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The map label for this gene is lutA [H]

Identifier: 110632728

GI number: 110632728

Start: 410545

End: 411324

Strand: Direct

Name: lutA [H]

Synonym: Meso_0367

Alternate gene names: 110632728

Gene position: 410545-411324 (Clockwise)

Preceding gene: 110632727

Following gene: 110632729

Centisome position: 9.3

GC content: 61.54

Gene sequence:

>780_bases
TTGCAAGAAGATGTGAAGAAGAAGAACCCCCGCGTGGGCCTGTTTGTGACCTGCCTTGTCGATCTCTTCCGGCCGACGGT
GGGGTTCGCATCCGTCAAACTCCTGGAGGATGCAGGCTGCGAGGTGGAGGTGCCGATGGCACAGACCTGCTGCGGCCAGC
CCGCGTACAATTCCGGCGACCGTTCCGACACGATCGAGATTGCCAAAAACACGATCGAGACCTTTGAAGGGTACGACTAT
GTCGTGGCGCCTTCCGGCTCCTGCGCGGGCATGTTGAAGAAGCATTATCCCGGTCTCTTCAAGGGGGATGCTCATTGGGA
GGCACGCGCTGCGGCCTTTTCGGCTCGGGTGCACGAGCTGGTGAGCTTTTTGGTCGATGTCATGGGCGTGAAGGATGTCG
CAGTCGCCCACGCAGGCAGCGTCACCTATCACGATTCCTGCTCGGGCCTGCGCGAGCTCGGCATACGCGAGCAGCCGCGC
CGGCTTCTCTCCTCTATCGCCGGGCTTAAGCTCCAGGAGATGCGGGACGCGGACACCTGCTGCGGTTTCGGCGGCACCTT
CTGCGTCAAATATCCGGACATTTCCAACAGGATCGTCGAGGAAAAGACGGCGAATATCAGGGCAACCGGAGCCGAAACGC
TGCTTGCGGGCGATCTCGGCTGCCTCATGAACATGGCGGGAAAGCTTCAGCGTCAGGGCGCCGACGTGAAGGTGCGCCAT
GTGGCCGAGGTGCTCGCCGGCATGGTGGATGGGCCGGCAATCGGGAAGGATAAGCGCTGA

Upstream 100 bases:

>100_bases
CTCCATCGGTCCGACGCGCAGGCTCTTGCCCGGCAAACCGGACCGAAAACCTCCCGCACAAAGCGCTCGGCCGCTGCTGA
CCGTGAGATAGGGTGATCTA

Downstream 100 bases:

>100_bases
TGCAGATTACGTCACCGGCCTTCAAGGAAAATTCGCGTCAGGCGCTTTCGGATGCGCAGCTACAGAAGGCGCTCGGCAAT
GTGCGCTCCGGCTTCATCGA

Product: protein of unknown function DUF224, cysteine-rich region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MQEDVKKKNPRVGLFVTCLVDLFRPTVGFASVKLLEDAGCEVEVPMAQTCCGQPAYNSGDRSDTIEIAKNTIETFEGYDY
VVAPSGSCAGMLKKHYPGLFKGDAHWEARAAAFSARVHELVSFLVDVMGVKDVAVAHAGSVTYHDSCSGLRELGIREQPR
RLLSSIAGLKLQEMRDADTCCGFGGTFCVKYPDISNRIVEEKTANIRATGAETLLAGDLGCLMNMAGKLQRQGADVKVRH
VAEVLAGMVDGPAIGKDKR

Sequences:

>Translated_259_residues
MQEDVKKKNPRVGLFVTCLVDLFRPTVGFASVKLLEDAGCEVEVPMAQTCCGQPAYNSGDRSDTIEIAKNTIETFEGYDY
VVAPSGSCAGMLKKHYPGLFKGDAHWEARAAAFSARVHELVSFLVDVMGVKDVAVAHAGSVTYHDSCSGLRELGIREQPR
RLLSSIAGLKLQEMRDADTCCGFGGTFCVKYPDISNRIVEEKTANIRATGAETLLAGDLGCLMNMAGKLQRQGADVKVRH
VAEVLAGMVDGPAIGKDKR
>Mature_259_residues
MQEDVKKKNPRVGLFVTCLVDLFRPTVGFASVKLLEDAGCEVEVPMAQTCCGQPAYNSGDRSDTIEIAKNTIETFEGYDY
VVAPSGSCAGMLKKHYPGLFKGDAHWEARAAAFSARVHELVSFLVDVMGVKDVAVAHAGSVTYHDSCSGLRELGIREQPR
RLLSSIAGLKLQEMRDADTCCGFGGTFCVKYPDISNRIVEEKTANIRATGAETLLAGDLGCLMNMAGKLQRQGADVKVRH
VAEVLAGMVDGPAIGKDKR

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=235, Percent_Identity=44.2553191489362, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI48994913, Length=240, Percent_Identity=21.25, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 27904; Mature: 27904

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEDVKKKNPRVGLFVTCLVDLFRPTVGFASVKLLEDAGCEVEVPMAQTCCGQPAYNSGD
CCCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCHHHHHCCCCCCCCCC
RSDTIEIAKNTIETFEGYDYVVAPSGSCAGMLKKHYPGLFKGDAHWEARAAAFSARVHEL
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VSFLVDVMGVKDVAVAHAGSVTYHDSCSGLRELGIREQPRRLLSSIAGLKLQEMRDADTC
HHHHHHHHCHHHHHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCHHHH
CGFGGTFCVKYPDISNRIVEEKTANIRATGAETLLAGDLGCLMNMAGKLQRQGADVKVRH
CCCCCEEEEECCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAEVLAGMVDGPAIGKDKR
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQEDVKKKNPRVGLFVTCLVDLFRPTVGFASVKLLEDAGCEVEVPMAQTCCGQPAYNSGD
CCCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCHHHHHCCCCCCCCCC
RSDTIEIAKNTIETFEGYDYVVAPSGSCAGMLKKHYPGLFKGDAHWEARAAAFSARVHEL
CHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VSFLVDVMGVKDVAVAHAGSVTYHDSCSGLRELGIREQPRRLLSSIAGLKLQEMRDADTC
HHHHHHHHCHHHHHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCHHHH
CGFGGTFCVKYPDISNRIVEEKTANIRATGAETLLAGDLGCLMNMAGKLQRQGADVKVRH
CCCCCEEEEECCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAEVLAGMVDGPAIGKDKR
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA