identity=32.1192052980132, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787497, Length=292, Percent_Identity=29.4520547945205, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=28.158844765343, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788504, Length=280, Percent_Identity=30.7142857142857, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32725; Mature: 32593

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIVLFVLLRLLPGDPANALVSVGADPAQIEAARRQVGSDLPLAQQFLQFLTSLARLDL
CHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GTSFVSRTSVLQEILARLAVTVPLTLLSFMLAVLIAVPLGILSAVKAERWFGALISVISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIAIPVFWVGILLVTLFAVNLRLFPSGGFPPQGWAAPFEALRALFLPIVTIAVVMSASL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRYVRSATQDVLGSDYLRTARALGSGFAEALIRHGIRNGAVPVVSILGIELATTLLGAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VERVFTLPGLGSMLLLAIEQRDYPNIQGVLFISTLLVLLIGFFADLAQRWIDPRLREKLG
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NIRR
CCCC
>Mature Secondary Structure 
ASIVLFVLLRLLPGDPANALVSVGADPAQIEAARRQVGSDLPLAQQFLQFLTSLARLDL
HHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GTSFVSRTSVLQEILARLAVTVPLTLLSFMLAVLIAVPLGILSAVKAERWFGALISVISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIAIPVFWVGILLVTLFAVNLRLFPSGGFPPQGWAAPFEALRALFLPIVTIAVVMSASL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRYVRSATQDVLGSDYLRTARALGSGFAEALIRHGIRNGAVPVVSILGIELATTLLGAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VERVFTLPGLGSMLLLAIEQRDYPNIQGVLFISTLLVLLIGFFADLAQRWIDPRLREKLG
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NIRR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]