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The map label for this gene is tag [H]

Identifier: 110632720

GI number: 110632720

Start: 401818

End: 402456

Strand: Reverse

Name: tag [H]

Synonym: Meso_0359

Alternate gene names: 110632720

Gene position: 402456-401818 (Counterclockwise)

Preceding gene: 110632722

Following gene: 110632719

Centisome position: 9.12

GC content: 56.18

Gene sequence:

>639_bases
ATGATTGAAGAGAAGACCGGCCTGATCGTGGGAGATGACGGGAAGACACGCTGCTTCTGGCATGCGAACCTGCCTGACTA
CATGGCTTACCATGATCATGAATGGGGAAGGCCGGTCAGCGACGATCGCAGGCTCTTCGAAAAGCTGTGTCTTGAAGGTT
TTCAGTCAGGCCTTTCATGGCTTACGATCCTGCGGAAAAGAGAGAACTTCCGCGAAGCTTTCGAAGATTTCGACTTGGAG
CGCGTGGCGCGCTTCACGGACGAGGATGTCGATCGCCTTCTGAAGAATGCGGGCATCATTCGGCACGGCGGAAAGATCCG
TTCCACGATCAACAACGCACGCCGAGCCATCGAGCTTTGCGAAAAAGAGGGATCACTCTCCCGCTATTTCTGGCGACACG
AGCCTGGACCTGAGGAGCGGCCGCAAGAGCTCGACTACGCAACGCTCCGGACCCTCGGCAAGACCGAGGCTTCGACCCGC
ATTTCAAAAGATCTCAAAAAGCGCGGGTGGACTTTTGTCGGCCCGACCACCATCTACGCCTTCATGCAGGCTATGGGCCT
CGTCAACGATCACATCGAAGGATGCCACTTCCGCGAGGAAATCGAAAAGGACCGCAGGCGCTTTCAAAGGCCGGTCTAA

Upstream 100 bases:

>100_bases
AGTGCGATATGTCGGGAAAACTGATCGATGTGGTTATCGCCCGGTTCAAAAATCCGGTGAACAAATCCTTAATCCCCTTA
AAAAAATGCGGTGAGTTTCG

Downstream 100 bases:

>100_bases
ATTCGGGATAACGGCCGAAACGATAAATCGGCCATGCGGTGCCGAAGTTGATCCAAGCCGCAACTCGCTTGACTCTGACA
CCTATCCTGACTATCTCGGC

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIEEKTGLIVGDDGKTRCFWHANLPDYMAYHDHEWGRPVSDDRRLFEKLCLEGFQSGLSWLTILRKRENFREAFEDFDLE
RVARFTDEDVDRLLKNAGIIRHGGKIRSTINNARRAIELCEKEGSLSRYFWRHEPGPEERPQELDYATLRTLGKTEASTR
ISKDLKKRGWTFVGPTTIYAFMQAMGLVNDHIEGCHFREEIEKDRRRFQRPV

Sequences:

>Translated_212_residues
MIEEKTGLIVGDDGKTRCFWHANLPDYMAYHDHEWGRPVSDDRRLFEKLCLEGFQSGLSWLTILRKRENFREAFEDFDLE
RVARFTDEDVDRLLKNAGIIRHGGKIRSTINNARRAIELCEKEGSLSRYFWRHEPGPEERPQELDYATLRTLGKTEASTR
ISKDLKKRGWTFVGPTTIYAFMQAMGLVNDHIEGCHFREEIEKDRRRFQRPV
>Mature_212_residues
MIEEKTGLIVGDDGKTRCFWHANLPDYMAYHDHEWGRPVSDDRRLFEKLCLEGFQSGLSWLTILRKRENFREAFEDFDLE
RVARFTDEDVDRLLKNAGIIRHGGKIRSTINNARRAIELCEKEGSLSRYFWRHEPGPEERPQELDYATLRTLGKTEASTR
ISKDLKKRGWTFVGPTTIYAFMQAMGLVNDHIEGCHFREEIEKDRRRFQRPV

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=48.8888888888889, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 25009; Mature: 25009

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEKTGLIVGDDGKTRCFWHANLPDYMAYHDHEWGRPVSDDRRLFEKLCLEGFQSGLSW
CCCCCCCEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LTILRKRENFREAFEDFDLERVARFTDEDVDRLLKNAGIIRHGGKIRSTINNARRAIELC
HHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHH
EKEGSLSRYFWRHEPGPEERPQELDYATLRTLGKTEASTRISKDLKKRGWTFVGPTTIYA
HHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHH
FMQAMGLVNDHIEGCHFREEIEKDRRRFQRPV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEEKTGLIVGDDGKTRCFWHANLPDYMAYHDHEWGRPVSDDRRLFEKLCLEGFQSGLSW
CCCCCCCEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LTILRKRENFREAFEDFDLERVARFTDEDVDRLLKNAGIIRHGGKIRSTINNARRAIELC
HHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHH
EKEGSLSRYFWRHEPGPEERPQELDYATLRTLGKTEASTRISKDLKKRGWTFVGPTTIYA
HHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHH
FMQAMGLVNDHIEGCHFREEIEKDRRRFQRPV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]