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The map label for this gene is sseA [H]

Identifier: 110632766

GI number: 110632766

Start: 448667

End: 449521

Strand: Direct

Name: sseA [H]

Synonym: Meso_0405

Alternate gene names: 110632766

Gene position: 448667-449521 (Clockwise)

Preceding gene: 110632765

Following gene: 110632767

Centisome position: 10.17

GC content: 62.46

Gene sequence:

>855_bases
TTGCAGCGGCAGCAGAACGGTTCACTTGTCACAACGGAATGGCTTGCCGCTCATCTCGACGATCCCGATCTGGTCCTGCT
TGACGCATCCTTCAAGCTTCCCGGCGTGGCGCCCACGGCTGAGGAGGATTTTTCCGAACGCCACATTCCCGGCGCCCAAT
TTTTCGATGTTGATGCGATCGCCGATCACAAGAACCCGCTCCCGCACATGCTTCCGCCTCCGGAGGTCTTTGCCGAGCAC
TCCTCCGCCTTCGGCATCTCGAATGGACACACGGTGATCATCTACGACACGCCGGGGCTGATGTCGGCAGGCCGCGCCTG
GTGGATGTTCCGCACCTTCGGCCATGTGAATGTCGCCATTCTGGATGGCGGGCTCAAAAAATGGCTGGCGGAGGGCCGGC
CCGTCACTCACGAAGTGAGGTCTCGCACGCGCGCAAATTTTGTGGCCCGCTTTAACCCTGCGAAGATACGCGACAAAGCG
CAGCTGCTCGCCAATCTTTCCACCGGAGCGGAGCAAGTGATTGACGCGCGCTCCGCCGCCCGCTTCCACGCGGAAGAGAA
GGAAGCGCGTCCCGGACTTCGGTCCGGCCATATTCCCGGAAGTCTCAATCTTCCCTTCAATCTGATGACCGACCCGGCGA
CTGGCGAAATGAAATCGCCGCAGGCGCTTCGCGCGGCCTTTCTGCAGGCGGGGCTCGACTTCTCCCGTCCAGCCGTTGCG
TCCTGCGGCTCCGGCGTAACGGCATGCGCGCTGGTTTTCGCGCTCCATCTCCTGGGCAAGGAGGATGTAGCCGTCTATGA
CGGCGCGTGGGCCGAATGGGGACTGCCCGGCTCCACACCGGTTGAGCCCGCATGA

Upstream 100 bases:

>100_bases
ACATGCGAGCAAAAATTTGCAATATATGCAAAATTGTGCTCGGCCGACGGTCGCGCCAGTCATCTTGAAAATGGTTTGCG
CATTGAACAGGAGGTCTTCA

Downstream 100 bases:

>100_bases
ATGCGCAAAGCCCGCAAACGGCAAGGGCAGCGGCATTTGAGGCCTTCATGGCTGCCATTCGGCAGGTTCTGCCTGCCGAA
CGCATTCTCCTCGACCGGTT

Product: rhodanese-like protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQRQQNGSLVTTEWLAAHLDDPDLVLLDASFKLPGVAPTAEEDFSERHIPGAQFFDVDAIADHKNPLPHMLPPPEVFAEH
SSAFGISNGHTVIIYDTPGLMSAGRAWWMFRTFGHVNVAILDGGLKKWLAEGRPVTHEVRSRTRANFVARFNPAKIRDKA
QLLANLSTGAEQVIDARSAARFHAEEKEARPGLRSGHIPGSLNLPFNLMTDPATGEMKSPQALRAAFLQAGLDFSRPAVA
SCGSGVTACALVFALHLLGKEDVAVYDGAWAEWGLPGSTPVEPA

Sequences:

>Translated_284_residues
MQRQQNGSLVTTEWLAAHLDDPDLVLLDASFKLPGVAPTAEEDFSERHIPGAQFFDVDAIADHKNPLPHMLPPPEVFAEH
SSAFGISNGHTVIIYDTPGLMSAGRAWWMFRTFGHVNVAILDGGLKKWLAEGRPVTHEVRSRTRANFVARFNPAKIRDKA
QLLANLSTGAEQVIDARSAARFHAEEKEARPGLRSGHIPGSLNLPFNLMTDPATGEMKSPQALRAAFLQAGLDFSRPAVA
SCGSGVTACALVFALHLLGKEDVAVYDGAWAEWGLPGSTPVEPA
>Mature_284_residues
MQRQQNGSLVTTEWLAAHLDDPDLVLLDASFKLPGVAPTAEEDFSERHIPGAQFFDVDAIADHKNPLPHMLPPPEVFAEH
SSAFGISNGHTVIIYDTPGLMSAGRAWWMFRTFGHVNVAILDGGLKKWLAEGRPVTHEVRSRTRANFVARFNPAKIRDKA
QLLANLSTGAEQVIDARSAARFHAEEKEARPGLRSGHIPGSLNLPFNLMTDPATGEMKSPQALRAAFLQAGLDFSRPAVA
SCGSGVTACALVFALHLLGKEDVAVYDGAWAEWGLPGSTPVEPA

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=272, Percent_Identity=44.1176470588235, Blast_Score=234, Evalue=6e-62,
Organism=Homo sapiens, GI61835204, Length=272, Percent_Identity=44.1176470588235, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI194473681, Length=272, Percent_Identity=44.1176470588235, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI17402865, Length=274, Percent_Identity=43.7956204379562, Blast_Score=216, Evalue=2e-56,
Organism=Escherichia coli, GI87082121, Length=276, Percent_Identity=43.4782608695652, Blast_Score=234, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17561888, Length=290, Percent_Identity=25.8620689655172, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71997283, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115534702, Length=265, Percent_Identity=26.4150943396226, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559150, Length=245, Percent_Identity=25.3061224489796, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324825, Length=269, Percent_Identity=31.9702602230483, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 30673; Mature: 30673

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00380 RHODANESE_1 ; PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRQQNGSLVTTEWLAAHLDDPDLVLLDASFKLPGVAPTAEEDFSERHIPGAQFFDVDAI
CCCCCCCCEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCEEECHHH
ADHKNPLPHMLPPPEVFAEHSSAFGISNGHTVIIYDTPGLMSAGRAWWMFRTFGHVNVAI
HCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCEEEEE
LDGGLKKWLAEGRPVTHEVRSRTRANFVARFNPAKIRDKAQLLANLSTGAEQVIDARSAA
ECCHHHHHHHCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RFHAEEKEARPGLRSGHIPGSLNLPFNLMTDPATGEMKSPQALRAAFLQAGLDFSRPAVA
HHCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
SCGSGVTACALVFALHLLGKEDVAVYDGAWAEWGLPGSTPVEPA
HCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCCCCC
>Mature Secondary Structure
MQRQQNGSLVTTEWLAAHLDDPDLVLLDASFKLPGVAPTAEEDFSERHIPGAQFFDVDAI
CCCCCCCCEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCEEECHHH
ADHKNPLPHMLPPPEVFAEHSSAFGISNGHTVIIYDTPGLMSAGRAWWMFRTFGHVNVAI
HCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCEEEEE
LDGGLKKWLAEGRPVTHEVRSRTRANFVARFNPAKIRDKAQLLANLSTGAEQVIDARSAA
ECCHHHHHHHCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RFHAEEKEARPGLRSGHIPGSLNLPFNLMTDPATGEMKSPQALRAAFLQAGLDFSRPAVA
HHCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
SCGSGVTACALVFALHLLGKEDVAVYDGAWAEWGLPGSTPVEPA
HCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]