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The map label for this gene is flhA [H]

Identifier: 110632633

GI number: 110632633

Start: 310927

End: 313014

Strand: Reverse

Name: flhA [H]

Synonym: Meso_0272

Alternate gene names: 110632633

Gene position: 313014-310927 (Counterclockwise)

Preceding gene: 110632634

Following gene: 110632632

Centisome position: 7.09

GC content: 60.63

Gene sequence:

>2088_bases
ATGGCTGCAACCGAGAGCATACTTATCCCGCAACCGGCGAAGCATGGCCGCGATATCGGCTTCGCCCTCGGCGTGGTTAT
CATCCTCTCAGTCCTTTTCCTGCCGATCCCGGCCTTCCTGATCGATATCGGGCTCGCATTCTCCATCGCTTTTTCCGTTC
TCATCCTGATGGTGGCGCTCTGGATACAGCGGCCCCTCGACTTCTCGTCCTTTCCAACCATCCTCCTCATTTCCACCATG
CTGCGCCTGTCGCTCAACATTGCCACGACGCGCATGATCCTTTCGGAAGGGAATGAGGGAACGAACGCAGCCGGGTATGT
GATCGGCGGCTTTGCCCAACTCGTGATGGGCGGCGATTTCGTTATCGGACTAATCATCTTCCTCATCCTGATCGTGGTGA
ACTTCGTCGTCATCACAAAAGGCTCCACCCGTATCGCCGAAGTCGGCGCGCGCTTTACGCTCGATGCCATTCCCGGCAAA
CAGATGTCGATCGACGCCGATCTTTCAGCAGGCCTTATCGACGAGAAGGAAGCGCAGAACCGCCGGCGGGAACTGGAGGA
GGAAAGCGCATTTTTCGGCGCGATGGACGGCGCGTCGAAGTTCGTGCGCGGGGATGCGATCGCCGGCCTCATCATCACCG
CCATCAATATCGTCGGCGGCATCGCCATTGGCTATGCCAGGCACGGGATGGAGCTCGGCGACGCGGCAGACGTCTTCACC
AAGCTCTCGGTGGGCGACGGGCTTGTCTCGCAGATCCCGGCCCTCATCGTCTCCCTCGCGGCGGGTCTTCTGGTCTCCAA
GGGCGGCACGCGAGGCTCCGCCGAACAGGCGGTCTTCGGCCAGCTCGGCGCCTATCCGCGTGCGCTCTTCGTTGCGGCCA
TGCTTCTGGCGCTGCTGGCCCTGATGCCGGGCCTGCCTGCCCTGCCCTTCCTTGCGCTCGGCGGTGTCATGGCCGGCCTT
GCTTATCTGTTACCGCAGCAAGAAAGGGAGCGAGCGGCAGAGGCCGAAGAAGCAAAGCGGCAACAGCAGGCCGCGGCCAC
GGAAGAAGAGCAGAACTCCGTCAAATCCTCGCTCAAGACGGCCGAGATCGAGCTTCTCATCGGCAAGCAGCTCTCCACGC
GCCTGATTGCCTCGCATCAGGAGCTTGCATACCGCATGAACAAGATGCGGAAGAAATTCGCGACGCAGTACGGCTTCGTC
GTTCCCGAGGTGCGCCTTGCGGACGAATTCTCCATTCCGCCCAAAAGCTACCAGATCAAGATTCACGGCACGGTCGTGTC
GGAACACCAGTTACGCGTGGGCGAACTGATGGTGCTTCTCGGCAACAAGCCCGCGCCATCCCTCCCCGGCGAGGAGGTGA
AGGAACCTGCATTCGGCATGCGCGCTTATTCCGTCCCCGAGATGTTTGCCGAGGACCTGAAGAATGAACGGCTTGCCTAT
GCGGACAATATGGCGGTCCTGCTCACGCATCTCTCGGAGGTCATTCGCAACAATCTACCGCAACTGCTTTCCTATAAGGA
CATGAAGGCGCTGATCGAGCGGCTGGACCCCGAATACCGGAAGCTTTGCGATGAGATCTGCTCGTCTCACATCACTTATC
CGGGCTTGCAGGCAGTGCTGAAATTGCTGCTTGCCGAACGCATTTCGATCCGCAACCTGCACCTGATCATCGAAGCCATC
GCAGAGATCGCGCCGCATATCCGCCGCACGGAGCAGATCGTCGAGCATGTGCGCATCCGCATGGCGCAGCAGATCTGCGG
TGATCTCAGCGACGGCGGAGTGCTCAAAGTGCTGCGGCTCGGCAGCCGCTGGGATCTCGCCTTCCACCAGGCGCTGAAGC
GCGACCCGAAAGGCGAGGTGCGCGAATTCGATATCGACCCGCGCCAACTTGAGGAATTCGGCCAGGAGGCGGCAAAAGCC
GTCAAGACTCATCTCGACGCCGGTGAACGCTTCGTGCTGGTGACCGCGCCCGAAGCCAGGCCCTATGTGCGCATGATCAT
CGAACGACTATTCCCGACCCTGCCGGTGCTCAGCCATGTGGAGATCGCAAAGGGCGTGGAGATCCAGGTGCTGGGGAGCG
TGTCCTAA

Upstream 100 bases:

>100_bases
ATCGAGAACGGATTTTAAACTTTCGGCCTGCCGATTCAGGCATTGTTTCCGCCCTCGCACAAGCTTCAGCCGCTAAGTTC
ATGCTTCGATGGAGGCATGA

Downstream 100 bases:

>100_bases
ATCAAAGATGCTTTGCTCTTTCGCACCTCTCTCTGGCCTGCCGGCCATCATCCGCCGCAAGAGCGGGGATTGCGGAAGCT
CCTGCTCCCCTTCCGTCGCC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MAATESILIPQPAKHGRDIGFALGVVIILSVLFLPIPAFLIDIGLAFSIAFSVLILMVALWIQRPLDFSSFPTILLISTM
LRLSLNIATTRMILSEGNEGTNAAGYVIGGFAQLVMGGDFVIGLIIFLILIVVNFVVITKGSTRIAEVGARFTLDAIPGK
QMSIDADLSAGLIDEKEAQNRRRELEEESAFFGAMDGASKFVRGDAIAGLIITAINIVGGIAIGYARHGMELGDAADVFT
KLSVGDGLVSQIPALIVSLAAGLLVSKGGTRGSAEQAVFGQLGAYPRALFVAAMLLALLALMPGLPALPFLALGGVMAGL
AYLLPQQERERAAEAEEAKRQQQAAATEEEQNSVKSSLKTAEIELLIGKQLSTRLIASHQELAYRMNKMRKKFATQYGFV
VPEVRLADEFSIPPKSYQIKIHGTVVSEHQLRVGELMVLLGNKPAPSLPGEEVKEPAFGMRAYSVPEMFAEDLKNERLAY
ADNMAVLLTHLSEVIRNNLPQLLSYKDMKALIERLDPEYRKLCDEICSSHITYPGLQAVLKLLLAERISIRNLHLIIEAI
AEIAPHIRRTEQIVEHVRIRMAQQICGDLSDGGVLKVLRLGSRWDLAFHQALKRDPKGEVREFDIDPRQLEEFGQEAAKA
VKTHLDAGERFVLVTAPEARPYVRMIIERLFPTLPVLSHVEIAKGVEIQVLGSVS

Sequences:

>Translated_695_residues
MAATESILIPQPAKHGRDIGFALGVVIILSVLFLPIPAFLIDIGLAFSIAFSVLILMVALWIQRPLDFSSFPTILLISTM
LRLSLNIATTRMILSEGNEGTNAAGYVIGGFAQLVMGGDFVIGLIIFLILIVVNFVVITKGSTRIAEVGARFTLDAIPGK
QMSIDADLSAGLIDEKEAQNRRRELEEESAFFGAMDGASKFVRGDAIAGLIITAINIVGGIAIGYARHGMELGDAADVFT
KLSVGDGLVSQIPALIVSLAAGLLVSKGGTRGSAEQAVFGQLGAYPRALFVAAMLLALLALMPGLPALPFLALGGVMAGL
AYLLPQQERERAAEAEEAKRQQQAAATEEEQNSVKSSLKTAEIELLIGKQLSTRLIASHQELAYRMNKMRKKFATQYGFV
VPEVRLADEFSIPPKSYQIKIHGTVVSEHQLRVGELMVLLGNKPAPSLPGEEVKEPAFGMRAYSVPEMFAEDLKNERLAY
ADNMAVLLTHLSEVIRNNLPQLLSYKDMKALIERLDPEYRKLCDEICSSHITYPGLQAVLKLLLAERISIRNLHLIIEAI
AEIAPHIRRTEQIVEHVRIRMAQQICGDLSDGGVLKVLRLGSRWDLAFHQALKRDPKGEVREFDIDPRQLEEFGQEAAKA
VKTHLDAGERFVLVTAPEARPYVRMIIERLFPTLPVLSHVEIAKGVEIQVLGSVS
>Mature_694_residues
AATESILIPQPAKHGRDIGFALGVVIILSVLFLPIPAFLIDIGLAFSIAFSVLILMVALWIQRPLDFSSFPTILLISTML
RLSLNIATTRMILSEGNEGTNAAGYVIGGFAQLVMGGDFVIGLIIFLILIVVNFVVITKGSTRIAEVGARFTLDAIPGKQ
MSIDADLSAGLIDEKEAQNRRRELEEESAFFGAMDGASKFVRGDAIAGLIITAINIVGGIAIGYARHGMELGDAADVFTK
LSVGDGLVSQIPALIVSLAAGLLVSKGGTRGSAEQAVFGQLGAYPRALFVAAMLLALLALMPGLPALPFLALGGVMAGLA
YLLPQQERERAAEAEEAKRQQQAAATEEEQNSVKSSLKTAEIELLIGKQLSTRLIASHQELAYRMNKMRKKFATQYGFVV
PEVRLADEFSIPPKSYQIKIHGTVVSEHQLRVGELMVLLGNKPAPSLPGEEVKEPAFGMRAYSVPEMFAEDLKNERLAYA
DNMAVLLTHLSEVIRNNLPQLLSYKDMKALIERLDPEYRKLCDEICSSHITYPGLQAVLKLLLAERISIRNLHLIIEAIA
EIAPHIRRTEQIVEHVRIRMAQQICGDLSDGGVLKVLRLGSRWDLAFHQALKRDPKGEVREFDIDPRQLEEFGQEAAKAV
KTHLDAGERFVLVTAPEARPYVRMIIERLFPTLPVLSHVEIAKGVEIQVLGSVS

Specific function: Required for formation of the rod structure of the flagellar apparatus. May constitute the export apparatus of flagellin. The flagellum is required to cause a persistent disease in a murine model of infection [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=676, Percent_Identity=36.8343195266272, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75797; Mature: 75666

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATESILIPQPAKHGRDIGFALGVVIILSVLFLPIPAFLIDIGLAFSIAFSVLILMVAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIQRPLDFSSFPTILLISTMLRLSLNIATTRMILSEGNEGTNAAGYVIGGFAQLVMGGDF
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHH
VIGLIIFLILIVVNFVVITKGSTRIAEVGARFTLDAIPGKQMSIDADLSAGLIDEKEAQN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCHHHHHH
RRRELEEESAFFGAMDGASKFVRGDAIAGLIITAINIVGGIAIGYARHGMELGDAADVFT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLSVGDGLVSQIPALIVSLAAGLLVSKGGTRGSAEQAVFGQLGAYPRALFVAAMLLALLA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LMPGLPALPFLALGGVMAGLAYLLPQQERERAAEAEEAKRQQQAAATEEEQNSVKSSLKT
HCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEIELLIGKQLSTRLIASHQELAYRMNKMRKKFATQYGFVVPEVRLADEFSIPPKSYQIK
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEE
IHGTVVSEHQLRVGELMVLLGNKPAPSLPGEEVKEPAFGMRAYSVPEMFAEDLKNERLAY
EEEEEECCCHHHHHHEEEEECCCCCCCCCCHHHCCCHHCCHHHCCHHHHHHHHCCCCHHH
ADNMAVLLTHLSEVIRNNLPQLLSYKDMKALIERLDPEYRKLCDEICSSHITYPGLQAVL
HCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHH
KLLLAERISIRNLHLIIEAIAEIAPHIRRTEQIVEHVRIRMAQQICGDLSDGGVLKVLRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GSRWDLAFHQALKRDPKGEVREFDIDPRQLEEFGQEAAKAVKTHLDAGERFVLVTAPEAR
CCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
PYVRMIIERLFPTLPVLSHVEIAKGVEIQVLGSVS
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure 
AATESILIPQPAKHGRDIGFALGVVIILSVLFLPIPAFLIDIGLAFSIAFSVLILMVAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIQRPLDFSSFPTILLISTMLRLSLNIATTRMILSEGNEGTNAAGYVIGGFAQLVMGGDF
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHH
VIGLIIFLILIVVNFVVITKGSTRIAEVGARFTLDAIPGKQMSIDADLSAGLIDEKEAQN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCHHHHHH
RRRELEEESAFFGAMDGASKFVRGDAIAGLIITAINIVGGIAIGYARHGMELGDAADVFT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLSVGDGLVSQIPALIVSLAAGLLVSKGGTRGSAEQAVFGQLGAYPRALFVAAMLLALLA
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LMPGLPALPFLALGGVMAGLAYLLPQQERERAAEAEEAKRQQQAAATEEEQNSVKSSLKT
HCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEIELLIGKQLSTRLIASHQELAYRMNKMRKKFATQYGFVVPEVRLADEFSIPPKSYQIK
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEE
IHGTVVSEHQLRVGELMVLLGNKPAPSLPGEEVKEPAFGMRAYSVPEMFAEDLKNERLAY
EEEEEECCCHHHHHHEEEEECCCCCCCCCCHHHCCCHHCCHHHCCHHHHHHHHCCCCHHH
ADNMAVLLTHLSEVIRNNLPQLLSYKDMKALIERLDPEYRKLCDEICSSHITYPGLQAVL
HCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHH
KLLLAERISIRNLHLIIEAIAEIAPHIRRTEQIVEHVRIRMAQQICGDLSDGGVLKVLRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GSRWDLAFHQALKRDPKGEVREFDIDPRQLEEFGQEAAKAVKTHLDAGERFVLVTAPEAR
CCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
PYVRMIIERLFPTLPVLSHVEIAKGVEIQVLGSVS
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]