Click here to switch to the map view.

The map label for this gene is yofA [H]

Identifier: 110632765

GI number: 110632765

Start: 447410

End: 448345

Strand: Direct

Name: yofA [H]

Synonym: Meso_0404

Alternate gene names: 110632765

Gene position: 447410-448345 (Clockwise)

Preceding gene: 110632751

Following gene: 110632766

Centisome position: 10.14

GC content: 55.02

Gene sequence:

>936_bases
ATGACAGCGTCTGAGTTGGTTTCTTGCTTAGGAAGCGGGCGAATGAACACACGGTTTTTGGAGACGTTTGTGTGGGTGGC
GCGCTTGCGGAGTTTTAGCGCAGCGGCAGAACGGCTTAACAGTACCCAAGCGGCAATCTCGAACCGAATTCGCGCTCTAG
AGGCAGAACTCGGGGTGAAGTTGCTGGACCGAAACTCCCGCTCCGTAACGTTGACGCGGGAGGGGCGTGTTGCTTTCGCC
AAGGCCCAACGGATCGTAAATTTGGCGTCAGCCTTTGTACTTGACGTGAGCCACCCGGACGCCATCCAGGGCAGCGTTTC
GATCGGCATCATAGATACCATCATCCACACTTGGTTTCCGGATTTTGCCAAGTTGATGCGCGAAGCGTTCCCCATGTTGA
AATTGAGTTTAACGGTCGATGCAACGCCCAAGCTTTACCAACAGCTTCAACACGGGGAACTTGACTTGGCGTTCGGTGTC
GGGAGCGCCGCAAGCGACGGGTTTTATGCGGTCGAACTTGGAACCTTTGATTGCGTGTGGGTCGGCAGTCCGGCTAGTCG
TTTTTCCTCCCCGCCTACCTCAATAGCGGATATCGAGGACTGCCCGATTGTGAGTTATTCCGTGGGATCGGTTCCAGACC
AATCGTTGAGAGCGCTCCTCGGTAGACACGCCATTCCGTTAGAGAACCGGGTCTTCAATACCAACTCACTTCCGACAATC
ATCCATCTTGTGCGCGAAGGGGTTGGGATTGCCTACCTTCCCGAATGCATCATTCGTCCCCTGATCAGCTCTAAAGAGCT
AATCCTACTACCGATCGGCGAGAAGCTGGCGCCAATGACCTATCACGCGATCTATGCCGGGCATCATGAGGATCCGCTTC
CAGAACGAGTGGCGGCGATCGCTCGCGTCGCCAGCAGCAACTATCTCAATGGTTAG

Upstream 100 bases:

>100_bases
GGCGGCGCTGTCGGTCGGGTAGGCATTGTCACTCTAACGAGGCACCCAATCATTTCGCAAACGACAAAAAATGTGGCCTT
GTGATCAGGAATTTGAATAG

Downstream 100 bases:

>100_bases
TTCCACGCCTTGATAGACCCCTTGCGTCTAATCGCGATCGAAGGCGGATTCGGCTGCCGTACCAGGCCTAATCCGGCCGA
TTCATCAGTATGTTGCTGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTASELVSCLGSGRMNTRFLETFVWVARLRSFSAAAERLNSTQAAISNRIRALEAELGVKLLDRNSRSVTLTREGRVAFA
KAQRIVNLASAFVLDVSHPDAIQGSVSIGIIDTIIHTWFPDFAKLMREAFPMLKLSLTVDATPKLYQQLQHGELDLAFGV
GSAASDGFYAVELGTFDCVWVGSPASRFSSPPTSIADIEDCPIVSYSVGSVPDQSLRALLGRHAIPLENRVFNTNSLPTI
IHLVREGVGIAYLPECIIRPLISSKELILLPIGEKLAPMTYHAIYAGHHEDPLPERVAAIARVASSNYLNG

Sequences:

>Translated_311_residues
MTASELVSCLGSGRMNTRFLETFVWVARLRSFSAAAERLNSTQAAISNRIRALEAELGVKLLDRNSRSVTLTREGRVAFA
KAQRIVNLASAFVLDVSHPDAIQGSVSIGIIDTIIHTWFPDFAKLMREAFPMLKLSLTVDATPKLYQQLQHGELDLAFGV
GSAASDGFYAVELGTFDCVWVGSPASRFSSPPTSIADIEDCPIVSYSVGSVPDQSLRALLGRHAIPLENRVFNTNSLPTI
IHLVREGVGIAYLPECIIRPLISSKELILLPIGEKLAPMTYHAIYAGHHEDPLPERVAAIARVASSNYLNG
>Mature_310_residues
TASELVSCLGSGRMNTRFLETFVWVARLRSFSAAAERLNSTQAAISNRIRALEAELGVKLLDRNSRSVTLTREGRVAFAK
AQRIVNLASAFVLDVSHPDAIQGSVSIGIIDTIIHTWFPDFAKLMREAFPMLKLSLTVDATPKLYQQLQHGELDLAFGVG
SAASDGFYAVELGTFDCVWVGSPASRFSSPPTSIADIEDCPIVSYSVGSVPDQSLRALLGRHAIPLENRVFNTNSLPTII
HLVREGVGIAYLPECIIRPLISSKELILLPIGEKLAPMTYHAIYAGHHEDPLPERVAAIARVASSNYLNG

Specific function: Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=265, Percent_Identity=29.0566037735849, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=28.6689419795222, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082132, Length=280, Percent_Identity=26.0714285714286, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=26.2068965517241, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994962, Length=232, Percent_Identity=26.2931034482759, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789506, Length=278, Percent_Identity=26.2589928057554, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=275, Percent_Identity=28.3636363636364, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=25.1028806584362, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=282, Percent_Identity=27.3049645390071, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786713, Length=261, Percent_Identity=27.9693486590038, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786508, Length=268, Percent_Identity=26.1194029850746, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788297, Length=261, Percent_Identity=27.2030651340996, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788481, Length=248, Percent_Identity=25, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790262, Length=301, Percent_Identity=22.9235880398671, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=26.7148014440433, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788626, Length=246, Percent_Identity=25.609756097561, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33828; Mature: 33697

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASELVSCLGSGRMNTRFLETFVWVARLRSFSAAAERLNSTQAAISNRIRALEAELGVK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLDRNSRSVTLTREGRVAFAKAQRIVNLASAFVLDVSHPDAIQGSVSIGIIDTIIHTWFP
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCEEHHHHHHHHHHHCH
DFAKLMREAFPMLKLSLTVDATPKLYQQLQHGELDLAFGVGSAASDGFYAVELGTFDCVW
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCEEEEE
VGSPASRFSSPPTSIADIEDCPIVSYSVGSVPDQSLRALLGRHAIPLENRVFNTNSLPTI
ECCCHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEECCCCHHHH
IHLVREGVGIAYLPECIIRPLISSKELILLPIGEKLAPMTYHAIYAGHHEDPLPERVAAI
HHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
ARVASSNYLNG
HHHHHCCCCCC
>Mature Secondary Structure 
TASELVSCLGSGRMNTRFLETFVWVARLRSFSAAAERLNSTQAAISNRIRALEAELGVK
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLDRNSRSVTLTREGRVAFAKAQRIVNLASAFVLDVSHPDAIQGSVSIGIIDTIIHTWFP
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCEEHHHHHHHHHHHCH
DFAKLMREAFPMLKLSLTVDATPKLYQQLQHGELDLAFGVGSAASDGFYAVELGTFDCVW
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCEEEEE
VGSPASRFSSPPTSIADIEDCPIVSYSVGSVPDQSLRALLGRHAIPLENRVFNTNSLPTI
ECCCHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEECCCCHHHH
IHLVREGVGIAYLPECIIRPLISSKELILLPIGEKLAPMTYHAIYAGHHEDPLPERVAAI
HHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
ARVASSNYLNG
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA