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The map label for this gene is speE

Identifier: 109947728

GI number: 109947728

Start: 1037757

End: 1038545

Strand: Reverse

Name: speE

Synonym: Hac_1202

Alternate gene names: 109947728

Gene position: 1038545-1037757 (Counterclockwise)

Preceding gene: 109947729

Following gene: 109947727

Centisome position: 66.83

GC content: 34.47

Gene sequence:

>789_bases
ATGTGGATCACCCAAGAAATCACGCCGTATTTGCGTAAAGAATACACGATAGAAGCGAAATTATTAGATGTTAGAAGCGA
TCATAATATCTTAGAGATTTTTAAATCTAATGATTTTGGCGAGATTGCGATGCTTAATTCCCAGTTGTTATTCAAGAACT
TTTTGCATATTGAAAGCGAATTGCTCGCTCATATGGGAGGTTGCACTAAAAAAGAGCTTAAAGAAGTTTTGATTGTAGAT
GGGTTTGATTTGGAATTAGCCCACCAGCTTTTTAAATACGACACGCATGTGGATTTTGTGCAAGCAGATGAAAAGATCTT
GGATAGTTTTATTAGTTTTTTTCCCCATTTCCATGGAGTGAAAAATAATAAGAATTTCACGCATGCTAAACAATTTTTAG
ATTTAGACATTAAAAAATACGATTTAATTGTTTGTTTGCAAGAGCCGGACAAGCATAAAATTGATGGTTTAAAAAGAACG
CTTAAAGAAGATGGCGTGTTTATTTCGGTAGCCAAACACCCACTATTAGAGCATGTGAGCATGCAAAACGCCCTTAAAAA
CATGGGCGAGTTTTTTTCTATTGTCATGCCTTTTGTAGCACCTTTAAGGATTTTGAGCAATAAGGGTTATATTTATGCGT
CTTTAAAAACCCACCCCTTAAAAGATTTGATCGCACAAAAAATAGAAGCACTAAAAAATGTGGGATACTATAACGAAGAC
ATTCATAGGGCCGCATTCGCTCTCCCTAAAAATTTACAAGAAATCCTTAAAGAAAATATCAAATCTTAA

Upstream 100 bases:

>100_bases
TTAGAATGTCTTAAGGAAAGTTAGGGCTTTTGTTGATTTAGATTTTTTGGGTAGCATATAAATTAAAGAGATAAGTATTA
CAAAGCAATGAAGGATTTTA

Downstream 100 bases:

>100_bases
AATGGTTTTAAAAAACGCTATTGCTCTCACAGGGGGGATAGGCACCGGTAAAAGCACCACCATTAAATTACTAGAATCGC
AAGGCTATCAAATCTTAGAT

Product: spermidine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESELLAHMGGCTKKELKEVLIVD
GFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGVKNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRT
LKEDGVFISVAKHPLLEHVSMQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNED
IHRAAFALPKNLQEILKENIKS

Sequences:

>Translated_262_residues
MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESELLAHMGGCTKKELKEVLIVD
GFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGVKNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRT
LKEDGVFISVAKHPLLEHVSMQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNED
IHRAAFALPKNLQEILKENIKS
>Mature_262_residues
MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESELLAHMGGCTKKELKEVLIVD
GFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGVKNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRT
LKEDGVFISVAKHPLLEHVSMQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNED
IHRAAFALPKNLQEILKENIKS

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEE_HELAH (Q17WL9)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664956.1
- ProteinModelPortal:   Q17WL9
- SMR:   Q17WL9
- STRING:   Q17WL9
- GeneID:   4177461
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1202
- NMPDR:   fig|382638.8.peg.1167
- eggNOG:   COG0421
- HOGENOM:   HBG501836
- OMA:   ISFFPHF
- ProtClustDB:   PRK00536
- BioCyc:   HACI382638:HAC_1202-MONOMER
- HAMAP:   MF_00198
- InterPro:   IPR001045
- PANTHER:   PTHR11558

Pfam domain/function: PF01564 Spermine_synth

EC number: =2.5.1.16

Molecular weight: Translated: 30359; Mature: 30359

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01330 SPERMIDINE_SYNTHASE_1; PS51006 SPERMIDINE_SYNTHASE_2

Important sites: BINDING 29-29 BINDING 83-83 BINDING 101-101 BINDING 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESE
CCCCHHHHHHHHHHHEEEHEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGV
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
KNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRTLKEDGVFISVAKHPLLEHVS
CCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHH
MQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
IHRAAFALPKNLQEILKENIKS
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESE
CCCCHHHHHHHHHHHEEEHEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGV
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
KNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRTLKEDGVFISVAKHPLLEHVS
CCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHH
MQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
IHRAAFALPKNLQEILKENIKS
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA