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The map label for this gene is coaE [H]

Identifier: 109947727

GI number: 109947727

Start: 1037153

End: 1037755

Strand: Reverse

Name: coaE [H]

Synonym: Hac_1201

Alternate gene names: 109947727

Gene position: 1037755-1037153 (Counterclockwise)

Preceding gene: 109947728

Following gene: 109947725

Centisome position: 66.78

GC content: 35.99

Gene sequence:

>603_bases
ATGGTTTTAAAAAACGCTATTGCTCTCACAGGGGGGATAGGCACCGGTAAAAGCACCACCATTAAATTACTAGAATCGCA
AGGCTATCAAATCTTAGATGCGGATAAAATCGCCCATCAATTATTACAAGAGCATCGGCTAGAGATCGCCCAACATTTTG
GATCAAGTATTTTAGAAAAGGATATTCTTAACAGAAAAAAACTTGGCACGATCGTGTTTAAAGACTCTAATGAGTTAAAA
TGGCTAGAAAATTTTTTGCACCCCTTGATCCGTGAATGCATGCTAAAAAAAGCGCACGAATTAGAAAAAAACCATCAAGC
GTATTTTTTAGACATTCCTTTGTTTTTTGAAGTGGGGGGTAAAGAACGCTATCCTGTGAGTAAAGTGGTCTTAATCTATG
CACCTAGGGCTTTACAAATTGAGCGCCTTTTAGAGCGAGACAAACTCAAAGAAACTGAAATCTTGCAACGCCTAAATTGT
CAAATGGATATAGAGCAAAAACGCTTGATGAGCGATTATGTTATAGACAATAGTTTTAGTTTAAAAGATTTAGCTAAGCA
GGTTGAATGTTTTTTAAAAAATCTTGGTTTTGTTTCCAATTAA

Upstream 100 bases:

>100_bases
CTAAAAAATGTGGGATACTATAACGAAGACATTCATAGGGCCGCATTCGCTCTCCCTAAAAATTTACAAGAAATCCTTAA
AGAAAATATCAAATCTTAAA

Downstream 100 bases:

>100_bases
ATGTTGAAAATTTAAAAAATGCTCAAAGGTATTTTTTACAACCAATATCAAAGAGCTTGATTTTAATCAAGCGATAACCC
CTTGAAAAAAGCGGTCTTCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLKNAIALTGGIGTGKSTTIKLLESQGYQILDADKIAHQLLQEHRLEIAQHFGSSILEKDILNRKKLGTIVFKDSNELK
WLENFLHPLIRECMLKKAHELEKNHQAYFLDIPLFFEVGGKERYPVSKVVLIYAPRALQIERLLERDKLKETEILQRLNC
QMDIEQKRLMSDYVIDNSFSLKDLAKQVECFLKNLGFVSN

Sequences:

>Translated_200_residues
MVLKNAIALTGGIGTGKSTTIKLLESQGYQILDADKIAHQLLQEHRLEIAQHFGSSILEKDILNRKKLGTIVFKDSNELK
WLENFLHPLIRECMLKKAHELEKNHQAYFLDIPLFFEVGGKERYPVSKVVLIYAPRALQIERLLERDKLKETEILQRLNC
QMDIEQKRLMSDYVIDNSFSLKDLAKQVECFLKNLGFVSN
>Mature_200_residues
MVLKNAIALTGGIGTGKSTTIKLLESQGYQILDADKIAHQLLQEHRLEIAQHFGSSILEKDILNRKKLGTIVFKDSNELK
WLENFLHPLIRECMLKKAHELEKNHQAYFLDIPLFFEVGGKERYPVSKVVLIYAPRALQIERLLERDKLKETEILQRLNC
QMDIEQKRLMSDYVIDNSFSLKDLAKQVECFLKNLGFVSN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=32.4468085106383, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=32.4468085106383, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI110227607, Length=191, Percent_Identity=30.3664921465969, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI205277394, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI110227603, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI110227601, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786292, Length=186, Percent_Identity=29.5698924731183, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554944, Length=199, Percent_Identity=29.6482412060301, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=199, Percent_Identity=36.1809045226131, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=36.6120218579235, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24658602, Length=163, Percent_Identity=31.9018404907975, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23111; Mature: 23111

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKNAIALTGGIGTGKSTTIKLLESQGYQILDADKIAHQLLQEHRLEIAQHFGSSILEK
CCCCCCEEEECCCCCCCHHHHHEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNRKKLGTIVFKDSNELKWLENFLHPLIRECMLKKAHELEKNHQAYFLDIPLFFEVGG
HHHCHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC
KERYPVSKVVLIYAPRALQIERLLERDKLKETEILQRLNCQMDIEQKRLMSDYVIDNSFS
CCCCCHHHEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
LKDLAKQVECFLKNLGFVSN
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVLKNAIALTGGIGTGKSTTIKLLESQGYQILDADKIAHQLLQEHRLEIAQHFGSSILEK
CCCCCCEEEECCCCCCCHHHHHEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNRKKLGTIVFKDSNELKWLENFLHPLIRECMLKKAHELEKNHQAYFLDIPLFFEVGG
HHHCHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC
KERYPVSKVVLIYAPRALQIERLLERDKLKETEILQRLNCQMDIEQKRLMSDYVIDNSFS
CCCCCHHHEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
LKDLAKQVECFLKNLGFVSN
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]